agomelatine

Impurities - Agomelatine is an antidepressant that acts on melatonin receptors. It acts on brain receptors for melatonin, a hormone that is important for regulating sleep, as well as serotonin receptors. Reference standards of Agomelatine API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Agomelatine Dimer Acetamide
    [catalogue_number] => PA 01 31510
    [category_ids] => ,79,80,75,78,70,82,
    [chemical_name] => 
    [weight] => 427.53
    [form] => C28H29NO3
    [cas] => 1385018-58-5
    [pslug] => 1385018-58-5-agomelatine-dimer-acetamide-pa0131510
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PA 01 31510
PA 01 31510

Agomelatine Dimer Acetamide


  • Catalogue No.:PA 01 31510

  • CAS :

    1385018-58-5

  • Molecular Formula : C28H29NO3

  • Molecular Weight : 427.53

stdClass Object
(
    [pname] => Agomelatine Dimer Urea
    [catalogue_number] => PA 01 31520
    [category_ids] => ,79,80,75,78,70,82,
    [chemical_name] => 
    [weight] => 428.52
    [form] => C27H28N2O3
    [cas] => 185421-27-6
    [pslug] => 185421-27-6-agomelatine-dimer-urea-pa0131520
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PA 01 31520
PA 01 31520

Agomelatine Dimer Urea


  • Catalogue No.:PA 01 31520

  • CAS :

    185421-27-6

  • Molecular Formula : C27H28N2O3

  • Molecular Weight : 428.52

stdClass Object
(
    [pname] => Desacetyl-7-desmethyl Agomelatine Hydrobromide
    [catalogue_number] => PA 01 31530
    [category_ids] => ,79,80,75,78,70,82,
    [chemical_name] => 
    [weight] => 268.15
    [form] => C12H14BrNO
    [cas] => 144705-51-1
    [pslug] => 144705-51-1-desacetyl-7-desmethyl-agomelatine-hydrobromide-pa0131530
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PA 01 31530
PA 01 31530

Desacetyl-7-desmethyl Agomelatine Hydrobromide


  • Catalogue No.:PA 01 31530

  • CAS :

    144705-51-1

  • Molecular Formula : C12H14BrNO

  • Molecular Weight : 268.15

stdClass Object
(
    [pname] => 7-Methoxy-1-naphthylacetonitrile
    [catalogue_number] => PA 01 0311000
    [category_ids] => ,75,76,70,78,82,
    [chemical_name] => 
    [weight] => 197.24
    [form] => C13H11NO
    [cas] => 138113-08-3
    [pslug] => 138113-08-3-7-methoxy-1-naphthylacetonitrile-pa010311000
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PA 01 0311000
PA 01 0311000

7-Methoxy-1-naphthylacetonitrile


  • Catalogue No.:PA 01 0311000

  • CAS :

    138113-08-3

  • Molecular Formula : C13H11NO

  • Molecular Weight : 197.24

stdClass Object
(
    [pname] => Agomelatine-d3 (acetamide-2,2,2-d3)
    [catalogue_number] => PA STI 088271
    [category_ids] => ,98,78,75,76,82,
    [chemical_name] => 
    [weight] => 246.32
    [form] => C15H14D3NO2
    [cas] => 1079389-38-0
    [pslug] => 1079389-38-0-agomelatine-d3-acetamide-2-2-2-d3-pasti088271
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PA STI 088271
PA STI 088271

Agomelatine-d3 (acetamide-2,2,2-d3)


  • Catalogue No.:PA STI 088271

  • CAS :

    1079389-38-0

  • Molecular Formula : C15H14D3NO2

  • Molecular Weight : 246.32

stdClass Object
(
    [pname] => 3,4-Dihydroagomelatine
    [catalogue_number] => PA 01 0311001
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 245.32
    [form] => C15H19NO2
    [cas] => 1352139-51-5
    [pslug] => 1352139-51-5-3-4-dihydroagomelatine-pa010311001
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PA 01 0311001
PA 01 0311001

