sorafenib

A tosylate salt of Sorafenib which is a kinase inhibitor drug. It is used for the treatment of kidney, liver and thyroid cancer. It works by inhibiting the VEGFR-2/PDGFR-beta signaling cascade, thereby blocking tumor angiogenesis. Reference standards of Sorafenib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Sorafenib β-D-Glucuronide
    [catalogue_number] => PA 19 69540
    [category_ids] => ,70,71,75,79,80,82,89,95,
    [chemical_name] => 
    [weight] => 640.95
    [form] => C27H24ClF3N4O9
    [cas] => 1130164-93-0
    [pslug] => 1130164-93-0-sorafenib-beta-d-glucuronide-pa1969540
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PA 19 69540

Sorafenib β-D-Glucuronide

  • Catalogue No.:PA 19 69540

  • CAS :

    1130164-93-0

  • Molecular Formula : C27H24ClF3N4O9

  • Molecular Weight : 640.95

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Details 
stdClass Object
(
    [pname] => Sorafenib Hemi-Tosylate
    [catalogue_number] => PA 19 69550
    [category_ids] => 89,80,79,75,71,82,70
    [chemical_name] => 
    [weight] => 464.83
    [form] => C21H16ClF3N4O3 .1/2 C7H8O3S
    [cas] => 2056030-06-7
    [pslug] => 2056030-06-7-sorafenib-hemi-tosylate-pa1969550
    [latest_product] => 0
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PA 19 69550

Sorafenib Hemi-Tosylate

  • Catalogue No.:PA 19 69550

  • CAS :

    2056030-06-7

  • Molecular Formula : C21H16ClF3N4O3 .1/2 C7H8O3S

  • Molecular Weight : 464.83

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Details 
stdClass Object
(
    [pname] => 4-(Hydroxyamino)phenol
    [catalogue_number] => PA 46 0171000
    [category_ids] => ,75,76,78,82,
    [chemical_name] => 
    [weight] => 125.13
    [form] => C6H7NO2
    [cas] => 3505-87-1
    [pslug] => 3505-87-1-4-hydroxyamino-phenol-pa460171000
    [latest_product] => 0
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PA 46 0171000

4-(Hydroxyamino)phenol

  • Catalogue No.:PA 46 0171000

  • CAS :

    3505-87-1

  • Molecular Formula : C6H7NO2

  • Molecular Weight : 125.13

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Details 
stdClass Object
(
    [pname] => Sorafenib Hydroxydemethylamine
    [catalogue_number] => PA 46 0171001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 451.79
    [form] => C20H13ClF3N3O4
    [cas] => 1012058-78-4
    [pslug] => 1012058-78-4-sorafenib-hydroxydemethylamine-pa460171001
    [latest_product] => 0
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PA 46 0171001

Sorafenib Hydroxydemethylamine

  • Catalogue No.:PA 46 0171001

  • CAS :

    1012058-78-4

  • Molecular Formula : C20H13ClF3N3O4

  • Molecular Weight : 451.79

Enquire
Details 
stdClass Object
(
    [pname] => 4-(4-Aminophenoxy)picolinic acid
    [catalogue_number] => PA 46 0171002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 230.22
    [form] => C12H10N2O3
    [cas] => 1012058-77-3
    [pslug] => 1012058-77-3-4-4-aminophenoxy-picolinic-acid-pa460171002
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PA 46 0171002

4-(4-Aminophenoxy)picolinic acid

  • Catalogue No.:PA 46 0171002

  • CAS :

    1012058-77-3

  • Molecular Formula : C12H10N2O3

  • Molecular Weight : 230.22

Enquire
Details 
stdClass Object
(
    [pname] => 4-(3-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide
    [catalogue_number] => PA 19 0691000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 464.83
    [form] => C21H16ClF3N4O3
    [cas] => 284461-76-3
    [pslug] => 284461-76-3-4-3-3-4-chloro-3-trifluoromethyl-phenyl-ureido-phenoxy-n-methylpicolinamide-pa190691000
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PA 19 0691000

4-(3-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide

  • Catalogue No.:PA 19 0691000

  • CAS :

