Ponatinib-impurities | Pharmaffiliates

ponatinib

A multi-targeted tyrosine-kinase inhibitor, Ponatinib is used in treating chronic myeloid leukemia. Shows antiangiogenic and antineoplastic activities.Reference standards of Ponatinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => Ponatinib - API Standards 
    [catalogue_number] => PA 16 91000
    [category_ids] => ,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 532.56
    [form] => C29H27F3N6O
    [cas] => 943319-70-8
    [pslug] => 943319-70-8-ponatinib-api-pa1691000
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PA 16 91000

Ponatinib - API Standards


  • Catalogue No.:PA 16 91000

  • CAS :

    943319-70-8

  • Molecular Formula : C29H27F3N6O

  • Molecular Weight : 532.56

stdClass Object
(
    [pname] => 3-Ethynylimidazo[1,2-b]pyridazine
    [catalogue_number] => PA 16 91510
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 143.15
    [form] => C8H5N3
    [cas] => 943320-61-4
    [pslug] => 943320-61-4-3-ethynylimidazo-1-2-b-pyridazine-pa1691510
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PA 16 91510

3-Ethynylimidazo[1,2-b]pyridazine


  • Catalogue No.:PA 16 91510

  • CAS :

    943320-61-4

  • Molecular Formula : C8H5N3

  • Molecular Weight : 143.15

stdClass Object
(
    [pname] => N-(4-Formyl-3-(trifluoromethyl)phenyl)-3-iodo-4-methylbenzamide
    [catalogue_number] => PA 16 91520
    [category_ids] => ,71,80,79,78,70,82,89,
    [chemical_name] => 
    [weight] => 433.16
    [form] => C16H11F3INO2
    [cas] => 1638193-91-5
    [pslug] => 1638193-91-5-n-4-formyl-3-trifluoromethyl-phenyl-3-iodo-4-methylbenzamide-pa1691520
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PA 16 91520

N-(4-Formyl-3-(trifluoromethyl)phenyl)-3-iodo-4-methylbenzamide


  • Catalogue No.:PA 16 91520

  • CAS :

    1638193-91-5

  • Molecular Formula : C16H11F3INO2

  • Molecular Weight : 433.16

stdClass Object
(
    [pname] => N-(4-Formyl-3-(trifluoromethyl)phenyl)-3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzamide
    [catalogue_number] => PA 16 91530
    [category_ids] => ,71,80,79,78,70,82,89,
    [chemical_name] => 
    [weight] => 448.4
    [form] => C24H15F3N4O2
    [cas] => 1638193-92-6
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PA 16 91530

N-(4-Formyl-3-(trifluoromethyl)phenyl)-3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzamide


  • Catalogue No.:PA 16 91530

  • CAS :

    1638193-92-6

  • Molecular Formula : C24H15F3N4O2

  • Molecular Weight : 448.4

stdClass Object
(
    [pname] => 3-Ethynyl-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide
    [catalogue_number] => PA 16 91540
    [category_ids] => ,71,80,79,78,70,82,89,
    [chemical_name] => 
    [weight] => 415.45
    [form] => C23H24F3N3O
    [cas] => 957147-18-1
    [pslug] => 957147-18-1-3-ethynyl-4-methyl-n-4-4-methylpiperazin-1-yl-methyl-3-trifluoromethyl-phenyl-benzamide-pa1691540
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PA 16 91540

3-Ethynyl-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide


  • Catalogue No.:PA 16 91540

  • CAS :

    957147-18-1

  • Molecular Formula : C23H24F3N3O

  • Molecular Weight : 415.45

stdClass Object
(
    [pname] => Ponatinib N-Oxide
    [catalogue_number] => PA 16 0911000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 548.57
    [form] => C29H27F3N6O2
    [cas] => 2227480-51-3
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PA 16 0911000

Ponatinib N-Oxide


  • Catalogue No.:PA 16 0911000

  • CAS :

