Apalutamide
Apalutamide, sold under the brand name Erleada among others, is a nonsteroidal antiandrogen medication which is used in the treatment of prostate cancer. It is specifically indicated for use in conjunction with castration in the treatment of non-metastatic castration-resistant prostate cancer Reference standards of Apalutamide API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
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[pname] => Apalutamide
[catalogue_number] => PA 01 2920000
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[chemical_name] =>
[weight] => 477.44
[form] => C21H15F4N5O2S
[cas] => 956104-40-8
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Catalogue No.:PA 01 2920000
Molecular Formula : C21H15F4N5O2S
Molecular Weight : 477.44
stdClass Object
(
[pname] => 4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzamide
[catalogue_number] => PA 01 2921000
[category_ids] => ,70,75,76,78,82,
[chemical_name] =>
[weight] => 463.41
[form] => C20H13F4N5O2S
[cas] => 1332391-11-3
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4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzamide
Catalogue No.:PA 01 2921000
Molecular Formula : C20H13F4N5O2S
Molecular Weight : 463.41
stdClass Object
(
[pname] => 4-((1-Cyanocyclobutyl)amino)-2-fluoro-N-methylbenzamide
[catalogue_number] => PA 01 2921004
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[chemical_name] =>
[weight] => 247.27
[form] => C13H14FN3O
[cas] => 915087-26-2
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4-((1-Cyanocyclobutyl)amino)-2-fluoro-N-methylbenzamide
Catalogue No.:PA 01 2921004
Molecular Formula : C13H14FN3O
Molecular Weight : 247.27
stdClass Object
(
[pname] => 4-((1-((6-Cyano-5-(trifluoromethyl)pyridin-3-yl)carbamoyl)cyclobutyl)amino)-2-fluoro-N-methylbenzamide
[catalogue_number] => PA 01 2921005
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[chemical_name] =>
[weight] => 435.38
[form] => C20H17F4N5O2
[cas] => 1950587-20-8
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4-((1-((6-Cyano-5-(trifluoromethyl)pyridin-3-yl)carbamoyl)cyclobutyl)amino)-2-fluoro-N-methylbenzamide
Catalogue No.:PA 01 2921005
Molecular Formula : C20H17F4N5O2
Molecular Weight : 435.38
stdClass Object
(
[pname] => 1-[3-Fluoro-4-(methylcarbamoyl)anilino]cyclobutane-1-carboxylic acid
[catalogue_number] => PA 01 2921006
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[chemical_name] =>
[weight] => 266.27
[form] => C13H15FN2O3
[cas] => 2227589-22-0
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1-[3-Fluoro-4-(methylcarbamoyl)anilino]cyclobutane-1-carboxylic acid
Catalogue No.:PA 01 2921006
Molecular Formula : C13H15FN2O3
Molecular Weight : 266.27
stdClass Object
(
[pname] => 1-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)thiourea
[catalogue_number] => PA 01 2921007
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[chemical_name] =>
[weight] => 246.21
[form] => C8H5F3N4S
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1-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)thiourea
Catalogue No.:PA 01 2921007
Molecular Formula : C8H5F3N4S
Molecular Weight : 246.21
stdClass Object
(
[pname] => 4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3,4]octan-5-yl)-2-fluorobenzoic acid
[catalogue_number] => PA 01 2921008
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[weight] => 464.39
[form] => C20H12F4N4O3S
[cas] => 1332391-04-4
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4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3,4]octan-5-yl)-2-fluorobenzoic acid
Catalogue No.:PA 01 2921008
Molecular Formula : C20H12F4N4O3S
Molecular Weight : 464.39
stdClass Object
(
[pname] => Apalutamide D3
[catalogue_number] => PA STI 088917
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[weight] => 480.46
[form] => C21H12D3F4N5O2S
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Catalogue No.:PA STI 088917
Molecular Formula : C21H12D3F4N5O2S
Molecular Weight : 480.46