3,4-Dihydroagomelatine


  • Catalogue No.:PA 01 0311001

  • CAS :

    1352139-51-5

  • Molecular Formula : C15H19NO2

  • Molecular Weight : 245.32

stdClass Object
(
    [pname] => (E)-N-[2-(3,4-Dihydro-7-methoxy-1(2H)-naphthalenylidene)ethyl]acetamide
    [catalogue_number] => PA 01 0311003
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 245.32
    [form] => C15H19NO2
    [cas] => 178677-39-9
    [pslug] => 178677-39-9-e-n-2-3-4-dihydro-7-methoxy-1-2h-naphthalenylidene-ethyl-acetamide-pa010311003
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PA 01 0311003
PA 01 0311003

(E)-N-[2-(3,4-Dihydro-7-methoxy-1(2H)-naphthalenylidene)ethyl]acetamide


  • Catalogue No.:PA 01 0311003

  • CAS :

    178677-39-9

  • Molecular Formula : C15H19NO2

  • Molecular Weight : 245.32

stdClass Object
(
    [pname] => N-Acetyl-N-[2-(7-methoxy-1-naphthalenyl)ethyl]acetamide
    [catalogue_number] => PA 01 0311004
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 285.34
    [form] => C17H19NO3
    [cas] => 1379005-34-1
    [pslug] => 1379005-34-1-n-acetyl-n-2-7-methoxy-1-naphthalenyl-ethyl-acetamide-pa010311004
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PA 01 0311004
PA 01 0311004

N-Acetyl-N-[2-(7-methoxy-1-naphthalenyl)ethyl]acetamide


  • Catalogue No.:PA 01 0311004

  • CAS :

    1379005-34-1

  • Molecular Formula : C17H19NO3

  • Molecular Weight : 285.34

stdClass Object
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    [pname] => 7-Desmethylagomelatine
    [catalogue_number] => PA 01 0311005
    [category_ids] => ,93,78,75,76,82,
    [chemical_name] => 
    [weight] => 229.28
    [form] => C14H15NO2
    [cas] => 152302-45-9
    [pslug] => 152302-45-9-7-desmethylagomelatine-pa010311005
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PA 01 0311005
PA 01 0311005

7-Desmethylagomelatine


  • Catalogue No.:PA 01 0311005

  • CAS :

    152302-45-9

  • Molecular Formula : C14H15NO2

  • Molecular Weight : 229.28

stdClass Object
(
    [pname] => 7-Desmethyl-3-hydroxyagomelatine
    [catalogue_number] => PA 01 0311006
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 245.28
    [form] => C14H15NO3
    [cas] => 166527-00-0
    [pslug] => 166527-00-0-7-desmethyl-3-hydroxyagomelatine-pa010311006
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PA 01 0311006
PA 01 0311006

7-Desmethyl-3-hydroxyagomelatine


  • Catalogue No.:PA 01 0311006

  • CAS :

    166527-00-0

  • Molecular Formula : C14H15NO3

  • Molecular Weight : 245.28

stdClass Object
(
    [pname] => 3-Hydroxyagomelatine
    [catalogue_number] => PA 01 0311002
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 259.31
    [form] => C15H17NO3
    [cas] => 166526-99-4
    [pslug] => 166526-99-4-3-hydroxyagomelatine-pa010311002
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PA 01 0311002
PA 01 0311002

3-Hydroxyagomelatine


  • Catalogue No.:PA 01 0311002

  • CAS :

    166526-99-4

  • Molecular Formula : C15H17NO3

  • Molecular Weight : 259.31

stdClass Object
(
    [pname] => N-(2-(7-Methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)ethyl)acetamide
    [catalogue_number] => PA 01 31540
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 247.33
    [form] => C15H21NO2
    [cas] => 178677-49-1
    [pslug] => 178677-49-1-n-2-7-methoxy-1-2-3-4-tetrahydronaphthalen-1-yl-ethyl-acetamide-pa0131540
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PA 01 31540
PA 01 31540

