Darolutamide

Fine chemicals - Darolutamide is used to treat certain types of prostate cancer that has not spread to other parts of the body in men who have not been helped by other medical treatments. It is sold under the brand name Nubeqa. Reference standards of Darolutamide API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Darolutamide
    [catalogue_number] => PA 04 1940000
    [category_ids] => ,78,70,82,75,76,
    [chemical_name] => 
    [weight] => 398.85
    [form] => C19H19ClN6O2
    [cas] => 1297538-32-9
    [pslug] => 1297538-32-9-darolutamide-api-pa041940000
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PA 04 1940000
PA 04 1940000

Darolutamide

  • Catalogue No.:PA 04 1940000

  • CAS :

    1297538-32-9

  • Molecular Formula : C19H19ClN6O2

  • Molecular Weight : 398.85

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Details 
stdClass Object
(
    [pname] => N-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1-nitroso-1H-pyrazole-3-carboxamide
    [catalogue_number] => PA 04 1941001
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 427.85
    [form] => C19H18ClN7O3
    [cas] => NA
    [pslug] => n-s-1-3-3-chloro-4-cyanophenyl-1h-pyrazol-1-yl-propan-2-yl-5-1-hydroxyethyl-1-nitroso-1h-pyrazole-3-carboxamide-pa041941001
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PA 04 1941001
PA 04 1941001

N-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1-nitroso-1H-pyrazole-3-carboxamide

  • Catalogue No.:PA 04 1941001

  • CAS :

    NA

  • Molecular Formula : C19H18ClN7O3

  • Molecular Weight : 427.85

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Details 
stdClass Object
(
    [pname] => 2-Chloro-4-(1-nitroso-1H-pyrazol-3-yl)benzonitrile
    [catalogue_number] => PA 04 1941002
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 232.63
    [form] => C10H5ClN4O
    [cas] => NA
    [pslug] => 2-chloro-4-1-nitroso-1h-pyrazol-3-yl-benzonitrile-pa041941002
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PA 04 1941002
PA 04 1941002

2-Chloro-4-(1-nitroso-1H-pyrazol-3-yl)benzonitrile

  • Catalogue No.:PA 04 1941002

  • CAS :

    NA

  • Molecular Formula : C10H5ClN4O

  • Molecular Weight : 232.63

Enquire
Details 
stdClass Object
(
    [pname] => (S)-5-Acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1-nitroso-1H-pyrazole-3-carboxamide
    [catalogue_number] => PA 04 1941003
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 425.83
    [form] => C19H16ClN7O3
    [cas] => NA
    [pslug] => s-5-acetyl-n-1-3-3-chloro-4-cyanophenyl-1h-pyrazol-1-yl-propan-2-yl-1-nitroso-1h-pyrazole-3-carboxamide-pa041941003
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PA 04 1941003
PA 04 1941003

(S)-5-Acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1-nitroso-1H-pyrazole-3-carboxamide

  • Catalogue No.:PA 04 1941003

  • CAS :

    NA

  • Molecular Formula : C19H16ClN7O3

  • Molecular Weight : 425.83

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Details 
stdClass Object
(
    [pname] => N-Nitroso Darolutamide
    [catalogue_number] => PA 04 1941004
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 427.85
    [form] => C19H18ClN7O3
    [cas] => NA
    [pslug] => n-nitroso-darolutamide-pa041941004
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PA 04 1941004
PA 04 1941004

N-Nitroso Darolutamide

  • Catalogue No.:PA 04 1941004

  • CAS :

    NA

  • Molecular Formula : C19H18ClN7O3

  • Molecular Weight : 427.85

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Details 
stdClass Object
(
    [pname] => (E)-4,4'-(1,3-Dihydroxybut-1-ene-1,3-diyl)bis(2-chlorobenzonitrile)
    [catalogue_number] => PA 04 1941005
    [category_ids] => ,76,78,70,82,
    [chemical_name] => 
    [weight] => 359.21
    [form] => C18H12Cl2N2O2
    [cas] => NA
    [pslug] => e-4-4-1-3-dihydroxybut-1-ene-1-3-diyl-bis-2-chlorobenzonitrile-pa041941005
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PA 04 1941005
PA 04 1941005

(E)-4,4'-(1,3-Dihydroxybut-1-ene-1,3-diyl)bis(2-chlorobenzonitrile)

  • Catalogue No.:PA 04 1941005

  • CAS :

