Cefadroxil-impurities | Pharmaffiliates

cefadroxil

Cefadroxil is used to treat a wide variety of bacterial infections. It is a bactericidal antibiotic. Reference standards of Cefadroxil API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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(
    [pname] => Cefadroxil - Impurity A
    [catalogue_number] => PA 03 19010
    [category_ids] => ,79,80,70,78,70,82,
    [chemical_name] => 
    [weight] => 167.16
    [form] => C8H9NO3
    [cas] => 22818-40-2
    [pslug] => 22818-40-2-cefadroxil-impurity-a-pa0319010
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PA 03 19010

Cefadroxil - Impurity A


  • Catalogue No.:PA 03 19010

  • CAS :

    22818-40-2

  • Molecular Formula : C8H9NO3

  • Molecular Weight : 167.16

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stdClass Object
(
    [pname] => Cefadroxil - Impurity D
    [catalogue_number] => PA 03 19040
    [category_ids] => ,69,70,71,78,79,80,82,88,
    [chemical_name] => 
    [weight] => 363.39
    [form] => C16H17N3O5S
    [cas] => 144790-28-3
    [pslug] => 144790-28-3-cefadroxil-impurity-d-pa0319040
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    [offers_product_code] => PA 03 19040
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PA 03 19040

Cefadroxil - Impurity D


  • Catalogue No.:PA 03 19040

  • CAS :

    144790-28-3

  • Molecular Formula : C16H17N3O5S

  • Molecular Weight : 363.39

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stdClass Object
(
    [pname] => Δ2-Cefadroxil
    [catalogue_number] => PA 03 19510
    [category_ids] => ,69,70,71,78,79,80,82,88,
    [chemical_name] => 
    [weight] => 363.39
    [form] => C16H17N3O5S
    [cas] => 147103-94-4
    [pslug] => 147103-94-4-delta-2-cefadroxil-pa0319510
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PA 03 19510

Δ2-Cefadroxil


  • Catalogue No.:PA 03 19510

  • CAS :

    147103-94-4

  • Molecular Formula : C16H17N3O5S

  • Molecular Weight : 363.39

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stdClass Object
(
    [pname] => Cefadroxil - Impurity F
    [catalogue_number] => PA 03 19060
    [category_ids] => ,70,71,78,82,
    [chemical_name] => 
    [weight] => 512.54
    [form] => C24H24N4O7S
    [cas] => 147103-95-5
    [pslug] => 147103-95-5-cefadroxil-impurity-f-pa0319060
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    [offers_product_id] => 34455
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PA 03 19060

Cefadroxil - Impurity F


  • Catalogue No.:PA 03 19060

  • CAS :

    147103-95-5

  • Molecular Formula : C24H24N4O7S

  • Molecular Weight : 512.54

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stdClass Object
(
    [pname] => (6R,7R)-7-((Ethoxycarbonyl)amino)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
    [catalogue_number] => PA 03 19620
    [category_ids] => ,70,78,82,
    [chemical_name] => 
    [weight] => 286.3
    [form] => C11H14N2O5S
    [cas] => 72820-16-7
    [pslug] => 72820-16-7-6r-7r-7-ethoxycarbonyl-amino-3-methyl-8-oxo-5-thia-1-azabicyclo-4-2-0-oct-2-ene-2-carboxylic-acid-pa0319620
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PA 03 19620

(6R,7R)-7-((Ethoxycarbonyl)amino)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid


  • Catalogue No.:PA 03 19620

  • CAS :

    72820-16-7

  • Molecular Formula : C11H14N2O5S

  • Molecular Weight : 286.3

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stdClass Object
(
    [pname] => Cefadroxil R-sulfoxide
    [catalogue_number] => PA 03 19650
    [category_ids] => ,70,78,82,
    [chemical_name] => 
    [weight] => 379.39
    [form] => C16H17N3O6S
    [cas] => NA
    [pslug] => cefadroxil-r-sulfoxide-pa0319650
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PA 03 19650

Cefadroxil R-sulfoxide


  • Catalogue No.:PA 03 19650

  • CAS :

