Spironolactone is used for the treatment of heart failures and kidney diseases. It is metabolised in liver and major metabolites of spironolactone are 7α-TMS,6β-OH-7α-TMS and canrenone,. Reference standards of Spironolactone API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => Spironolactone - Impurity A [catalogue_number] => PA 19 18010 [category_ids] => 87,82,78,75,70,69 [chemical_name] => [weight] => 414.56 [form] => C24H30O4S [cas] => 132458-33-4 [pslug] => 132458-33-4-spironolactone-impurity-a-pa1918010 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 18010
CAS :
Molecular Formula : C24H30O4S
Molecular Weight : 414.56
stdClass Object ( [pname] => 7α-Thiomethyl Spironolactone-d7 (Major) [catalogue_number] => PA STI 082790 [category_ids] => ,76,75,78,70,82,87,98, [chemical_name] => [weight] => 395.61 [form] => C23H25D7O3S [cas] => NA [pslug] => 7-alpha-thiomethyl-spironolactone-d7-major-pasti082790 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 082790
Molecular Formula : C23H25D7O3S
Molecular Weight : 395.61
stdClass Object ( [pname] => Spironolactone - Impurity B [catalogue_number] => PA 19 18020 [category_ids] => ,80,76,75,78,70,82, [chemical_name] => [weight] => 495.47 [form] => C24H31BrO4S [cas] => NA [pslug] => spironolactone-impurity-b-pa1918020 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 18020
Molecular Formula : C24H31BrO4S
Molecular Weight : 495.47
stdClass Object ( [pname] => Spironolactone - Impurity G [catalogue_number] => PA 19 18070 [category_ids] => ,80,76,75,78,70,82, [chemical_name] => [weight] => 432.58 [form] => C24H32O5S [cas] => 880106-10-5 [pslug] => 880106-10-5-spironolactone-impurity-g-pa1918070 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 18070
Molecular Formula : C24H32O5S
Molecular Weight : 432.58
stdClass Object ( [pname] => Spironolactone - Impurity H [catalogue_number] => PA 19 18080 [category_ids] => ,80,76,75,78,70,82, [chemical_name] => [weight] => 298.43 [form] => C20H26O2 [cas] => 53866-24-3 [pslug] => 53866-24-3-spironolactone-impurity-h-pa1918080 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 18080
Molecular Formula : C20H26O2
Molecular Weight : 298.43
stdClass Object ( [pname] => (8R,9S,10R,13S,14S,17S)-17-Hydroxy-17-(3-hydroxyprop-1-yn-1-yl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one [catalogue_number] => PAI 19 018001 [category_ids] => ,78,70,75,76,82, [chemical_name] => [weight] => 342.48 [form] => C22H30O3 [cas] => 55542-26-2 [pslug] => 55542-26-2-8r-9s-10r-13s-14s-17s-17-hydroxy-17-3-hydroxyprop-1-yn-1-yl-10-13-dimethyl-1-2-6-7-8-9-10-11-12-13-14-15-16-17-tetradecahydro-3h-cyclopenta-a-phenanthren-3-one-pai19018001 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PAI 19 018001
Molecular Formula : C22H30O3
Molecular Weight : 342.48
stdClass Object ( [pname] => (8R,9S,10R,13S,14S,17R)-17-Hydroxy-17-(3-hydroxyprop-1-en-1-yl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one [catalogue_number] => PAI 19 018002 [category_ids] => ,78,70,75,76,82, [chemical_name] => [weight] => 344.5 [form] => C22H32O3 [cas] => NA [pslug] => -8r-9s-10r-13s-14s-17r-17-hydroxy-17-3-hydroxyprop-1-en-1-yl-10-13-dimethyl-1-2-6-7-8-9-10-11-12-13-14-15-16-17-tetradecahydro-3h-cyclopenta-a-phenanthren-3-one-pai19018002 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PAI 19 018002
Molecular Formula : C22H32O3
Molecular Weight : 344.5
stdClass Object ( [pname] => (8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H)-dione [catalogue_number] => PAI 19 018003 [category_ids] => ,78,70,75,76,82, [chemical_name] => [weight] => 340.46 [form] => C22H28O3 [cas] => 52845-59-7 [pslug] => 52845-59-7-8r-9s-10r-13s-14s-17r-10-13-dimethyl-1-6-7-8-9-10-11-12-13-14-15-16-dodecahydro-5h-spiro-cyclopenta-a-phenanthrene-17-2-furan-3-5-2h-dione-pai19018003 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PAI 19 018003
Molecular Formula : C22H28O3
Molecular Weight : 340.46
stdClass Object ( [pname] => (8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H)-dione [catalogue_number] => PAI 19 018004 [category_ids] => ,78,70,75,76,82, [chemical_name] => [weight] => 338.45 [form] => C22H26O3 [cas] => NA [pslug] => -8r-9s-10r-13s-14s-17r-10-13-dimethyl-1-8-9-10-11-12-13-14-15-16-decahydro-5h-spiro-cyclopenta-a-phenanthrene-17-2-furan-3-5-2h-dione-pai19018004 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PAI 19 018004
Molecular Formula : C22H26O3
Molecular Weight : 338.45
stdClass Object ( [pname] => Ethyl 3-((3S,8R,9S,10R,13S,14S,17S)-3,17-dihydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propiolate [catalogue_number] => PAI 19 018005 [category_ids] => ,78,75,70,76,82, [chemical_name] => [weight] => 386.53 [form] => C24H34O4 [cas] => NA [pslug] => -ethyl-3-3s-8r-9s-10r-13s-14s-17s-3-17-dihydroxy-10-13-dimethyl-2-3-4-7-8-9-10-11-12-13-14-15-16-17-tetradecahydro-1h-cyclopenta-a-phenanthren-17-yl-propiolate-pai19018005 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PAI 19 018005
