Isavuconazole-impurities | Pharmaffiliates

isavuconazole

Isavuconazonium is used to treat invasive aspergillosis and invasive mucormycosis in adults ages 18 years and older. It is under the brand name Cresemba. It is a prodrug of isavuconazole. Reference standards of Isavuconazole API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => Isavuconazole - API Standards 
    [catalogue_number] => PA 09 42000
    [category_ids] => 88,71,80,82,78,70,69
    [chemical_name] => 
    [weight] => 437.47
    [form] => C22H17F2N5OS
    [cas] => 241479-67-4
    [pslug] => 241479-67-4-isavuconazole-api-pa0942000
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PA 09 42000

Isavuconazole - API Standards


  • Catalogue No.:PA 09 42000

  • CAS :

    241479-67-4

  • Molecular Formula : C22H17F2N5OS

  • Molecular Weight : 437.47

stdClass Object
(
    [pname] => Isavuconazonium Sulfate
    [catalogue_number] => PA 09 42510
    [category_ids] => ,80,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 814.84
    [form] => C35H36F2N8O9S2
    [cas] => 946075-13-4
    [pslug] => 946075-13-4-isavuconazonium-sulfate-pa0942510
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PA 09 42510

Isavuconazonium Sulfate


  • Catalogue No.:PA 09 42510

  • CAS :

    946075-13-4

  • Molecular Formula : C35H36F2N8O9S2

  • Molecular Weight : 814.84

stdClass Object
(
    [pname] => Isavuconazole-d4
    [catalogue_number] => PA STI 053620
    [category_ids] => ,80,69,71,98,78,70,82,88,
    [chemical_name] => 
    [weight] => 441.49
    [form] => C22H13D4F2N5OS
    [cas] => 1346598-58-0
    [pslug] => 1346598-58-0-isavuconazole-d4-pasti053620
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PA STI 053620

Isavuconazole-d4


  • Catalogue No.:PA STI 053620

  • CAS :

    1346598-58-0

  • Molecular Formula : C22H13D4F2N5OS

  • Molecular Weight : 441.49

stdClass Object
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    [pname] => Isavuconazole Methyl Ester Impurity
    [catalogue_number] => PA 09 0421018
    [category_ids] => ,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 847.86
    [form] => C36H39F2N7O11S2
    [cas] => NA
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PA 09 0421018

Isavuconazole Methyl Ester Impurity


  • Catalogue No.:PA 09 0421018

  • CAS :

    NA

  • Molecular Formula : C36H39F2N7O11S2

  • Molecular Weight : 847.86

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    [pname] => 4-(1-(((3-(((N-(tert-Butoxycarbonyl)-N-methylglycyl)oxy)methyl)pyridin-2-yl)(methyl)carbamoyl)oxy)ethyl)-1-((2R,3R)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-1H-1,2,4-triazol-4-ium Chloride
    [catalogue_number] => PA 09 0421019
    [category_ids] => ,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 853.34
    [form] => C40H43ClF2N8O7S
    [cas] => 338990-63-9
    [pslug] => 338990-63-9-4-1-3-n-tert-butoxycarbonyl-n-methylglycyl-oxy-methyl-pyridin-2-yl-methyl-carbamoyl-oxy-ethyl-1-2r-3r-3-4-4-cyanophenyl-thiazol-2-yl-2-2-5-difluorophenyl-2-hydroxybutyl-1h-1-2-4-triazol-4-ium-chloride-pa090421019
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PA 09 0421019

4-(1-(((3-(((N-(tert-Butoxycarbonyl)-N-methylglycyl)oxy)methyl)pyridin-2-yl)(methyl)carbamoyl)oxy)ethyl)-1-((2R,3R)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-1H-1,2,4-triazol-4-ium Chloride


  • Catalogue No.:PA 09 0421019

  • CAS :

    338990-63-9

  • Molecular Formula : C40H43ClF2N8O7S

  • Molecular Weight : 853.34

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(
    [pname] => 1-((2R,3R)-3-(4-(4-(tert-Butylcarbamoyl)phenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-4-(1-((methyl(3-(((methylglycyl)oxy)methyl)pyridin-2-yl)carbamoyl)oxy)ethyl)-1H-1,2,4-triazol-4-ium Chloride
    [catalogue_number] => PA 09 0421020
    [category_ids] => ,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 827.35
    [form] => C39H45ClF2N8O6S
    [cas] => NA
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PA 09 0421020

