A tosylate salt of Sorafenib which is a kinase inhibitor drug. It is used for the treatment of kidney, liver and thyroid cancer. It works by inhibiting the VEGFR-2/PDGFR-beta signaling cascade, thereby blocking tumor angiogenesis. Reference standards of Sorafenib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => 4-Chloro-N-methylpyridine-2-carboxamide Hydrochloride [catalogue_number] => PA 19 69520 [category_ids] => ,79,80,71, [chemical_name] => [weight] => 207.06 [form] => C7H8Cl2N2O [cas] => 882167-77-3 [pslug] => 882167-77-3-4-chloro-n-methylpyridine-2-carboxamide-hydrochloride-pa1969520 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 69520
CAS :
Molecular Formula : C7H8Cl2N2O
Molecular Weight : 207.06
stdClass Object ( [pname] => Sorafenib β-D-Glucuronide [catalogue_number] => PA 19 69540 [category_ids] => ,70,71,75,79,80,82,89,95, [chemical_name] => [weight] => 640.95 [form] => C27H24ClF3N4O9 [cas] => 1130164-93-0 [pslug] => 1130164-93-0-sorafenib-beta-d-glucuronide-pa1969540 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 69540
Molecular Formula : C27H24ClF3N4O9
Molecular Weight : 640.95
stdClass Object ( [pname] => Sorafenib Hemi-Tosylate [catalogue_number] => PA 19 69550 [category_ids] => 89,80,79,75,71,82,70 [chemical_name] => [weight] => 464.83 [form] => C21H16ClF3N4O3 .1/2 C7H8O3S [cas] => 2056030-06-7 [pslug] => 2056030-06-7-sorafenib-hemi-tosylate-pa1969550 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 69550
Molecular Formula : C21H16ClF3N4O3 .1/2 C7H8O3S
Molecular Weight : 464.83
stdClass Object ( [pname] => 4-Chloro-N-methylpyridine-2-carboxamide [catalogue_number] => PA 46 17620 [category_ids] => ,79,80,71, [chemical_name] => [weight] => 170.6 [form] => C7H7ClN2O [cas] => 220000-87-3 [pslug] => 220000-87-3-4-chloro-n-methylpyridine-2-carboxamide-pa4617620 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 46 17620
Molecular Formula : C7H7ClN2O
Molecular Weight : 170.6
stdClass Object ( [pname] => N-Desmethyl Sorafenib [catalogue_number] => PA 46 17630 [category_ids] => ,79,80,71,81,78,70,82, [chemical_name] => [weight] => 450.8 [form] => C20H14ClF3N4O3 [cas] => 284461-74-1 [pslug] => 284461-74-1-n-desmethyl-sorafenib-pa4617630 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 46 17630
Molecular Formula : C20H14ClF3N4O3
Molecular Weight : 450.8
stdClass Object ( [pname] => 1,3-bis(6-Chloro-2',3'-difluoro-[1,1'-biphenyl]-3-yl)urea [catalogue_number] => PA 46 17640 [category_ids] => 81,79,71,80,70,82,78 [chemical_name] => [weight] => 505.29 [form] => C25H14Cl2F4N2O [cas] => 2514724-45-7 [pslug] => 2514724-45-7-1-3-bis-6-chloro-2-3-difluoro-1-1-biphenyl-3-yl-urea-pa4617640 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 46 17640
Molecular Formula : C25H14Cl2F4N2O
Molecular Weight : 505.29
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