Dolutegravir-impurities | Pharmaffiliates

dolutegravir

Dolutegravir is a HIV-1 intergrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell.. Reference standards of Dolutegravir API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

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    [pname] => Dolutegravir Sodium Salt - API Standards
    [catalogue_number] => PA 04 95600
    [category_ids] => ,89,82,81,78,71,70,
    [chemical_name] => 
    [weight] => 441.36
    [form] => C20H18F2N3NaO5
    [cas] => 1051375-19-9
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PA 04 95600

Dolutegravir Sodium Salt - API Standards


  • Catalogue No.:PA 04 95600

  • CAS :

    1051375-19-9

  • Molecular Formula : C20H18F2N3NaO5

  • Molecular Weight : 441.36

stdClass Object
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    [pname] => Dolutegravir - API Standards 
    [catalogue_number] => PA 04 95000
    [category_ids] => ,77,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 419.38
    [form] => C20H19F2N3O5
    [cas] => 1051375-16-6
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PA 04 95000

Dolutegravir - API Standards


  • Catalogue No.:PA 04 95000

  • CAS :

    1051375-16-6

  • Molecular Formula : C20H19F2N3O5

  • Molecular Weight : 419.38

stdClass Object
(
    [pname] => 4-Fluoro Dolutegravir
    [catalogue_number] => PA 04 95510
    [category_ids] => ,70,71,77,78,80,81,82,
    [chemical_name] => 
    [weight] => 401.39
    [form] => C20H20FN3O5
    [cas] => 1863916-88-4
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PA 04 95510

4-Fluoro Dolutegravir


  • Catalogue No.:PA 04 95510

  • CAS :

    1863916-88-4

  • Molecular Formula : C20H20FN3O5

  • Molecular Weight : 401.39

stdClass Object
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    [pname] => (4S,12aS)-7-Methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid
    [catalogue_number] => PA 04 95550
    [category_ids] => ,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 308.29
    [form] => C14H16N2O6
    [cas] => 2730133-58-9
    [pslug] => 2730133-58-9-4s-12as-7-methoxy-4-methyl-6-8-dioxo-3-4-6-8-12-12a-hexahydro-2h-pyrido-1-2-4-5-pyrazino-2-1-b-1-3-oxazine-9-carboxylic-acid-pa0495550
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PA 04 95550

(4S,12aS)-7-Methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid


  • Catalogue No.:PA 04 95550

  • CAS :

    2730133-58-9

  • Molecular Formula : C14H16N2O6

  • Molecular Weight : 308.29

stdClass Object
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    [pname] => (R)-7-(2,4-Difluorobenzylcarbamoyl)-2-(4-(2,4-difluorobenzylcarbamoyloxy)butan-2-yl)-1,8-dioxo-2,8-dihydro-1H-pyrido[1,2-a]pyrazine-9-olate Sodium Salt
    [catalogue_number] => PA 04 95590
    [category_ids] => ,71,81,78,70,82,89,
    [chemical_name] => 
    [weight] => 610.49
    [form] => C28H23F4N4NaO6
    [cas] => NA
    [pslug] => r-7-2-4-difluorobenzylcarbamoyl-2-4-2-4-difluorobenzylcarbamoyloxy-butan-2-yl-1-8-dioxo-2-8-dihydro-1h-pyrido-1-2-a-pyrazine-9-olate-sodium-salt-pa0495590
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PA 04 95590

(R)-7-(2,4-Difluorobenzylcarbamoyl)-2-(4-(2,4-difluorobenzylcarbamoyloxy)butan-2-yl)-1,8-dioxo-2,8-dihydro-1H-pyrido[1,2-a]pyrazine-9-olate Sodium Salt


  • Catalogue No.:PA 04 95590

  • CAS :

