chlorambucil
Chlorambucil's current use is mainly in chronic lymphocytic leukemia, as it is well tolerated by most patients, though chlorambucil has been largely replaced by fludarabine as first-line treatment in younger patients.. Reference standards of Chlorambucil API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
stdClass Object
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[pname] => Chlorambucil
[catalogue_number] => PA 03 38000
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[chemical_name] =>
[weight] => 304.21
[form] => C14H19Cl2NO2
[cas] => 305-03-3
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Catalogue No.:PA 03 38000
Molecular Formula : C14H19Cl2NO2
Molecular Weight : 304.21
stdClass Object
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[pname] => D-threo-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
[catalogue_number] => PA 03 38510
[category_ids] => 92,82,80,78,70
[chemical_name] =>
[weight] => 212.2
[form] => C9H12N2O4
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D-threo-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
stdClass Object
(
[pname] => Triphenylphosphine
[catalogue_number] => PA 03 38520
[category_ids] => ,92,80,78,70,82,
[chemical_name] =>
[weight] => 262.29
[form] => C18H15P
[cas] => 603-35-0
[pslug] => 603-35-0-triphenylphosphine-pa0338520
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Catalogue No.:PA 03 38520
Molecular Formula : C18H15P
Molecular Weight : 262.29
stdClass Object
(
[pname] => Chlorambucil-d8
[catalogue_number] => PA STI 018920
[category_ids] => ,70,78,79,80,82,92,98,
[chemical_name] =>
[weight] => 312.26
[form] => C14H11D8Cl2NO2
[cas] => 2733532-57-3
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Catalogue No.:PA STI 018920
Molecular Formula : C14H11D8Cl2NO2
Molecular Weight : 312.26
stdClass Object
(
[pname] => Phenylacetic Mustard
[catalogue_number] => PA 03 0381000
[category_ids] => ,78,75,76,82,
[chemical_name] =>
[weight] => 276.16
[form] => C12H15Cl2NO2
[cas] => 10477-72-2
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Catalogue No.:PA 03 0381000
Molecular Formula : C12H15Cl2NO2
Molecular Weight : 276.16
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(
[pname] => Chlorambucil - Impurity A
[catalogue_number] => PA 03 38010
[category_ids] => ,78,75,70,76,82,
[chemical_name] =>
[weight] => 285.77
[form] => C14H20ClNO3
[cas] => 27171-89-7
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Chlorambucil - Impurity A
Catalogue No.:PA 03 38010
Molecular Formula : C14H20ClNO3
Molecular Weight : 285.77
stdClass Object
(
[pname] => Chlorambucil System Suitability Mixture
[catalogue_number] => PA 03 0381001
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[weight] => NA
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Chlorambucil System Suitability Mixture
stdClass Object
(
[pname] => Ortho-Chlorambucil
[catalogue_number] => PA 03 0381002
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 304.21
[form] => C14H19Cl2NO2
[cas] => 178481-89-5
[pslug] => 178481-89-5-ortho-chlorambucil-pa030381002
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Catalogue No.:PA 03 0381002
Molecular Formula : C14H19Cl2NO2
Molecular Weight : 304.21
stdClass Object
(
[pname] => Meta Chlorambucil
[catalogue_number] => PA 03 0381003
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 304.21
[form] => C14H19Cl2NO2
[cas] => 134862-11-6
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Catalogue No.:PA 03 0381003
Molecular Formula : C14H19Cl2NO2
Molecular Weight : 304.21
stdClass Object
(
[pname] => Methyl 4-(4-(bis(2-chloroethyl)amino)phenyl)butyrate
[catalogue_number] => PA 03 0381004
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[chemical_name] =>
[weight] => 318.24
[form] => C15H21Cl2NO2
[cas] => 79481-83-7
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Methyl 4-(4-(bis(2-chloroethyl)amino)phenyl)butyrate
