Asciminib-impurities | Pharmaffiliates

Asciminib

Asciminib, sold under the brand name Scemblix, is a medication used to treat Philadelphia chromosome-positive chronic myeloid leukemia. It is a protein kinase inhibitor. Reference standards of Asciminib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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(
    [pname] => Asciminib - API Standards 
    [catalogue_number] => PA 01 3630000
    [category_ids] => ,76,78,70,82,
    [chemical_name] => 
    [weight] => 449.84
    [form] => C20H18ClF2N5O3
    [cas] => 1492952-76-7
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PA 01 3630000

Asciminib - API Standards


  • Catalogue No.:PA 01 3630000

  • CAS :

    1492952-76-7

  • Molecular Formula : C20H18ClF2N5O3

  • Molecular Weight : 449.84

stdClass Object
(
    [pname] => (R)-N-(4-(Chlorodifluoromethoxy)phenyl)-6-(3-hydroxypyrrolidin-1-yl)-N-nitroso-5-(1H-pyrazol-3-yl)nicotinamide
    [catalogue_number] => PA 01 3631000
    [category_ids] => ,76,78,70,82,162,
    [chemical_name] => 
    [weight] => 478.84
    [form] => C20H17ClF2N6O4
    [cas] => NA
    [pslug] => r-n-4-chlorodifluoromethoxy-phenyl-6-3-hydroxypyrrolidin-1-yl-n-nitroso-5-1h-pyrazol-3-yl-nicotinamide-pa013631000
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PA 01 3631000

(R)-N-(4-(Chlorodifluoromethoxy)phenyl)-6-(3-hydroxypyrrolidin-1-yl)-N-nitroso-5-(1H-pyrazol-3-yl)nicotinamide


  • Catalogue No.:PA 01 3631000

  • CAS :

    NA

  • Molecular Formula : C20H17ClF2N6O4

  • Molecular Weight : 478.84

stdClass Object
(
    [pname] => Deschloro Asciminib Impurity
    [catalogue_number] => PA 01 3631001
    [category_ids] => ,76,78,70,82,
    [chemical_name] => 
    [weight] => 415.4
    [form] => C20H19F2N5O3
    [cas] => 3033653-93-6
    [pslug] => 3033653-93-6-deschloro-asciminib-impurity-pa013631001
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PA 01 3631001

Deschloro Asciminib Impurity


  • Catalogue No.:PA 01 3631001

  • CAS :

    3033653-93-6

  • Molecular Formula : C20H19F2N5O3

  • Molecular Weight : 415.4

stdClass Object
(
    [pname] => (R)-6-(3-Hydroxypyrrolidin-1-yl)-5-(1H-pyrazol-3-yl)-N-(4-(trifluoromethoxy)phenyl)nicotinamide
    [catalogue_number] => PA 01 3631002
    [category_ids] => ,76,78,70,82,
    [chemical_name] => 
    [weight] => 433.39
    [form] => C20H18F3N5O3
    [cas] => 1492952-55-2
    [pslug] => 1492952-55-2-r-6-3-hydroxypyrrolidin-1-yl-5-1h-pyrazol-3-yl-n-4-trifluoromethoxy-phenyl-nicotinamide-pa013631002
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PA 01 3631002

(R)-6-(3-Hydroxypyrrolidin-1-yl)-5-(1H-pyrazol-3-yl)-N-(4-(trifluoromethoxy)phenyl)nicotinamide


  • Catalogue No.:PA 01 3631002

  • CAS :

    1492952-55-2

  • Molecular Formula : C20H18F3N5O3

  • Molecular Weight : 433.39

stdClass Object
(
    [pname] => Asciminib S-Isomer
    [catalogue_number] => PA 01 3631003
    [category_ids] => ,76,78,70,82,
    [chemical_name] => 
    [weight] => 449.84
    [form] => C20H18ClF2N5O3
    [cas] => 1492952-73-4
    [pslug] => 1492952-73-4-asciminib-s-isomer-pa013631003
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PA 01 3631003

Asciminib S-Isomer


  • Catalogue No.:PA 01 3631003

  • CAS :

    1492952-73-4

  • Molecular Formula : C20H18ClF2N5O3

  • Molecular Weight : 449.84