Binimetinib-impurities | Pharmaffiliates

Binimetinib

Binimetinib, also known as Mektovi and ARRY-162. It is used to treat a type of skin cancer.Reference standards of Binimetinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Binimetinib - API Standards 
    [catalogue_number] => PA 02 1850000
    [category_ids] => ,123,81,78,75,76,82,
    [chemical_name] => 
    [weight] => 441.23
    [form] => C17H15BrF2N4O3
    [cas] => 606143-89-9
    [pslug] => 606143-89-9-binimetinib-pa021850000
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PA 02 1850000

Binimetinib - API Standards


  • Catalogue No.:PA 02 1850000

  • CAS :

    606143-89-9

  • Molecular Formula : C17H15BrF2N4O3

  • Molecular Weight : 441.23

stdClass Object
(
    [pname] => Methyl 4-amino-2,3-difluoro-5-nitrobenzoate
    [catalogue_number] => PA 02 1851002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 232.14
    [form] => C8H6F2N2O4
    [cas] => 284030-58-6
    [pslug] => 284030-58-6-methyl-4-amino-2-3-difluoro-5-nitrobenzoate-pa021851002
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PA 02 1851002

Methyl 4-amino-2,3-difluoro-5-nitrobenzoate


  • Catalogue No.:PA 02 1851002

  • CAS :

    284030-58-6

  • Molecular Formula : C8H6F2N2O4

  • Molecular Weight : 232.14

stdClass Object
(
    [pname] => Binimetinib Glucuronide
    [catalogue_number] => PA 02 1851003
    [category_ids] => ,70,75,76,78,82,95,
    [chemical_name] => 
    [weight] => 617.36
    [form] => C23H23BrF2N4O9
    [cas] => NA
    [pslug] => binimetinib-glucuronide-pa021851003
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PA 02 1851003

Binimetinib Glucuronide


  • Catalogue No.:PA 02 1851003

  • CAS :

    NA

  • Molecular Formula : C23H23BrF2N4O9

  • Molecular Weight : 617.36

stdClass Object
(
    [pname] => Binimetinib Dimer Impurity
    [catalogue_number] => PA 02 1851004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 614.22
    [form] => C23H17Br2F3N4O3
    [cas] => NA
    [pslug] => binimetinib-dimer-impurity-pa021851004
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PA 02 1851004

Binimetinib Dimer Impurity


  • Catalogue No.:PA 02 1851004

  • CAS :

    NA

  • Molecular Formula : C23H17Br2F3N4O3

  • Molecular Weight : 614.22

stdClass Object
(
    [pname] => Binimetinib Amide Impurity
    [catalogue_number] => PA 02 1851005
    [category_ids] => ,123,81,78,75,76,82,
    [chemical_name] => 
    [weight] => 497.34
    [form] => C21H23BrF2N4O3
    [cas] => 1604812-70-5
    [pslug] => 1604812-70-5-binimetinib-amide-impurity-pa021851005
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PA 02 1851005

Binimetinib Amide Impurity


  • Catalogue No.:PA 02 1851005

  • CAS :

    1604812-70-5

  • Molecular Formula : C21H23BrF2N4O3

  • Molecular Weight : 497.34

stdClass Object
(
    [pname] => Binimetinib Methyl Ester Impurity
    [catalogue_number] => PA 02 1851006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 396.19
    [form] => C16H12BrF2N3O2
    [cas] => 1415559-93-1
    [pslug] => 1415559-93-1-binimetinib-methyl-ester-impurity-pa021851006
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PA 02 1851006

Binimetinib Methyl Ester Impurity


  • Catalogue No.:PA 02 1851006

  • CAS :