    NA

  • Molecular Formula : C18H12Cl2N2O2

  • Molecular Weight : 359.21

Enquire
Details 
stdClass Object
(
    [pname] => Darolutamide Pyrazol benzonitrile Impurity
    [catalogue_number] => PA 04 1941006
    [category_ids] => ,78,70,82,75,76,
    [chemical_name] => 
    [weight] => 203.63
    [form] => C10H6ClN3
    [cas] => 1297537-37-1
    [pslug] => 1297537-37-1-darolutamide-pyrazol-benzonitrile-impurity-pa041941006
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PA 04 1941006
PA 04 1941006

Darolutamide Pyrazol benzonitrile Impurity

  • Catalogue No.:PA 04 1941006

  • CAS :

    1297537-37-1

  • Molecular Formula : C10H6ClN3

  • Molecular Weight : 203.63

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Details 
stdClass Object
(
    [pname] => 2-Methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)aniline
    [catalogue_number] => PA 04 1941007
    [category_ids] => ,78,70,82,75,76,
    [chemical_name] => 
    [weight] => 204.23
    [form] => C10H12N4O
    [cas] => 1609394-10-6
    [pslug] => 1609394-10-6-2-methoxy-3-1-methyl-1h-1-2-4-triazol-3-yl-aniline-pa041941007
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PA 04 1941007
PA 04 1941007

2-Methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)aniline

  • Catalogue No.:PA 04 1941007

  • CAS :

    1609394-10-6

  • Molecular Formula : C10H12N4O

  • Molecular Weight : 204.23

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Details 
stdClass Object
(
    [pname] => N-((S)-1-(3-(4-Carbamoyl-3-chlorophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide
    [catalogue_number] => PA 04 1941008
    [category_ids] => ,82,78,76,75,70,
    [chemical_name] => 
    [weight] => 416.87
    [form] => C19H21ClN6O3
    [cas] => NA
    [pslug] => n-s-1-3-4-carbamoyl-3-chlorophenyl-1h-pyrazol-1-yl-propan-2-yl-5-1-hydroxyethyl-1h-pyrazole-3-carboxamide-pa041941008
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PA 04 1941008
PA 04 1941008

N-((S)-1-(3-(4-Carbamoyl-3-chlorophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide

  • Catalogue No.:PA 04 1941008

  • CAS :

    NA

  • Molecular Formula : C19H21ClN6O3

  • Molecular Weight : 416.87

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Details 
stdClass Object
(
    [pname] => Darolutamide Benzyl Amine
    [catalogue_number] => PA 04 1941009
    [category_ids] => ,82,78,76,75,70,
    [chemical_name] => 
    [weight] => 402.88
    [form] => C19H23ClN6O2
    [cas] => NA
    [pslug] => darolutamide-benzyl-amine-pa041941009
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PA 04 1941009
PA 04 1941009

Darolutamide Benzyl Amine

  • Catalogue No.:PA 04 1941009

  • CAS :

    NA

  • Molecular Formula : C19H23ClN6O2

  • Molecular Weight : 402.88

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Details 
stdClass Object
(
    [pname] => N-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl-2,3,3,3-d4)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide
    [catalogue_number] => PA STI 089899
    [category_ids] => ,98,78,70,82,
    [chemical_name] => 
    [weight] => 402.88
    [form] => C19H15D4ClN6O2
    [cas] => 2484757-19-7
    [pslug] => 2484757-19-7-n-s-1-3-3-chloro-4-cyanophenyl-1h-pyrazol-1-yl-propan-2-yl-2-3-3-3-d4-5-1-hydroxyethyl-1h-pyrazole-3-carboxamide-pasti089899
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PA STI 089899
PA STI 089899

N-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl-2,3,3,3-d4)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide

  • Catalogue No.:PA STI 089899

  • CAS :

    2484757-19-7

  • Molecular Formula : C19H15D4ClN6O2

  • Molecular Weight : 402.88

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Details 
stdClass Object
(
    [pname] => (S)-4-(1-(2-Aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile Hydrochloride
    [catalogue_number] => PA 04 1941011
    [category_ids] => ,78,70,82,75,76,
    [chemical_name] => 
    [weight] => 297.18
    [form] => C13H14Cl2N4
    [cas] => 2451299-27-5
    [pslug] => 2451299-27-5-s-4-1-2-aminopropyl-1h-pyrazol-3-yl-2-chlorobenzonitrile-hydrochloride-pa041941011
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PA 04 1941011
PA 04 1941011

(S)-4-(1-(2-Aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile Hydrochloride

  • Catalogue No.:PA 04 1941011

  • CAS :

