lopinavir
Intermediates
- Lopinavir is used against HIV infections as a fixed-dose combination with another protease inhibitor, ritonavir. It is an antiretroviral of the protease inhibitor class. Reference standards of Lopinavir API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Lopinavir
[catalogue_number] => PA 12 32000
[category_ids] => ,77,69,113,78,70,82,
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[weight] => 628.80
[form] => C37H48N4O5
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Catalogue No.:PA 12 32000
Molecular Formula : C37H48N4O5
Molecular Weight : 628.80
stdClass Object
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[pname] => 4,5-Dehydro(pyrimidin-2(1H)-one) Lopinavir
[catalogue_number] => PA 12 32510
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[weight] => 626.78
[form] => C37H46N4O5
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4,5-Dehydro(pyrimidin-2(1H)-one) Lopinavir
Catalogue No.:PA 12 32510
Molecular Formula : C37H46N4O5
Molecular Weight : 626.78
stdClass Object
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[pname] => Lopinavir-d8
[catalogue_number] => PA STI 057050
[category_ids] => ,98,113,78,70,82,
[chemical_name] =>
[weight] => 636.85
[form] => C37H40D8N4O5
[cas] => 1322625-54-6
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Catalogue No.:PA STI 057050
Molecular Formula : C37H40D8N4O5
Molecular Weight : 636.85
stdClass Object
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[pname] => (S)-Tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic Acid-d8
[catalogue_number] => PA STI 082120
[category_ids] => ,97,69,71,78,70,82,98,
[chemical_name] =>
[weight] => 208.28
[form] => C9H8D8N2O3
[cas] => 1323257-58-4
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(S)-Tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic Acid-d8
Catalogue No.:PA STI 082120
Molecular Formula : C9H8D8N2O3
Molecular Weight : 208.28
stdClass Object
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[pname] => (S)-Tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetyl Chloride
[catalogue_number] => PA STI 082250
[category_ids] => ,97,69,71,78,70,82,98,
[chemical_name] =>
[weight] => 218.68
[form] => C9H15ClN2O2
[cas] => 192800-77-4_x0000_
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(S)-Tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetyl Chloride
Catalogue No.:PA STI 082250
Molecular Formula : C9H15ClN2O2
Molecular Weight : 218.68
stdClass Object
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[pname] => Lopinavir - Impurity L
[catalogue_number] => PA 12 32120
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[form] => C22H26N2O4
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Catalogue No.:PA 12 32120
Molecular Formula : C22H26N2O4
Molecular Weight : 382.46
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[pname] => Lopinavir - Impurity T
[catalogue_number] => PA 12 32200
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[form] => C57H66N4O7
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Catalogue No.:PA 12 32200
Molecular Formula : C57H66N4O7
Molecular Weight : 919.18
stdClass Object
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[catalogue_number] => PA 12 32520
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[weight] => 642.84
[form] => C38H50N4O5
[cas] => NA
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3-Methyl-2-(2-oxo-tetrahydro-pyrimidin-1-yl)-pentanoic Acid{1-benzyl-4-[2-(2-6,-dimethyl-phenoxy)-acetylamino]-3-hydroxy-5-phenyl-pentyl}-amide
Catalogue No.:PA 12 32520
Molecular Formula : C38H50N4O5
Molecular Weight : 642.84
stdClass Object
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(S)-N-((2S,4S,5S)-4-(((6-(Cyclopropylamino)-9-((1S,4S)-4-(hydroxymethyl)cyclopent-2-en-1-yl)-9H-purin-2-yl)amino)methoxy)-5-(2-(2,6-dimethylphenoxy)acetamido)-1,6-diphenylhexan-2-yl)-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide
Catalogue No.:PA 12 32530
Molecular Formula : C52H66N10O6
Molecular Weight : 927.16
stdClass Object
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[weight] => 384.51
[form] => C23H32N2O3
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(2S,3S,5S)-2-Amino-3-hydroxy-5-(tert-butyloxycarbonylamino)-1,6-diphenylhexane
Catalogue No.:PA 12 32550
Molecular Formula : C23H32N2O3
Molecular Weight : 384.51
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[pname] => Lopinavir - Impurity A
[catalogue_number] => PA 12 32010
[category_ids] => ,69,70,80,
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[weight] => 466.63
[form] => C27H38N4O3
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Catalogue No.:PA 12 32010
Molecular Formula : C27H38N4O3
Molecular Weight : 466.63
stdClass Object