    1415559-93-1

  • Molecular Formula : C16H12BrF2N3O2

  • Molecular Weight : 396.19

stdClass Object
(
    [pname] => 5-((4-Bromo-2-fluorophenyl)amino)-N'-(5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carbonyl)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carbohydrazide
    [catalogue_number] => PA 02 1851007
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 760.35
    [form] => C30H20Br2F4N8O2
    [cas] => NA
    [pslug] => 5-4-bromo-2-fluorophenyl-amino-n-5-4-bromo-2-fluorophenyl-amino-4-fluoro-1-methyl-1h-benzo-d-imidazole-6-carbonyl-4-fluoro-1-methyl-1h-benzo-d-imidazole-6-carbohydrazide-pa021851007
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PA 02 1851007

5-((4-Bromo-2-fluorophenyl)amino)-N'-(5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carbonyl)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carbohydrazide


  • Catalogue No.:PA 02 1851007

  • CAS :

    NA

  • Molecular Formula : C30H20Br2F4N8O2

  • Molecular Weight : 760.35

stdClass Object
(
    [pname] => N-(2-(Aminooxy)ethoxy)-5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxamide
    [catalogue_number] => PA 02 1851008
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 456.25
    [form] => C17H16BrF2N5O3
    [cas] => NA
    [pslug] => n-2-aminooxy-ethoxy-5-4-bromo-2-fluorophenyl-amino-4-fluoro-1-methyl-1h-benzo-d-imidazole-6-carboxamide-pa021851008
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PA 02 1851008

N-(2-(Aminooxy)ethoxy)-5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxamide


  • Catalogue No.:PA 02 1851008

  • CAS :

    NA

  • Molecular Formula : C17H16BrF2N5O3

  • Molecular Weight : 456.25

stdClass Object
(
    [pname] => N,N'-(Ethane-1,2-diylbis(oxy))bis(5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxamide)
    [catalogue_number] => PA 02 1851009
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 820.4
    [form] => C32H24Br2F4N8O4
    [cas] => NA
    [pslug] => n-n-ethane-1-2-diylbis-oxy-bis-5-4-bromo-2-fluorophenyl-amino-4-fluoro-1-methyl-1h-benzo-d-imidazole-6-carboxamide-pa021851009
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PA 02 1851009

N,N'-(Ethane-1,2-diylbis(oxy))bis(5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxamide)


  • Catalogue No.:PA 02 1851009

  • CAS :

    NA

  • Molecular Formula : C32H24Br2F4N8O4

  • Molecular Weight : 820.4

stdClass Object
(
    [pname] => 1,3-Dioxoisoindolin-2-yl 5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylate
    [catalogue_number] => PA 02 1851010
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 527.28
    [form] => C23H13BrF2N4O4
    [cas] => NA
    [pslug] => 1-3-dioxoisoindolin-2-yl-5-4-bromo-2-fluorophenyl-amino-4-fluoro-1-methyl-1h-benzo-d-imidazole-6-carboxylate-pa021851010
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PA 02 1851010

1,3-Dioxoisoindolin-2-yl 5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylate


  • Catalogue No.:PA 02 1851010

  • CAS :

    NA

  • Molecular Formula : C23H13BrF2N4O4

  • Molecular Weight : 527.28

stdClass Object
(
    [pname] => 1-(4-Bromo-2-fluorophenyl)-8-fluoro-5-methyl-1,5-dihydro-3H-imidazo[4',5':4,5]benzo[1,2-c]isoxazol-3-one
    [catalogue_number] => PA 02 1851011
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 380.15
    [form] => C15H8BrF2N3O2
    [cas] => NA
    [pslug] => 1-4-bromo-2-fluorophenyl-8-fluoro-5-methyl-1-5-dihydro-3h-imidazo-4-5-4-5-benzo-1-2-c-isoxazol-3-one-pa021851011
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PA 02 1851011

1-(4-Bromo-2-fluorophenyl)-8-fluoro-5-methyl-1,5-dihydro-3H-imidazo[4',5':4,5]benzo[1,2-c]isoxazol-3-one


  • Catalogue No.:PA 02 1851011

  • CAS :

