A multikinase inhibitor, Regorafenib is used in the treatment of metastatic colorectal cancer and advanced gastrointestinal stromal tumors. Shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition.Reference standards of Regorafenib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => 4-(4-Amino-3-fluorophenoxy)-N-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)picolinamide [catalogue_number] => PA 18 49520 [category_ids] => ,79,80,71,76,75,78,70,82,89, [chemical_name] => [weight] => 491.45 [form] => C25H19F2N5O4 [cas] => 2518234-85-8 [pslug] => 2518234-85-8-4-4-amino-3-fluorophenoxy-n-2-fluoro-4-2-methylcarbamoyl-pyridin-4-yl-oxy-phenyl-picolinamide-pa1849520 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 49520
CAS :
Molecular Formula : C25H19F2N5O4
Molecular Weight : 491.45
stdClass Object ( [pname] => 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)picolinic Acid [catalogue_number] => PA 18 49570 [category_ids] => ,71,75,79,80,89, [chemical_name] => [weight] => 469.77 [form] => C20H12ClF4N3O4 [cas] => 1187945-05-6 [pslug] => 1187945-05-6-4-4-3-4-chloro-3-trifluoromethyl-phenyl-ureido-3-fluorophenoxy-picolinic-acid-pa1849570 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 49570
Molecular Formula : C20H12ClF4N3O4
Molecular Weight : 469.77
stdClass Object ( [pname] => (2-Fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamic Acid [catalogue_number] => PA 18 49610 [category_ids] => ,80,78,70,82,79,89, [chemical_name] => [weight] => 305.26 [form] => C14H12FN3O4 [cas] => NA [pslug] => 2-fluoro-4-2-methylcarbamoyl-pyridin-4-yl-oxy-phenyl-carbamic-acid-pa1849610 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 49610
Molecular Formula : C14H12FN3O4
Molecular Weight : 305.26
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