Tofacitinib-impurities | Pharmaffiliates

tofacitinib

Tofacitinib is used to treat psoriatic arthritis and moderate-to-severe forms of rheumatoid arthritis. It is sold under the brand Xeljanz. Reference standards of Tofacitinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => CP-690550-d3
    [catalogue_number] => PA STI 022680
    [category_ids] => ,81,71,85,83,78,70,82,98,
    [chemical_name] => 
    [weight] => 315.39
    [form] => C16H17D3N6O
    [cas] => NA
    [pslug] => cp-690550-d3-pasti022680
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PA STI 022680

CP-690550-d3


  • Catalogue No.:PA STI 022680

  • CAS :

    NA

  • Molecular Formula : C16H17D3N6O

  • Molecular Weight : 315.39

stdClass Object
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    [pname] => Tofacitinib
    [catalogue_number] => PA 73 06000
    [category_ids] => ,81,71,85,83,78,70,82,
    [chemical_name] => 
    [weight] => 312.38
    [form] => C16H20N6O
    [cas] => 477600-75-2
    [pslug] => 477600-75-2-tofacitinib-api-pa7306000
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PA 73 06000

Tofacitinib


  • Catalogue No.:PA 73 06000

  • CAS :

    477600-75-2

  • Molecular Formula : C16H20N6O

  • Molecular Weight : 312.38

stdClass Object
(
    [pname] => 5,6-Dihydro Tofacitinib
    [catalogue_number] => PA 73 06510
    [category_ids] => 85,83,82,78,75,71,70
    [chemical_name] => 
    [weight] => 314.39
    [form] => C16H22N6O
    [cas] => 1640972-35-5
    [pslug] => 1640972-35-5-5-6-dihydro-tofacitinib-pa7306510
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PA 73 06510

5,6-Dihydro Tofacitinib


  • Catalogue No.:PA 73 06510

  • CAS :

    1640972-35-5

  • Molecular Formula : C16H22N6O

  • Molecular Weight : 314.39

stdClass Object
(
    [pname] => 5H,6H,7H-Pyrrolo[2,3-d]pyrimidin-6-one
    [catalogue_number] => PA 73 0061035
    [category_ids] => ,71,78,70,82,
    [chemical_name] => 
    [weight] => 135.13
    [form] => C6H5N3O
    [cas] => 5817-96-9
    [pslug] => 5817-96-9-5h-6h-7h-pyrrolo-2-3-d-pyrimidin-6-one-pa730061035
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PA 73 0061035

5H,6H,7H-Pyrrolo[2,3-d]pyrimidin-6-one


  • Catalogue No.:PA 73 0061035

  • CAS :

    5817-96-9

  • Molecular Formula : C6H5N3O

  • Molecular Weight : 135.13

stdClass Object
(
    [pname] => 1-((4R)-4-Methyl-3-(methyl(7-nitroso-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)propan-1-one
    [catalogue_number] => PA 73 0061037
    [category_ids] => ,71,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 330.39
    [form] => C16H22N6O2
    [cas] => NA
    [pslug] => 1-4r-4-methyl-3-methyl-7-nitroso-7h-pyrrolo-2-3-d-pyrimidin-4-yl-amino-piperidin-1-yl-propan-1-one-pa730061037
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PA 73 0061037

1-((4R)-4-Methyl-3-(methyl(7-nitroso-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)propan-1-one


  • Catalogue No.:PA 73 0061037

  • CAS :

    NA

  • Molecular Formula : C16H22N6O2

  • Molecular Weight : 330.39

stdClass Object
(
    [pname] => N-(1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
    [catalogue_number] => PA 73 0061041
    [category_ids] => ,81,71,85,83,78,70,82,
    [chemical_name] => 
    [weight] => 335.46
    [form] => C20H25N5
    [cas] => 384337-90-0
    [pslug] => 384337-90-0-n-1-benzyl-4-methylpiperidin-3-yl-n-methyl-7h-pyrrolo-2-3-d-pyrimidin-4-amine-pa730061041
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PA 73 0061041

N-(1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine


  • Catalogue No.:PA 73 0061041

  • CAS :

    384337-90-0

  • Molecular Formula : C20H25N5

  • Molecular Weight : 335.46

stdClass Object
(
    [pname] => Butyl 3-amino-2-cyano-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopent-2-enoate
    [catalogue_number] => PA 73 0061048
    [category_ids] => ,81,71,85,83,78,70,82,
    [chemical_name] => 
    [weight] => 453.55
    [form] => C23H31N7O3
    [cas] => 2716897-36-6
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PA 73 0061048

Butyl 3-amino-2-cyano-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopent-2-enoate


  • Catalogue No.:PA 73 0061048

  • CAS :

    2716897-36-6

  • Molecular Formula : C23H31N7O3

  • Molecular Weight : 453.55

stdClass Object
(
    [pname] => N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
    [catalogue_number] => PA 73 0061052
    [category_ids] => ,71,78,70,82,
    [chemical_name] => 
    [weight] => 321.43
    [form] => C19H23N5
    [cas] => 1640971-94-3
    [pslug] => 1640971-94-3-n-3r-4r-1-benzyl-4-methylpiperidin-3-yl-7h-pyrrolo-2-3-d-pyrimidin-4-amine-pa730061052
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PA 73 0061052

N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine


  • Catalogue No.:PA 73 0061052

  • CAS :

    1640971-94-3

  • Molecular Formula : C19H23N5

  • Molecular Weight : 321.43

stdClass Object
(
    [pname] => N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N-ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
    [catalogue_number] => PA 73 0061053
    [category_ids] => ,71,78,70,82,
    [chemical_name] => 
    [weight] => 349.48
    [form] => C21H27N5
    [cas] => NA
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PA 73 0061053

N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N-ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine


  • Catalogue No.:PA 73 0061053

  • CAS :

    NA

  • Molecular Formula : C21H27N5

  • Molecular Weight : 349.48