leflunomide

Fine chemicals - An immunomodulatory drug, Leflunomide is used to treat rheumatoid arthritis and psoriatic arthritis. An inhibitor of enzyme dihydroorotate dehydrogenase which plays a key role in the synthesis of uridine monophosphate (rUMP), which is required for the synthesis of DNA and RNA. Reference standards of Leflunomide API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Leflunomide
    [catalogue_number] => PA 12 08000
    [category_ids] => ,82,81,80,78,71,70,
    [chemical_name] => 
    [weight] => 270.21
    [form] => C12H9F3N2O2
    [cas] => 75706-12-6
    [pslug] => 75706-12-6-leflunomide-api-pa1208000
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 12 08000
PA 12 08000

Leflunomide

  • Catalogue No.:PA 12 08000

  • CAS :

    75706-12-6

  • Molecular Formula : C12H9F3N2O2

  • Molecular Weight : 270.21

Enquire
Details 
stdClass Object
(
    [pname] => Leflunomide - Impurity B
    [catalogue_number] => PA 12 08020
    [category_ids] => ,117,76,82,78,75,70,
    [chemical_name] => 
    [weight] => 270.21
    [form] => C12H9F3N2O2
    [cas] => 163451-81-8
    [pslug] => 163451-81-8-leflunomide-impurity-b-pa1208020
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 12 08020
PA 12 08020

Leflunomide - Impurity B

  • Catalogue No.:PA 12 08020

  • CAS :

    163451-81-8

  • Molecular Formula : C12H9F3N2O2

  • Molecular Weight : 270.21

Enquire
Details 
stdClass Object
(
    [pname] => Leflunomide - Impurity C
    [catalogue_number] => PA 12 08030
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 270.21
    [form] => C12H9F3N2O2
    [cas] => 61643-23-0
    [pslug] => 61643-23-0-leflunomide-impurity-c-pa1208030
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 12 08030
PA 12 08030

Leflunomide - Impurity C

  • Catalogue No.:PA 12 08030

  • CAS :

    61643-23-0

  • Molecular Formula : C12H9F3N2O2

  • Molecular Weight : 270.21

Enquire
Details 
stdClass Object
(
    [pname] => Leflunomide - Impurity D
    [catalogue_number] => PA 12 08040
    [category_ids] => ,71,70,78,82,
    [chemical_name] => 
    [weight] => 127.10
    [form] => C5H5NO3
    [cas] => 42831-50-5
    [pslug] => 42831-50-5-leflunomide-impurity-d-pa1208040
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 12 08040
PA 12 08040

Leflunomide - Impurity D

  • Catalogue No.:PA 12 08040

  • CAS :

    42831-50-5

  • Molecular Formula : C5H5NO3

  • Molecular Weight : 127.10

Enquire
Details 
stdClass Object
(
    [pname] => Leflunomide - Impurity E
    [catalogue_number] => PA 12 08050
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 270.21
    [form] => C12H9F3N2O2
    [cas] => 208401-20-1
    [pslug] => 208401-20-1-leflunomide-impurity-e-pa1208050
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 12 08050
PA 12 08050

Leflunomide - Impurity E

  • Catalogue No.:PA 12 08050

  • CAS :

    208401-20-1

  • Molecular Formula : C12H9F3N2O2

  • Molecular Weight : 270.21

Enquire
Details 
stdClass Object
(
    [pname] => Leflunomide - Impurity F
    [catalogue_number] => PA 12 08060
    [category_ids] => ,70,71,75,78,80,82,
    [chemical_name] => 
    [weight] => 270.21
    [form] => C12H9F3N2O2
    [cas] => 1403564-06-6
    [pslug] => 1403564-06-6-leflunomide-impurity-f-pa1208060
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 12 08060
PA 12 08060

Leflunomide - Impurity F

  • Catalogue No.:PA 12 08060

  • CAS :

    1403564-06-6

  • Molecular Formula : C12H9F3N2O2

  • Molecular Weight : 270.21

Enquire
Details 
stdClass Object
(
    [pname] => Leflunomide - Impurity G
    [catalogue_number] => PA 12 08070
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 216.24
    [form] => C12 H12 N2 O2
    [cas] => 724429-16-7
    [pslug] => 724429-16-7-leflunomide-impurity-g-pa1208070
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 12 08070
PA 12 08070

Leflunomide - Impurity G

  • Catalogue No.:PA 12 08070

  • CAS :