stdClass Object
(
[pname] => 4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-(methyl-13C-d3)benzamide
[catalogue_number] => PA STI 088918
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[chemical_name] =>
[weight] => 481.45
[form] => C2013CH12D3F4N5O2S
[cas] => NA
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4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-(methyl-13C-d3)benzamide
Catalogue No.:PA STI 088918
Molecular Formula : C2013CH12D3F4N5O2S
Molecular Weight : 481.45
stdClass Object
(
[pname] => 4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-N-methylbenzamide
[catalogue_number] => PA 01 2921009
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[chemical_name] =>
[weight] => 459.45
[form] => C21H16F3N5O2S
[cas] => 1332389-57-7
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4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-N-methylbenzamide
Catalogue No.:PA 01 2921009
Molecular Formula : C21H16F3N5O2S
Molecular Weight : 459.45
stdClass Object
(
[pname] => 2-Fluoro-4-(hydroxyamino)-N-methylbenzamide
[catalogue_number] => PA 01 2921010
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 184.17
[form] => C8H9FN2O2
[cas] => NA
[pslug] => 2-fluoro-4-hydroxyamino-n-methylbenzamide-pa012921010
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2-Fluoro-4-(hydroxyamino)-N-methylbenzamide
Catalogue No.:PA 01 2921010
Molecular Formula : C8H9FN2O2
Molecular Weight : 184.17
stdClass Object
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[pname] => 2-Bromo-5-Nitro-3-(Trifluoromethyl)Pyridine
[catalogue_number] => PA 01 2921012
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[weight] => 270.99
[form] => C6H2BrF3N2O2
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2-Bromo-5-Nitro-3-(Trifluoromethyl)Pyridine
Catalogue No.:PA 01 2921012
Molecular Formula : C6H2BrF3N2O2
Molecular Weight : 270.99
stdClass Object
(
[pname] => 4-Amino-N-methylbenzamide
[catalogue_number] => PA 01 2921013
[category_ids] => ,75,76,78,70,82,
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[weight] => 150.18
[form] => C8H10N2O
[cas] => 6274-22-2
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4-Amino-N-methylbenzamide
Catalogue No.:PA 01 2921013
Molecular Formula : C8H10N2O
Molecular Weight : 150.18
stdClass Object
(
[pname] => 2-Fluoro-4-nitrotoluene
[catalogue_number] => PA 01 2921014
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 155.13
[form] => C7H6FNO2
[cas] => 1427-07-2
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Catalogue No.:PA 01 2921014
Molecular Formula : C7H6FNO2
Molecular Weight : 155.13
stdClass Object
(
[pname] => 4-Amino-2-fluorobenzoic Acid
[catalogue_number] => PA 01 2921015
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[weight] => 155.13
[form] => C7H6FNO2
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4-Amino-2-fluorobenzoic Acid
Catalogue No.:PA 01 2921015
Molecular Formula : C7H6FNO2
Molecular Weight : 155.13
stdClass Object
(
[pname] => O-Phenyl (4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoyl)(methyl)carbamothioate
[catalogue_number] => PA 01 2921017
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[chemical_name] =>
[weight] => 613.61
[form] => C28H19F4N5O3S2
[cas] => NA
[pslug] => o-phenyl-4-7-6-cyano-5-trifluoromethyl-pyridin-3-yl-8-oxo-6-thioxo-5-7-diazaspiro-3-4-octan-5-yl-2-fluorobenzoyl-methyl-carbamothioate-pa012921017
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O-Phenyl (4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoyl)(methyl)carbamothioate
Catalogue No.:PA 01 2921017
Molecular Formula : C28H19F4N5O3S2
Molecular Weight : 613.61
stdClass Object
(
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[catalogue_number] => PA 01 2921016
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 881.76
[form] => C40H27F8N9O4S
[cas] => NA
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4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-N-(1-((6-cyano-5-(trifluoromethyl)pyridin-3-yl)carbamoyl)cyclobutyl)-2-fluoro-N-(3-fluoro-4-(methylcarbamoyl)phenyl)benzamide
