Ledipasvir is most commonly used in combination with sofosbuvir for treatment in chronic hepatitis C genotype 1 patients. Reference standards of Ledipasvir API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => Methyl ((R)-1-((S)-6-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-L-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazol-6-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptan-5-yl)-3-methyl-1-oxobutan-2-yl)carbamate [catalogue_number] => PA 12 0771000 [category_ids] => ,78,75,70,76,82, [chemical_name] => [weight] => 889 [form] => C49H54F2N8O6 [cas] => 1256393-35-7 [pslug] => 1256393-35-7-methyl-r-1-s-6-5-9-9-difluoro-7-2-1r-3s-4s-2-methoxycarbonyl-l-valyl-2-azabicyclo-2-2-1-heptan-3-yl-1h-benzo-d-imidazol-6-yl-9h-fluoren-2-yl-1h-imidazol-2-yl-5-azaspiro-2-4-heptan-5-yl-3-methyl-1-oxobutan-2-yl-carbamate-pa120771000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 12 0771000
CAS :
Molecular Formula : C49H54F2N8O6
Molecular Weight : 889
stdClass Object ( [pname] => Methyl ((S)-1-((S)-6-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-D-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazol-6-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptan-5-yl)-3-methyl-1-oxobutan-2-yl)carbamate [catalogue_number] => PA 12 0771001 [category_ids] => ,78,75,70,76,82, [chemical_name] => [weight] => 889 [form] => C49H54F2N8O6 [cas] => 1256391-66-8 [pslug] => 1256391-66-8-methyl-s-1-s-6-5-9-9-difluoro-7-2-1r-3s-4s-2-methoxycarbonyl-d-valyl-2-azabicyclo-2-2-1-heptan-3-yl-1h-benzo-d-imidazol-6-yl-9h-fluoren-2-yl-1h-imidazol-2-yl-5-azaspiro-2-4-heptan-5-yl-3-methyl-1-oxobutan-2-yl-carbamate-pa120771001 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 12 0771001
stdClass Object ( [pname] => Ledipasvir 1S,3R,4R-Diastereomer [catalogue_number] => PA 12 0771002 [category_ids] => ,78,75,70,76,82, [chemical_name] => [weight] => 889 [form] => C49H54F2N8O6 [cas] => NA [pslug] => ledipasvir-1s-3r-4r-diastereomer-pa120771002 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 12 0771002
stdClass Object ( [pname] => Ledipasvir 1S,3S,4R-Diastereomer [catalogue_number] => PA 12 0771003 [category_ids] => ,78,75,70,76,82, [chemical_name] => [weight] => 889 [form] => C49H54F2N8O6 [cas] => NA [pslug] => ledipasvir-1s-3s-4r-diastereomer-pa120771003 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 12 0771003
stdClass Object ( [pname] => (S)-5-(tert-Butoxycarbonyl)-5-azaspiro[2.4]heptane-6-carboxylic Acid; [catalogue_number] => PA 12 0771004 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 241.29 [form] => C12H19NO4 [cas] => 1129634-44-1 [pslug] => 1129634-44-1-s-5-tert-butoxycarbonyl-5-azaspiro-2-4-heptane-6-carboxylic-acid-pa120771004 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 12 0771004
Molecular Formula : C12H19NO4
Molecular Weight : 241.29
stdClass Object ( [pname] => Ledipasvir D8 [catalogue_number] => PA STI 089132 [category_ids] => ,98,75,76,78,70,82, [chemical_name] => [weight] => 897.07 [form] => C49H46D8F2N8O6 [cas] => NA [pslug] => ledipasvir-d8-pasti089132 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 089132
Molecular Formula : C49H46D8F2N8O6
Molecular Weight : 897.07
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