deferasirox
An oral ironchelator, Deferasirox is used to reduce chronic iron overload in patients suffering from beta-thalassemia and anemia.. Reference standards of Deferasirox API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
stdClass Object
(
[pname] => Deferasirox
[catalogue_number] => PA 04 13000
[category_ids] => ,80,115,71,78,70,82,
[chemical_name] =>
[weight] => 373.36
[form] => C21H15N3O4
[cas] => 201530-41-8
[pslug] => 201530-41-8-deferasirox-api-pa0413000
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Catalogue No.:PA 04 13000
Molecular Formula : C21H15N3O4
Molecular Weight : 373.36
stdClass Object
(
[pname] => Deferasirox Acyl-β-D-glucuronide
[catalogue_number] => PA 04 13510
[category_ids] => ,70,71,75,76,78,80,82,95,
[chemical_name] =>
[weight] => 549.49
[form] => C27H23N3O10
[cas] => 1233196-91-2
[pslug] => 1233196-91-2-deferasirox-acyl-beta-d-glucuronide-pa0413510
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Deferasirox Acyl-β-D-glucuronide
Catalogue No.:PA 04 13510
Molecular Formula : C27H23N3O10
Molecular Weight : 549.49
stdClass Object
(
[pname] => Deferasirox Ferrate(III) Tripotassium Complex Methanoate Hydrate
[catalogue_number] => PA 04 13520
[category_ids] => ,115,78,70,82,
[chemical_name] =>
[weight] => 1013.93
[form] => C44H36FeK3N6O12
[cas] => 554445-58-8
[pslug] => 554445-58-8-deferasirox-ferrate-iii-tripotassium-complex-methanoate-hydrate-pa0413520
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Deferasirox Ferrate(III) Tripotassium Complex Methanoate Hydrate
Catalogue No.:PA 04 13520
Molecular Formula : C44H36FeK3N6O12
Molecular Weight : 1013.93
stdClass Object
(
[pname] => Deferasirox - Impurity B
[catalogue_number] => PA 04 13530
[category_ids] => ,71,78,70,82,
[chemical_name] =>
[weight] => 239.23
[form] => C14H9NO3
[cas] => 1218-69-5
[pslug] => 1218-69-5-deferasirox-impurity-b-freebase-pa0413530
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Catalogue No.:PA 04 13530
Molecular Formula : C14H9NO3
Molecular Weight : 239.23
stdClass Object
(
[pname] => Defluoro Hydroxy AM-694
[catalogue_number] => PA 04 13550
[category_ids] => ,103,80,71,100,93,78,70,82,
[chemical_name] =>
[weight] => 433.28
[form] => C20H20INO2
[cas] => 335160-94-6
[pslug] => 335160-94-6-defluoro-hydroxy-am-694-pa0413550
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Catalogue No.:PA 04 13550
Molecular Formula : C20H20INO2
Molecular Weight : 433.28
stdClass Object
(
[pname] => Salicylamide
[catalogue_number] => PA 04 13560
[category_ids] => ,79,80,78,70,82,
[chemical_name] =>
[weight] => 137.14
[form] => C7H7NO2
[cas] => 65-45-2
[pslug] => 65-45-2-salicylamide-pa0413560
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Catalogue No.:PA 04 13560
Molecular Formula : C7H7NO2
Molecular Weight : 137.14
stdClass Object
(
[pname] => Deferasirox Isopropyl Ester
[catalogue_number] => PA 04 13570
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 415.45
[form] => C24H21N3O4
[cas] => 1266741-29-0
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Deferasirox Isopropyl Ester
Catalogue No.:PA 04 13570
Molecular Formula : C24H21N3O4
Molecular Weight : 415.45
stdClass Object
(
[pname] => 2-Methoxy-N-(2-methoxybenzoyl)benzamide
[catalogue_number] => PA 04 13580
[category_ids] => ,70,78,82,80,79,
[chemical_name] =>
[weight] => 285.29
[form] => C16H15NO4
[cas] => 331440-01-8
[pslug] => 331440-01-8-2-methoxy-n-2-methoxybenzoyl-benzamide-pa0413580
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2-Methoxy-N-(2-methoxybenzoyl)benzamide
Catalogue No.:PA 04 13580
Molecular Formula : C16H15NO4
Molecular Weight : 285.29
stdClass Object
(
[pname] => 2-Ethoxy-N-(2-hydroxybenzoyl)benzamide
[catalogue_number] => PA 04 13590
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[chemical_name] =>
[weight] => 285.29