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[pname] => Lopinavir - Impurity I
[catalogue_number] => PA 12 32090
[category_ids] => ,80,69,70,
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[weight] => 628.81
[form] => C37H48N4O5
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Catalogue No.:PA 12 32090
Molecular Formula : C37H48N4O5
Molecular Weight : 628.81
stdClass Object
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Catalogue No.:PA 12 32130
Molecular Formula : C37H48N4O5
Molecular Weight : 628.81
stdClass Object
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[pname] => (2S,3S,5S)-2-(2,6-Dimethylphenoxyacetyl)amino-3-hydroxy-5-trifluromethylcarbonylamino-1,6-diphenylhexane
[catalogue_number] => PA 12 32540
[category_ids] => ,80,69,70,
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[weight] => 542.6
[form] => C30H33F3N2O4
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(2S,3S,5S)-2-(2,6-Dimethylphenoxyacetyl)amino-3-hydroxy-5-trifluromethylcarbonylamino-1,6-diphenylhexane
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[catalogue_number] => PA 12 32570
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[form] => C47H58N4O7
[cas] => 943250-65-5
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Catalogue No.:PA 12 32570
Molecular Formula : C47H58N4O7
Molecular Weight : 790.99
stdClass Object
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[catalogue_number] => PA STI 088718
[category_ids] => ,98,80,71,78,70,82,
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[weight] => 631.83
[form] => C37H45D3N4O5
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Catalogue No.:PA STI 088718
Molecular Formula : C37H45D3N4O5
Molecular Weight : 631.83
stdClass Object
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[catalogue_number] => PA 12 0321001
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[form] => C37H48N4O6
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Lopinavir Metabolite M-3/M-4
Catalogue No.:PA 12 0321001
Molecular Formula : C37H48N4O6
Molecular Weight : 644.81
stdClass Object
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[catalogue_number] => PA 12 0321002
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Lopinavir System Suitability Mixture
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Catalogue No.:PA 12 0321003
Molecular Formula : C38H50N4O5
Molecular Weight : 642.84
stdClass Object
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[pname] => Lopinavir - Impurity F
[catalogue_number] => PA 12 0320060
[category_ids] => ,82,78,76,75,70,
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[weight] => 474.6
[form] => C29H34N2O4
[cas] => 3023702-68-0
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[weight] => 791
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[pname] => Lopinavir - Impurity D
[catalogue_number] => PA 12 0320040
[category_ids] => ,75,76,78,70,82,
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[weight] => 708.87
[form] => C37H48N4O8S
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Catalogue No.:PA 12 0320040
Molecular Formula : C37H48N4O8S
Molecular Weight : 708.87
stdClass Object
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[catalogue_number] => PA 12 0320030
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[chemical_name] =>
[weight] => 648.85
[form] => C36H52N6O5
[cas] => NA
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Catalogue No.:PA 12 0320030
Molecular Formula : C36H52N6O5
Molecular Weight : 648.85
stdClass Object
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[catalogue_number] => PA 12 0320100
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Catalogue No.:PA 12 0320100
Molecular Formula : C37H48N4O5
Molecular Weight : 628.81
stdClass Object
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Catalogue No.:PA 12 0320050
Molecular Formula : C28H34N2O3
Molecular Weight : 446.59
stdClass Object
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[catalogue_number] => PA 12 0320110
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Catalogue No.:PA 12 0320110
Molecular Formula : C37H48N4O5
Molecular Weight : 628.81
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Catalogue No.:PA 12 0320140
Molecular Formula : C37H48N4O5
Molecular Weight : 628.81
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Catalogue No.:PA 12 0320160
Molecular Formula : C37H48N4O5
Molecular Weight : 628.81
stdClass Object
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[catalogue_number] => PA 12 0320170
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[weight] => 608.78
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Catalogue No.:PA 12 0320170
Molecular Formula : C38H44N2O5
Molecular Weight : 608.78
stdClass Object
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[weight] => 494.64
