imatinib
Heterocycles
- Imatinib is a small molecule kinase inhibitor used to treat certain types of cancer. It is occasionally referred to as CGP57148B or STI571. It is used in treating chronic myelogenous leukemia, gastrointestinal stromal tumors and a number of other malignancies. Reference standards of Imatinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Imatinib
[catalogue_number] => PA 09 05000
[category_ids] => ,80,71,78,70,82,117,
[chemical_name] =>
[weight] => 493.60
[form] => C29H31N7O
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Catalogue No.:PA 09 05000
Molecular Formula : C29H31N7O
Molecular Weight : 493.60
stdClass Object
(
[pname] => Imatinib (Pyridine)-N-oxide
[catalogue_number] => PA 09 05010
[category_ids] => ,80,71,75,78,70,82,
[chemical_name] =>
[weight] => 509.6
[form] => C29H31N7O2
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Imatinib (Pyridine)-N-oxide
stdClass Object
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[pname] => Imatinib (Piperidine)-N,N-DiOxide
[catalogue_number] => PA 09 05020
[category_ids] => ,80,71,75,78,70,82,
[chemical_name] =>
[weight] => 525.6
[form] => C29H31N7O3
[cas] => 571186-93-1
[pslug] => 571186-93-1-imatinib-piperidine-n-n-dioxide-pa0905020
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Imatinib (Piperidine)-N,N-DiOxide
stdClass Object
(
[pname] => Imatinib (Piperidine)-N,N-DiOxide Methanesulfonate
[catalogue_number] => PA 09 05021
[category_ids] => ,80,71,75,78,70,82,88,
[chemical_name] =>
[weight] => 621.71
[form] => C30H35N7O6S
[cas] => NA
[pslug] => imatinib-piperidine-n-n-dioxide-methanesulfonate-pa0905021
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Imatinib (Piperidine)-N,N-DiOxide Methanesulfonate
Catalogue No.:PA 09 05021
Molecular Formula : C30H35N7O6S
Molecular Weight : 621.71
stdClass Object
(
[pname] => Imatinib - Impurity D
[catalogue_number] => PA 09 05040
[category_ids] => ,82,80,78,75,71,70,
[chemical_name] =>
[weight] => 923.50
[form] => C53H51ClN12O2
[cas] => NA
[pslug] => imatinib-impurity-d-pa0905040
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Catalogue No.:PA 09 05040
Molecular Formula : C53H51ClN12O2
Molecular Weight : 923.50
stdClass Object
(
[pname] => 4-(4-Methylpiperazin-1-ylmethyl)benzoyl chloride Dichydrochloride
[catalogue_number] => PA 09 05510
[category_ids] => ,71,75,80,78,70,82,
[chemical_name] =>
[weight] => 325.66
[form] => C13H19Cl3N2O
[cas] => 106261-64-7
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4-(4-Methylpiperazin-1-ylmethyl)benzoyl chloride Dichydrochloride
Catalogue No.:PA 09 05510
Molecular Formula : C13H19Cl3N2O
Molecular Weight : 325.66
stdClass Object
(
[pname] => Imatinib - Impurity F
[catalogue_number] => PA 09 05520
[category_ids] => ,80,71,75,78,70,82,
[chemical_name] =>
[weight] => 277.32
[form] => C16H15N5
[cas] => 152460-10-1
[pslug] => 152460-10-1-imatinib-impurity-f-pa0905520
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Catalogue No.:PA 09 05520
Molecular Formula : C16H15N5
Molecular Weight : 277.32
stdClass Object
(
[pname] => Imatinib Meta-methyl-piperazine Impurity
[catalogue_number] => PA 09 05530
[category_ids] => ,80,71,75,78,70,82,
[chemical_name] =>
[weight] => 493.6
[form] => C29H31N7O
[cas] => 1246819-59-9
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Imatinib Meta-methyl-piperazine Impurity
stdClass Object
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[pname] => Imatinib (Piperidine)-N4-Oxide
[catalogue_number] => PA 09 05540
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[chemical_name] =>
[weight] => 509.6
[form] => C29H31N7O2
[cas] => 938082-57-6
[pslug] => 938082-57-6-imatinib-piperidine-n4-oxide-pa0905540
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Imatinib (Piperidine)-N4-Oxide
stdClass Object
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[pname] => 1-(Chloromethyl)-1-methyl-4-(4-((4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)piperazin-1-ium chloride
[catalogue_number] => PA 09 05550
[category_ids] => ,80,71,75,78,70,82,
[chemical_name] =>
[weight] => 578.54
[form] => C30H33Cl2N7O
[cas] => NA
[pslug] => 1-chloromethyl-1-methyl-4-4-4-methyl-3-4-pyridin-3-yl-pyrimidin-2-yl-amino-phenyl-carbamoyl-benzyl-piperazin-1-ium-chloride-pa0905550