    724429-16-7

  • Molecular Formula : C12 H12 N2 O2

  • Molecular Weight : 216.24

Enquire
Details 
stdClass Object
(
    [pname] => 3-Methylisoxazole-4-carboxylic Acid
    [catalogue_number] => PA 12 08510
    [category_ids] => ,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 127.1
    [form] => C5H5NO3
    [cas] => 17153-20-7
    [pslug] => 17153-20-7-3-methylisoxazole-4-carboxylic-acid-pa1208510
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 12 08510
PA 12 08510

3-Methylisoxazole-4-carboxylic Acid

  • Catalogue No.:PA 12 08510

  • CAS :

    17153-20-7

  • Molecular Formula : C5H5NO3

  • Molecular Weight : 127.1

Enquire
Details 
stdClass Object
(
    [pname] => 5-Methylisoxazole-3-carboxylic-d4 Acid
    [catalogue_number] => PA STI 062330
    [category_ids] => ,71,75,98,78,70,82,
    [chemical_name] => 
    [weight] => 131.12
    [form] => C5HD4NO3
    [cas] => 1267623-84-6
    [pslug] => 1267623-84-6-5-methylisoxazole-3-carboxylic-d4-acid-pasti062330
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA STI 062330
PA STI 062330

5-Methylisoxazole-3-carboxylic-d4 Acid

  • Catalogue No.:PA STI 062330

  • CAS :

    1267623-84-6

  • Molecular Formula : C5HD4NO3

  • Molecular Weight : 131.12

Enquire
Details 
stdClass Object
(
    [pname] => 5-Hydroxy Leflunomide-d4 (Metabolite M2)
    [catalogue_number] => PA STI 049540
    [category_ids] => ,80,71,98,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 290.23
    [form] => C12H5D4F3N2O3
    [cas] => 1794789-76-6
    [pslug] => 1794789-76-6-5-hydroxy-leflunomide-d4-metabolite-m2-pasti049540
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA STI 049540
PA STI 049540

5-Hydroxy Leflunomide-d4 (Metabolite M2)

  • Catalogue No.:PA STI 049540

  • CAS :

    1794789-76-6

  • Molecular Formula : C12H5D4F3N2O3

  • Molecular Weight : 290.23

Enquire
Details 
stdClass Object
(
    [pname] => Leflunomide-d4
    [catalogue_number] => PA STI 056310
    [category_ids] => ,80,71,98,78,70,82,81,
    [chemical_name] => 
    [weight] => 274.23
    [form] => C12H5D4F3N2O2
    [cas] => 1189987-23-2
    [pslug] => 1189987-23-2-leflunomide-d4-pasti056310
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA STI 056310
PA STI 056310

Leflunomide-d4

  • Catalogue No.:PA STI 056310

  • CAS :

    1189987-23-2

  • Molecular Formula : C12H5D4F3N2O2

  • Molecular Weight : 274.23

Enquire
Details 
stdClass Object
(
    [pname] => Lenalidomide-d5
    [catalogue_number] => PA STI 056311
    [category_ids] => ,79,71,78,70,82,
    [chemical_name] => 
    [weight] => 264.29
    [form] => C13H8D5N3O3
    [cas] => NA
    [pslug] => lenalidomide-d5-pasti056311
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA STI 056311
PA STI 056311

Lenalidomide-d5

  • Catalogue No.:PA STI 056311

  • CAS :

    NA

  • Molecular Formula : C13H8D5N3O3

  • Molecular Weight : 264.29

Enquire
Details 
stdClass Object
(
    [pname] => rac Lenalidomide-13C5
    [catalogue_number] => PA STI 056320
    [category_ids] => ,98,78,70,82,
    [chemical_name] => 
    [weight] => 264.22
    [form] => C813C5H13N3O3
    [cas] => 1219332-91-8
    [pslug] => 1219332-91-8-rac-lenalidomide-13c5-pasti056320
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA STI 056320
PA STI 056320

rac Lenalidomide-13C5

  • Catalogue No.:PA STI 056320

  • CAS :

    1219332-91-8

  • Molecular Formula : C813C5H13N3O3

  • Molecular Weight : 264.22

Enquire
Details 
stdClass Object
(
    [pname] => 2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide
    [catalogue_number] => PA 12 08530
    [category_ids] => ,117,76,82,78,75,70,
    [chemical_name] => 
    [weight] => 270.21
    [form] => C12H9F3N2O2
    [cas] => 108605-62-5
    [pslug] => 108605-62-5-2-cyano-3-hydroxy-n-4-trifluoromethyl-phenyl-but-2-enamide-pa1208530
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 12 08530
PA 12 08530

