Elexacaftor-impurities | Pharmaffiliates

Elexacaftor

Elexacaftor is a small molecule CFTR corrector used in combination with tezacaftor and ivacaftor for the treatment of cystic fibrosis patients with one F508del-CFTR mutation. Reference standards of Elexacaftor API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Elexacaftor - API Standards 
    [catalogue_number] => PA 05 1861000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 597.66
    [form] => C26H34F3N7O4S
    [cas] => 2216712-66-0
    [pslug] => 2216712-66-0-elexacaftor-api-pa051861000
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PA 05 1861000

Elexacaftor - API Standards


  • Catalogue No.:PA 05 1861000

  • CAS :

    2216712-66-0

  • Molecular Formula : C26H34F3N7O4S

  • Molecular Weight : 597.66

stdClass Object
(
    [pname] => 2-Chloro-N-((1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl)-6-(3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl)nicotinamide
    [catalogue_number] => PA 05 1861001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 520.91
    [form] => C19H20ClF3N6O4S
    [cas] => 2229861-18-9
    [pslug] => 2229861-18-9-2-chloro-n-1-3-dimethyl-1h-pyrazol-4-yl-sulfonyl-6-3-3-3-3-trifluoro-2-2-dimethylpropoxy-1h-pyrazol-1-yl-nicotinamide-pa051861001
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PA 05 1861001

2-Chloro-N-((1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl)-6-(3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl)nicotinamide


  • Catalogue No.:PA 05 1861001

  • CAS :

    2229861-18-9

  • Molecular Formula : C19H20ClF3N6O4S

  • Molecular Weight : 520.91

stdClass Object
(
    [pname] => N-Desmethyl Elexacaftor
    [catalogue_number] => PA 05 1861002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 583.63
    [form] => C25H32F3N7O4S
    [cas] => 2229860-93-7
    [pslug] => 2229860-93-7-n-desmethyl-elexacaftor-pa051861002
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PA 05 1861002

N-Desmethyl Elexacaftor


  • Catalogue No.:PA 05 1861002

  • CAS :

    2229860-93-7

  • Molecular Formula : C25H32F3N7O4S

  • Molecular Weight : 583.63

stdClass Object
(
    [pname] => (R)-Elexacaftor
    [catalogue_number] => PA 05 1861003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 597.66
    [form] => C26H34F3N7O4S
    [cas] => 2229860-99-3
    [pslug] => 2229860-99-3-r-elexacaftor-pa051861003
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PA 05 1861003

(R)-Elexacaftor


  • Catalogue No.:PA 05 1861003

  • CAS :

    2229860-99-3

  • Molecular Formula : C26H34F3N7O4S

  • Molecular Weight : 597.66