[form] => C16H15NO4
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2-Ethoxy-N-(2-hydroxybenzoyl)benzamide
Catalogue No.:PA 04 13590
Molecular Formula : C16H15NO4
Molecular Weight : 285.29
stdClass Object
(
[pname] => Deferasirox Methyl Ester
[catalogue_number] => PA 04 13600
[category_ids] => ,79,80,115,71,78,70,82,
[chemical_name] =>
[weight] => 387.39
[form] => C22H17N3O4
[cas] => 1266741-05-2
[pslug] => 1266741-05-2-deferasirox-methyl-ester-pa0413600
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Catalogue No.:PA 04 13600
Molecular Formula : C22H17N3O4
Molecular Weight : 387.39
stdClass Object
(
[pname] => Deferasirox - Impurity E
[catalogue_number] => PA 04 13610
[category_ids] => ,79,80,115,71,78,70,82,75,
[chemical_name] =>
[weight] => 401.41
[form] => C23H19N3O4
[cas] => 201530-79-2
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Catalogue No.:PA 04 13610
Molecular Formula : C23H19N3O4
Molecular Weight : 401.41
stdClass Object
(
[pname] => Deferasirox - Impurity A
[catalogue_number] => PA 04 13620
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[chemical_name] =>
[weight] => 257.24
[form] => C14H11NO4
[cas] => 1972-71-0
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Catalogue No.:PA 04 13620
Molecular Formula : C14H11NO4
Molecular Weight : 257.24
stdClass Object
(
[pname] => Deferasirox - Impurity C
[catalogue_number] => PA 04 13630
[category_ids] => 70,78,82,71,80
[chemical_name] =>
[weight] => 373.36
[form] => C21H15N3O4
[cas] => 201530-78-1
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Catalogue No.:PA 04 13630
Molecular Formula : C21H15N3O4
Molecular Weight : 373.36
stdClass Object
(
[pname] => Deferasirox - Impurity F (Freebase)
[catalogue_number] => PA 04 13650
[category_ids] => ,79,80,78,70,82,75,
[chemical_name] =>
[weight] => 152.15
[form] => C7H8N2O2
[cas] => 619-67-0
[pslug] => 619-67-0-deferasirox-impurity-f-freebase-pa0413650
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Deferasirox - Impurity F (Freebase)
Catalogue No.:PA 04 13650
Molecular Formula : C7H8N2O2
Molecular Weight : 152.15
stdClass Object
(
[pname] => 2-(2-Salicyloylphenyl)-4H-1,3-benzoxazin-4-one
[catalogue_number] => PA 04 13660
[category_ids] => ,79,80,78,70,82,
[chemical_name] =>
[weight] => 343.33
[form] => C21H13NO4
[cas] => NA
[pslug] => 2-2-salicyloylphenyl-4h-1-3-benzoxazin-4-one-pa0413660
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2-(2-Salicyloylphenyl)-4H-1,3-benzoxazin-4-one
Catalogue No.:PA 04 13660
Molecular Formula : C21H13NO4
Molecular Weight : 343.33
stdClass Object
(
[pname] => 2-((2-hydroxybenzoyl)carbamoyl)phenyl benzoate
[catalogue_number] => PA 04 13670
[category_ids] => ,79,80,78,70,82,
[chemical_name] =>
[weight] => 361.35
[form] => C21H15NO5
[cas] => NA
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2-((2-hydroxybenzoyl)carbamoyl)phenyl benzoate
Catalogue No.:PA 04 13670
Molecular Formula : C21H15NO5
Molecular Weight : 361.35
stdClass Object
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[pname] => 2-Carbamoylphenyl 2-hydroxybenzoate
[catalogue_number] => PA 04 13680
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[weight] => 257.24
[form] => C14H11NO4
[cas] => NA
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2-Carbamoylphenyl 2-hydroxybenzoate
Catalogue No.:PA 04 13680
Molecular Formula : C14H11NO4
Molecular Weight : 257.24
stdClass Object
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[pname] => 2,2'-(Thiobis(2-hydroxy-5,1-phenylene))bis(4H-benzo[e][1,3]oxazin-4-one)
[catalogue_number] => PA 04 13690
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[weight] => 508.5
[form] => C28H16N2O6S
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2,2'-(Thiobis(2-hydroxy-5,1-phenylene))bis(4H-benzo[e][1,3]oxazin-4-one)
stdClass Object