    NA

  • Molecular Formula : C15H8BrF2N3O2

  • Molecular Weight : 380.15

stdClass Object
(
    [pname] => Ethyl 5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylate
    [catalogue_number] => PA 02 1851012
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 410.22
    [form] => C17H14BrF2N3O2
    [cas] => 2509103-99-3
    [pslug] => 2509103-99-3-ethyl-5-4-bromo-2-fluorophenyl-amino-4-fluoro-1-methyl-1h-benzo-d-imidazole-6-carboxylate-pa021851012
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PA 02 1851012

Ethyl 5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylate


  • Catalogue No.:PA 02 1851012

  • CAS :

    2509103-99-3

  • Molecular Formula : C17H14BrF2N3O2

  • Molecular Weight : 410.22

stdClass Object
(
    [pname] => N-Desmethyl Binimetinib
    [catalogue_number] => PA 02 1851013
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 427.21
    [form] => C16H13BrF2N4O3
    [cas] => NA
    [pslug] => n-desmethyl-binimetinib-pa021851013
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PA 02 1851013

N-Desmethyl Binimetinib


  • Catalogue No.:PA 02 1851013

  • CAS :

    NA

  • Molecular Formula : C16H13BrF2N4O3

  • Molecular Weight : 427.21

stdClass Object
(
    [pname] => Binimetinib-D3
    [catalogue_number] => PA STI 089454
    [category_ids] => ,98,123,81,78,75,76,82,
    [chemical_name] => 
    [weight] => 444.25
    [form] => C17H12D3BrF2N4O3
    [cas] => NA
    [pslug] => binimetinib-d3-pasti089454
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PA STI 089454

Binimetinib-D3


  • Catalogue No.:PA STI 089454

  • CAS :

    NA

  • Molecular Formula : C17H12D3BrF2N4O3

  • Molecular Weight : 444.25

stdClass Object
(
    [pname] => Binimetinib Acid Nitroso Impurity
    [catalogue_number] => PA 02 1851014
    [category_ids] => ,123,81,78,75,76,82,162,
    [chemical_name] => 
    [weight] => 411.16
    [form] => C15H9BrF2N4O3
    [cas] => NA
    [pslug] => binimetinib-acid-nitroso-impurity-pa021851014
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PA 02 1851014

Binimetinib Acid Nitroso Impurity


  • Catalogue No.:PA 02 1851014

  • CAS :

    NA

  • Molecular Formula : C15H9BrF2N4O3

  • Molecular Weight : 411.16

stdClass Object
(
    [pname] => Binimetinib Methyl Ester Nitroso Impurity
    [catalogue_number] => PA 02 1851015
    [category_ids] => ,123,81,78,75,76,82,162,
    [chemical_name] => 
    [weight] => 425.19
    [form] => C16H11BrF2N4O3
    [cas] => NA
    [pslug] => binimetinib-methyl-ester-nitroso-impurity-pa021851015
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PA 02 1851015

Binimetinib Methyl Ester Nitroso Impurity


  • Catalogue No.:PA 02 1851015

  • CAS :

    NA

  • Molecular Formula : C16H11BrF2N4O3

  • Molecular Weight : 425.19

stdClass Object
(
    [pname] => Binimetinib Nitroso Amide Impurity
    [catalogue_number] => PA 02 1851016
    [category_ids] => ,123,81,78,75,76,82,162,
    [chemical_name] => 
    [weight] => 526.34
    [form] => C21H22BrF2N5O4
    [cas] => NA
    [pslug] => binimetinib-nitroso-amide-impurity-pa021851016
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PA 02 1851016

Binimetinib Nitroso Amide Impurity


  • Catalogue No.:PA 02 1851016

  • CAS :