    NA

  • Molecular Formula : C16H17N3O6S

  • Molecular Weight : 379.39

20 % OFF
stdClass Object
(
    [pname] => Cefadroxil S-sulfoxide
    [catalogue_number] => PA 03 19660
    [category_ids] => ,70,78,82,
    [chemical_name] => 
    [weight] => 379.39
    [form] => C16H17N3O6S
    [cas] => NA
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PA 03 19660

Cefadroxil S-sulfoxide


  • Catalogue No.:PA 03 19660

  • CAS :

    NA

  • Molecular Formula : C16H17N3O6S

  • Molecular Weight : 379.39

20 % OFF
stdClass Object
(
    [pname] => (6R)-2-Amino-7-(2-amino-2-(4-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylic Acid 5-oxide
    [catalogue_number] => PA 03 0191000
    [category_ids] => ,79,80,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 396.42
    [form] => C16H20N4O6S
    [cas] => NA
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PA 03 0191000

(6R)-2-Amino-7-(2-amino-2-(4-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylic Acid 5-oxide


  • Catalogue No.:PA 03 0191000

  • CAS :

    NA

  • Molecular Formula : C16H20N4O6S

  • Molecular Weight : 396.42

20 % OFF
stdClass Object
(
    [pname] => Terramide A
    [catalogue_number] => PA 03 19520
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 258.31
    [form] => C12H22N2O4
    [cas] => 104187-50-0
    [pslug] => 104187-50-0-terramide-a-pa0319520
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PA 03 19520

Terramide A


  • Catalogue No.:PA 03 19520

  • CAS :

    104187-50-0

  • Molecular Formula : C12H22N2O4

  • Molecular Weight : 258.31

stdClass Object
(
    [pname] => Terramide B
    [catalogue_number] => PA 03 19530
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 244.29
    [form] => C11H20N2O4
    [cas] => 104187-49-7
    [pslug] => 104187-49-7-terramide-b-pa0319530
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PA 03 19530

Terramide B


  • Catalogue No.:PA 03 19530

  • CAS :

    104187-49-7

  • Molecular Formula : C11H20N2O4

  • Molecular Weight : 244.29

stdClass Object
(
    [pname] => 3,6-Di((S)-sec-butyl)-1,4-dihydroxypiperazine-2,5-dione
    [catalogue_number] => PA 03 19540
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 258.31
    [form] => C12H22N2O4
    [cas] => 1264728-35-9
    [pslug] => 1264728-35-9-3-6-di-s-sec-butyl-1-4-dihydroxypiperazine-2-5-dione-pa0319540
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PA 03 19540

3,6-Di((S)-sec-butyl)-1,4-dihydroxypiperazine-2,5-dione


  • Catalogue No.:PA 03 19540

  • CAS :

    1264728-35-9

  • Molecular Formula : C12H22N2O4

  • Molecular Weight : 258.31

stdClass Object
(
    [pname] => (6R,7R)-7-((R)-2-Amino-2-(4-hydroxyphenyl)acetamido)-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
    [catalogue_number] => PA 03 19550
    [category_ids] => ,79,80,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 393.41
    [form] => C17H19N3O6S
    [cas] => NA
    [pslug] => 6r-7r-7-r-2-amino-2-4-hydroxyphenyl-acetamido-3-methoxymethyl-8-oxo-5-thia-1-azabicyclo-4-2-0-oct-2-ene-2-carboxylic-acid-pa0319550
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PA 03 19550

(6R,7R)-7-((R)-2-Amino-2-(4-hydroxyphenyl)acetamido)-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid


  • Catalogue No.:PA 03 19550

  • CAS :

    NA

  • Molecular Formula : C17H19N3O6S

  • Molecular Weight : 393.41

stdClass Object
(
    [pname] => Cefadroxil-d4 Monohydrate
    [catalogue_number] => PA STI 088083
    [category_ids] => ,98,88,82,78,70,
    [chemical_name] => 
    [weight] => 385.43
    [form] => C16H15D4N3O6S
    [cas] => 1426174-38-0
    [pslug] => 1426174-38-0-cefadroxil-d4-monohydrate-pasti088083
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PA STI 088083

Cefadroxil-d4 Monohydrate


  • Catalogue No.:PA STI 088083

  • CAS :

