Tenecteplase, sold under the trade names TNKase, Metalyse and Elaxim, is an enzyme used as a thrombolytic drug. it is a modified form of recombinant human tissue plasminogen activator used in the emergency treatment of myocardial infarction and pulmonary emboli. Reference standards of Tenecteplase API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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