etoricoxib
A COX-2 inhibitor, Etoricoxib is used in the treatment of rheumatoid arthritis, psoriatic arthritis, osteoarthritis, spondylitis, chronic low back pain, and gout. It is a selective inhibitor of isoform 2 of the enzyme cyclooxygenase. Reference standards of Etoricoxib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
(
[pname] => 2-Chloro-3-(dimethylamino)-N,N-dimethyl-2-propen-1-aminium Hexafluorophosphate(1-)
[catalogue_number] => PA 05 40510
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[weight] => 306.62
[form] => C7H14ClF6N2P
[cas] => 291756-76-8
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2-Chloro-3-(dimethylamino)-N,N-dimethyl-2-propen-1-aminium Hexafluorophosphate(1-)
Catalogue No.:PA 05 40510
Molecular Formula : C7H14ClF6N2P
Molecular Weight : 306.62
stdClass Object
(
[pname] => 2-(4-Methanesulfonyl-phenyl)-1-(6-methyl-pyridin-3-yl)-ethanone
[catalogue_number] => PA 05 40540
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[chemical_name] =>
[weight] => 289.35
[form] => C15H15NO3S
[cas] => 221615-75-4
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2-(4-Methanesulfonyl-phenyl)-1-(6-methyl-pyridin-3-yl)-ethanone
Catalogue No.:PA 05 40540
Molecular Formula : C15H15NO3S
Molecular Weight : 289.35
stdClass Object
(
[pname] => 6'-Desmethyl-6'-methylhydroxy Etoricoxib
[catalogue_number] => PA 05 40560
[category_ids] => ,79,80,71,76,75,78,70,82,88,
[chemical_name] =>
[weight] => 374.84
[form] => C18H15ClN2O3S
[cas] => 349536-41-0
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6'-Desmethyl-6'-methylhydroxy Etoricoxib
Catalogue No.:PA 05 40560
Molecular Formula : C18H15ClN2O3S
Molecular Weight : 374.84
stdClass Object
(
[pname] => 6'-Desmethyl-6'-carboxy Etoricoxib
[catalogue_number] => PA 05 40590
[category_ids] => ,79,80,71,76,75,78,70,82,88,
[chemical_name] =>
[weight] => 388.82
[form] => C18H13ClN2O4S
[cas] => 349536-39-6
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6'-Desmethyl-6'-carboxy Etoricoxib
Catalogue No.:PA 05 40590
Molecular Formula : C18H13ClN2O4S
Molecular Weight : 388.82
stdClass Object
(
[pname] => Etoricoxib N1'-Oxide
[catalogue_number] => PA 05 40600
[category_ids] => ,80,71,75,78,70,82,88,
[chemical_name] =>
[weight] => 374.84
[form] => C18H15ClN2O3S
[cas] => 325855-74-1
[pslug] => 325855-74-1-etoricoxib-n1-oxide-pa0540600
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Catalogue No.:PA 05 40600
Molecular Formula : C18H15ClN2O3S
Molecular Weight : 374.84
stdClass Object
(
[pname] => 5,14-Dehydro Etoricoxib
[catalogue_number] => PA 05 0401000
[category_ids] => ,84,78,70,82,75,76,
[chemical_name] =>
[weight] => 356.82
[form] => C18H13ClN2O2S
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Catalogue No.:PA 05 0401000
Molecular Formula : C18H13ClN2O2S
Molecular Weight : 356.82
stdClass Object
(
[pname] => 2-(4-(Methylthio)phenyl)-1-(pyridin-3-yl)ethan-1-one
[catalogue_number] => PAI 05 002511
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[chemical_name] =>
[weight] => 243.32
[form] => C14H13NOS
[cas] => 40061-49-2
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2-(4-(Methylthio)phenyl)-1-(pyridin-3-yl)ethan-1-one
Catalogue No.:PAI 05 002511
Molecular Formula : C14H13NOS
Molecular Weight : 243.32
stdClass Object
(
[pname] => 5-Chloro-3-(4-(methylthio)phenyl)-2,3'-bipyridine
[catalogue_number] => PAI 05 002512
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[weight] => 312.82
[form] => C17H13ClN2S
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5-Chloro-3-(4-(methylthio)phenyl)-2,3'-bipyridine
Catalogue No.:PAI 05 002512
Molecular Formula : C17H13ClN2S
Molecular Weight : 312.82
stdClass Object
(
[pname] => Ethyl (4-methylthiophenyl)acetate
[catalogue_number] => PAI 05 002513
[category_ids] => ,78,75,70,76,82,
[chemical_name] =>
[weight] => 210.29
[form] => C11H14O2S
[cas] => 14062-27-2