Molecular Formula : C24H34O4
Molecular Weight : 386.53
stdClass Object ( [pname] => Ethyl (E)-3-((3S,8R,9S,10R,13S,14S,17R)-3,17-dihydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)acrylate [catalogue_number] => PAI 19 018006 [category_ids] => ,78,75,70,76,82, [chemical_name] => [weight] => 388.55 [form] => C24H36O4 [cas] => NA [pslug] => -ethyl-e-3-3s-8r-9s-10r-13s-14s-17r-3-17-dihydroxy-10-13-dimethyl-2-3-4-7-8-9-10-11-12-13-14-15-16-17-tetradecahydro-1h-cyclopenta-a-phenanthren-17-yl-acrylate-pai19018006 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PAI 19 018006
Molecular Formula : C24H36O4
Molecular Weight : 388.55
stdClass Object ( [pname] => (3S,8R,9S,10R,13S,14S,17R)-3-Hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-5'-one [catalogue_number] => PAI 19 018007 [category_ids] => ,78,75,70,76,82, [chemical_name] => [weight] => 342.48 [form] => C22H30O3 [cas] => NA [pslug] => -3s-8r-9s-10r-13s-14s-17r-3-hydroxy-10-13-dimethyl-1-2-3-4-7-8-9-10-11-12-13-14-15-16-tetradecahydro-5h-spiro-cyclopenta-a-phenanthrene-17-2-furan-5-one-pai19018007 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PAI 19 018007
stdClass Object ( [pname] => (3β)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]androst-5-en-17-one [catalogue_number] => PAI 19 018008 [category_ids] => ,78,75,70,76,82, [chemical_name] => [weight] => 402.69 [form] => C25H42O2Si [cas] => 42151-23-5 [pslug] => 42151-23-5-3beta-3-1-1-dimethylethyl-dimethylsilyl-oxy-androst-5-en-17-one-pai19018008 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PAI 19 018008
Molecular Formula : C25H42O2Si
Molecular Weight : 402.69
stdClass Object ( [pname] => Ethyl 3-((3S,8R,9S,10R,13S,14S,17S)-3-((tert-butyldimethylsilyl)oxy)-17-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propiolate [catalogue_number] => PAI 19 018009 [category_ids] => ,78,75,70,76,82, [chemical_name] => [weight] => 500.8 [form] => C30H48O4Si [cas] => NA [pslug] => -ethyl-3-3s-8r-9s-10r-13s-14s-17s-3-tert-butyldimethylsilyl-oxy-17-hydroxy-10-13-dimethyl-2-3-4-7-8-9-10-11-12-13-14-15-16-17-tetradecahydro-1h-cyclopenta-a-phenanthren-17-yl-propiolate-pai19018009 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PAI 19 018009
Molecular Formula : C30H48O4Si
Molecular Weight : 500.8
stdClass Object ( [pname] => Ethyl (E)-3-((3S,8R,9S,10R,13S,14S,17R)-3-((tert-butyldimethylsilyl)oxy)-17-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)acrylate [catalogue_number] => PAI 19 018010 [category_ids] => ,78,75,70,76,82, [chemical_name] => [weight] => 502.81 [form] => C30H50O4Si [cas] => NA [pslug] => -ethyl-e-3-3s-8r-9s-10r-13s-14s-17r-3-tert-butyldimethylsilyl-oxy-17-hydroxy-10-13-dimethyl-2-3-4-7-8-9-10-11-12-13-14-15-16-17-tetradecahydro-1h-cyclopenta-a-phenanthren-17-yl-acrylate-pai19018010 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PAI 19 018010
Molecular Formula : C30H50O4Si
Molecular Weight : 502.81
stdClass Object ( [pname] => (3S,8R,9S,10R,13S,14S,17R)-3-((tert-Butyldimethylsilyl)oxy)-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-5'-one [catalogue_number] => PAI 19 018011 [category_ids] => ,78,75,70,76,82, [chemical_name] => [weight] => 456.74 [form] => C28H44O3Si [cas] => NA [pslug] => -3s-8r-9s-10r-13s-14s-17r-3-tert-butyldimethylsilyl-oxy-10-13-dimethyl-1-2-3-4-7-8-9-10-11-12-13-14-15-16-tetradecahydro-5h-spiro-cyclopenta-a-phenanthrene-17-2-furan-5-one-pai19018011 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PAI 19 018011
Molecular Formula : C28H44O3Si
Molecular Weight : 456.74
stdClass Object ( [pname] => 7α-Thiomethyl spironolactone [catalogue_number] => PA 19 0181000 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 388.57 [form] => C23H32O3S [cas] => 38753-77-4 [pslug] => 38753-77-4-7alpha-thiomethyl-spironolactone-pa190181000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 0181000
Molecular Formula : C23H32O3S
Molecular Weight : 388.57
stdClass Object ( [pname] => 7α-Thio spironolactone [catalogue_number] => PA 19 0181001 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 374.54 [form] => C22H30O3S [cas] => 38753-76-3 [pslug] => 38753-76-3-7alpha-thio-spironolactone-pa190181001 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 0181001
Molecular Formula : C22H30O3S
Molecular Weight : 374.54
stdClass Object ( [pname] => Spironolactone (IPRS/36/18)-from IPC [catalogue_number] => PA IPRS 36 18 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => NA [form] => NA [cas] => NA [pslug] => spironolactone-iprs-36-18-from-ipc-paiprs3618 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA IPRS 36 18
Molecular Formula : NA
Molecular Weight : NA
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