    284461-76-3

  • Molecular Formula : C21H16ClF3N4O3

  • Molecular Weight : 464.83

Enquire
Details 
stdClass Object
(
    [pname] => N-Desmethyl Sorafenib (Pyridine)-N-oxide
    [catalogue_number] => PA 19 0691001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 466.8
    [form] => C20H14ClF3N4O4
    [cas] => 583840-04-4
    [pslug] => 583840-04-4-n-desmethyl-sorafenib-pyridine-n-oxide-pa190691001
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PA 19 0691001

N-Desmethyl Sorafenib (Pyridine)-N-oxide

  • Catalogue No.:PA 19 0691001

  • CAS :

    583840-04-4

  • Molecular Formula : C20H14ClF3N4O4

  • Molecular Weight : 466.8

Enquire
Details 
stdClass Object
(
    [pname] => 1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea
    [catalogue_number] => PA 19 0691002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 330.69
    [form] => C14H10ClF3N2O2
    [cas] => 1129683-83-5
    [pslug] => 1129683-83-5-1-4-chloro-3-trifluoromethylphenyl-3-4-hydroxyphenyl-urea-pa190691002
    [latest_product] => 0
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PA 19 0691002

1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea

  • Catalogue No.:PA 19 0691002

  • CAS :

    1129683-83-5

  • Molecular Formula : C14H10ClF3N2O2

  • Molecular Weight : 330.69

Enquire
Details 
stdClass Object
(
    [pname] => 2-Chloro-1-isocyanato-3-(trifluoromethyl)benzene
    [catalogue_number] => PA 46 0171003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 221.56
    [form] => C8H3ClF3NO
    [cas] => 88330-63-6
    [pslug] => 88330-63-6-2-chloro-1-isocyanato-3-trifluoromethyl-benzene-pa460171003
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PA 46 0171003

2-Chloro-1-isocyanato-3-(trifluoromethyl)benzene

  • Catalogue No.:PA 46 0171003

  • CAS :

    88330-63-6

  • Molecular Formula : C8H3ClF3NO

  • Molecular Weight : 221.56

Enquire
Details 
stdClass Object
(
    [pname] => N-Methyl-4-phenoxypicolinamide
    [catalogue_number] => PA 46 0171004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 228.25
    [form] => C13H12N2O2
    [cas] => 2004659-85-0
    [pslug] => 2004659-85-0-n-methyl-4-phenoxypicolinamide-pa460171004
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PA 46 0171004

N-Methyl-4-phenoxypicolinamide

  • Catalogue No.:PA 46 0171004

  • CAS :

    2004659-85-0

  • Molecular Formula : C13H12N2O2

  • Molecular Weight : 228.25

Enquire
Details 
stdClass Object
(
    [pname] => Phenyl (4-chloro-3-(trifluoromethyl)phenyl)carbamate
    [catalogue_number] => PA 46 0171005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 315.68
    [form] => C14H9ClF3NO2
    [cas] => 871555-75-8
    [pslug] => 871555-75-8-phenyl-4-chloro-3-trifluoromethyl-phenyl-carbamate-pa460171005
    [latest_product] => 0
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PA 46 0171005

Phenyl (4-chloro-3-(trifluoromethyl)phenyl)carbamate

  • Catalogue No.:PA 46 0171005

  • CAS :

    871555-75-8

  • Molecular Formula : C14H9ClF3NO2

  • Molecular Weight : 315.68

Enquire
Details 
stdClass Object
(
    [pname] => 1-(4-Chloro-3-(trifluoromethyl)phenyl)urea
    [catalogue_number] => PA 46 0171006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 238.59
    [form] => C8H6ClF3N2O
    [cas] => 343247-69-8
    [pslug] => 343247-69-8-1-4-chloro-3-trifluoromethyl-phenyl-urea-pa460171006
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PA 46 0171006

1-(4-Chloro-3-(trifluoromethyl)phenyl)urea

  • Catalogue No.:PA 46 0171006

  • CAS :

    343247-69-8

  • Molecular Formula : C8H6ClF3N2O

  • Molecular Weight : 238.59

Enquire
Details 
stdClass Object
(
    [pname] => 6-Chloro-N-methyl-2-pyridinecarboxamide
    [catalogue_number] => PA 46 0171007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 170.6
    [form] => C7H7ClN2O
    [cas] => 845306-04-9
    [pslug] => 845306-04-9-6-chloro-n-methyl-2-pyridinecarboxamide-pa460171007
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PA 46 0171007

6-Chloro-N-methyl-2-pyridinecarboxamide

  • Catalogue No.:PA 46 0171007

  • CAS :