1-((2R,3R)-3-(4-(4-(tert-Butylcarbamoyl)phenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-4-(1-((methyl(3-(((methylglycyl)oxy)methyl)pyridin-2-yl)carbamoyl)oxy)ethyl)-1H-1,2,4-triazol-4-ium Chloride


  • Catalogue No.:PA 09 0421020

  • CAS :

    NA

  • Molecular Formula : C39H45ClF2N8O6S

  • Molecular Weight : 827.35

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    [pname] => 4-(1-(((3-(((N-(tert-Butoxycarbonyl)-N-methylglycyl)oxy)methyl)pyridin-2-yl)(methyl)carbamoyl)oxy)ethyl)-1-((2R,3R)-2-(1-(((3-(((N-carboxy-N-methylglycyl)oxy)methyl)pyridin-2-yl)(methyl)carbamoyl)oxy)ethoxy)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)butyl)-1H-1,2,4-triazol-4-ium Chloride
    [catalogue_number] => PA 09 0421021
    [category_ids] => ,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 1176.64
    [form] => C54H60ClF2N11O13S
    [cas] => NA
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PA 09 0421021

4-(1-(((3-(((N-(tert-Butoxycarbonyl)-N-methylglycyl)oxy)methyl)pyridin-2-yl)(methyl)carbamoyl)oxy)ethyl)-1-((2R,3R)-2-(1-(((3-(((N-carboxy-N-methylglycyl)oxy)methyl)pyridin-2-yl)(methyl)carbamoyl)oxy)ethoxy)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)butyl)-1H-1,2,4-triazol-4-ium Chloride


  • Catalogue No.:PA 09 0421021

  • CAS :

    NA

  • Molecular Formula : C54H60ClF2N11O13S

  • Molecular Weight : 1176.64

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    [pname] => 1-((2R,3R)-3-(4-(4-Cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-4-(1-((methyl(3-(((N-methyl-N-nitrosoglycyl)oxy)methyl)pyridin-2-yl)carbamoyl)oxy)ethyl)-1H-1,2,4-triazol-4-ium Hydrogen Sulfate
    [catalogue_number] => PA 09 0421022
    [category_ids] => ,88,71,80,82,78,70,69,
    [chemical_name] => 
    [weight] => 843.83
    [form] => C35H35F2N9O10S2
    [cas] => NA
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PA 09 0421022

1-((2R,3R)-3-(4-(4-Cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-4-(1-((methyl(3-(((N-methyl-N-nitrosoglycyl)oxy)methyl)pyridin-2-yl)carbamoyl)oxy)ethyl)-1H-1,2,4-triazol-4-ium Hydrogen Sulfate


  • Catalogue No.:PA 09 0421022

  • CAS :

    NA

  • Molecular Formula : C35H35F2N9O10S2

  • Molecular Weight : 843.83

stdClass Object
(
    [pname] => 1-(3-(4-(4-Cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-4-(1-(((3-(5,8-dimethyl-2-(3-(((methylglycyl)oxy)methyl)pyridin-2-yl)-3,7,10-trioxo-4,6,11-trioxa-2,8-diazadodecan-12-yl)pyridin-2-yl)(methyl)carbamoyl)oxy)ethyl)-1H-1,2,4-triazol-4-ium Hydrogen Sulfate
    [catalogue_number] => PA 09 0421023
    [category_ids] => ,80,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 1138.14
    [form] => C49H53F2N11O15S2
    [cas] => NA
    [pslug] => 1-3-4-4-cyanophenyl-thiazol-2-yl-2-2-5-difluorophenyl-2-hydroxybutyl-4-1-3-5-8-dimethyl-2-3-methylglycyl-oxy-methyl-pyridin-2-yl-3-7-10-trioxo-4-6-11-trioxa-2-8-diazadodecan-12-yl-pyridin-2-yl-methyl-carbamoyl-oxy-ethyl-1h-1-2-4-triazol-4-ium-hydrogen-sulfate-pa090421023
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PA 09 0421023