Catalogue No.:PA 03 0381004
Molecular Formula : C15H21Cl2NO2
Molecular Weight : 318.24
stdClass Object
(
[pname] => 4-(4-(Bis(2-hydroxyethyl)amino)phenyl)butanoic acid
[catalogue_number] => PA 03 0381005
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 267.33
[form] => C14H21NO4
[cas] => 34677-78-6
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4-(4-(Bis(2-hydroxyethyl)amino)phenyl)butanoic acid
Catalogue No.:PA 03 0381005
Molecular Formula : C14H21NO4
Molecular Weight : 267.33
stdClass Object
(
[pname] => 3,4-Dehydro Chlorambucil
[catalogue_number] => PA 03 0381006
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 301.21
[form] => C15H18Cl2O2
[cas] => 73027-06-2
[pslug] => 73027-06-2-3-4-dehydro-chlorambucil-pa030381006
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Catalogue No.:PA 03 0381006
Molecular Formula : C15H18Cl2O2
Molecular Weight : 301.21
stdClass Object
(
[pname] => Chlorambucil ethyl ester
[catalogue_number] => PA 03 0381007
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 332.27
[form] => C16H23Cl2NO2
[cas] => 64977-24-8
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Catalogue No.:PA 03 0381007
Molecular Formula : C16H23Cl2NO2
Molecular Weight : 332.27
stdClass Object
(
[pname] => Chlorambucil isopropyl ester
[catalogue_number] => PA 03 0381008
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 346.29
[form] => C17H25Cl2NO2
[cas] => 77063-20-8
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Chlorambucil isopropyl ester
Catalogue No.:PA 03 0381008
Molecular Formula : C17H25Cl2NO2
Molecular Weight : 346.29
stdClass Object
(
[pname] => 4-(4-Morpholinophenyl)butanoic acid
[catalogue_number] => PA 03 0381009
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 249.31
[form] => C14H19NO3
[cas] => 59826-58-3
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4-(4-Morpholinophenyl)butanoic acid
Catalogue No.:PA 03 0381009
Molecular Formula : C14H19NO3
Molecular Weight : 249.31
stdClass Object
(
[pname] => Chlorambucil - Impurity C
[catalogue_number] => PA 03 0380030
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 490.74
[form] => C18H27Cl3NO6P
[cas] => 2514708-69-9
[pslug] => 2514708-69-9-chlorambucil-impurity-c-pa030380030
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Chlorambucil - Impurity C
Catalogue No.:PA 03 0380030
Molecular Formula : C18H27Cl3NO6P
Molecular Weight : 490.74
stdClass Object
(
[pname] => Chlorambucil - Impurity D
[catalogue_number] => PA 03 0380040
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[chemical_name] =>
[weight] => 366.71
[form] => C16H22Cl3NO2
[cas] => 94236-91-6
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Chlorambucil - Impurity D
Catalogue No.:PA 03 0380040
Molecular Formula : C16H22Cl3NO2
Molecular Weight : 366.71
stdClass Object
(
[pname] => Chlorambucil - Impurity F
[catalogue_number] => PA 03 0380060
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 839.72
[form] => C42H55Cl4N3O6
[cas] => NA
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Chlorambucil - Impurity F
Catalogue No.:PA 03 0380060
Molecular Formula : C42H55Cl4N3O6
Molecular Weight : 839.72
stdClass Object
(
[pname] => 4-(3-Carboxypropyl)-N,N-bis(2-chloroethyl)aniline oxide
[catalogue_number] => PA 03 0381010
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 320.21
[form] => C14H19Cl2NO3
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4-(3-Carboxypropyl)-N,N-bis(2-chloroethyl)aniline oxide
Catalogue No.:PA 03 0381010
Molecular Formula : C14H19Cl2NO3
Molecular Weight : 320.21
stdClass Object
(
[pname] => Chlorambucil - Impurity E
[catalogue_number] => PA 03 38050
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 571.96
[form] => C28H37Cl3N2O4
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Chlorambucil - Impurity E
Catalogue No.:PA 03 38050
Molecular Formula : C28H37Cl3N2O4
Molecular Weight : 571.96