Ambrisentan is a drug indicated for use in the treatment of pulmonary hypertension. Ambrisentan was approved by the U.S. Food and Drug Administration (FDA) and European Medicines Agency, and designated an orphan drug, for the treatment of pulmonary hypertension. Reference standards of Ambrisentan API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => Ambrisentan Vinyloxy Impurity [catalogue_number] => PA 28 46550 [category_ids] => ,80,71,75,78,70,82, [chemical_name] => [weight] => 302.37 [form] => C20H18N2O [cas] => 1639429-81-4 [pslug] => 1639429-81-4-ambrisentan-vinyloxy-impurity-pa2846550 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 46550
CAS :
Molecular Formula : C20H18N2O
Molecular Weight : 302.37
stdClass Object ( [pname] => (R)-Ambrisentan [catalogue_number] => PA 28 46560 [category_ids] => ,80,75,78,70,82, [chemical_name] => [weight] => 378.16 [form] => C22H22N2O4 [cas] => 1007358-76-0 [pslug] => 1007358-76-0-r-ambrisentan-pa2846560 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 46560
Molecular Formula : C22H22N2O4
Molecular Weight : 378.16
stdClass Object ( [pname] => 3,3-Diphenyl-oxiranecarboxylic Acid Methyl Ester [catalogue_number] => PA 28 46570 [category_ids] => ,71,78,70,82, [chemical_name] => [weight] => 254.28 [form] => C16H14O3 [cas] => 76527-25-8 [pslug] => 76527-25-8-3-3-diphenyl-oxiranecarboxylic-acid-methyl-ester-pa2846570 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 46570
Molecular Formula : C16H14O3
Molecular Weight : 254.28
stdClass Object ( [pname] => rac Ambrisentan-d3 [catalogue_number] => PA STI 005030 [category_ids] => ,80,71,78,70,82,98, [chemical_name] => [weight] => 381.44 [form] => C22H19D3N2O4 [cas] => 1189479-60-4 [pslug] => 1189479-60-4-rac-ambrisentan-d3-pasti005030 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 005030
Molecular Formula : C22H19D3N2O4
Molecular Weight : 381.44
stdClass Object ( [pname] => rac Ambrisentan-d3 Methyl Ester [catalogue_number] => PA STI 005040 [category_ids] => ,80,78,70,82,98, [chemical_name] => [weight] => 395.47 [form] => C23H21D3N2O4 [cas] => 1329837-75-3 [pslug] => 1329837-75-3-rac-ambrisentan-d3-methyl-ester-pasti005040 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 005040
Molecular Formula : C23H21D3N2O4
Molecular Weight : 395.47
stdClass Object ( [pname] => 4,6-Dimethoxy-β-methyl-3-phenoxy Ambrisentan-d5 [catalogue_number] => PA STI 033300 [category_ids] => ,80,71,78,70,82,98, [chemical_name] => [weight] => 415.45 [form] => C22H17D5N2O6 [cas] => 1346597-40-7 [pslug] => 1346597-40-7-4-6-dimethoxy-beta-methyl-3-phenoxy-ambrisentan-d5-pasti033300 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 033300
Molecular Formula : C22H17D5N2O6
Molecular Weight : 415.45
stdClass Object ( [pname] => 2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid-d3 Methyl Ester [catalogue_number] => PA STI 049730 [category_ids] => ,80,98,78,70,82, [chemical_name] => [weight] => 289.34 [form] => C17H15D3O4 [cas] => 1046116-52-2 [pslug] => 1046116-52-2-2-hydroxy-3-methoxy-3-3-diphenylpropanoic-acid-d3-methyl-ester-pasti049730 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 049730
Molecular Formula : C17H15D3O4
Molecular Weight : 289.34
stdClass Object ( [pname] => rac 4-Hydroxymethyl Ambrisentan-d3 [catalogue_number] => PA STI 050030 [category_ids] => ,80,71,98,76,75,78,70,82, [chemical_name] => [weight] => 397.44 [form] => C22H19D3N2O5 [cas] => 1287096-42-7 [pslug] => 1287096-42-7-rac-4-hydroxymethyl-ambrisentan-d3-pasti050030 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 050030