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[pname] => 2,2'-(Sulfinylbis(2-hydroxy-5,1-phenylene))bis(4H-benzo[e][1,3]oxazin-4-one)
[catalogue_number] => PA 04 13700
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[weight] => 524.5
[form] => C28H16N2O7S
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2,2'-(Sulfinylbis(2-hydroxy-5,1-phenylene))bis(4H-benzo[e][1,3]oxazin-4-one)
stdClass Object
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[catalogue_number] => PA 04 13710
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[chemical_name] =>
[weight] => 776.77
[form] => C42H28N6O8S
[cas] => NA
[pslug] => 1-4-carboxyphenyl-3-2-hydroxyphenyl-1h-1-2-4-triazol-5-yl-4-hydroxyphenyl-thio-2-hydroxyphenyl-5-2-hydroxyphenyl-1h-1-2-4-triazol-1-yl-benzoic-acid-pa0413710
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1-(4-Carboxyphenyl)-3-(2-hydroxyphenyl)-1H-1,2,4-triazol-5-yl)-4-hydroxyphenyl)thio)-2-hydroxyphenyl)-5-(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl)benzoic Acid
Catalogue No.:PA 04 13710
Molecular Formula : C42H28N6O8S
Molecular Weight : 776.77
stdClass Object
(
[pname] => 4-(3-(5-((3-(1-(4-Carboxyphenyl)-3-(2-hydroxyphenyl)-1H-1,2,4-triazol-5-yl)-4-hydroxyphenyl)sulfinyl)-2-hydroxyphenyl)-5-(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl)benzoic Acid
[catalogue_number] => PA 04 13720
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[weight] => 792.77
[form] => C42H28N6O9S
[cas] => NA
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4-(3-(5-((3-(1-(4-Carboxyphenyl)-3-(2-hydroxyphenyl)-1H-1,2,4-triazol-5-yl)-4-hydroxyphenyl)sulfinyl)-2-hydroxyphenyl)-5-(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl)benzoic Acid
Catalogue No.:PA 04 13720
Molecular Formula : C42H28N6O9S
Molecular Weight : 792.77
stdClass Object
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[pname] => Deferasirox-d4
[catalogue_number] => PA STI 024870
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[chemical_name] =>
[weight] => 377.39
[form] => C21H11D4N3O4
[cas] => 1133425-75-8
[pslug] => 1133425-75-8-deferasirox-d4-pasti024870
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Catalogue No.:PA STI 024870
Molecular Formula : C21H11D4N3O4
Molecular Weight : 377.39
stdClass Object
(
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[catalogue_number] => PA STI 024871
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[chemical_name] =>
[weight] => 381.41
[form] => C21H7D8N3O4
[cas] => NA
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Catalogue No.:PA STI 024871
Molecular Formula : C21H7D8N3O4
Molecular Weight : 381.41
stdClass Object
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Deferasirox-d4 (Mixture of 6-hydroxyphenyl-d4 isomers)
Catalogue No.:PA STI 024880
Molecular Formula : C21H11D4N3O4
Molecular Weight : 377.39
stdClass Object
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[pname] => Deferasirox-D8 Ferrate(III) Tripotassium Complex Methanoate Hydrate
[catalogue_number] => PA STI 024890
[category_ids] => ,115,78,70,82,98,
[chemical_name] =>
[weight] => 1021.98
[form] => C44H28D8FeK3N6O12
[cas] => NA
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Deferasirox-D8 Ferrate(III) Tripotassium Complex Methanoate Hydrate
Catalogue No.:PA STI 024890
Molecular Formula : C44H28D8FeK3N6O12
Molecular Weight : 1021.98
stdClass Object
(
[pname] => 2-(2-Hydroxyphenyl)-4H-1,3-benzoxazin-4-one-d4 (Mixture of 2-Hydroxyphenyl-d4 & Benzoxazinone-d4)
[catalogue_number] => PA STI 050920
[category_ids] => ,98,78,70,82,
[chemical_name] =>
[weight] => 243.25
[form] => C14H5D4NO3
[cas] => NA
[pslug] => 2-2-hydroxyphenyl-4h-1-3-benzoxazin-4-one-d4-mixture-of-2-hydroxyphenyl-d4-and-benzoxazinone-d4-pasti050920
