imatinib
Metabolites
- Imatinib is a small molecule kinase inhibitor used to treat certain types of cancer. It is occasionally referred to as CGP57148B or STI571. It is used in treating chronic myelogenous leukemia, gastrointestinal stromal tumors and a number of other malignancies. Reference standards of Imatinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Imatinib - Impurity C
[catalogue_number] => PA 09 05030
[category_ids] => ,76,78,70,82,117,
[chemical_name] =>
[weight] => 479.58
[form] => C28H29N7O
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Catalogue No.:PA 09 05030
Molecular Formula : C28H29N7O
Molecular Weight : 479.58
stdClass Object
(
[pname] => N-Desmethyl Imatinib-d8
[catalogue_number] => PA STI 028390
[category_ids] => ,76,78,70,82,117,98,
[chemical_name] =>
[weight] => 487.63
[form] => C28H21D8N7O
[cas] => 1185103-28-9
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Catalogue No.:PA STI 028390
Molecular Formula : C28H21D8N7O
Molecular Weight : 487.63
stdClass Object
(
[pname] => N-(4-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
[catalogue_number] => PA 09 05610
[category_ids] => ,80,71,76,75,78,70,82,
[chemical_name] =>
[weight] => 277.32
[form] => C16H15N5
[cas] => 112696-91-0
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N-(4-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
Catalogue No.:PA 09 05610
Molecular Formula : C16H15N5
Molecular Weight : 277.32
stdClass Object
(
[pname] => Imatinib para-Diaminomethylbenzene
[catalogue_number] => PA 09 0051000
[category_ids] => ,75,76,78,82,
[chemical_name] =>
[weight] => 493.60
[form] => C29H31N7O
[cas] => 1026753-54-7
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Imatinib para-Diaminomethylbenzene
Catalogue No.:PA 09 0051000
Molecular Formula : C29H31N7O
Molecular Weight : 493.60
stdClass Object
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[pname] => Imatinib D4
[catalogue_number] => PA STI 088698
[category_ids] => ,78,75,70,76,82,
[chemical_name] =>
[weight] => 497.64
[form] => C29H27D4N7O
[cas] => 1134803-16-9
[pslug] => 1134803-16-9-imatinib-d4-pasti088698
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Catalogue No.:PA STI 088698
Molecular Formula : C29H27D4N7O
Molecular Weight : 497.64
stdClass Object
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[pname] => N-Boc-N-Desmethyl Imatinib
[catalogue_number] => PA 09 0051001
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 579.71
[form] => C33H37N7O3
[cas] => 1076199-23-9
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N-Boc-N-Desmethyl Imatinib
Catalogue No.:PA 09 0051001
Molecular Formula : C33H37N7O3
Molecular Weight : 579.71
stdClass Object
(
[pname] => 6-Methyl-N1-(4-methyl-6-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine
[catalogue_number] => PA 09 0051002
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 291.36
[form] => C17H17N5
[cas] => 1032314-73-0
[pslug] => 1032314-73-0-6-methyl-n1-4-methyl-6-pyridin-3-yl-pyrimidin-2-yl-benzene-1-3-diamine-pa090051002
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6-Methyl-N1-(4-methyl-6-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine
Catalogue No.:PA 09 0051002
Molecular Formula : C17H17N5
Molecular Weight : 291.36
stdClass Object
(
[pname] => 4-methyl-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
[catalogue_number] => PA 09 0051003
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[chemical_name] =>
[weight] => 395.47
[form] => C24H21N5O
[cas] => 152459-96-6
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4-methyl-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
Catalogue No.:PA 09 0051003
Molecular Formula : C24H21N5O
Molecular Weight : 395.47
stdClass Object
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[pname] => 4-(chloromethyl)benzoic acid
[catalogue_number] => PA 09 0051004
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[chemical_name] =>
[weight] => 170.59
[form] => C8H7ClO2
[cas] => 1642-81-5
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4-(chloromethyl)benzoic acid
Catalogue No.:PA 09 0051004
Molecular Formula : C8H7ClO2
Molecular Weight : 170.59
stdClass Object
(
[pname] => N-(2-methyl-5-nitrophenyl)-[3,4'-bipyridin]-2'-amine
[catalogue_number] => PA 09 0051005
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 306.33
[form] => C17H14N4O2
[cas] => 641615-50-1
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N-(2-methyl-5-nitrophenyl)-[3,4'-bipyridin]-2'-amine
Catalogue No.:PA 09 0051005
Molecular Formula : C17H14N4O2
Molecular Weight : 306.33
stdClass Object
(
[pname] => Desmethyl Imatinib D4
[catalogue_number] => PA STI 089122
[category_ids] => ,98,75,76,78,70,82,
[chemical_name] =>
[weight] => 483.61
[form] => C28H25D4N7O
[cas] => NA
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Catalogue No.:PA STI 089122
Molecular Formula : C28H25D4N7O
Molecular Weight : 483.61
stdClass Object
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[pname] => sec-Butyl 4-((4-methylpiperazin-1-yl)methyl)benzoate
[catalogue_number] => PA 09 0051006
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 290.41
[form] => C17H26N2O2
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sec-Butyl 4-((4-methylpiperazin-1-yl)methyl)benzoate
Catalogue No.:PA 09 0051006
Molecular Formula : C17H26N2O2
Molecular Weight : 290.41
stdClass Object
(
[pname] => N-(4-Methyl-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide
[catalogue_number] => PA 09 0051007
[category_ids] => ,70,75,76,78,82,162,
[chemical_name] =>
[weight] => 522.61
[form] => C29H30N8O2
[cas] => NA
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N-(4-Methyl-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide
Catalogue No.:PA 09 0051007
Molecular Formula : C29H30N8O2
Molecular Weight : 522.61
stdClass Object
(
[pname] => N-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-nitrosopiperazin-1-yl)methyl)benzamide
[catalogue_number] => PA 09 0051008
[category_ids] => ,162,70,75,76,78,82,
[chemical_name] =>
[weight] => 508.59
[form] => C28H28N8O2
[cas] => 2816369-80-7
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N-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-nitrosopiperazin-1-yl)methyl)benzamide
Catalogue No.:PA 09 0051008
Molecular Formula : C28H28N8O2
Molecular Weight : 508.59
stdClass Object
(
[pname] => N-(4-Methyl-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide Acetate
[catalogue_number] => PA 09 0051013
[category_ids] => ,70,75,76,78,82,162,
[chemical_name] =>
[weight] => 582.67
[form] => C31H34N8O4
[cas] => NA
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N-(4-Methyl-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide Acetate
Catalogue No.:PA 09 0051013
Molecular Formula : C31H34N8O4
Molecular Weight : 582.67
stdClass Object
(
[pname] => Imatinib - Impurity C (Hydrochloride Salt)
[catalogue_number] => PA 09 0050031
[category_ids] => ,82,78,76,70,
[chemical_name] =>
[weight] => (479.59). x(36.46)
[form] => (C28H29N7O). x(HCl))
[cas] => 1820893-54-6
[pslug] => 1820893-54-6-imatinib-impurity-c-hydrochloride-salt-pa090050031
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Imatinib - Impurity C (Hydrochloride Salt)
Catalogue No.:PA 09 0050031
Molecular Formula : (C28H29N7O). x(HCl))
Molecular Weight : (479.59). x(36.46)
