Elexacaftor
Elexacaftor is a small molecule CFTR corrector used in combination with tezacaftor and ivacaftor for the treatment of cystic fibrosis patients with one F508del-CFTR mutation. Reference standards of Elexacaftor API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
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[pname] => Elexacaftor
[catalogue_number] => PA 05 1861000
[category_ids] => ,82,78,76,75,70,
[chemical_name] =>
[weight] => 597.66
[form] => C26H34F3N7O4S
[cas] => 2216712-66-0
[pslug] => 2216712-66-0-elexacaftor-api-pa051861000
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Catalogue No.:PA 05 1861000
Molecular Formula : C26H34F3N7O4S
Molecular Weight : 597.66
stdClass Object
(
[pname] => 2-Chloro-N-((1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl)-6-(3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl)nicotinamide
[catalogue_number] => PA 05 1861001
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 520.91
[form] => C19H20ClF3N6O4S
[cas] => 2229861-18-9
[pslug] => 2229861-18-9-2-chloro-n-1-3-dimethyl-1h-pyrazol-4-yl-sulfonyl-6-3-3-3-3-trifluoro-2-2-dimethylpropoxy-1h-pyrazol-1-yl-nicotinamide-pa051861001
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2-Chloro-N-((1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl)-6-(3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl)nicotinamide
Catalogue No.:PA 05 1861001
Molecular Formula : C19H20ClF3N6O4S
Molecular Weight : 520.91
stdClass Object
(
[pname] => N-Desmethyl Elexacaftor
[catalogue_number] => PA 05 1861002
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 583.63
[form] => C25H32F3N7O4S
[cas] => 2229860-93-7
[pslug] => 2229860-93-7-n-desmethyl-elexacaftor-pa051861002
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Catalogue No.:PA 05 1861002
Molecular Formula : C25H32F3N7O4S
Molecular Weight : 583.63
stdClass Object
(
[pname] => (R)-Elexacaftor
[catalogue_number] => PA 05 1861003
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 597.66
[form] => C26H34F3N7O4S
[cas] => 2229860-99-3
[pslug] => 2229860-99-3-r-elexacaftor-pa051861003
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Catalogue No.:PA 05 1861003
Molecular Formula : C26H34F3N7O4S
Molecular Weight : 597.66