    2227480-51-3

  • Molecular Formula : C29H27F3N6O2

  • Molecular Weight : 548.57

stdClass Object
(
    [pname] => 3,3-(Buta-1,3-diyne-1,4-diyl)bis(4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide);
    [catalogue_number] => PA 16 0911001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 828.9
    [form] => C46H46F6N6O2
    [cas] => 2097674-16-1
    [pslug] => 2097674-16-1-3-3-buta-1-3-diyne-1-4-diyl-bis-4-methyl-n-4-4-methylpiperazin-1-yl-methyl-3-trifluoromethyl-phenyl-benzamide-pa160911001
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PA 16 0911001

3,3-(Buta-1,3-diyne-1,4-diyl)bis(4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide);


  • Catalogue No.:PA 16 0911001

  • CAS :

    2097674-16-1

  • Molecular Formula : C46H46F6N6O2

  • Molecular Weight : 828.9

stdClass Object
(
    [pname] => 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid
    [catalogue_number] => PA 16 0911002
    [category_ids] => ,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 277.28
    [form] => C16H11N3O2
    [cas] => 1300690-48-5
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PA 16 0911002

3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid


  • Catalogue No.:PA 16 0911002

  • CAS :

    1300690-48-5

  • Molecular Formula : C16H11N3O2

  • Molecular Weight : 277.28

stdClass Object
(
    [pname] => Methyl 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoate
    [catalogue_number] => PA 16 0911003
    [category_ids] => ,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 291.31
    [form] => C17H13N3O2
    [cas] => 1356385-96-0
    [pslug] => 1356385-96-0-methyl-3-imidazo-1-2-b-pyridazin-3-ylethynyl-4-methylbenzoate-pa160911003
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PA 16 0911003

Methyl 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoate


  • Catalogue No.:PA 16 0911003

  • CAS :

    1356385-96-0

  • Molecular Formula : C17H13N3O2

  • Molecular Weight : 291.31

stdClass Object
(
    [pname] => 4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline
    [catalogue_number] => PA 16 0911004
    [category_ids] => ,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 273.3
    [form] => C13H18F3N3
    [cas] => 694499-26-8
    [pslug] => 694499-26-8-4-4-methylpiperazin-1-yl-methyl-3-trifluoromethyl-aniline-pa160911004
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PA 16 0911004

4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline


  • Catalogue No.:PA 16 0911004

  • CAS :

    694499-26-8

  • Molecular Formula : C13H18F3N3

  • Molecular Weight : 273.3

stdClass Object
(
    [pname] => 3,5-bis(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide
    [catalogue_number] => PA 16 0911005
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 673.7
    [form] => C37H30F3N9O
    [cas] => NA
    [pslug] => 3-5-bis-imidazo-1-2-b-pyridazin-3-ylethynyl-4-methyl-n-4-4-methylpiperazin-1-yl-methyl-3-trifluoromethyl-phenyl-benzamide-pa160911005
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PA 16 0911005

3,5-bis(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide


  • Catalogue No.:PA 16 0911005

  • CAS :

    NA

  • Molecular Formula : C37H30F3N9O

  • Molecular Weight : 673.7

stdClass Object
(
    [pname] => 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-nitrosopiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide
    [catalogue_number] => PA 16 0911006
    [category_ids] => ,71,78,70,82,
    [chemical_name] => 
    [weight] => 547.54
    [form] => C28H24F3N7O2
    [cas] => NA
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PA 16 0911006

3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-nitrosopiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide


  • Catalogue No.:PA 16 0911006

  • CAS :

    NA

  • Molecular Formula : C28H24F3N7O2

  • Molecular Weight : 547.54

stdClass Object
(
    [pname] => 4-((4-Nitrosopiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline
    [catalogue_number] => PA 16 0911007
    [category_ids] => ,71,78,70,82,
    [chemical_name] => 
    [weight] => 288.27
    [form] => C12H15F3N4O
    [cas] => NA
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PA 16 0911007

4-((4-Nitrosopiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline


  • Catalogue No.:PA 16 0911007

  • CAS :

    NA

  • Molecular Formula : C12H15F3N4O

  • Molecular Weight : 288.27