sorafenib
A tosylate salt of Sorafenib which is a kinase inhibitor drug. It is used for the treatment of kidney, liver and thyroid cancer. It works by inhibiting the VEGFR-2/PDGFR-beta signaling cascade, thereby blocking tumor angiogenesis. Reference standards of Sorafenib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
(
[pname] => 4-Chloro-N-methylpyridine-2-carboxamide Hydrochloride
[catalogue_number] => PA 19 69520
[category_ids] => ,79,80,71,
[chemical_name] =>
[weight] => 207.06
[form] => C7H8Cl2N2O
[cas] => 882167-77-3
[pslug] => 882167-77-3-4-chloro-n-methylpyridine-2-carboxamide-hydrochloride-pa1969520
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4-Chloro-N-methylpyridine-2-carboxamide Hydrochloride
Catalogue No.:PA 19 69520
Molecular Formula : C7H8Cl2N2O
Molecular Weight : 207.06
stdClass Object
(
[pname] => Sorafenib β-D-Glucuronide
[catalogue_number] => PA 19 69540
[category_ids] => ,70,71,75,79,80,82,89,95,
[chemical_name] =>
[weight] => 640.95
[form] => C27H24ClF3N4O9
[cas] => 1130164-93-0
[pslug] => 1130164-93-0-sorafenib-beta-d-glucuronide-pa1969540
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Sorafenib β-D-Glucuronide
Catalogue No.:PA 19 69540
Molecular Formula : C27H24ClF3N4O9
Molecular Weight : 640.95
stdClass Object
(
[pname] => Sorafenib Hemi-Tosylate
[catalogue_number] => PA 19 69550
[category_ids] => 89,80,79,75,71,82,70
[chemical_name] =>
[weight] => 464.83
[form] => C21H16ClF3N4O3 .1/2 C7H8O3S
[cas] => 2056030-06-7
[pslug] => 2056030-06-7-sorafenib-hemi-tosylate-pa1969550
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Catalogue No.:PA 19 69550
Molecular Formula : C21H16ClF3N4O3 .1/2 C7H8O3S
Molecular Weight : 464.83
stdClass Object
(
[pname] => 4-Chloro-N-methylpyridine-2-carboxamide
[catalogue_number] => PA 46 17620
[category_ids] => ,79,80,71,
[chemical_name] =>
[weight] => 170.6
[form] => C7H7ClN2O
[cas] => 220000-87-3
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4-Chloro-N-methylpyridine-2-carboxamide
stdClass Object
(
[pname] => N-Desmethyl Sorafenib
[catalogue_number] => PA 46 17630
[category_ids] => ,79,80,71,81,78,70,82,
[chemical_name] =>
[weight] => 450.8
[form] => C20H14ClF3N4O3
[cas] => 284461-74-1
[pslug] => 284461-74-1-n-desmethyl-sorafenib-pa4617630
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stdClass Object
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[pname] => 1,3-bis(6-Chloro-2',3'-difluoro-[1,1'-biphenyl]-3-yl)urea
[catalogue_number] => PA 46 17640
[category_ids] => 81,79,71,80,70,82,78
[chemical_name] =>
[weight] => 505.29
[form] => C25H14Cl2F4N2O
[cas] => 2514724-45-7
[pslug] => 2514724-45-7-1-3-bis-6-chloro-2-3-difluoro-1-1-biphenyl-3-yl-urea-pa4617640
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1,3-bis(6-Chloro-2',3'-difluoro-[1,1'-biphenyl]-3-yl)urea
Catalogue No.:PA 46 17640
Molecular Formula : C25H14Cl2F4N2O
Molecular Weight : 505.29