Molecular Formula : C22H19D3N2O5
Molecular Weight : 397.44
stdClass Object ( [pname] => rac Ambrisentan Methyl Ester [catalogue_number] => PA 28 46600 [category_ids] => ,80,78,70,82, [chemical_name] => [weight] => 392.45 [form] => C23H24N2O4 [cas] => 1240470-84-1 [pslug] => 1240470-84-1-rac-ambrisentan-methyl-ester-pa2846600 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 46600
Molecular Formula : C23H24N2O4
Molecular Weight : 392.45
stdClass Object ( [pname] => Ambrisentan Acyl β-D-Glucuronide [catalogue_number] => PA 28 46610 [category_ids] => ,80,95,71,76,75,78,70,82, [chemical_name] => [weight] => 554.55 [form] => C28H30N20O10 [cas] => 1106685-58-8 [pslug] => 1106685-58-8-ambrisentan-acyl-beta-d-glucuronide-pa2846610 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 46610
Molecular Formula : C28H30N20O10
Molecular Weight : 554.55
stdClass Object ( [pname] => Ambrisentan Pyrimidine Ester Impurity [catalogue_number] => PA 28 46620 [category_ids] => ,78,70,82, [chemical_name] => [weight] => 392.46 [form] => C23H24N2O4 [cas] => NA [pslug] => ambrisentan-pyrimidine-ester-impurity-pa2846620 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 46620
Molecular Weight : 392.46
stdClass Object ( [pname] => 2,3-Dihydroxy-3,3-diphenylpropionic Acid Methyl Ester [catalogue_number] => PA 28 0461000 [category_ids] => ,75,76,78,82, [chemical_name] => [weight] => 272.3 [form] => C16H16O4 [cas] => NA [pslug] => -2-3-dihydroxy-3-3-diphenylpropionic-acid-methyl-ester-pa280461000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0461000
Molecular Formula : C16H16O4
Molecular Weight : 272.3
stdClass Object ( [pname] => (R,S)-Ambrisentan acyl-β-D-glucuronide [catalogue_number] => PA 28 0461002 [category_ids] => ,70,75,76,78,82,95, [chemical_name] => [weight] => 554.55 [form] => C28H30N2O10 [cas] => 1106685-82-8 [pslug] => 1106685-82-8-r-s-ambrisentan-acyl-beta-d-glucuronide-pa280461002 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0461002
Molecular Formula : C28H30N2O10
stdClass Object ( [pname] => Ambrisentan Hydroxy Acid Impurity (R-Isomer) [catalogue_number] => PA 28 0461003 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 272.3 [form] => C16H16O4 [cas] => 178306-49-5 [pslug] => 178306-49-5-ambrisentan-hydroxy-acid-impurity-r-isomer-pa280461003 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0461003
stdClass Object ( [pname] => rac 4-Hydroxymethyl Ambrisentan [catalogue_number] => PA 28 0461004 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 394.43 [form] => C22H22N2O5 [cas] => 1106685-84-0 [pslug] => 1106685-84-0-rac-4-hydroxymethyl-ambrisentan-pa280461004 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0461004
Molecular Formula : C22H22N2O5
Molecular Weight : 394.43
stdClass Object ( [pname] => Ethyl (S)-2-((4,6-dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoate [catalogue_number] => PA 28 0461005 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 406.48 [form] => C24H26N2O4 [cas] => 1349854-31-4 [pslug] => 1349854-31-4-ethyl-s-2-4-6-dimethylpyrimidin-2-yl-oxy-3-methoxy-3-3-diphenylpropanoate-pa280461005 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0461005
Molecular Formula : C24H26N2O4
Molecular Weight : 406.48
