Alprazolam

Alprazolam is mostly used in short term management of anxiety disorders, panic disorders, and nausea due to chemotherapy. It is sold under the trade name Xanax, among others, is a short-acting benzodiazepine. Reference standards of Alprazolam API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => (2-(3-(Aminomethyl)-5-methyl-4H-1,2,4-triazol-4-yl)-5-chlorophenyl)(phenyl)methanone methanesulfonate
    [catalogue_number] => PA 01 0401000
    [category_ids] => ,82,80,79,78,75,71,70,165,
    [chemical_name] => 
    [weight] => 422.88
    [form] => C18H19ClN4O4S
    [cas] => NA
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PA 01 0401000

(2-(3-(Aminomethyl)-5-methyl-4H-1,2,4-triazol-4-yl)-5-chlorophenyl)(phenyl)methanone methanesulfonate


  • Catalogue No.:PA 01 0401000

  • CAS :

    NA

  • Molecular Formula : C18H19ClN4O4S

  • Molecular Weight : 422.88

stdClass Object
(
    [pname] => 1-Hydroxy Alprazolam β-D-Glucuronide
    [catalogue_number] => PA 01 0401001
    [category_ids] => ,95,82,78,76,75,70,165,
    [chemical_name] => 
    [weight] => 500.89
    [form] => C23H21ClN4O7
    [cas] => 144964-58-9
    [pslug] => 144964-58-9-1-hydroxy-alprazolam-beta-d-glucuronide-pa010401001
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PA 01 0401001

1-Hydroxy Alprazolam β-D-Glucuronide


  • Catalogue No.:PA 01 0401001

  • CAS :

    144964-58-9

  • Molecular Formula : C23H21ClN4O7

  • Molecular Weight : 500.89

stdClass Object
(
    [pname] => 4-Acetoxy alprazolam
    [catalogue_number] => PA 01 0401002
    [category_ids] => ,82,78,76,75,70,165,
    [chemical_name] => 
    [weight] => 366.81
    [form] => C19H15ClN4O2
    [cas] => 30896-67-4
    [pslug] => 30896-67-4-4-acetoxy-alprazolam-pa010401002
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PA 01 0401002

4-Acetoxy alprazolam


  • Catalogue No.:PA 01 0401002

  • CAS :

    30896-67-4

  • Molecular Formula : C19H15ClN4O2

  • Molecular Weight : 366.81

stdClass Object
(
    [pname] => N,N-Bis((4-(2-benzoyl-4-chlorophenyl)-5-methyl-4H-1,2,4-triazol-3-yl)methyl)nitrous Amide
    [catalogue_number] => PA 01 0401004
    [category_ids] => ,82,80,79,78,75,71,70,165,
    [chemical_name] => 
    [weight] => 665.54
    [form] => C34H26Cl2N8O3
    [cas] => NA
    [pslug] => n-n-bis-4-2-benzoyl-4-chlorophenyl-5-methyl-4h-1-2-4-triazol-3-yl-methyl-nitrous-amide-pa010401004
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PA 01 0401004

N,N-Bis((4-(2-benzoyl-4-chlorophenyl)-5-methyl-4H-1,2,4-triazol-3-yl)methyl)nitrous Amide


  • Catalogue No.:PA 01 0401004

  • CAS :

    NA

  • Molecular Formula : C34H26Cl2N8O3

  • Molecular Weight : 665.54

stdClass Object
(
    [pname] => Alprazolam - Impurity A
    [catalogue_number] => PA 01 40010
    [category_ids] => ,82,80,79,78,75,71,70,165,
    [chemical_name] => 
    [weight] => 287.74
    [form] => C15H14ClN3O
    [cas] => 27537-87-7
    [pslug] => 27537-87-7-alprazolam-impurity-a-pa0140010
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PA 01 40010

Alprazolam - Impurity A


  • Catalogue No.:PA 01 40010

  • CAS :

    27537-87-7

  • Molecular Formula : C15H14ClN3O

  • Molecular Weight : 287.74

stdClass Object
(
    [pname] => Alprazolam - Impurity C
    [catalogue_number] => PA 01 40030
    [category_ids] => ,82,80,78,75,71,70,165,
    [chemical_name] => 
    [weight] => 297.74
    [form] => C16H12ClN3O
    [cas] => 36916-19-5
    [pslug] => 36916-19-5-alprazolam-impurity-c-pa0140030
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PA 01 40030

Alprazolam - Impurity C


  • Catalogue No.:PA 01 40030

  • CAS :

    36916-19-5

  • Molecular Formula : C16H12ClN3O

  • Molecular Weight : 297.74

stdClass Object
(
    [pname] => Alprazolam - Impurity E
    [catalogue_number] => PA 01 40050
    [category_ids] => 165,82,78,76,75,70
    [chemical_name] => 
    [weight] => 231.68
    [form] => C13H10ClNO
    [cas] => 719-59-5
    [pslug] => 719-59-5-alprazolam-impurity-e-freebase-pa0140050
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PA 01 40050

Alprazolam - Impurity E


  • Catalogue No.:PA 01 40050

  • CAS :

    719-59-5

  • Molecular Formula : C13H10ClNO

  • Molecular Weight : 231.68

stdClass Object
(
    [pname] => Alprazolam - Impurity G
    [catalogue_number] => PA 01 40070
    [category_ids] => ,82,80,79,78,75,71,70,165,
    [chemical_name] => 
    [weight] => 308.76
    [form] => C17H13ClN4
    [cas] => 448950-89-8
    [pslug] => 448950-89-8-alprazolam-impurity-g-pa0140070
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PA 01 40070