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2-(2-Hydroxyphenyl)-4H-1,3-benzoxazin-4-one-d4 (Mixture of 2-Hydroxyphenyl-d4 & Benzoxazinone-d4)
Catalogue No.:PA STI 050920
Molecular Formula : C14H5D4NO3
Molecular Weight : 243.25
stdClass Object
(
[pname] => Deferasirox Salicyloyl Ester
[catalogue_number] => PA 04 13730
[category_ids] => ,80,115,71,75,78,70,82,
[chemical_name] =>
[weight] => 493.48
[form] => C28H19N3O6
[cas] => 1395346-28-7
[pslug] => 1395346-28-7-deferasirox-salicyloyl-ester-pa0413730
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Deferasirox Salicyloyl Ester
Catalogue No.:PA 04 13730
Molecular Formula : C28H19N3O6
Molecular Weight : 493.48
stdClass Object
(
[pname] => 4-(3,5-bis(6-Oxocyclohexa-1,4-dien-1-yl)-1H-1,2,4-triazol-1-yl)benzoic Acid
[catalogue_number] => PA 04 13740
[category_ids] => ,80,115,71,75,78,70,82,
[chemical_name] =>
[weight] => 373.37
[form] => C21H15N3O4
[cas] => NA
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4-(3,5-bis(6-Oxocyclohexa-1,4-dien-1-yl)-1H-1,2,4-triazol-1-yl)benzoic Acid
Catalogue No.:PA 04 13740
Molecular Formula : C21H15N3O4
Molecular Weight : 373.37
stdClass Object
(
[pname] => Deferasirox Sulfoxide Dimer
[catalogue_number] => PA 04 13750
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 792.78
[form] => C42H28N6O9S
[cas] => 1688656-84-9
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Deferasirox Sulfoxide Dimer
Catalogue No.:PA 04 13750
Molecular Formula : C42H28N6O9S
Molecular Weight : 792.78
stdClass Object
(
[pname] => 3-Hydrazinobenzoic Acid
[catalogue_number] => PA 04 0131001
[category_ids] => ,80,76,75,71,78,70,82,
[chemical_name] =>
[weight] => 152.15
[form] => C7H8N2O2
[cas] => 38235-71-1
[pslug] => 38235-71-1-3-hydrazinobenzoic-acid-pa040131001
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Catalogue No.:PA 04 0131001
Molecular Formula : C7H8N2O2
Molecular Weight : 152.15
stdClass Object
(
[pname] => Salicylimide, Benzoxazinone analog, Deferasirox 1,2-isomer, Deferasirox 1,3-isomer, Deferasirox and Deferasirox ethyl ester
[catalogue_number] => PA 04 0131002
[category_ids] => ,80,71,76,75,93,78,70,82,
[chemical_name] =>
[weight] => NA
[form] => NA
[cas] => NA
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-pa040131002
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Salicylimide, Benzoxazinone analog, Deferasirox 1,2-isomer, Deferasirox 1,3-isomer, Deferasirox and Deferasirox ethyl ester
stdClass Object
(
[pname] => N-(4-Nitrophenyl)-5-chlorosalicylamide
[catalogue_number] => PA 04 0131003
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 292.68
[form] => C13H9ClN2O4
[cas] => 4638-49-7
[pslug] => 4638-49-7-n-4-nitrophenyl-5-chlorosalicylamide-pa040131003
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N-(4-Nitrophenyl)-5-chlorosalicylamide
Catalogue No.:PA 04 0131003
Molecular Formula : C13H9ClN2O4
Molecular Weight : 292.68
stdClass Object
(
[pname] => 5-Hydroxy Deferasirox (Metabolite M1)
[catalogue_number] => PA 04 0131004
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 389.37
[form] => C21H15N3O5
[cas] => 524746-12-1
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5-Hydroxy Deferasirox (Metabolite M1)
Catalogue No.:PA 04 0131004
Molecular Formula : C21H15N3O5
Molecular Weight : 389.37
stdClass Object
(
[pname] => 3-Hydroxy Deferasirox (Metabolite M2)
[catalogue_number] => PA 04 0131005
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 389.37
[form] => C21H15N3O5
[cas] => 524746-11-0
[pslug] => 524746-11-0-3-hydroxy-deferasirox-metabolite-m2-pa040131005
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3-Hydroxy Deferasirox (Metabolite M2)
Catalogue No.:PA 04 0131005
Molecular Formula : C21H15N3O5
Molecular Weight : 389.37
stdClass Object
(
[pname] => 4-(2-(2-Hydroxybenzoyl)hydrazinyl)benzoic Acid
[catalogue_number] => PA 04 0131006