    NA

  • Molecular Formula : C28H23F4N4NaO6

  • Molecular Weight : 610.49

stdClass Object
(
    [pname] => Dolutegravir O-beta-D-Glucuronide
    [catalogue_number] => PA 04 0951035
    [category_ids] => ,70,71,77,78,80,81,82,95,
    [chemical_name] => 
    [weight] => 595.51
    [form] => C26H27F2N3O11
    [cas] => 1485692-21-4
    [pslug] => 1485692-21-4-dolutegravir-o-beta-d-glucuronide-pa040951035
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PA 04 0951035

Dolutegravir O-beta-D-Glucuronide


  • Catalogue No.:PA 04 0951035

  • CAS :

    1485692-21-4

  • Molecular Formula : C26H27F2N3O11

  • Molecular Weight : 595.51

stdClass Object
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    [pname] => Ethyl (4R,12aS)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylate
    [catalogue_number] => PA 04 0951040
    [category_ids] => ,77,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 322.32
    [form] => C15H18N2O6
    [cas] => 2677842-37-2
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PA 04 0951040

Ethyl (4R,12aS)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylate


  • Catalogue No.:PA 04 0951040

  • CAS :

    2677842-37-2

  • Molecular Formula : C15H18N2O6

  • Molecular Weight : 322.32

stdClass Object
(
    [pname] => (R)-9-Hydroxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxylic Acid
    [catalogue_number] => PA 04 0951041
    [category_ids] => ,77,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 294.26
    [form] => C13H14N2O6
    [cas] => NA
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PA 04 0951041

(R)-9-Hydroxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxylic Acid


  • Catalogue No.:PA 04 0951041

  • CAS :

    NA

  • Molecular Formula : C13H14N2O6

  • Molecular Weight : 294.26

stdClass Object
(
    [pname] => 1,3-Bis(2,4-difluorobenzyl)urea
    [catalogue_number] => PA 04 0951042
    [category_ids] => ,77,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 312.27
    [form] => C15H12F4N2O
    [cas] => NA
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PA 04 0951042

1,3-Bis(2,4-difluorobenzyl)urea


  • Catalogue No.:PA 04 0951042

  • CAS :

    NA

  • Molecular Formula : C15H12F4N2O

  • Molecular Weight : 312.27

stdClass Object
(
    [pname] => (4R,12aS)-N-(4-((2,4-Difluorobenzyl)amino)-2-fluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
    [catalogue_number] => PA 04 0951047
    [category_ids] => ,77,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 556.54
    [form] => C28H27F3N4O5
    [cas] => 2767197-74-8
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PA 04 0951047

(4R,12aS)-N-(4-((2,4-Difluorobenzyl)amino)-2-fluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide


  • Catalogue No.:PA 04 0951047

  • CAS :

    2767197-74-8

  • Molecular Formula : C28H27F3N4O5

  • Molecular Weight : 556.54

stdClass Object
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    [pname] => 5-((2,4-Difluorobenzyl)carbamoyl)-3-hydroxy-1-((4-methyl-1,3-oxazinan-2-yl)methyl)-4-oxo-1,4-dihydropyridine-2-carboxylic Acid
    [catalogue_number] => PA 04 0951048
    [category_ids] => ,77,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 437.4
    [form] => C20H21F2N3O6
    [cas] => 1800247-07-7
    [pslug] => 1800247-07-7-5-2-4-difluorobenzyl-carbamoyl-3-hydroxy-1-4-methyl-1-3-oxazinan-2-yl-methyl-4-oxo-1-4-dihydropyridine-2-carboxylic-acid-pa040951048
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PA 04 0951048

5-((2,4-Difluorobenzyl)carbamoyl)-3-hydroxy-1-((4-methyl-1,3-oxazinan-2-yl)methyl)-4-oxo-1,4-dihydropyridine-2-carboxylic Acid


  • Catalogue No.:PA 04 0951048

  • CAS :

    1800247-07-7

  • Molecular Formula : C20H21F2N3O6

  • Molecular Weight : 437.4