    NA

  • Molecular Formula : C21H22BrF2N5O4

  • Molecular Weight : 526.34

stdClass Object
(
    [pname] => 5-((4-Bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-N-(2-(vinyloxy)ethoxy)-1H-benzo[d]imidazole-6-carboxamide
    [catalogue_number] => PA 02 1851017
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 467.27
    [form] => C19H17BrF2N4O3
    [cas] => 1415559-75-9
    [pslug] => 1415559-75-9-5-4-bromo-2-fluorophenyl-amino-4-fluoro-1-methyl-n-2-vinyloxy-ethoxy-1h-benzo-d-imidazole-6-carboxamide-pa021851017
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PA 02 1851017

5-((4-Bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-N-(2-(vinyloxy)ethoxy)-1H-benzo[d]imidazole-6-carboxamide


  • Catalogue No.:PA 02 1851017

  • CAS :

    1415559-75-9

  • Molecular Formula : C19H17BrF2N4O3

  • Molecular Weight : 467.27

stdClass Object
(
    [pname] => Binimetinib Des Ethanediol Impurity
    [catalogue_number] => PA 02 1851018
    [category_ids] => ,123,81,78,75,76,82,
    [chemical_name] => 
    [weight] => 381.18
    [form] => C15H11BrF2N4O
    [cas] => 2851526-50-4
    [pslug] => 2851526-50-4-binimetinib-des-ethanediol-impurity-pa021851018
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PA 02 1851018

Binimetinib Des Ethanediol Impurity


  • Catalogue No.:PA 02 1851018

  • CAS :

    2851526-50-4

  • Molecular Formula : C15H11BrF2N4O

  • Molecular Weight : 381.18

stdClass Object
(
    [pname] => Binimetinib Des Bromo Impurity
    [catalogue_number] => PA 02 1851019
    [category_ids] => ,123,81,78,75,76,82,
    [chemical_name] => 
    [weight] => 362.34
    [form] => C17H16F2N4O3
    [cas] => NA
    [pslug] => binimetinib-des-bromo-impurity-pa021851019
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PA 02 1851019

Binimetinib Des Bromo Impurity


  • Catalogue No.:PA 02 1851019

  • CAS :

    NA

  • Molecular Formula : C17H16F2N4O3

  • Molecular Weight : 362.34

stdClass Object
(
    [pname] => 4-Fluoro-5-((2-fluorophenyl)amino)-1-methyl-1H-benzo[d]imidazole-6-carboxylic Acid
    [catalogue_number] => PA 02 1851020
    [category_ids] => ,123,81,78,75,76,82,
    [chemical_name] => 
    [weight] => 303.27
    [form] => C15H11F2N3O2
    [cas] => 2649854-87-3
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PA 02 1851020

4-Fluoro-5-((2-fluorophenyl)amino)-1-methyl-1H-benzo[d]imidazole-6-carboxylic Acid


  • Catalogue No.:PA 02 1851020

  • CAS :

    2649854-87-3

  • Molecular Formula : C15H11F2N3O2

  • Molecular Weight : 303.27

stdClass Object
(
    [pname] => 4-Fluoro-5-((2-fluorophenyl)amino)-1-methyl-N-(2-(vinyloxy)ethoxy)-1H-benzo[d]imidazole-6-carboxamide
    [catalogue_number] => PA 02 1851021
    [category_ids] => ,123,81,78,75,76,82,
    [chemical_name] => 
    [weight] => 388.37
    [form] => C19H18F2N4O3
    [cas] => 2649854-88-4
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PA 02 1851021

4-Fluoro-5-((2-fluorophenyl)amino)-1-methyl-N-(2-(vinyloxy)ethoxy)-1H-benzo[d]imidazole-6-carboxamide


  • Catalogue No.:PA 02 1851021

  • CAS :

    2649854-88-4

  • Molecular Formula : C19H18F2N4O3

  • Molecular Weight : 388.37

stdClass Object
(
    [pname] => 5-((4-Bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylic Acid
    [catalogue_number] => PA 02 1851022
    [category_ids] => ,123,81,78,75,76,82,
    [chemical_name] => 
    [weight] => 382.16
    [form] => C15H10BrF2N3O2
    [cas] => NA
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PA 02 1851022