    2451299-27-5

  • Molecular Formula : C13H14Cl2N4

  • Molecular Weight : 297.18

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Details 
stdClass Object
(
    [pname] => 3-Acetyl-1H-pyrazole-5-carboxylic Acid
    [catalogue_number] => PA 04 1941012
    [category_ids] => ,78,70,82,75,76,
    [chemical_name] => 
    [weight] => 154.13
    [form] => C6H6N2O3
    [cas] => 1297537-45-1
    [pslug] => 1297537-45-1-3-acetyl-1h-pyrazole-5-carboxylic-acid-pa041941012
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PA 04 1941012
PA 04 1941012

3-Acetyl-1H-pyrazole-5-carboxylic Acid

  • Catalogue No.:PA 04 1941012

  • CAS :

    1297537-45-1

  • Molecular Formula : C6H6N2O3

  • Molecular Weight : 154.13

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Details 
stdClass Object
(
    [pname] => (S)-5-(1-Hydroxyethyl)-1H-pyrazole-3-carboxylic Acid
    [catalogue_number] => PA 04 1941013
    [category_ids] => ,78,70,82,75,76,
    [chemical_name] => 
    [weight] => 156.14
    [form] => C6H8N2O3
    [cas] => 1401572-44-8
    [pslug] => 1401572-44-8-s-5-1-hydroxyethyl-1h-pyrazole-3-carboxylic-acid-pa041941013
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PA 04 1941013
PA 04 1941013

(S)-5-(1-Hydroxyethyl)-1H-pyrazole-3-carboxylic Acid

  • Catalogue No.:PA 04 1941013

  • CAS :

    1401572-44-8

  • Molecular Formula : C6H8N2O3

  • Molecular Weight : 156.14

Enquire
Details 
stdClass Object
(
    [pname] => 4-Acetyl-2-chlorobenzonitrile
    [catalogue_number] => PA 04 1941014
    [category_ids] => ,78,70,82,75,76,
    [chemical_name] => 
    [weight] => 179.6
    [form] => C9H6ClNO
    [cas] => 101667-74-7
    [pslug] => 101667-74-7-4-acetyl-2-chlorobenzonitrile-pa041941014
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PA 04 1941014
PA 04 1941014

4-Acetyl-2-chlorobenzonitrile

  • Catalogue No.:PA 04 1941014

  • CAS :

    101667-74-7

  • Molecular Formula : C9H6ClNO

  • Molecular Weight : 179.6

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Details 
stdClass Object
(
    [pname] => tert-Butyl (S)-(1-hydroxypropan-2-yl)carbamate
    [catalogue_number] => PA 04 1941015
    [category_ids] => ,78,70,82,75,76,
    [chemical_name] => 
    [weight] => 175.23
    [form] => C8H17NO3
    [cas] => 79069-13-9
    [pslug] => 79069-13-9-tert-butyl-s-1-hydroxypropan-2-yl-carbamate-pa041941015
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PA 04 1941015
PA 04 1941015

tert-Butyl (S)-(1-hydroxypropan-2-yl)carbamate

  • Catalogue No.:PA 04 1941015

  • CAS :

    79069-13-9

  • Molecular Formula : C8H17NO3

  • Molecular Weight : 175.23

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Details 
stdClass Object
(
    [pname] => Darolutamide R-Isomer
    [catalogue_number] => PA 04 1941016
    [category_ids] => ,78,70,82,75,76,
    [chemical_name] => 
    [weight] => 398.85
    [form] => C19H19ClN6O2
    [cas] => 2407645-49-0
    [pslug] => 2407645-49-0-darolutamide-r-isomer-pa041941016
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PA 04 1941016
PA 04 1941016

Darolutamide R-Isomer

  • Catalogue No.:PA 04 1941016

  • CAS :

    2407645-49-0

  • Molecular Formula : C19H19ClN6O2

  • Molecular Weight : 398.85

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Details 
stdClass Object
(
    [pname] => 2-Chloro-4-(1-((2S)-2-(5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamido)propyl)-1H-pyrazol-3-yl)benzoic Acid
    [catalogue_number] => PA 04 1941017
    [category_ids] => ,78,70,82,75,76,
    [chemical_name] => 
    [weight] => 417.85
    [form] => C19H20ClN5O4
    [cas] => NA
    [pslug] => 2-chloro-4-1-2s-2-5-1-hydroxyethyl-1h-pyrazole-3-carboxamido-propyl-1h-pyrazol-3-yl-benzoic-acid-pa041941017
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PA 04 1941017
PA 04 1941017

2-Chloro-4-(1-((2S)-2-(5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamido)propyl)-1H-pyrazol-3-yl)benzoic Acid

  • Catalogue No.:PA 04 1941017

  • CAS :

    NA

  • Molecular Formula : C19H20ClN5O4

  • Molecular Weight : 417.85

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