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1-(Chloromethyl)-1-methyl-4-(4-((4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)piperazin-1-ium chloride
Catalogue No.:PA 09 05550
Molecular Formula : C30H33Cl2N7O
Molecular Weight : 578.54
stdClass Object
(
[pname] => Imatinib Carboxylic Impurity
[catalogue_number] => PA 09 05560
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[chemical_name] =>
[weight] => 307.22
[form] => C13H20Cl2N2O2
[cas] => 106261-49-8
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Imatinib Carboxylic Impurity
Catalogue No.:PA 09 05560
Molecular Formula : C13H20Cl2N2O2
Molecular Weight : 307.22
stdClass Object
(
[pname] => 4-Methyl-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide methanesulfonate
[catalogue_number] => PA 09 28510
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[chemical_name] =>
[weight] => 491.56
[form] => C25H25N5O4S
[cas] => NA
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4-Methyl-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide methanesulfonate
Catalogue No.:PA 09 28510
Molecular Formula : C25H25N5O4S
Molecular Weight : 491.56
stdClass Object
(
[pname] => Gleevec-d8 Mesylate (Imatinib-d8 Mesylate)
[catalogue_number] => PA STI 044270
[category_ids] => ,80,71,78,70,82,117,98,
[chemical_name] =>
[weight] => 597.76
[form] => C30H27D8N7O4S
[cas] => 1092942-83-0
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Gleevec-d8 Mesylate (Imatinib-d8 Mesylate)
Catalogue No.:PA STI 044270
Molecular Formula : C30H27D8N7O4S
Molecular Weight : 597.76
stdClass Object
(
[pname] => Imatinib-d8
[catalogue_number] => PA STI 052670
[category_ids] => ,79,80,71,98,78,70,82,117,
[chemical_name] =>
[weight] => 501.65
[form] => C29H23D8N7O
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Catalogue No.:PA STI 052670
Molecular Formula : C29H23D8N7O
Molecular Weight : 501.65
stdClass Object
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[pname] => Imatinib Meta-methyl-piperazine Impurity-d3
[catalogue_number] => PA STI 052680
[category_ids] => ,80,71,75,98,78,70,82,
[chemical_name] =>
[weight] => 496.62
[form] => C29H28D3N7O
[cas] => 1246819-35-9
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Imatinib Meta-methyl-piperazine Impurity-d3
Catalogue No.:PA STI 052680
Molecular Formula : C29H28D3N7O
Molecular Weight : 496.62
stdClass Object
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[pname] => Imatinib Para-diaminomethylbenzene Impurity-d3
[catalogue_number] => PA STI 052690
[category_ids] => ,80,71,75,98,78,70,82,
[chemical_name] =>
[weight] => 496.62
[form] => C29H28D3N7O
[cas] => 1246819-27-1
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Imatinib Para-diaminomethylbenzene Impurity-d3
Catalogue No.:PA STI 052690
Molecular Formula : C29H28D3N7O
Molecular Weight : 496.62
stdClass Object
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[pname] => N-(4-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
[catalogue_number] => PA 09 05610
[category_ids] => ,80,71,76,75,78,70,82,
[chemical_name] =>
[weight] => 277.32
[form] => C16H15N5
[cas] => 112696-91-0
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N-(4-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
Catalogue No.:PA 09 05610
Molecular Formula : C16H15N5
Molecular Weight : 277.32
stdClass Object
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[pname] => 1,3-Bis(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)urea
[catalogue_number] => PA 09 0051014
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[weight] => 580.66
[form] => C33H28N10O
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1,3-Bis(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)urea
Catalogue No.:PA 09 0051014
Molecular Formula : C33H28N10O
Molecular Weight : 580.66
stdClass Object
(
[pname] => N-(2-Methyl-5-(4-((4-methylpiperazin-1-yl)methyl)benzamido)phenyl)-4-((4-methylpiperazin-1-yl)methyl)-N-(4-(pyridin-3-yl)pyrimidin-2-yl)benzamide
[catalogue_number] => PA 09 0051017
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[weight] => 709.9
[form] => C42H47N9O2
[cas] => 1356565-46-2
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N-(2-Methyl-5-(4-((4-methylpiperazin-1-yl)methyl)benzamido)phenyl)-4-((4-methylpiperazin-1-yl)methyl)-N-(4-(pyridin-3-yl)pyrimidin-2-yl)benzamide