N-(2-(7-Methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)ethyl)acetamide


  • Catalogue No.:PA 01 31540

  • CAS :

    178677-49-1

  • Molecular Formula : C15H21NO2

  • Molecular Weight : 247.33

stdClass Object
(
    [pname] => 2-(7-Methoxynaphthalen-1-yl)acetamide
    [catalogue_number] => PA 01 0311007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 215.25
    [form] => C13H13NO2
    [cas] => 138113-07-2
    [pslug] => 138113-07-2-2-7-methoxynaphthalen-1-yl-acetamide-pa010311007
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PA 01 0311007
PA 01 0311007

2-(7-Methoxynaphthalen-1-yl)acetamide


  • Catalogue No.:PA 01 0311007

  • CAS :

    138113-07-2

  • Molecular Formula : C13H13NO2

  • Molecular Weight : 215.25

stdClass Object
(
    [pname] => N-Deacetyl-n-formyl agomelatine
    [catalogue_number] => PA 01 0311008
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 229.28
    [form] => C14H15NO2
    [cas] => 138113-05-0
    [pslug] => 138113-05-0-n-deacetyl-n-formyl-agomelatine-pa010311008
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PA 01 0311008
PA 01 0311008

N-Deacetyl-n-formyl agomelatine


  • Catalogue No.:PA 01 0311008

  • CAS :

    138113-05-0

  • Molecular Formula : C14H15NO2

  • Molecular Weight : 229.28

stdClass Object
(
    [pname] => Agomelatine acetic acid ethyl ester
    [catalogue_number] => PA 01 0311009
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 246.31
    [form] =>  C15H18O3
    [cas] => 6836-20-0
    [pslug] => 6836-20-0-agomelatine-acetic-acid-ethyl-ester-pa010311009
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PA 01 0311009
PA 01 0311009

Agomelatine acetic acid ethyl ester


  • Catalogue No.:PA 01 0311009

  • CAS :

    6836-20-0

  • Molecular Formula : C15H18O3

  • Molecular Weight : 246.31

stdClass Object
(
    [pname] => (E)-2-(7-Methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)acetic acid
    [catalogue_number] => PA 01 0311010
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 218.25
    [form] =>  C13H14O3
    [cas] => 63319-95-9
    [pslug] => 63319-95-9-e-2-7-methoxy-3-4-dihydronaphthalen-1-2h-ylidene-acetic-acid-pa010311010
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PA 01 0311010
PA 01 0311010

(E)-2-(7-Methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)acetic acid


  • Catalogue No.:PA 01 0311010

  • CAS :

    63319-95-9

  • Molecular Formula : C13H14O3

  • Molecular Weight : 218.25

stdClass Object
(
    [pname] => 7-Methoxy-N-[2-(7-methoxy-1-naphthalenyl)ethyl]-1-naphthaleneethanamine
    [catalogue_number] => PA 01 0311011
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 385.51
    [form] =>  C26H27NO2
    [cas] => 1385018-57-4
    [pslug] => 1385018-57-4-7-methoxy-n-2-7-methoxy-1-naphthalenyl-ethyl-1-naphthaleneethanamine-pa010311011
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PA 01 0311011
PA 01 0311011

7-Methoxy-N-[2-(7-methoxy-1-naphthalenyl)ethyl]-1-naphthaleneethanamine


  • Catalogue No.:PA 01 0311011

  • CAS :

    1385018-57-4

  • Molecular Formula : C26H27NO2

  • Molecular Weight : 385.51

stdClass Object
(
    [pname] => 2-(7-Methoxynaphthalen-1-yl)ethanamine hydrochloride
    [catalogue_number] => PA 01 0311012
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 237.73
    [form] => C13H16ClNO
    [cas] => 139525-77-2
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PA 01 0311012
PA 01 0311012