[pslug] => 14062-27-2-ethyl-4-methylthiophenyl-acetate-pai05002513
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Ethyl (4-methylthiophenyl)acetate
Catalogue No.:PAI 05 002513
Molecular Formula : C11H14O2S
Molecular Weight : 210.29
stdClass Object
(
[pname] => 1-(6-Methylpyridin-3-yl)-2-(4-(methylsulfinyl)phenyl)ethan-1-one
[catalogue_number] => PA 05 0401001
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[weight] => 273.35
[form] => C15H15NO2S
[cas] => 307531-95-9
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1-(6-Methylpyridin-3-yl)-2-(4-(methylsulfinyl)phenyl)ethan-1-one
Catalogue No.:PA 05 0401001
Molecular Formula : C15H15NO2S
Molecular Weight : 273.35
stdClass Object
(
[pname] => 1-(6-Methylpyridin-3-yl)-2-(4-(methylthio)phenyl)ethan-1-one
[catalogue_number] => PA 05 0401002
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[weight] => 257.35
[form] => C15H15NOS
[cas] => 221615-72-1
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1-(6-Methylpyridin-3-yl)-2-(4-(methylthio)phenyl)ethan-1-one
Catalogue No.:PA 05 0401002
Molecular Formula : C15H15NOS
Molecular Weight : 257.35
stdClass Object
(
[pname] => 1-(6-Methylpyridin-3-yl)-2-((4-(2-(6-methylpyridin-3-yl)-2-oxoethyl)phenyl)sulfonyl)ethan-1-one
[catalogue_number] => PA 05 0401003
[category_ids] => ,78,75,70,76,82,
[chemical_name] =>
[weight] => 408.47
[form] => C22H20N2O4S
[cas] => 1421227-97-5
[pslug] => 1421227-97-5-1-6-methylpyridin-3-yl-2-4-2-6-methylpyridin-3-yl-2-oxoethyl-phenyl-sulfonyl-ethan-1-one-pa050401003
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1-(6-Methylpyridin-3-yl)-2-((4-(2-(6-methylpyridin-3-yl)-2-oxoethyl)phenyl)sulfonyl)ethan-1-one
Catalogue No.:PA 05 0401003
Molecular Formula : C22H20N2O4S
Molecular Weight : 408.47
stdClass Object
(
[pname] => Etoricoxib D4
[catalogue_number] => PA STI 088697
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 362.86
[form] => C18H11D4ClN2O2S
[cas] => 1131345-14-6
[pslug] => 1131345-14-6-etoricoxib-d4-pasti088697
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Catalogue No.:PA STI 088697
Molecular Formula : C18H11D4ClN2O2S
Molecular Weight : 362.86
stdClass Object
(
[pname] => 6'-Methyl-3-(4-(methylsulfonyl)phenyl)-2,3'-bipyridine
[catalogue_number] => PA 05 0401004
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[chemical_name] =>
[weight] => 324.4
[form] => C18H16N2O2S
[cas] => 1350206-14-2
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6'-Methyl-3-(4-(methylsulfonyl)phenyl)-2,3'-bipyridine
stdClass Object
(
[pname] => 6,6''-Dimethyl-3',5'-bis(4-(methylsulfonyl)phenyl)-3,2':6',3''-terpyridine;
[catalogue_number] => PA 05 0401005
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[chemical_name] =>
[weight] => 569.69
[form] => C31H27N3O4S2
[cas] => NA
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6,6''-Dimethyl-3',5'-bis(4-(methylsulfonyl)phenyl)-3,2':6',3''-terpyridine;
Catalogue No.:PA 05 0401005
Molecular Formula : C31H27N3O4S2
Molecular Weight : 569.69
stdClass Object
(
[pname] => 2-(4-(Methylsulfonyl)phenyl)-1-morpholinoethan-1-one
[catalogue_number] => PA 05 0401006
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 283.34
[form] => C13H17NO4S
[cas] => 1798110-01-6
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2-(4-(Methylsulfonyl)phenyl)-1-morpholinoethan-1-one
Catalogue No.:PA 05 0401006
Molecular Formula : C13H17NO4S
Molecular Weight : 283.34
stdClass Object
(
[pname] => 2-Methyl-5-(2-(4-(methylsulfonyl)phenyl)acetyl)pyridine 1-oxide
[catalogue_number] => PA 05 0401007
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 305.35
[form] => C15H15NO4S
[cas] => 1027162-35-1
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2-Methyl-5-(2-(4-(methylsulfonyl)phenyl)acetyl)pyridine 1-oxide
Catalogue No.:PA 05 0401007
Molecular Formula : C15H15NO4S
Molecular Weight : 305.35
stdClass Object
(
[pname] => (E)-5-(1,3-bis(4-(Methylsulfonyl)phenyl)prop-1-en-2-yl)-2-methylpyridine