    845306-04-9

  • Molecular Formula : C7H7ClN2O

  • Molecular Weight : 170.6

Enquire
Details 
stdClass Object
(
    [pname] => N-Methylpicolinamide hydrochloride
    [catalogue_number] => PA 46 0171008
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 172.61
    [form] => C7H9ClN2O
    [cas] => NA
    [pslug] => n-methylpicolinamide-hydrochloride-pa460171008
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PA 46 0171008

N-Methylpicolinamide hydrochloride

  • Catalogue No.:PA 46 0171008

  • CAS :

    NA

  • Molecular Formula : C7H9ClN2O

  • Molecular Weight : 172.61

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Details 
stdClass Object
(
    [pname] => Phenyl (2-chloro-3-(trifluoromethyl)phenyl)carbamate
    [catalogue_number] => PAI 19 069001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 315.68
    [form] => C14H9ClF3NO2
    [cas] => 2518227-67-1
    [pslug] => 2518227-67-1-phenyl-2-chloro-3-trifluoromethyl-phenyl-carbamate-pai19069001
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PAI 19 069001

Phenyl (2-chloro-3-(trifluoromethyl)phenyl)carbamate

  • Catalogue No.:PAI 19 069001

  • CAS :

    2518227-67-1

  • Molecular Formula : C14H9ClF3NO2

  • Molecular Weight : 315.68

Enquire
Details 
stdClass Object
(
    [pname] => N-(2-Chloro-3-(trifluoromethyl)phenyl)-O-pivaloylhydroxylamine
    [catalogue_number] => PAI 19 069002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 295.69
    [form] => C12H13ClF3NO2
    [cas] => NA
    [pslug] => n-2-chloro-3-trifluoromethyl-phenyl-o-pivaloylhydroxylamine-pai19069002
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PAI 19 069002

N-(2-Chloro-3-(trifluoromethyl)phenyl)-O-pivaloylhydroxylamine

  • Catalogue No.:PAI 19 069002

  • CAS :

    NA

  • Molecular Formula : C12H13ClF3NO2

  • Molecular Weight : 295.69

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Details 
stdClass Object
(
    [pname] => Phenyl (4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamate
    [catalogue_number] => PAI 46 017001
    [category_ids] => 82,78,76,75,70
    [chemical_name] => 
    [weight] => 363.37
    [form] => C20H17N3O4
    [cas] => 1129683-92-6
    [pslug] => 1129683-92-6-phenyl-4-2-methylcarbamoyl-pyridin-4-yl-oxy-phenyl-carbamate-pai46017001
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PAI 46 017001

Phenyl (4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamate

  • Catalogue No.:PAI 46 017001

  • CAS :

    1129683-92-6

  • Molecular Formula : C20H17N3O4

  • Molecular Weight : 363.37

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Details 
stdClass Object
(
    [pname] => 4-(4-(3-(4-Chloro-3(trifluoromethyl)phenyl)ureido)phenox yl)-n-ethylpicolinamide
    [catalogue_number] => PA 46 0171010
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 478.86
    [form] => C22H18ClF3N4O3
    [cas] => 284461-82-1
    [pslug] => 284461-82-1-4-4-3-4-chloro-3-trifluoromethyl-phenyl-ureido-phenox-yl-n-ethylpicolinamide-pa460171010
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PA 46 0171010

4-(4-(3-(4-Chloro-3(trifluoromethyl)phenyl)ureido)phenox yl)-n-ethylpicolinamide

  • Catalogue No.:PA 46 0171010

  • CAS :

    284461-82-1

  • Molecular Formula : C22H18ClF3N4O3

  • Molecular Weight : 478.86

Enquire
Details 
stdClass Object
(
    [pname] => N-Methyl-4-(4-ureidophenoxy)picolinamide
    [catalogue_number] => PA 46 0171009
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 286.29
    [form] => C14H14N4O3
    [cas] => 1129683-88-0
    [pslug] => 1129683-88-0-n-methyl-4-4-ureidophenoxy-picolinamide-pa460171009
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PA 46 0171009

N-Methyl-4-(4-ureidophenoxy)picolinamide

  • Catalogue No.:PA 46 0171009

  • CAS :

    1129683-88-0

  • Molecular Formula : C14H14N4O3

  • Molecular Weight : 286.29

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CPHI INDIA- 28, 30 November