    1426174-38-0

  • Molecular Formula : C16H15D4N3O6S

  • Molecular Weight : 385.43

stdClass Object
(
    [pname] => Cefadroxil - Impurity C
    [catalogue_number] => PA 03 19030
    [category_ids] => ,75,78,70,
    [chemical_name] => 
    [weight] => 381.40
    [form] => C16H19N3O6S
    [cas] => NA
    [pslug] => cefadroxil-impurity-c-pa0319030
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PA 03 19030

Cefadroxil - Impurity C


  • Catalogue No.:PA 03 19030

  • CAS :

    NA

  • Molecular Formula : C16H19N3O6S

  • Molecular Weight : 381.40

stdClass Object
(
    [pname] => Cefadroxil Sulfoxide
    [catalogue_number] => PA 03 19560
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 379.39
    [form] => C16H17N3O6S
    [cas] => 182290-77-3
    [pslug] => 182290-77-3-cefadroxil-sulfoxide-pa0319560
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PA 03 19560

Cefadroxil Sulfoxide


  • Catalogue No.:PA 03 19560

  • CAS :

    182290-77-3

  • Molecular Formula : C16H17N3O6S

  • Molecular Weight : 379.39

stdClass Object
(
    [pname] => Cefadroxil Dimer
    [catalogue_number] => PA 03 19570
    [category_ids] => ,70,78,82,
    [chemical_name] => 
    [weight] => 708.76
    [form] => C32H32N6O9S2
    [cas] => 2378158-45-1
    [pslug] => 2378158-45-1-cefadroxil-dimer-pa0319570
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PA 03 19570

Cefadroxil Dimer


  • Catalogue No.:PA 03 19570

  • CAS :

    2378158-45-1

  • Molecular Formula : C32H32N6O9S2

  • Molecular Weight : 708.76

stdClass Object
(
    [pname] => O-Ethoxycarbonyl Cefadroxil
    [catalogue_number] => PA 03 19580
    [category_ids] => ,70,78,82,
    [chemical_name] => 
    [weight] => 435.45
    [form] => C19H21N3O7S
    [cas] => 2378158-44-0
    [pslug] => 2378158-44-0-o-ethoxycarbonyl-cefadroxil-pa0319580
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PA 03 19580

O-Ethoxycarbonyl Cefadroxil


  • Catalogue No.:PA 03 19580

  • CAS :

    2378158-44-0

  • Molecular Formula : C19H21N3O7S

  • Molecular Weight : 435.45

stdClass Object
(
    [pname] => (6R,7R)-7-((R)-2-((S)-2-Amino-2-(4-hydroxyphenyl)acetamido)-2-(4-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
    [catalogue_number] => PA 03 19590
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 512.54
    [form] => C24H24N4O7S
    [cas] => NA
    [pslug] => 6r-7r-7-r-2-s-2-amino-2-4-hydroxyphenyl-acetamido-2-4-hydroxyphenyl-acetamido-3-methyl-8-oxo-5-thia-1-azabicyclo-4-2-0-oct-2-ene-2-carboxylic-acid-pa0319590
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PA 03 19590

(6R,7R)-7-((R)-2-((S)-2-Amino-2-(4-hydroxyphenyl)acetamido)-2-(4-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid


  • Catalogue No.:PA 03 19590

  • CAS :

    NA

  • Molecular Formula : C24H24N4O7S

  • Molecular Weight : 512.54

stdClass Object
(
    [pname] => (6R,7R)-7-((S)-2-Amino-2-(4-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid 5-oxide
    [catalogue_number] => PA 03 19600
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 379.39
    [form] => C16H17N3O6S
    [cas] => NA
    [pslug] => 6r-7r-7-s-2-amino-2-4-hydroxyphenyl-acetamido-3-methyl-8-oxo-5-thia-1-azabicyclo-4-2-0-oct-2-ene-2-carboxylic-acid-5-oxide-pa0319600
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PA 03 19600

(6R,7R)-7-((S)-2-Amino-2-(4-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid 5-oxide


  • Catalogue No.:PA 03 19600

  • CAS :

    NA

  • Molecular Formula : C16H17N3O6S

  • Molecular Weight : 379.39

stdClass Object
(
    [pname] => (6R,7R)-7-((R)-2-((Ethoxycarbonyl)amino)-2-(4-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
    [catalogue_number] => PA 03 19610
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 435.45
    [form] => C19H21N3O7S
    [cas] => NA
    [pslug] => 6r-7r-7-r-2-ethoxycarbonyl-amino-2-4-hydroxyphenyl-acetamido-3-methyl-8-oxo-5-thia-1-azabicyclo-4-2-0-oct-2-ene-2-carboxylic-acid-pa0319610
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PA 03 19610

