Risdiplam is an oral mRNA splicing modifier used in the treatment of spinal muscular atrophy (SMA). Reference standards of Risdiplam API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => tert-Butyl 7-(2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-4,7-diazaspiro[2.5]octane-4-carboxylate [catalogue_number] => PA 18 1411000 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 372.43 [form] => C19H24N4O4 [cas] => 2133298-72-1 [pslug] => 2133298-72-1-tert-butyl-7-2-hydroxy-4-oxo-4h-pyrido-1-2-a-pyrimidin-7-yl-4-7-diazaspiro-2-5-octane-4-carboxylate-pa181411000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 1411000
CAS :
Molecular Formula : C19H24N4O4
Molecular Weight : 372.43
stdClass Object ( [pname] => tert-Butyl 7-(4-oxo-2-(tosyloxy)-4H-pyrido[1,2-a]pyrimidin-7-yl)-4,7-diazaspiro[2.5]octane-4-carboxylate [catalogue_number] => PA 18 1411001 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 526.61 [form] => C26H30N4O6S [cas] => 2133298-73-2 [pslug] => 2133298-73-2-tert-butyl-7-4-oxo-2-tosyloxy-4h-pyrido-1-2-a-pyrimidin-7-yl-4-7-diazaspiro-2-5-octane-4-carboxylate-pa181411001 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 1411001
Molecular Formula : C26H30N4O6S
Molecular Weight : 526.61
stdClass Object ( [pname] => tert-Butyl 7-(2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-4,7-diazaspiro[2.5]octane-4-carboxylate [catalogue_number] => PA 18 1411002 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 501.59 [form] => C27H31N7O3 [cas] => 2133298-74-3 [pslug] => 2133298-74-3-tert-butyl-7-2-2-8-dimethylimidazo-1-2-b-pyridazin-6-yl-4-oxo-4h-pyrido-1-2-a-pyrimidin-7-yl-4-7-diazaspiro-2-5-octane-4-carboxylate-pa181411002 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 1411002
Molecular Formula : C27H31N7O3
Molecular Weight : 501.59
stdClass Object ( [pname] => 2-(2,8-Dimethylimidazo[1,2-b]pyridazin-6-yl)-7-fluoro-4H-pyrido[1,2-a]pyrimidin-4-one [catalogue_number] => PA 18 1411003 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 309.3 [form] => C16H12FN5O [cas] => 1825352-87-1 [pslug] => 1825352-87-1-2-2-8-dimethylimidazo-1-2-b-pyridazin-6-yl-7-fluoro-4h-pyrido-1-2-a-pyrimidin-4-one-pa181411003 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 1411003
Molecular Formula : C16H12FN5O
Molecular Weight : 309.3
stdClass Object ( [pname] => 2-(2,8-Dimethylimidazo[1,2-b]pyridazin-6-yl)-7-(4-hydroxy-4,7-diazaspiro[2.5]octan-7-yl)-4H-pyrido[1,2-a]pyrimidin-4-one [catalogue_number] => PA 18 1411004 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 417.47 [form] => C22H23N7O2 [cas] => 2250441-24-6 [pslug] => 2250441-24-6-2-2-8-dimethylimidazo-1-2-b-pyridazin-6-yl-7-4-hydroxy-4-7-diazaspiro-2-5-octan-7-yl-4h-pyrido-1-2-a-pyrimidin-4-one-pa181411004 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 1411004
Molecular Formula : C22H23N7O2
Molecular Weight : 417.47
stdClass Object ( [pname] => 2-(2,8-Dimethylimidazo[1,2-b]pyridazin-6-yl)-7-(4-nitroso-4,7-diazaspiro[2.5]octan-7-yl)-4H-pyrido[1,2-a]pyrimidin-4-one [catalogue_number] => PA 18 1411009 [category_ids] => ,70,75,76,78,82,162, [chemical_name] => [weight] => 430.47 [form] => C22H22N8O2 [cas] => NA [pslug] => 2-2-8-dimethylimidazo-1-2-b-pyridazin-6-yl-7-4-nitroso-4-7-diazaspiro-2-5-octan-7-yl-4h-pyrido-1-2-a-pyrimidin-4-one-pa181411009 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 1411009
Molecular Formula : C22H22N8O2
Molecular Weight : 430.47
stdClass Object ( [pname] => tert-Butyl 4-nitroso-4,7-diazaspiro[2.5]octane-7-carboxylate [catalogue_number] => PA 18 1411010 [category_ids] => ,70,75,76,78,82,162, [chemical_name] => [weight] => 241.29 [form] => C11H19N3O3 [cas] => NA [pslug] => tert-butyl-4-nitroso-4-7-diazaspiro-2-5-octane-7-carboxylate-pa181411010 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 1411010
Molecular Formula : C11H19N3O3
Molecular Weight : 241.29
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