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 272.26
[form] => C14H12N2O4
[cas] => NA
[pslug] => 4-2-2-hydroxybenzoyl-hydrazinyl-benzoic-acid-pa040131006
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4-(2-(2-Hydroxybenzoyl)hydrazinyl)benzoic Acid
Catalogue No.:PA 04 0131006
Molecular Formula : C14H12N2O4
Molecular Weight : 272.26
stdClass Object
(
[pname] => 4-(5-(2-Chlorophenyl)-3-(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl)benzoic Acid
[catalogue_number] => PA 04 0131007
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 391.81
[form] => C21H14ClN3O3
[cas] => NA
[pslug] => 4-5-2-chlorophenyl-3-2-hydroxyphenyl-1h-1-2-4-triazol-1-yl-benzoic-acid-pa040131007
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4-(5-(2-Chlorophenyl)-3-(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl)benzoic Acid
Catalogue No.:PA 04 0131007
Molecular Formula : C21H14ClN3O3
Molecular Weight : 391.81
stdClass Object
(
[pname] => 4-(2-(2-(4-oxo-4H-Benzo[e][1,3]oxazin-2-yl)phenyl)hydrazinyl)benzoic Acid
[catalogue_number] => PA 04 0131008
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 373.37
[form] => C21H15N3O4
[cas] => NA
[pslug] => 4-2-2-4-oxo-4h-benzo-e1-3-oxazin-2-yl-phenyl-hydrazinyl-benzoic-acid-pa040131008
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4-(2-(2-(4-oxo-4H-Benzo[e][1,3]oxazin-2-yl)phenyl)hydrazinyl)benzoic Acid
Catalogue No.:PA 04 0131008
Molecular Formula : C21H15N3O4
Molecular Weight : 373.37
stdClass Object
(
[pname] => 4-Amino-3-((4-carboxyphenyl)diazenyl)benzoic Acid
[catalogue_number] => PA 04 0131009
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 285.26
[form] => C14H11N3O4
[cas] => 1914179-49-9
[pslug] => 1914179-49-9-4-amino-3-4-carboxyphenyl-diazenyl-benzoic-acid-pa040131009
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4-Amino-3-((4-carboxyphenyl)diazenyl)benzoic Acid
Catalogue No.:PA 04 0131009
Molecular Formula : C14H11N3O4
Molecular Weight : 285.26
stdClass Object
(
[pname] => Deferasirox - Impurity F (Hydrochloride Salt)
[catalogue_number] => PA 04 0130061
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[chemical_name] =>
[weight] => 188.61
[form] => C7H9ClN2O2
[cas] => 24589-77-3
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Deferasirox - Impurity F (Hydrochloride Salt)
Catalogue No.:PA 04 0130061
Molecular Formula : C7H9ClN2O2
Molecular Weight : 188.61
stdClass Object
(
[pname] => Deferasirox 2-Glucuronide
[catalogue_number] => PA 04 0131011
[category_ids] => ,70,71,78,80,82,115,95,
[chemical_name] =>
[weight] => 549.49
[form] => C27H23N3O10
[cas] => 1233196-92-3
[pslug] => 1233196-92-3-deferasirox-2-glucuronide-pa040131011
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Deferasirox 2-Glucuronide
Catalogue No.:PA 04 0131011
Molecular Formula : C27H23N3O10
Molecular Weight : 549.49
stdClass Object
(
[pname] => 2-(4-Oxo-3,4-dihydro-2H-benzo[e][1,3]oxazin-2-yl)phenyl 2-hydroxybenzoate
[catalogue_number] => PA 04 0131012
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 361.35
[form] => C21H15NO5
[cas] => NA
[pslug] => 2-4-oxo-3-4-dihydro-2h-benzo-e-1-3-oxazin-2-yl-phenyl-2-hydroxybenzoate-pa040131012
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2-(4-Oxo-3,4-dihydro-2H-benzo[e][1,3]oxazin-2-yl)phenyl 2-hydroxybenzoate
Catalogue No.:PA 04 0131012
Molecular Formula : C21H15NO5
Molecular Weight : 361.35
stdClass Object
(
[pname] => 2,2'-(1-Phenyl-1H-1,2,4-triazole-3,5-diyl)diphenol
[catalogue_number] => PA 04 0131013
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[chemical_name] =>
[weight] => 329.36
[form] => C20H15N3O2
[cas] => 86245-87-6
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2,2'-(1-Phenyl-1H-1,2,4-triazole-3,5-diyl)diphenol
Catalogue No.:PA 04 0131013
Molecular Formula : C20H15N3O2
Molecular Weight : 329.36