1-(3-(4-(4-Cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-4-(1-(((3-(5,8-dimethyl-2-(3-(((methylglycyl)oxy)methyl)pyridin-2-yl)-3,7,10-trioxo-4,6,11-trioxa-2,8-diazadodecan-12-yl)pyridin-2-yl)(methyl)carbamoyl)oxy)ethyl)-1H-1,2,4-triazol-4-ium Hydrogen Sulfate


  • Catalogue No.:PA 09 0421023

  • CAS :

    NA

  • Molecular Formula : C49H53F2N11O15S2

  • Molecular Weight : 1138.14

stdClass Object
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    [pname] => (2-(Methyl((vinyloxy)carbonyl)amino)pyridin-3-yl)methyl methylglycinate
    [catalogue_number] => PA 09 0421032
    [category_ids] => ,88,71,80,82,78,70,69,
    [chemical_name] => 
    [weight] => 279.30
    [form] => C13H17N3O4
    [cas] => 2733698-17-2
    [pslug] => 2733698-17-2-2-methyl-vinyloxy-carbonyl-amino-pyridin-3-yl-methyl-methylglycinate-pa090421032
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PA 09 0421032

(2-(Methyl((vinyloxy)carbonyl)amino)pyridin-3-yl)methyl methylglycinate


  • Catalogue No.:PA 09 0421032

  • CAS :

    2733698-17-2

  • Molecular Formula : C13H17N3O4

  • Molecular Weight : 279.30

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(
    [pname] => 1-((2S,3R)-3-(4-(4-Cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-4-(1-((methyl(3-(((N-methyl-N-(methyl(3-(((methylglycyl)oxy)methyl)pyridin-2-yl)carbamoyl)glycyl)oxy)methyl)pyridin-2-yl)carbamoyl)oxy)ethyl)-1H-1,2,4-triazol-4-ium Hydrogen Sulfate
    [catalogue_number] => PA 09 0421033
    [category_ids] => ,88,71,80,82,78,70,69,
    [chemical_name] => 
    [weight] => 1050.08
    [form] => C46H49F2N11O12S2
    [cas] => NA
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PA 09 0421033

1-((2S,3R)-3-(4-(4-Cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-4-(1-((methyl(3-(((N-methyl-N-(methyl(3-(((methylglycyl)oxy)methyl)pyridin-2-yl)carbamoyl)glycyl)oxy)methyl)pyridin-2-yl)carbamoyl)oxy)ethyl)-1H-1,2,4-triazol-4-ium Hydrogen Sulfate


  • Catalogue No.:PA 09 0421033

  • CAS :

    NA

  • Molecular Formula : C46H49F2N11O12S2

  • Molecular Weight : 1050.08

stdClass Object
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    [pname] => 2-(Methyl((vinyloxy)carbonyl)amino)benzyl methylglycinate Hydrochloride
    [catalogue_number] => PA 09 0421034
    [category_ids] => ,88,71,80,82,78,70,69,
    [chemical_name] => 
    [weight] => 314.77
    [form] => C14H19ClN2O4
    [cas] => NA
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PA 09 0421034

2-(Methyl((vinyloxy)carbonyl)amino)benzyl methylglycinate Hydrochloride


  • Catalogue No.:PA 09 0421034

  • CAS :

    NA

  • Molecular Formula : C14H19ClN2O4

  • Molecular Weight : 314.77

stdClass Object
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    [pname] => 1-((2S,3R)-3-(4-(4-Cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-4-(1-((methyl(3-(((methylglycyl)oxy)methyl)pyridin-2-yl)carbamoyl)oxy)ethyl)-1H-1,2,4-triazol-4-ium Chloride Hydrochloride
    [catalogue_number] => PA 09 0421035
    [category_ids] => ,88,71,80,82,78,70,69,
    [chemical_name] => 
    [weight] => 789.68
    [form] => C35H36Cl2F2N8O5S
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PA 09 0421035

1-((2S,3R)-3-(4-(4-Cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-4-(1-((methyl(3-(((methylglycyl)oxy)methyl)pyridin-2-yl)carbamoyl)oxy)ethyl)-1H-1,2,4-triazol-4-ium Chloride Hydrochloride


  • Catalogue No.:PA 09 0421035

  • CAS :