[form] => C28H38N4O4
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Catalogue No.:PA 12 0320020
Molecular Formula : C28H38N4O4
Molecular Weight : 494.64
stdClass Object
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N-(5-(2-(2,6-dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)pentanamide
Catalogue No.:PA 12 0321004
Molecular Formula : C38H50N4O5
Molecular Weight : 642.84
stdClass Object
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[weight] => 488.63
[form] => C30H36N2O4
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Catalogue No.:PA 12 0320070
Molecular Formula : C30H36N2O4
Molecular Weight : 488.63
stdClass Object
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[weight] => 811.04
[form] => C46H62N6O7
[cas] => NA
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Catalogue No.:PA 12 0320150
Molecular Formula : C46H62N6O7
Molecular Weight : 811.04
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[weight] => 472.59
[form] => C29H32N2O4
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Catalogue No.:PA 12 0320080
Molecular Formula : C29H32N2O4
Molecular Weight : 472.59
stdClass Object
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Lopinavir (IPRS/111/16) - from IPC
stdClass Object
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[weight] => 564.77
[form] => C37H44N2O3
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(2S,3S,5S)-2-(N,N-Dibenzylamino)-3-hydroxy-5-(tert-butyloxycarbonylamino)-1,6-diphenylhexane
Catalogue No.:PA 12 0321005
Molecular Formula : C37H44N2O3
Molecular Weight : 564.77
stdClass Object
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[weight] => 200.24
[form] => C9H16N2O3
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(R)-3-Methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanoic Acid
Catalogue No.:PA 12 0321006
Molecular Formula : C9H16N2O3
Molecular Weight : 200.24
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Catalogue No.:PA 12 0321007
Molecular Formula : C37H48N4O8S
Molecular Weight : 708.87
stdClass Object
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[weight] => 1135.46
[form] => C66H86N8O9
[cas] => 1989516-33-7
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(S)-N-((2S,4S,5S)-4-Hydroxy-5-(2-(4-(2-(((2S,3S,5S)-3-hydroxy-5-((S)-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamido)-1,6-diphenylhexan-2-yl)amino)-2-oxoethoxy)-3,5-dimethylphenyl)acetamido)-1,6-diphenylhexan-2-yl)-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide
Catalogue No.:PA 12 0321009
Molecular Formula : C66H86N8O9
Molecular Weight : 1135.46
stdClass Object
(
[pname] => (S)-N-((2S,4S,5S)-5-(2-(2,6-Dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-4-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)pentanamide
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[weight] => 642.84
[form] => C38H50N4O5
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(S)-N-((2S,4S,5S)-5-(2-(2,6-Dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-4-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)pentanamide
Catalogue No.:PA 12 0321010
Molecular Formula : C38H50N4O5
Molecular Weight : 642.84
stdClass Object
(
[pname] => tert-Butyl ((2S,4S,5S)-5-(2-(2,6-dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate
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[weight] => 546.71
[form] => C33H42N2O5
[cas] => 192725-45-4
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tert-Butyl ((2S,4S,5S)-5-(2-(2,6-dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate
Catalogue No.:PA 12 0321011
Molecular Formula : C33H42N2O5
Molecular Weight : 546.71
stdClass Object
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[pname] => Abacavir Lopinavir Methylene Conjugation Impurity
[catalogue_number] => PA 12 0321012
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[weight] => 927.16
[form] => C52H66N10O6
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Abacavir Lopinavir Methylene Conjugation Impurity
Catalogue No.:PA 12 0321012
Molecular Formula : C52H66N10O6
Molecular Weight : 927.16
stdClass Object
(
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[weight] => 542.6
[form] => C30H33F3N2O4
[cas] => 2125942-48-3
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rel N-((2S,4S,5S)-5-(2-(2,6-dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-2,2,2-trifluoroacetamide
stdClass Object
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[pname] => 1-(9-Benzylidene-2,7-dichloro-9H-fluoren-4-yl)-2-(dibutylamino)ethan-1-ol
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[weight] => 494.5
[form] => C30H33Cl2NO
[cas] => 1276121-35-7
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1-(9-Benzylidene-2,7-dichloro-9H-fluoren-4-yl)-2-(dibutylamino)ethan-1-ol