2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide

  • Catalogue No.:PA 12 08530

  • CAS :

    108605-62-5

  • Molecular Formula : C12H9F3N2O2

  • Molecular Weight : 270.21

Enquire
Details 
stdClass Object
(
    [pname] => 3-Methylisoxazole-4-carboxylic Acid Ethyl Ester
    [catalogue_number] => PA 12 08540
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 155.15
    [form] => C7H9NO3
    [cas] => 20328-15-8
    [pslug] => 20328-15-8-3-methylisoxazole-4-carboxylic-acid-ethyl-ester-pa1208540
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 12 08540
PA 12 08540

3-Methylisoxazole-4-carboxylic Acid Ethyl Ester

  • Catalogue No.:PA 12 08540

  • CAS :

    20328-15-8

  • Molecular Formula : C7H9NO3

  • Molecular Weight : 155.15

Enquire
Details 
stdClass Object
(
    [pname] => Ethyl 5-Methylisoxazole-4-carboxylate
    [catalogue_number] => PA 12 08550
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 155.15
    [form] => C7H9NO3
    [cas] => 51135-73-0
    [pslug] => 51135-73-0-ethyl-5-methylisoxazole-4-carboxylate-pa1208550
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 12 08550
PA 12 08550

Ethyl 5-Methylisoxazole-4-carboxylate

  • Catalogue No.:PA 12 08550

  • CAS :

    51135-73-0

  • Molecular Formula : C7H9NO3

  • Molecular Weight : 155.15

Enquire
Details 
stdClass Object
(
    [pname] => 5-Hydroxy leflunomide
    [catalogue_number] => PA 12 0081000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 286.21
    [form] => C12H9F3N2O3
    [cas] => 1058722-46-5
    [pslug] => 1058722-46-5-5-hydroxy-leflunomide-pa120081000
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 12 0081000
PA 12 0081000

5-Hydroxy leflunomide

  • Catalogue No.:PA 12 0081000

  • CAS :

    1058722-46-5

  • Molecular Formula : C12H9F3N2O3

  • Molecular Weight : 286.21

Enquire
Details 
stdClass Object
(
    [pname] => Leflunomide - Impurity A (Hydrochloride)
    [catalogue_number] => PA 12 0080011
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 197.59
    [form] => C7H7ClF3N
    [cas] => 90774-69-9
    [pslug] => 90774-69-9-leflunomide-impurity-a-hydrochloride-pa120080011
    [latest_product] => 0
    [linkproducts] => 1
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 12 0080011
PA 12 0080011

Leflunomide - Impurity A (Hydrochloride)

  • Catalogue No.:PA 12 0080011

  • CAS :

    90774-69-9

  • Molecular Formula : C7H7ClF3N

  • Molecular Weight : 197.59

Enquire
Details
Similar products pharmaffiliates 
stdClass Object
(
    [pname] =>  2-Cyano-N-[2-(trifluoromethyl)phenyl]acetamide
    [catalogue_number] => PA 12 0081001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 228.17
    [form] => C10H7F3N2O
    [cas] => 419534-37-5
    [pslug] => 419534-37-5- 2-cyano-n-2-trifluoromethyl-phenyl-acetamide-pa120081001
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 12 0081001
PA 12 0081001

 2-Cyano-N-[2-(trifluoromethyl)phenyl]acetamide

  • Catalogue No.:PA 12 0081001

  • CAS :

    419534-37-5

  • Molecular Formula : C10H7F3N2O

  • Molecular Weight : 228.17

Enquire
Details 
stdClass Object
(
    [pname] => N-(Chloromethyl)-4-(trifluoromethyl)aniline
    [catalogue_number] => PA 12 0081002
    [category_ids] => ,82,81,80,78,71,70,
    [chemical_name] => 
    [weight] => 209.6
    [form] => C8H7ClF3N
    [cas] => 1903709-86-3
    [pslug] => 1903709-86-3-n-chloromethyl-4-trifluoromethyl-aniline-pa120081002
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 12 0081002
PA 12 0081002

N-(Chloromethyl)-4-(trifluoromethyl)aniline

  • Catalogue No.:PA 12 0081002

  • CAS :

    1903709-86-3

  • Molecular Formula : C8H7ClF3N

  • Molecular Weight : 209.6

Enquire
Details
Periodic Table- Pharmaffiliates

Calculators
Periodic Table- Pharmaffiliates

Contact us

Ask A Scientist-Pharmaffiliates

Ask a Scientist
General Help

General Help
pharmaffiliates