(6R,7R)-7-((R)-2-((Ethoxycarbonyl)amino)-2-(4-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid


  • Catalogue No.:PA 03 19610

  • CAS :

    NA

  • Molecular Formula : C19H21N3O7S

  • Molecular Weight : 435.45

stdClass Object
(
    [pname] => 3-Ethyl Cefadroxil
    [catalogue_number] => PA 03 19630
    [category_ids] => ,70,78,82,
    [chemical_name] => 
    [weight] => 377.42
    [form] => C17H19N3O5S
    [cas] => 2243976-70-5
    [pslug] => 2243976-70-5-3-ethyl-cefadroxil-pa0319630
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PA 03 19630

3-Ethyl Cefadroxil


  • Catalogue No.:PA 03 19630

  • CAS :

    2243976-70-5

  • Molecular Formula : C17H19N3O5S

  • Molecular Weight : 377.42

stdClass Object
(
    [pname] => N-Phenylglycyl delta-3 cefadroxil
    [catalogue_number] => PA 03 19640
    [category_ids] => ,70,78,82,
    [chemical_name] => 
    [weight] => 512.54
    [form] => C24H24N4O7S
    [cas] => NA
    [pslug] => n-phenylglycyl-delta-3-cefadroxil-pa0319640
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PA 03 19640

N-Phenylglycyl delta-3 cefadroxil


  • Catalogue No.:PA 03 19640

  • CAS :

    NA

  • Molecular Formula : C24H24N4O7S

  • Molecular Weight : 512.54

stdClass Object
(
    [pname] => 7-((R)-2-Amino-2-(4-hydroxyphenyl)acetamido)-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
    [catalogue_number] => PAI 03 033010
    [category_ids] => ,70,
    [chemical_name] => 
    [weight] => 375.40
    [form] => C17H17N3O5S
    [cas] => NA
    [pslug] => 7-r-2-amino-2-4-hydroxyphenyl-acetamido-8-oxo-3-vinyl-5-thia-1-azabicyclo-4-2-0-oct-2-ene-2-carboxylic-acid-pai03033010
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PAI 03 033010

7-((R)-2-Amino-2-(4-hydroxyphenyl)acetamido)-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid


  • Catalogue No.:PAI 03 033010

  • CAS :

    NA

  • Molecular Formula : C17H17N3O5S

  • Molecular Weight : 375.40

stdClass Object
(
    [pname] => (6R,7R)-7-((R)-2-(((Benzyloxy)carbonyl)amino)-2-(4-(((benzyloxy)carbonyl)oxy)phenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
    [catalogue_number] => PAI 03 033020
    [category_ids] => ,70,
    [chemical_name] => 
    [weight] => 631.66
    [form] => C32H29N3O9S
    [cas] => 744150-70-7
    [pslug] => 744150-70-7-6r-7r-7-r-2-benzyloxy-carbonyl-amino-2-4-benzyloxy-carbonyl-oxy-phenyl-acetamido-3-methyl-8-oxo-5-thia-1-azabicyclo-4-2-0-oct-2-ene-2-carboxylic-acid-pai03033020
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PAI 03 033020

(6R,7R)-7-((R)-2-(((Benzyloxy)carbonyl)amino)-2-(4-(((benzyloxy)carbonyl)oxy)phenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid


  • Catalogue No.:PAI 03 033020

  • CAS :

    744150-70-7

  • Molecular Formula : C32H29N3O9S

  • Molecular Weight : 631.66

stdClass Object
(
    [pname] => Benzyl (6R,7R)-7-((R)-2-((6R,7R)-7-((R)-2-(((benzyloxy)carbonyl)amino)-2-(4-(((benzyloxy)carbonyl)oxy)phenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxamido)-2-(4-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
    [catalogue_number] => PAI 03 033030
    [category_ids] => ,70,
    [chemical_name] => 
    [weight] => 1067.15
    [form] => C55H50N6O13S2
    [cas] => NA
    [pslug] => benzyl-6r-7r-7-r-2-6r-7r-7-r-2-benzyloxy-carbonyl-amino-2-4-benzyloxy-carbonyl-oxy-phenyl-acetamido-3-methyl-8-oxo-5-thia-1-azabicyclo-4-2-0-oct-2-ene-2-carboxamido-2-4-hydroxyphenyl-acetamido-3-methyl-8-oxo-5-thia-1-azabicyclo-4-2-0-oct-2-ene-2-carboxylate-pai03033030
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PAI 03 033030

