Risdiplam

Impurities - Risdiplam is an oral mRNA splicing modifier used in the treatment of spinal muscular atrophy (SMA). Reference standards of Risdiplam API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => tert-Butyl 7-(2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-4,7-diazaspiro[2.5]octane-4-carboxylate
    [catalogue_number] => PA 18 1411000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 372.43
    [form] => C19H24N4O4
    [cas] => 2133298-72-1
    [pslug] => 2133298-72-1-tert-butyl-7-2-hydroxy-4-oxo-4h-pyrido-1-2-a-pyrimidin-7-yl-4-7-diazaspiro-2-5-octane-4-carboxylate-pa181411000
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PA 18 1411000
PA 18 1411000

tert-Butyl 7-(2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-4,7-diazaspiro[2.5]octane-4-carboxylate

  • Catalogue No.:PA 18 1411000

  • CAS :

    2133298-72-1

  • Molecular Formula : C19H24N4O4

  • Molecular Weight : 372.43

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stdClass Object
(
    [pname] => tert-Butyl 7-(4-oxo-2-(tosyloxy)-4H-pyrido[1,2-a]pyrimidin-7-yl)-4,7-diazaspiro[2.5]octane-4-carboxylate
    [catalogue_number] => PA 18 1411001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 526.61
    [form] => C26H30N4O6S
    [cas] => 2133298-73-2
    [pslug] => 2133298-73-2-tert-butyl-7-4-oxo-2-tosyloxy-4h-pyrido-1-2-a-pyrimidin-7-yl-4-7-diazaspiro-2-5-octane-4-carboxylate-pa181411001
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PA 18 1411001
PA 18 1411001

tert-Butyl 7-(4-oxo-2-(tosyloxy)-4H-pyrido[1,2-a]pyrimidin-7-yl)-4,7-diazaspiro[2.5]octane-4-carboxylate

  • Catalogue No.:PA 18 1411001

  • CAS :

    2133298-73-2

  • Molecular Formula : C26H30N4O6S

  • Molecular Weight : 526.61

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stdClass Object
(
    [pname] => tert-Butyl 7-(2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-4,7-diazaspiro[2.5]octane-4-carboxylate
    [catalogue_number] => PA 18 1411002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 501.59
    [form] => C27H31N7O3
    [cas] => 2133298-74-3
    [pslug] => 2133298-74-3-tert-butyl-7-2-2-8-dimethylimidazo-1-2-b-pyridazin-6-yl-4-oxo-4h-pyrido-1-2-a-pyrimidin-7-yl-4-7-diazaspiro-2-5-octane-4-carboxylate-pa181411002
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PA 18 1411002
PA 18 1411002

tert-Butyl 7-(2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-4,7-diazaspiro[2.5]octane-4-carboxylate

  • Catalogue No.:PA 18 1411002

  • CAS :

    2133298-74-3

  • Molecular Formula : C27H31N7O3

  • Molecular Weight : 501.59

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stdClass Object
(
    [pname] => 2-(2,8-Dimethylimidazo[1,2-b]pyridazin-6-yl)-7-fluoro-4H-pyrido[1,2-a]pyrimidin-4-one
    [catalogue_number] => PA 18 1411003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 309.3
    [form] => C16H12FN5O
    [cas] => 1825352-87-1
    [pslug] => 1825352-87-1-2-2-8-dimethylimidazo-1-2-b-pyridazin-6-yl-7-fluoro-4h-pyrido-1-2-a-pyrimidin-4-one-pa181411003
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PA 18 1411003
PA 18 1411003

2-(2,8-Dimethylimidazo[1,2-b]pyridazin-6-yl)-7-fluoro-4H-pyrido[1,2-a]pyrimidin-4-one

  • Catalogue No.:PA 18 1411003

  • CAS :

    1825352-87-1

  • Molecular Formula : C16H12FN5O

  • Molecular Weight : 309.3

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Details 
stdClass Object
(
    [pname] => 2-(2,8-Dimethylimidazo[1,2-b]pyridazin-6-yl)-7-(4-hydroxy-4,7-diazaspiro[2.5]octan-7-yl)-4H-pyrido[1,2-a]pyrimidin-4-one
    [catalogue_number] => PA 18 1411004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 417.47
    [form] => C22H23N7O2
    [cas] => 2250441-24-6
    [pslug] => 2250441-24-6-2-2-8-dimethylimidazo-1-2-b-pyridazin-6-yl-7-4-hydroxy-4-7-diazaspiro-2-5-octan-7-yl-4h-pyrido-1-2-a-pyrimidin-4-one-pa181411004
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PA 18 1411004
PA 18 1411004

2-(2,8-Dimethylimidazo[1,2-b]pyridazin-6-yl)-7-(4-hydroxy-4,7-diazaspiro[2.5]octan-7-yl)-4H-pyrido[1,2-a]pyrimidin-4-one

  • Catalogue No.:PA 18 1411004

  • CAS :

    2250441-24-6

  • Molecular Formula : C22H23N7O2

  • Molecular Weight : 417.47

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Details 
stdClass Object
(
    [pname] => 2-(2,8-Dimethylimidazo[1,2-b]pyridazin-6-yl)-7-(4-nitroso-4,7-diazaspiro[2.5]octan-7-yl)-4H-pyrido[1,2-a]pyrimidin-4-one
    [catalogue_number] => PA 18 1411009
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 430.47
    [form] => C22H22N8O2
    [cas] => NA
    [pslug] => 2-2-8-dimethylimidazo-1-2-b-pyridazin-6-yl-7-4-nitroso-4-7-diazaspiro-2-5-octan-7-yl-4h-pyrido-1-2-a-pyrimidin-4-one-pa181411009
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PA 18 1411009
PA 18 1411009

2-(2,8-Dimethylimidazo[1,2-b]pyridazin-6-yl)-7-(4-nitroso-4,7-diazaspiro[2.5]octan-7-yl)-4H-pyrido[1,2-a]pyrimidin-4-one

  • Catalogue No.:PA 18 1411009

  • CAS :

    NA

  • Molecular Formula : C22H22N8O2

  • Molecular Weight : 430.47

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Details 
stdClass Object
(
    [pname] => tert-Butyl 4-nitroso-4,7-diazaspiro[2.5]octane-7-carboxylate
    [catalogue_number] => PA 18 1411010
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 241.29
    [form] => C11H19N3O3
    [cas] => NA
    [pslug] => tert-butyl-4-nitroso-4-7-diazaspiro-2-5-octane-7-carboxylate-pa181411010
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PA 18 1411010
PA 18 1411010

tert-Butyl 4-nitroso-4,7-diazaspiro[2.5]octane-7-carboxylate

  • Catalogue No.:PA 18 1411010

  • CAS :

    NA

  • Molecular Formula : C11H19N3O3

  • Molecular Weight : 241.29

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