Nilotinib is used to treat Philadelphia chromosome positive chronic myelogenous leukaemia. It is sold under the brand name Tasigna. It is not safe for use during pregnancy. Reference standards of Nilotinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => 4-Methyl-1-[3-nitro-5-(trifluoromethyl)phenyl]-1H-imidazole [catalogue_number] => PA 14 64540 [category_ids] => ,80,71,70,78,82,75,79,89, [chemical_name] => [weight] => 271.2 [form] => C11H8F3N3O2 [cas] => 916975-92-3 [pslug] => 916975-92-3-4-methyl-1-3-nitro-5-trifluoromethyl-phenyl-1h-imidazole-pa1464540 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 64540
CAS :
Molecular Formula : C11H8F3N3O2
Molecular Weight : 271.2
stdClass Object ( [pname] => Nilotinib - Impurity H (Hydrochloride Salt) [catalogue_number] => PA 14 64550 [category_ids] => ,80,71,70,78,82,75,79,89, [chemical_name] => [weight] => 565.98 [form] => C28H23ClF3N7O [cas] => NA [pslug] => -nilotinib-impurity-h-hydrochloride-salt-pa1464550 [latest_product] => 0 [linkproducts] => 1 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 64550
Molecular Formula : C28H23ClF3N7O
Molecular Weight : 565.98
stdClass Object ( [pname] => 3-((4-Chloro-6-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide [catalogue_number] => PA 14 64560 [category_ids] => ,80,71,70,78,82,75,79,89, [chemical_name] => [weight] => 563.96 [form] => C28H21ClF3N7O [cas] => NA [pslug] => 3-4-chloro-6-pyridin-3-yl-pyrimidin-2-yl-amino-4-methyl-n-3-4-methyl-1h-imidazol-1-yl-5-trifluoromethyl-phenyl-benzamide-pa1464560 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 64560
Molecular Formula : C28H21ClF3N7O
Molecular Weight : 563.96
stdClass Object ( [pname] => Nilotinib - Impurity H (Freebase) [catalogue_number] => PA 14 64570 [category_ids] => ,80,71,70,78,82,75,79,89, [chemical_name] => [weight] => 529.52 [form] => C28H22F3N7O [cas] => 641571-15-5 [pslug] => 641571-15-5-nilotinib-impurity-h-freebase-pa1464570 [latest_product] => 0 [linkproducts] => 1 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 64570
Molecular Formula : C28H22F3N7O
Molecular Weight : 529.52
stdClass Object ( [pname] => 3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline Hydrochloride [catalogue_number] => PA 14 64580 [category_ids] => ,80,71,70,78,82,75,79,89, [chemical_name] => [weight] => 291.7 [form] => C12H13ClF3N3 [cas] => NA [pslug] => 3-4-ethyl-1h-imidazol-1-yl-5-trifluoromethyl-aniline-hydrochloride-pa1464580 [latest_product] => 0 [linkproducts] => 1 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 64580
Molecular Formula : C12H13ClF3N3
Molecular Weight : 291.7
stdClass Object ( [pname] => 3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)aniline [catalogue_number] => PA 14 64590 [category_ids] => ,80,71,70,78,82,75,79,89, [chemical_name] => [weight] => 227.19 [form] => C10H8F3N3 [cas] => 943320-48-7 [pslug] => 943320-48-7-3-1h-imidazol-1-yl-5-trifluoromethyl-aniline-pa1464590 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 64590
Molecular Formula : C10H8F3N3
Molecular Weight : 227.19
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