Alprazolam - Impurity G


  • Catalogue No.:PA 01 40070

  • CAS :

    448950-89-8

  • Molecular Formula : C17H13ClN4

  • Molecular Weight : 308.76

stdClass Object
(
    [pname] => [2-[3-(Aminomethyl)-5-methyl-4H-1,2,4-triazol-4-yl]-5-chlorophenyl]phenylmethanone
    [catalogue_number] => PA 01 40510
    [category_ids] => ,82,80,79,78,75,71,70,165,
    [chemical_name] => 
    [weight] => 326.78
    [form] => C17H15ClN4O
    [cas] => 125316-83-8
    [pslug] => 125316-83-8-2-3-aminomethyl-5-methyl-4h-1-2-4-triazol-4-yl-5-chlorophenyl-phenylmethanone-pa0140510
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PA 01 40510

[2-[3-(Aminomethyl)-5-methyl-4H-1,2,4-triazol-4-yl]-5-chlorophenyl]phenylmethanone


  • Catalogue No.:PA 01 40510

  • CAS :

    125316-83-8

  • Molecular Formula : C17H15ClN4O

  • Molecular Weight : 326.78

stdClass Object
(
    [pname] => 1-Methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
    [catalogue_number] => PA 01 40520
    [category_ids] => ,82,80,79,78,75,71,70,165,
    [chemical_name] => 
    [weight] => 274.32
    [form] => C17H14N4
    [cas] => 28910-92-1
    [pslug] => 28910-92-1-1-methyl-6-phenyl-4h-1-2-4-triazolo-4-3-a-1-4-benzodiazepine-pa0140520
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PA 01 40520

1-Methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine


  • Catalogue No.:PA 01 40520

  • CAS :

    28910-92-1

  • Molecular Formula : C17H14N4

  • Molecular Weight : 274.32

stdClass Object
(
    [pname] => 3-Amino-6-chloro-4-(4-pyridinyl)-2-quinolinone Hydrazone
    [catalogue_number] => PA 01 40550
    [category_ids] => ,82,80,79,78,75,71,70,165,
    [chemical_name] => 
    [weight] => 284.74
    [form] => C14H12ClN5
    [cas] => 1346606-48-1
    [pslug] => 1346606-48-1-3-amino-6-chloro-4-4-pyridinyl-2-quinolinone-hydrazone-pa0140550
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PA 01 40550

3-Amino-6-chloro-4-(4-pyridinyl)-2-quinolinone Hydrazone


  • Catalogue No.:PA 01 40550

  • CAS :

    1346606-48-1

  • Molecular Formula : C14H12ClN5

  • Molecular Weight : 284.74

stdClass Object
(
    [pname] => (5-Chloro-2-iodophenyl)(phenyl)methanone
    [catalogue_number] => PAI 01 040001
    [category_ids] => ,165,82,78,76,75,70,
    [chemical_name] => 
    [weight] => 342.56
    [form] => C13H8ClIO
    [cas] => 76049-48-4
    [pslug] => 76049-48-4-5-chloro-2-iodophenyl-phenyl-methanone-pai01040001
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PAI 01 040001

(5-Chloro-2-iodophenyl)(phenyl)methanone


  • Catalogue No.:PAI 01 040001

  • CAS :

    76049-48-4

  • Molecular Formula : C13H8ClIO

  • Molecular Weight : 342.56

stdClass Object
(
    [pname] => Alprazolam - Impurity B
    [catalogue_number] => PA 01 0400020
    [category_ids] => ,82,80,79,78,75,71,70,165,
    [chemical_name] => 
    [weight] => 327.77
    [form] => C17H14ClN3O2
    [cas] => 38150-27-5
    [pslug] => 38150-27-5-alprazolam-impurity-b-pa010400020
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PA 01 0400020

Alprazolam - Impurity B


  • Catalogue No.:PA 01 0400020

  • CAS :

    38150-27-5

  • Molecular Formula : C17H14ClN3O2

  • Molecular Weight : 327.77

stdClass Object
(
    [pname] => Alprazolam - Impurity D
    [catalogue_number] => PA 01 0400040
    [category_ids] => ,82,80,79,78,75,71,70,165,
    [chemical_name] => 
    [weight] => 320.78
    [form] => C18H13ClN4
    [cas] => NA
    [pslug] => alprazolam-impurity-d-pa010400040
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PA 01 0400040

Alprazolam - Impurity D


  • Catalogue No.:PA 01 0400040

  • CAS :

    NA

  • Molecular Formula : C18H13ClN4

  • Molecular Weight : 320.78

stdClass Object
(
    [pname] => Alprazolam - Impurity F
    [catalogue_number] => PA 01 0400060
    [category_ids] => ,82,80,79,78,75,71,70,165,
    [chemical_name] => 
    [weight] => 346.21
    [form] => C17H13Cl2N3O
    [cas] => 37945-07-6
    [pslug] => 37945-07-6-alprazolam-impurity-f-pa010400060
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PA 01 0400060

Alprazolam - Impurity F


  • Catalogue No.:PA 01 0400060

  • CAS :

    37945-07-6

  • Molecular Formula : C17H13Cl2N3O

  • Molecular Weight : 346.21

CPHI INDIA- 28, 30 November