apatinib

Metabolites - Apatinib is a novel, small molecule, selective vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor and is the second anti-angiogenic drug to be approved in China for the treatment of advanced or metastatic gastric cancer.Reference standards of Apatinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => rac cis-3-Hydroxy Apatinib-d4 Hydrochloride
    [catalogue_number] => PA STI 047290
    [category_ids] => ,80,71,98,76,75,78,70,82,117,
    [chemical_name] => 
    [weight] => 453.96
    [form] => C24H20D4ClN5O2
    [cas] => NA
    [pslug] => rac-cis-3-hydroxy-apatinib-d4-hydrochloride-pasti047290
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rac cis-3-Hydroxy Apatinib-d4 Hydrochloride

Catalogue No.:PA STI 047290
CAS :
NA
Molecular Formula : C₂₄H₂₀D₄ClN₅O₂
Molecular Weight : 453.96

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Details

stdClass Object
(
    [pname] => rac trans-3-Hydroxy Apatinib-d4 Hydrochloride
    [catalogue_number] => PA STI 047300
    [category_ids] => ,80,71,98,76,75,78,70,82,117,
    [chemical_name] => 
    [weight] => 453.96
    [form] => C24H20D4ClN5O2
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rac trans-3-Hydroxy Apatinib-d4 Hydrochloride

Catalogue No.:PA STI 047300
CAS :
NA
Molecular Formula : C₂₄H₂₀D₄ClN₅O₂
Molecular Weight : 453.96

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Details

stdClass Object
(
    [pname] => rac cis-3-Hydroxy Apatinib-d4 3-O-β-D-Glucuronide
    [catalogue_number] => PA STI 047310
    [category_ids] => ,80,95,71,98,76,75,78,70,82,117,
    [chemical_name] => 
    [weight] => 593.62
    [form] => C30H27D4N5O8
    [cas] => NA
    [pslug] => rac-cis-3-hydroxy-apatinib-d4-3-o-beta-d-glucuronide-pasti047310
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rac cis-3-Hydroxy Apatinib-d4 3-O-β-D-Glucuronide

Catalogue No.:PA STI 047310
CAS :
NA
Molecular Formula : C₃₀H₂₇D₄N₅O₈
Molecular Weight : 593.62

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Details

stdClass Object
(
    [pname] => Apatinib
    [catalogue_number] => PA 01 3640000
    [category_ids] => ,80,71,76,75,78,70,82,88,
    [chemical_name] => 
    [weight] => 397.48
    [form] => C24H23N5O
    [cas] => 811803-05-1
    [pslug] => 811803-05-1-apatinib-api-pa013640000
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