    NA

  • Molecular Formula : C35H36Cl2F2N8O5S

  • Molecular Weight : 789.68

stdClass Object
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    [pname] => 1-((2S,3S)-3-(4-(4-Cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-4-(1-((methyl(3-(((methylglycyl)oxy)methyl)pyridin-2-yl)carbamoyl)oxy)ethyl)-1H-1,2,4-triazol-4-ium Chloride Hydrochloride
    [catalogue_number] => PA 09 0421036
    [category_ids] => ,88,71,80,82,78,70,69,
    [chemical_name] => 
    [weight] => 789.68
    [form] => C35H36Cl2F2N8O5S
    [cas] => NA
    [pslug] => 1-2s-3s-3-4-4-cyanophenyl-thiazol-2-yl-2-2-5-difluorophenyl-2-hydroxybutyl-4-1-methyl-3-methylglycyl-oxy-methyl-pyridin-2-yl-carbamoyl-oxy-ethyl-1h-1-2-4-triazol-4-ium-chloride-hydrochloride-pa090421036
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PA 09 0421036

1-((2S,3S)-3-(4-(4-Cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-4-(1-((methyl(3-(((methylglycyl)oxy)methyl)pyridin-2-yl)carbamoyl)oxy)ethyl)-1H-1,2,4-triazol-4-ium Chloride Hydrochloride


  • Catalogue No.:PA 09 0421036

  • CAS :

    NA

  • Molecular Formula : C35H36Cl2F2N8O5S

  • Molecular Weight : 789.68

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    [catalogue_number] => PA 09 0421037
    [category_ids] => ,88,71,80,82,78,70,69,
    [chemical_name] => 
    [weight] => 270.28
    [form] => C14H16F2O3
    [cas] => 241479-69-6
    [pslug] => 241479-69-6-2r-1-2-5-difluorophenyl-2-tetrahydro-2h-pyran-2-yl-oxy-propan-1-one-pa090421037
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PA 09 0421037

(2R)-1-(2,5-Difluorophenyl)-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one


  • Catalogue No.:PA 09 0421037

  • CAS :

    241479-69-6

  • Molecular Formula : C14H16F2O3

  • Molecular Weight : 270.28

stdClass Object
(
    [pname] => 2-((1R)-1-(2-(2,5-Difluorophenyl)oxiran-2-yl)ethoxy)tetrahydro-2H-pyran
    [catalogue_number] => PA 09 0421038
    [category_ids] => ,88,71,80,82,78,70,69,
    [chemical_name] => 
    [weight] => 284.3
    [form] => C15H18F2O3
    [cas] => 241479-70-9
    [pslug] => 241479-70-9-2-1r-1-2-2-5-difluorophenyl-oxiran-2-yl-ethoxy-tetrahydro-2h-pyran-pa090421038
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PA 09 0421038

2-((1R)-1-(2-(2,5-Difluorophenyl)oxiran-2-yl)ethoxy)tetrahydro-2H-pyran


  • Catalogue No.:PA 09 0421038

  • CAS :

    241479-70-9

  • Molecular Formula : C15H18F2O3

  • Molecular Weight : 284.3

stdClass Object
(
    [pname] => 1-((2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole
    [catalogue_number] => PA 09 0421039
    [category_ids] => ,88,71,80,82,78,70,69,
    [chemical_name] => 
    [weight] => 251.24
    [form] => C12H11F2N3O
    [cas] => 124627-86-7
    [pslug] => 124627-86-7-1-2-2-4-difluorophenyl-3-methyloxiran-2-yl-methyl-1h-1-2-4-triazole-pa090421039
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PA 09 0421039

1-((2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole


  • Catalogue No.:PA 09 0421039

  • CAS :

    124627-86-7

  • Molecular Formula : C12H11F2N3O

  • Molecular Weight : 251.24

stdClass Object
(
    [pname] => N-Benzylethanimine
    [catalogue_number] => PA 09 0421040
    [category_ids] => ,88,71,80,82,78,70,69,
    [chemical_name] => 
    [weight] => 133.19
    [form] => C9H11N
    [cas] => 34233-75-5
    [pslug] => 34233-75-5-n-benzylethanimine-pa090421040
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PA 09 0421040

N-Benzylethanimine


  • Catalogue No.:PA 09 0421040

  • CAS :

    34233-75-5

  • Molecular Formula : C9H11N

  • Molecular Weight : 133.19