5-((4-Bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylic Acid


  • Catalogue No.:PA 02 1851022

  • CAS :

    NA

  • Molecular Formula : C15H10BrF2N3O2

  • Molecular Weight : 382.16

stdClass Object
(
    [pname] => 5-((4-Bromo-2-fluorophenyl)amino)-N-(2-ethoxyethoxy)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxamide
    [catalogue_number] => PA 02 1851023
    [category_ids] => ,123,81,78,75,76,82,
    [chemical_name] => 
    [weight] => 469.29
    [form] => C19H19BrF2N4O3
    [cas] => NA
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PA 02 1851023

5-((4-Bromo-2-fluorophenyl)amino)-N-(2-ethoxyethoxy)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxamide


  • Catalogue No.:PA 02 1851023

  • CAS :

    NA

  • Molecular Formula : C19H19BrF2N4O3

  • Molecular Weight : 469.29

stdClass Object
(
    [pname] => N-Nitroso Binimetinib
    [catalogue_number] => PA 02 1851024
    [category_ids] => ,79,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 470.23
    [form] =>  C17H14BrF2N5O4
    [cas] => NA
    [pslug] => n-nitroso-binimetinib-pa021851024
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PA 02 1851024

N-Nitroso Binimetinib


  • Catalogue No.:PA 02 1851024

  • CAS :

    NA

  • Molecular Formula : C17H14BrF2N5O4

  • Molecular Weight : 470.23

stdClass Object
(
    [pname] => Binimetinib Acid Impurity
    [catalogue_number] => PA 02 1851025
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 382.16
    [form] => C15H10BrF2N3O2
    [cas] => 1415564-99-6
    [pslug] => 1415564-99-6-binimetinib-acid-impurity-pa021851025
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PA 02 1851025

Binimetinib Acid Impurity


  • Catalogue No.:PA 02 1851025

  • CAS :

    1415564-99-6

  • Molecular Formula : C15H10BrF2N3O2

  • Molecular Weight : 382.16

stdClass Object
(
    [pname] => 5-(4-Bromo-2-fluorophenyl)-4-fluoro-7-(2-hydroxyethoxy)-1,6-dimethyl-1,5,6,7-tetrahydro-8H-imidazo[4,5-g]quinazolin-8-one
    [catalogue_number] => PA 02 1851026
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 467.27
    [form] => C19H17BrF2N4O3
    [cas] => NA
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PA 02 1851026

5-(4-Bromo-2-fluorophenyl)-4-fluoro-7-(2-hydroxyethoxy)-1,6-dimethyl-1,5,6,7-tetrahydro-8H-imidazo[4,5-g]quinazolin-8-one


  • Catalogue No.:PA 02 1851026

  • CAS :

    NA

  • Molecular Formula : C19H17BrF2N4O3

  • Molecular Weight : 467.27

stdClass Object
(
    [pname] => 2-((5-((4-Bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxamido)oxy)ethyl acetate
    [catalogue_number] => PA 02 1851027
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 483.27
    [form] => C19H17BrF2N4O4
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PA 02 1851027

2-((5-((4-Bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxamido)oxy)ethyl acetate


  • Catalogue No.:PA 02 1851027

  • CAS :

    NA

  • Molecular Formula : C19H17BrF2N4O4

  • Molecular Weight : 483.27

stdClass Object
(
    [pname] => 2,4-Diamino-3-fluoro-5-nitrobenzoic Acid
    [catalogue_number] => PA 02 1851028
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 215.14
    [form] => C7H6FN3O4
    [cas] => 918321-31-0
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PA 02 1851028

2,4-Diamino-3-fluoro-5-nitrobenzoic Acid


  • Catalogue No.:PA 02 1851028

  • CAS :

    918321-31-0

  • Molecular Formula : C7H6FN3O4

  • Molecular Weight : 215.14