Ledipasvir-impurities | Pharmaffiliates

ledipasvir

Ledipasvir is most commonly used in combination with sofosbuvir for treatment in chronic hepatitis C genotype 1 patients. Reference standards of Ledipasvir API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => tert-Butyl (1R,3R,4S)-3-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylate
    [catalogue_number] => PA 12 77510
    [category_ids] => ,90,79,75,
    [chemical_name] => 
    [weight] => 439.36
    [form] => C24H34BN3O4
    [cas] => NA
    [pslug] => tert-butyl-1r-3r-4s-3-6-4-4-5-5-tetramethyl-1-3-2-dioxaborolan-2-yl-1h-benzo-d-imidazol-2-yl-2-azabicyclo-2-2-1-heptane-2-carboxylate-pa1277510
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PA 12 77510

tert-Butyl (1R,3R,4S)-3-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylate


  • Catalogue No.:PA 12 77510

  • CAS :

    NA

  • Molecular Formula : C24H34BN3O4

  • Molecular Weight : 439.36

stdClass Object
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    [pname] => tert-Butyl (1S,3S,4R)-3-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylate
    [catalogue_number] => PA 12 77520
    [category_ids] => ,90,79,75,
    [chemical_name] => 
    [weight] => 439.36
    [form] => C24H34BN3O4
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    [pslug] => tert-butyl-1s-3s-4r-3-6-4-4-5-5-tetramethyl-1-3-2-dioxaborolan-2-yl-1h-benzo-d-imidazol-2-yl-2-azabicyclo-2-2-1-heptane-2-carboxylate-pa1277520
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PA 12 77520

tert-Butyl (1S,3S,4R)-3-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylate


  • Catalogue No.:PA 12 77520

  • CAS :

    NA

  • Molecular Formula : C24H34BN3O4

  • Molecular Weight : 439.36

stdClass Object
(
    [pname] => Methyl ((R)-1-((S)-6-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-L-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazol-6-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptan-5-yl)-3-methyl-1-oxobutan-2-yl)carbamate
    [catalogue_number] => PA 12 0771000
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 889
    [form] => C49H54F2N8O6
    [cas] => 1256393-35-7
    [pslug] => 1256393-35-7-methyl-r-1-s-6-5-9-9-difluoro-7-2-1r-3s-4s-2-methoxycarbonyl-l-valyl-2-azabicyclo-2-2-1-heptan-3-yl-1h-benzo-d-imidazol-6-yl-9h-fluoren-2-yl-1h-imidazol-2-yl-5-azaspiro-2-4-heptan-5-yl-3-methyl-1-oxobutan-2-yl-carbamate-pa120771000
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PA 12 0771000

Methyl ((R)-1-((S)-6-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-L-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazol-6-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptan-5-yl)-3-methyl-1-oxobutan-2-yl)carbamate


  • Catalogue No.:PA 12 0771000

  • CAS :

    1256393-35-7

  • Molecular Formula : C49H54F2N8O6

  • Molecular Weight : 889

stdClass Object
(
    [pname] => Methyl ((S)-1-((S)-6-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-D-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazol-6-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptan-5-yl)-3-methyl-1-oxobutan-2-yl)carbamate
    [catalogue_number] => PA 12 0771001
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 889
    [form] => C49H54F2N8O6
    [cas] => 1256391-66-8
    [pslug] => 1256391-66-8-methyl-s-1-s-6-5-9-9-difluoro-7-2-1r-3s-4s-2-methoxycarbonyl-d-valyl-2-azabicyclo-2-2-1-heptan-3-yl-1h-benzo-d-imidazol-6-yl-9h-fluoren-2-yl-1h-imidazol-2-yl-5-azaspiro-2-4-heptan-5-yl-3-methyl-1-oxobutan-2-yl-carbamate-pa120771001
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PA 12 0771001

Methyl ((S)-1-((S)-6-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-D-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazol-6-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptan-5-yl)-3-methyl-1-oxobutan-2-yl)carbamate


  • Catalogue No.:PA 12 0771001

  • CAS :

    1256391-66-8

  • Molecular Formula : C49H54F2N8O6

  • Molecular Weight : 889

stdClass Object
(
    [pname] => Ledipasvir 1S,3R,4R-Diastereomer
    [catalogue_number] => PA 12 0771002
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 889
    [form] => C49H54F2N8O6
    [cas] => NA
    [pslug] => ledipasvir-1s-3r-4r-diastereomer-pa120771002
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PA 12 0771002

Ledipasvir 1S,3R,4R-Diastereomer


  • Catalogue No.:PA 12 0771002

  • CAS :

    NA

  • Molecular Formula : C49H54F2N8O6

  • Molecular Weight : 889

stdClass Object
(
    [pname] => Ledipasvir 1S,3S,4R-Diastereomer
    [catalogue_number] => PA 12 0771003
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 889
    [form] => C49H54F2N8O6
    [cas] => NA
    [pslug] => ledipasvir-1s-3s-4r-diastereomer-pa120771003
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PA 12 0771003

Ledipasvir 1S,3S,4R-Diastereomer


  • Catalogue No.:PA 12 0771003

  • CAS :

    NA

  • Molecular Formula : C49H54F2N8O6

  • Molecular Weight : 889

stdClass Object
(
    [pname] => (S)-5-(tert-Butoxycarbonyl)-5-azaspiro[2.4]heptane-6-carboxylic Acid;
    [catalogue_number] => PA 12 0771004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 241.29
    [form] => C12H19NO4
    [cas] => 1129634-44-1
    [pslug] => 1129634-44-1-s-5-tert-butoxycarbonyl-5-azaspiro-2-4-heptane-6-carboxylic-acid-pa120771004
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PA 12 0771004

(S)-5-(tert-Butoxycarbonyl)-5-azaspiro[2.4]heptane-6-carboxylic Acid;


  • Catalogue No.:PA 12 0771004

  • CAS :

    1129634-44-1

  • Molecular Formula : C12H19NO4

  • Molecular Weight : 241.29

stdClass Object
(
    [pname] => Ledipasvir D8
    [catalogue_number] => PA STI 089132
    [category_ids] => ,98,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 897.07
    [form] => C49H46D8F2N8O6
    [cas] => NA
    [pslug] => ledipasvir-d8-pasti089132
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PA STI 089132

Ledipasvir D8


  • Catalogue No.:PA STI 089132

  • CAS :

    NA

  • Molecular Formula : C49H46D8F2N8O6

  • Molecular Weight : 897.07