leflunomide
Enzyme inhibitors
- An immunomodulatory drug, Leflunomide is used to treat rheumatoid arthritis and psoriatic arthritis. An inhibitor of enzyme dihydroorotate dehydrogenase which plays a key role in the synthesis of uridine monophosphate (rUMP), which is required for the synthesis of DNA and RNA. Reference standards of Leflunomide API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
(
[pname] => Leflunomide
[catalogue_number] => PA 12 08000
[category_ids] => ,82,81,80,78,71,70,
[chemical_name] =>
[weight] => 270.21
[form] => C12H9F3N2O2
[cas] => 75706-12-6
[pslug] => 75706-12-6-leflunomide-api-pa1208000
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Catalogue No.:PA 12 08000
Molecular Formula : C12H9F3N2O2
Molecular Weight : 270.21
stdClass Object
(
[pname] => Leflunomide-d4
[catalogue_number] => PA STI 056310
[category_ids] => ,80,71,98,78,70,82,81,
[chemical_name] =>
[weight] => 274.23
[form] => C12H5D4F3N2O2
[cas] => 1189987-23-2
[pslug] => 1189987-23-2-leflunomide-d4-pasti056310
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Catalogue No.:PA STI 056310
Molecular Formula : C12H5D4F3N2O2
Molecular Weight : 274.23
stdClass Object
(
[pname] => N-(Chloromethyl)-4-(trifluoromethyl)aniline
[catalogue_number] => PA 12 0081002
[category_ids] => ,82,81,80,78,71,70,
[chemical_name] =>
[weight] => 209.6
[form] => C8H7ClF3N
[cas] => 1903709-86-3
[pslug] => 1903709-86-3-n-chloromethyl-4-trifluoromethyl-aniline-pa120081002
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N-(Chloromethyl)-4-(trifluoromethyl)aniline
