pyrimethamine
Used for the treatment of toxoplasmosis ( a parasitic disease) and cystoisosporiasis (human intestinal parasitic disease ) in combination with leucovorin. It works by inhibiting the synthesis of RNA and DNA in many species. A dihydrofolate reductase inhibitor.Reference standards of Pyrimethamine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
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[pname] => Pyrimethamine
[catalogue_number] => PA 43 01000
[category_ids] => ,70,71,78,79,82,83,85,
[chemical_name] =>
[weight] => 248.71
[form] => C12H13ClN4
[cas] => 58-14-0
[pslug] => 58-14-0-pyrimethamine-api-pa4301000
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Catalogue No.:PA 43 01000
Molecular Formula : C12H13ClN4
Molecular Weight : 248.71
stdClass Object
(
[pname] => 2-(4-Chlorophenyl)-2-(2-ethyl-1,3-dioxolan-2-yl)acetonitrile
[catalogue_number] => PA 43 01510
[category_ids] => ,79,71,85,83,78,70,82,
[chemical_name] =>
[weight] => 251.71
[form] => C13H14ClNO2
[cas] => 55474-41-4
[pslug] => 55474-41-4-2-4-chlorophenyl-2-2-ethyl-1-3-dioxolan-2-yl-acetonitrile-pa4301510
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2-(4-Chlorophenyl)-2-(2-ethyl-1,3-dioxolan-2-yl)acetonitrile
Catalogue No.:PA 43 01510
Molecular Formula : C13H14ClNO2
Molecular Weight : 251.71
stdClass Object
(
[pname] => Pyrimethamine E-isomer
[catalogue_number] => PA 43 01520
[category_ids] => ,79,71,85,83,78,70,82,
[chemical_name] =>
[weight] => 207.66
[form] => C11H10ClNO
[cas] => 118364-47-9
[pslug] => 118364-47-9-pyrimethamine-e-isomer-pa4301520
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Catalogue No.:PA 43 01520
Molecular Formula : C11H10ClNO
Molecular Weight : 207.66
stdClass Object
(
[pname] => Pyrimethamine Z-isomer
[catalogue_number] => PA 43 01530
[category_ids] => ,79,71,85,83,78,70,82,
[chemical_name] =>
[weight] => 207.66
[form] => C11H10ClNO
[cas] => 118364-40-2
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Catalogue No.:PA 43 01530
Molecular Formula : C11H10ClNO
Molecular Weight : 207.66
stdClass Object
(
[pname] => Pyrimethamine E/Z-Mixture
[catalogue_number] => PA 43 01540
[category_ids] => ,79,71,85,83,78,70,82,
[chemical_name] =>
[weight] => 207.66
[form] => C11H10ClNO
[cas] => 855377-91-2
[pslug] => 855377-91-2-pyrimethamine-e-z-mixture-pa4301540
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Pyrimethamine E/Z-Mixture
Catalogue No.:PA 43 01540
Molecular Formula : C11H10ClNO
Molecular Weight : 207.66