2-(7-Methoxynaphthalen-1-yl)ethanamine hydrochloride


  • Catalogue No.:PA 01 0311012

  • CAS :

    139525-77-2

  • Molecular Formula : C13H16ClNO

  • Molecular Weight : 237.73

stdClass Object
(
    [pname] => 2-(7-Hydroxy-3,4-dihydronaphthalen-1-yl)acetonitrile
    [catalogue_number] => PA 01 0311013
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 185.23
    [form] =>  C12H11NO
    [cas] => 1607465-48-4
    [pslug] => 1607465-48-4-2-7-hydroxy-3-4-dihydronaphthalen-1-yl-acetonitrile-pa010311013
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PA 01 0311013
PA 01 0311013

2-(7-Hydroxy-3,4-dihydronaphthalen-1-yl)acetonitrile


  • Catalogue No.:PA 01 0311013

  • CAS :

    1607465-48-4

  • Molecular Formula : C12H11NO

  • Molecular Weight : 185.23

stdClass Object
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    [pname] => 3,4-Dihydro-7-Hydroxy-1(2H)naphthalenone
    [catalogue_number] => PA 01 0311015
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 162.19
    [form] => C10H10O2
    [cas] => 22009-38-7
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PA 01 0311015
PA 01 0311015

3,4-Dihydro-7-Hydroxy-1(2H)naphthalenone


  • Catalogue No.:PA 01 0311015

  • CAS :

    22009-38-7

  • Molecular Formula : C10H10O2

  • Molecular Weight : 162.19

stdClass Object
(
    [pname] => 8-(2-Aminoethyl)-5,6-Dihydronaphthalen-2-ol Hydrochloride
    [catalogue_number] => PA 01 0311014
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 225.72
    [form] => C12H16ClNO
    [cas] => 1607465-49-5
    [pslug] => 1607465-49-5-8-2-aminoethyl-5-6-dihydronaphthalen-2-ol-hydrochloride-pa010311014
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PA 01 0311014
PA 01 0311014

8-(2-Aminoethyl)-5,6-Dihydronaphthalen-2-ol Hydrochloride


  • Catalogue No.:PA 01 0311014

  • CAS :

    1607465-49-5

  • Molecular Formula : C12H16ClNO

  • Molecular Weight : 225.72

stdClass Object
(
    [pname] => N-(2-(7-Hydrxy-3,4-dihydronaphthalen-1-yl)Ethyl)Acetamide
    [catalogue_number] => PA 01 0311016
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 231.3
    [form] => C14H17NO2
    [cas] => 1607465-50-8
    [pslug] => 1607465-50-8-n-2-7-hydrxy-3-4-dihydronaphthalen-1-yl-ethyl-acetamide-pa010311016
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PA 01 0311016
PA 01 0311016

N-(2-(7-Hydrxy-3,4-dihydronaphthalen-1-yl)Ethyl)Acetamide


  • Catalogue No.:PA 01 0311016

  • CAS :

    1607465-50-8

  • Molecular Formula : C14H17NO2

  • Molecular Weight : 231.3

stdClass Object
(
    [pname] => 7-Methoxy-N-[2-(7-methoxy-1-naphthalenyl)ethyl]-1-naphthaleneethanamine Hydrochloride
    [catalogue_number] => PA 01 0311019
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 421.97
    [form] => C26H28ClNO2
    [cas] => 1623104-92-6
    [pslug] => 1623104-92-6-7-methoxy-n-2-7-methoxy-1-naphthalenyl-ethyl-1-naphthaleneethanamine-hydrochloride-pa010311019
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PA 01 0311019
PA 01 0311019

7-Methoxy-N-[2-(7-methoxy-1-naphthalenyl)ethyl]-1-naphthaleneethanamine Hydrochloride


  • Catalogue No.:PA 01 0311019

  • CAS :

    1623104-92-6

  • Molecular Formula : C26H28ClNO2

  • Molecular Weight : 421.97

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