Catalogue No.:PA 01 2921016
Molecular Formula : C40H27F8N9O4S
Molecular Weight : 881.76
stdClass Object
(
[pname] => 1-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)Cyclobutane-1-Carboxylic Acid, Potassium Salt (1:1)
[catalogue_number] => PA 01 2921018
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[chemical_name] =>
[weight] => 304.36
[form] => C13H14FKN2O3
[cas] => 2408380-71-0
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1-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)Cyclobutane-1-Carboxylic Acid, Potassium Salt (1:1)
Catalogue No.:PA 01 2921018
Molecular Formula : C13H14FKN2O3
Molecular Weight : 304.36
stdClass Object
(
[pname] => Sodium 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate
[catalogue_number] => PA 01 2921019
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[weight] => 486.38
[form] => C20H11F4N4NaO3S
[cas] => NA
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Sodium 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate
Catalogue No.:PA 01 2921019
Molecular Formula : C20H11F4N4NaO3S
Molecular Weight : 486.38
stdClass Object
(
[pname] => Methyl 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate
[catalogue_number] => PA 01 2921020
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[weight] => 478.42
[form] => C21H14F4N4O3S
[cas] => 1950587-19-5
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Methyl 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate
Catalogue No.:PA 01 2921020
Molecular Formula : C21H14F4N4O3S
Molecular Weight : 478.42
stdClass Object
(
[pname] => Ethyl 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate
[catalogue_number] => PA 01 2921021
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 492.45
[form] => C22H16F4N4O3S
[cas] => 1332388-83-6
[pslug] => 1332388-83-6-ethyl-4-7-6-cyano-5-trifluoromethyl-pyridin-3-yl-8-oxo-6-thioxo-5-7-diazaspiro-3-4-octan-5-yl-2-fluorobenzoate-pa012921021
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Ethyl 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate
Catalogue No.:PA 01 2921021
Molecular Formula : C22H16F4N4O3S
Molecular Weight : 492.45
stdClass Object
(
[pname] => 1-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)urea
[catalogue_number] => PA 01 2921022
[category_ids] => ,75,76,78,82,
[chemical_name] =>
[weight] => 230.15
[form] => C8H5F3N4O
[cas] => NA
[pslug] => 1-6-cyano-5-trifluoromethyl-pyridin-3-yl-urea-pa012921022
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1-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)urea
Catalogue No.:PA 01 2921022
Molecular Formula : C8H5F3N4O
Molecular Weight : 230.15
stdClass Object
(
[pname] => 4-((1-Cyanocyclobutyl)(nitroso)amino)-2-fluoro-N-methylbenzamide
[catalogue_number] => PA 01 2921023
[category_ids] => ,70,75,76,78,82,162,
[chemical_name] =>
[weight] => 276.27
[form] => C13H13FN4O2
[cas] => NA
[pslug] => 4-1-cyanocyclobutyl-nitroso-amino-2-fluoro-n-methylbenzamide-pa012921023
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4-((1-Cyanocyclobutyl)(nitroso)amino)-2-fluoro-N-methylbenzamide
Catalogue No.:PA 01 2921023
Molecular Formula : C13H13FN4O2
Molecular Weight : 276.27
stdClass Object
(
[pname] => 4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-(3-fluoro-4-(methylcarbamoyl)phenyl)-N-methylbenzamide
[catalogue_number] => PA 01 2921024
[category_ids] => 76,82,78,70,75
[chemical_name] =>
[weight] => 628.58
[form] => C29H21F5N6O3S
[cas] => 2894796-76-8
[pslug] => 2894796-76-8-4-7-6-cyano-5-trifluoromethyl-pyridin-3-yl-8-oxo-6-thioxo-5-7-diazaspiro-3-4-octan-5-yl-2-fluoro-n-3-fluoro-4-methylcarbamoyl-phenyl-n-methylbenzamide-pa012921024
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4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-(3-fluoro-4-(methylcarbamoyl)phenyl)-N-methylbenzamide
Catalogue No.:PA 01 2921024
Molecular Formula : C29H21F5N6O3S
Molecular Weight : 628.58