[catalogue_number] => PA 05 0401008
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[chemical_name] =>
[weight] => 441.56
[form] => C23H23NO4S2
[cas] => NA
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(E)-5-(1,3-bis(4-(Methylsulfonyl)phenyl)prop-1-en-2-yl)-2-methylpyridine
Catalogue No.:PA 05 0401008
Molecular Formula : C23H23NO4S2
Molecular Weight : 441.56
stdClass Object
(
[pname] => 4-Chloro-5-(dimethylamino)-1-(6-methylpyridin-3-yl)-2-(4-(methylsulfonyl)phenyl)penta-2,4-dien-1-one
[catalogue_number] => PA 05 0401009
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[chemical_name] =>
[weight] => 404.91
[form] => C20H21ClN2O3S
[cas] => 2373365-28-5
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4-Chloro-5-(dimethylamino)-1-(6-methylpyridin-3-yl)-2-(4-(methylsulfonyl)phenyl)penta-2,4-dien-1-one
Catalogue No.:PA 05 0401009
Molecular Formula : C20H21ClN2O3S
Molecular Weight : 404.91
stdClass Object
(
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[catalogue_number] => PA 05 0401010
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[chemical_name] =>
[weight] => 326.84
[form] => C18H15ClN2S
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5-Chloro-6'-methyl-3-(4-(methylthio)phenyl)-2,3'-bipyridine
Catalogue No.:PA 05 0401010
Molecular Formula : C18H15ClN2S
Molecular Weight : 326.84
stdClass Object
(
[pname] => 2-((4-(5-Chloro-6'-methyl-[2,3'-bipyridin]-3-yl)phenyl)sulfonyl)-1-(6-methylpyridin-3-yl)ethan-1-one
[catalogue_number] => PA 05 0401011
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[chemical_name] =>
[weight] => 477.96
[form] => C25H20ClN3O3S
[cas] => 1817735-82-2
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2-((4-(5-Chloro-6'-methyl-[2,3'-bipyridin]-3-yl)phenyl)sulfonyl)-1-(6-methylpyridin-3-yl)ethan-1-one
Catalogue No.:PA 05 0401011
Molecular Formula : C25H20ClN3O3S
Molecular Weight : 477.96
stdClass Object
(
[pname] => 1-(6-Methylpyridin-3-yl)-2-(2-(methylsulfonyl)phenyl)ethan-1-one
[catalogue_number] => PA 05 0401022
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[chemical_name] =>
[weight] => 289.35
[form] => C15H15NO3S
[cas] => NA
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1-(6-Methylpyridin-3-yl)-2-(2-(methylsulfonyl)phenyl)ethan-1-one
Catalogue No.:PA 05 0401022
Molecular Formula : C15H15NO3S
Molecular Weight : 289.35
stdClass Object
(
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[catalogue_number] => PA 05 0401023
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[chemical_name] =>
[weight] => 182.24
[form] => C9H10O2S
[cas] => 32361-73-2
[pslug] => 32361-73-2-1-4-methylsulfinyl-phenyl-ethan-1-one-pa050401023
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1-(4-(Methylsulfinyl)phenyl)ethan-1-one
Catalogue No.:PA 05 0401023
Molecular Formula : C9H10O2S
Molecular Weight : 182.24
stdClass Object
(
[pname] => 2-(4-(Methylsulfonyl)phenyl)-1-morpholinoethane-1-thione
[catalogue_number] => PA 05 0401024
[category_ids] => ,76,75,78,70,82,
[chemical_name] =>
[weight] => 299.4
[form] => C13H17NO3S2
[cas] => 859824-65-0
[pslug] => 859824-65-0-2-4-methylsulfonyl-phenyl-1-morpholinoethane-1-thione-pa050401024
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2-(4-(Methylsulfonyl)phenyl)-1-morpholinoethane-1-thione
stdClass Object
(
[pname] => 3-Hydroxy-3-(6-methylpyridin-3-yl)-2,4-bis(4-(methylsulfonyl)phenyl)butanoic Acid
[catalogue_number] => PA 05 0401025
[category_ids] => ,76,75,78,70,82,
[chemical_name] =>
[weight] => 503.58
[form] => C24H25NO7S2
[cas] => NA
[pslug] => 3-hydroxy-3-6-methylpyridin-3-yl-2-4-bis-4-methylsulfonyl-phenyl-butanoic-acid-pa050401025
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3-Hydroxy-3-(6-methylpyridin-3-yl)-2,4-bis(4-(methylsulfonyl)phenyl)butanoic Acid
Catalogue No.:PA 05 0401025
Molecular Formula : C24H25NO7S2
Molecular Weight : 503.58