stdClass Object ( [pname] => 2-[(4,6-Dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenyl propanoic acid ethyl ester [catalogue_number] => PA 28 0461006 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 406.48 [form] => C24H26N2O4 [cas] => NA [pslug] => 2-4-6-dimethylpyrimidin-2-yl-oxy-3-methoxy-3-3-diphenyl-propanoic-acid-ethyl-ester-pa280461006 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0461006
stdClass Object ( [pname] => 2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3,3-diphenylacrylic acid [catalogue_number] => PA 28 0461007 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 346.39 [form] => C21H18N2O3 [cas] => 1312092-82-2 [pslug] => 1312092-82-2-2-4-6-dimethylpyrimidin-2-yl-oxy-3-3-diphenylacrylic-acid-pa280461007 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0461007
Molecular Formula : C21H18N2O3
Molecular Weight : 346.39
stdClass Object ( [pname] => Ambrisentan N-Oxide [catalogue_number] => PA 28 0461008 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 394.43 [form] => C22H22N2O5 [cas] => NA [pslug] => ambrisentan-n-oxide-pa280461008 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0461008
stdClass Object ( [pname] => (S)-2-((4-(Hydroxymethyl)-6-(methyl-d3)pyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid [catalogue_number] => PA STI 088903 [category_ids] => ,98,75,76,78,70,82, [chemical_name] => [weight] => 397.45 [form] => C22H19D3N2O5 [cas] => NA [pslug] => s-2-4-hydroxymethyl-6-methyl-d3-pyrimidin-2-yl-oxy-3-methoxy-3-3-diphenylpropanoic-acid-pasti088903 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 088903
Molecular Weight : 397.45
stdClass Object ( [pname] => Ambrisentan D3 [catalogue_number] => PA STI 088904 [category_ids] => ,98,75,76,78,70,82, [chemical_name] => [weight] => 381.45 [form] => C22H19D3N2O4 [cas] => 1046116-26-0 [pslug] => 1046116-26-0-ambrisentan-d3-pasti088904 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 088904
Molecular Weight : 381.45
stdClass Object ( [pname] => 2-((4,6-Dimethylpyrimidin-2-yl)oxy)-1-phenylethan-1-one [catalogue_number] => PAI 01 016041 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 242.28 [form] => C14H14N2O2 [cas] => 2052996-29-7 [pslug] => 2052996-29-7-2-4-6-dimethylpyrimidin-2-yl-oxy-1-phenylethan-1-one-pai01016041 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PAI 01 016041
Molecular Formula : C14H14N2O2
Molecular Weight : 242.28
stdClass Object ( [pname] => 2-((4,6-Dimethylpyrimidin-2-yl)oxy)-1,1-diphenylethan-1-ol [catalogue_number] => PAI 01 016042 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 320.39 [form] => C20H20N2O2 [cas] => 2052996-28-6 [pslug] => 2052996-28-6-2-4-6-dimethylpyrimidin-2-yl-oxy-1-1-diphenylethan-1-ol-pai01016042 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PAI 01 016042
Molecular Formula : C20H20N2O2
Molecular Weight : 320.39
stdClass Object ( [pname] => Diphenylacetaldehyde [catalogue_number] => PA 28 0461009 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 196.25 [form] => C14H12O [cas] => 947-91-1 [pslug] => 947-91-1-diphenylacetaldehyde-pa280461009 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0461009
Molecular Formula : C14H12O
Molecular Weight : 196.25
stdClass Object ( [pname] => 4-Hydroxymethyl Ambrisentan D5 [catalogue_number] => PA STI 089231 [category_ids] => ,98,75,76,78,70,82, [chemical_name] => [weight] => 399.46 [form] => C22H17D5N2O5 [cas] => 2012598-50-2 [pslug] => 2012598-50-2-4-hydroxymethyl-ambrisentan-d5-pasti089231 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 089231
Molecular Formula : C22H17D5N2O5
Molecular Weight : 399.46
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