Benzyl (6R,7R)-7-((R)-2-((6R,7R)-7-((R)-2-(((benzyloxy)carbonyl)amino)-2-(4-(((benzyloxy)carbonyl)oxy)phenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxamido)-2-(4-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate


  • Catalogue No.:PAI 03 033030

  • CAS :

    NA

  • Molecular Formula : C55H50N6O13S2

  • Molecular Weight : 1067.15

stdClass Object
(
    [pname] => Benzyl (6R,7R)-7-((R)-2-(4-(benzyloxy)phenyl)-2-(((Z)-4-methoxy-4-oxobut-2-en-2-yl)amino)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
    [catalogue_number] => PAI 03 033040
    [category_ids] => ,70,
    [chemical_name] => 
    [weight] => 641.74
    [form] => C35H35N3O7S
    [cas] => NA
    [pslug] => benzyl-6r-7r-7-r-2-4-benzyloxy-phenyl-2-z-4-methoxy-4-oxobut-2-en-2-yl-amino-acetamido-3-methyl-8-oxo-5-thia-1-azabicyclo-4-2-0-oct-2-ene-2-carboxylate-pai03033040
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PAI 03 033040

Benzyl (6R,7R)-7-((R)-2-(4-(benzyloxy)phenyl)-2-(((Z)-4-methoxy-4-oxobut-2-en-2-yl)amino)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate


  • Catalogue No.:PAI 03 033040

  • CAS :

    NA

  • Molecular Formula : C35H35N3O7S

  • Molecular Weight : 641.74

stdClass Object
(
    [pname] => Benzyl (6R,7R)-7-((R)-2-amino-2-(4-(benzyloxy)phenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
    [catalogue_number] => PAI 03 033050
    [category_ids] => ,70,
    [chemical_name] => 
    [weight] => 543.64
    [form] => C30H29N3O5S
    [cas] => NA
    [pslug] => benzyl-6r-7r-7-r-2-amino-2-4-benzyloxy-phenyl-acetamido-3-methyl-8-oxo-5-thia-1-azabicyclo-4-2-0-oct-2-ene-2-carboxylate-pai03033050
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PAI 03 033050

Benzyl (6R,7R)-7-((R)-2-amino-2-(4-(benzyloxy)phenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate


  • Catalogue No.:PAI 03 033050

  • CAS :

    NA

  • Molecular Formula : C30H29N3O5S

  • Molecular Weight : 543.64

stdClass Object
(
    [pname] => 2-((2-Amino-2-(4-hydroxyphenyl)acetamido)(carboxy)methyl)-5-methyl-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid
    [catalogue_number] => PA 03 0191003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 381.4
    [form] => C16H19N3O6S
    [cas] => 147103-96-6
    [pslug] => 147103-96-6-2-2-amino-2-4-hydroxyphenyl-acetamido-carboxy-methyl-5-methyl-5-6-dihydro-2h-1-3-thiazine-4-carboxylic-acid-pa030191003
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PA 03 0191003

2-((2-Amino-2-(4-hydroxyphenyl)acetamido)(carboxy)methyl)-5-methyl-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid


  • Catalogue No.:PA 03 0191003

  • CAS :

    147103-96-6

  • Molecular Formula : C16H19N3O6S

  • Molecular Weight : 381.4

stdClass Object
(
    [pname] => Cefadroxil-d4 Trifluoroacetate
    [catalogue_number] => PA STI 089302
    [category_ids] => ,78,70,82,88,98,
    [chemical_name] => 
    [weight] => 481.44
    [form] => C18H14D4F3N3O7S
    [cas] => NA
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PA STI 089302

Cefadroxil-d4 Trifluoroacetate


  • Catalogue No.:PA STI 089302

  • CAS :

    NA

  • Molecular Formula : C18H14D4F3N3O7S

  • Molecular Weight : 481.44