Cangrelor-impurities | Pharmaffiliates

cangrelor

According to recent phase 3 randomized trials, a cangrelor–clopidogrel combination is safe and has been found to be more effective than standard clopidogrel treatment at reducing ischemic events in the heart, without increasing major bleeding in the treatment of stenotic coronary arteries. It is a P2Y12 inhibitor FDA approved as of June 2015 as an antiplatelet drug for intravenous application. Reference standards of Cangrelor API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => Cangrelor Tetrasodium Salt
    [catalogue_number] => PA 30 91570
    [category_ids] => ,80,79,89,88,78,82,
    [chemical_name] => 
    [weight] => 864.29
    [form] => C17H21Cl2F3N5Na4O12P3S2
    [cas] => 163706-36-3
    [pslug] => 163706-36-3-cangrelor-tetrasodium-salt-pa3091570
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PA 30 91570

Cangrelor Tetrasodium Salt


  • Catalogue No.:PA 30 91570

  • CAS :

    163706-36-3

  • Molecular Formula : C17H21Cl2F3N5Na4O12P3S2

  • Molecular Weight : 864.29

stdClass Object
(
    [pname] => ((2R,3S,4R,5R)-3,4-Dihydroxy-5-(6-((2-(methylthio)ethyl)amino)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl hydrogen 1H-imidazol-1-ylphosphonate
    [catalogue_number] => PA 30 91580
    [category_ids] => ,80,79,89,88,78,82,
    [chemical_name] => 
    [weight] => 599.54
    [form] => C19H25F3N7O6PS2
    [cas] => 1054332-15-8
    [pslug] => 1054332-15-8-2r-3s-4r-5r-3-4-dihydroxy-5-6-2-methylthio-ethyl-amino-2-3-3-3-trifluoropropyl-thio-9h-purin-9-yl-tetrahydrofuran-2-yl-methyl-hydrogen-1h-imidazol-1-ylphosphonate-pa3091580
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PA 30 91580

((2R,3S,4R,5R)-3,4-Dihydroxy-5-(6-((2-(methylthio)ethyl)amino)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl hydrogen 1H-imidazol-1-ylphosphonate


  • Catalogue No.:PA 30 91580

  • CAS :

    1054332-15-8

  • Molecular Formula : C19H25F3N7O6PS2

  • Molecular Weight : 599.54

stdClass Object
(
    [pname] => (2R,3R,4R,5R)-2-(6-Acetamido-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)-5-(acetoxymethyl)tetrahydrofuran-3,4-diyl Diacetate
    [catalogue_number] => PA 30 0911000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 563.51
    [form] => C21H24F3N5O8S
    [cas] => 163706-52-3
    [pslug] => 163706-52-3-2r-3r-4r-5r-2-6-acetamido-2-3-3-3-trifluoropropyl-thio-9h-purin-9-yl-5-acetoxymethyl-tetrahydrofuran-3-4-diyl-diacetate-pa300911000
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PA 30 0911000

(2R,3R,4R,5R)-2-(6-Acetamido-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)-5-(acetoxymethyl)tetrahydrofuran-3,4-diyl Diacetate


  • Catalogue No.:PA 30 0911000

  • CAS :

    163706-52-3

  • Molecular Formula : C21H24F3N5O8S

  • Molecular Weight : 563.51

stdClass Object
(
    [pname] => (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(6-(N-(2-(methylthio)ethyl)acetamido)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl Diacetate
    [catalogue_number] => PA 30 0911001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 637.65
    [form] => C24H30F3N5O8S2
    [cas] => 163706-57-8
    [pslug] => 163706-57-8-2r-3r-4r-5r-2-acetoxymethyl-5-6-n-2-methylthio-ethyl-acetamido-2-3-3-3-trifluoropropyl-thio-9h-purin-9-yl-tetrahydrofuran-3-4-diyl-diacetate-pa300911001
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PA 30 0911001

(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(6-(N-(2-(methylthio)ethyl)acetamido)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl Diacetate


  • Catalogue No.:PA 30 0911001

  • CAS :

    163706-57-8

  • Molecular Formula : C24H30F3N5O8S2

  • Molecular Weight : 637.65

stdClass Object
(
    [pname] => Cangrelor Sulfoxide Sodium Salt
    [catalogue_number] => PA 30 0911002
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 880.27
    [form] => C17H21Cl2F3N5Na4O13P3S2
    [cas] => NA
    [pslug] => cangrelor-sulfoxide-sodium-salt-pa300911002
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PA 30 0911002

Cangrelor Sulfoxide Sodium Salt


  • Catalogue No.:PA 30 0911002

  • CAS :

    NA

  • Molecular Formula : C17H21Cl2F3N5Na4O13P3S2

  • Molecular Weight : 880.27

stdClass Object
(
    [pname] => N-Nitroso-Cangrelor
    [catalogue_number] => PA 30 0911005
    [category_ids] => ,162,82,80,79,78,76,75,71,
    [chemical_name] => 
    [weight] => 805.34
    [form] => C17H24Cl2F3N6O13P3S2
    [cas] => NA
    [pslug] => n-nitroso-cangrelor-pa300911005
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PA 30 0911005

N-Nitroso-Cangrelor


  • Catalogue No.:PA 30 0911005

  • CAS :

    NA

  • Molecular Formula : C17H24Cl2F3N6O13P3S2

  • Molecular Weight : 805.34

stdClass Object
(
    [pname] => N-(2-(Methylsulfinyl)ethyl)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-6-amine
    [catalogue_number] => PA 30 0911017
    [category_ids] => ,78,82,70,
    [chemical_name] => 
    [weight] => 353.38
    [form] => C11H14F3N5OS2
    [cas] => 2351938-00-4
    [pslug] => 2351938-00-4-n-2-methylsulfinyl-ethyl-2-3-3-3-trifluoropropyl-thio-9h-purin-6-amine-pa300911017
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PA 30 0911017

N-(2-(Methylsulfinyl)ethyl)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-6-amine


  • Catalogue No.:PA 30 0911017

  • CAS :

    2351938-00-4

  • Molecular Formula : C11H14F3N5OS2

  • Molecular Weight : 353.38

stdClass Object
(
    [pname] => Cangrelor Monophosphoryl Dimer Impurity
    [catalogue_number] => PA 30 0911018
    [category_ids] => ,78,82,70,
    [chemical_name] => 
    [weight] => 1080.9
    [form] => C32H44F6N10O13P2S4
    [cas] => NA
    [pslug] => cangrelor-monophosphoryl-dimer-impurity-pa300911018
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PA 30 0911018

Cangrelor Monophosphoryl Dimer Impurity


  • Catalogue No.:PA 30 0911018

  • CAS :

    NA

  • Molecular Formula : C32H44F6N10O13P2S4

  • Molecular Weight : 1080.9