tofacitinib citrate
A janus kinase (JAK) inhibitor class of drug used for the treatment of rheumatoid arthritis (RA)Reference standards of Tofacitinib Citrate API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[form] => C16H20N6O
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Catalogue No.:PA 47 13510
Molecular Formula : C16H20N6O
Molecular Weight : 312.37
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[catalogue_number] => PA 47 13520
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[form] => C16H20N6O
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Catalogue No.:PA 47 13520
Molecular Formula : C16H20N6O
Molecular Weight : 312.37
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N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Catalogue No.:PA 47 13540
Molecular Formula : C13H19N5
Molecular Weight : 245.32
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[weight] => 262.31
[form] => C13H18N4O2
[cas] => NA
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2-Cyano-N-((3R,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl)-N-methylacetamide
Catalogue No.:PA 47 13560
Molecular Formula : C13H18N4O2
Molecular Weight : 262.31
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[weight] => 218.34
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N,4-Dimethyl-1-benzyl-3-piperidinamine
Catalogue No.:PA 47 13570
Molecular Formula : C14H22N2
Molecular Weight : 218.34
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[weight] => 291.26
[form] => C14H24Cl2N2
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(3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride
Catalogue No.:PA 47 13590
Molecular Formula : C14H24Cl2N2
Molecular Weight : 291.26
stdClass Object
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[weight] => 331.37
[form] => C16H21N5O3
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3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoic Acid
Catalogue No.:PA 47 13600
Molecular Formula : C16H21N5O3
Molecular Weight : 331.37
stdClass Object
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[form] => C16H22N6O2
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3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanamide
Catalogue No.:PA 47 13610
Molecular Formula : C16H22N6O2
Molecular Weight : 330.38
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N-Methyl-N-((3S,4S)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Catalogue No.:PA 47 13630
Molecular Formula : C13H19N5
Molecular Weight : 245.32
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Des-(N-oxopropanenitrile)-N-methylbenzyl
Catalogue No.:PA 47 13640
Molecular Formula : C20H25N5
Molecular Weight : 335.45
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N-((3S,4S)-1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Catalogue No.:PA 47 13650
Molecular Formula : C20H25N5
Molecular Weight : 335.45
stdClass Object
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[form] => C16H20N6O
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3-(4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Catalogue No.:PA 47 13660
Molecular Formula : C16H20N6O
Molecular Weight : 312.37
stdClass Object
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[catalogue_number] => PA 47 13680
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[weight] => 307.76
[form] => C13H10ClN3O2S
[cas] => 479633-63-1
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4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine
Catalogue No.:PA 47 13680
Molecular Formula : C13H10ClN3O2S
Molecular Weight : 307.76
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[chemical_name] =>
[weight] => 349.47
[form] => C21H27N5
[cas] => 2641343-91-9
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N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N,7-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Catalogue No.:PA 47 13690
Molecular Formula : C21H27N5
Molecular Weight : 349.47
stdClass Object
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[pname] => Tofacitinib N-Oxide
[catalogue_number] => PA 47 13700
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[chemical_name] =>
[weight] => 328.38
[form] => C16H20N6O2
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Catalogue No.:PA 47 13700
Molecular Formula : C16H20N6O2
Molecular Weight : 328.38
stdClass Object
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[weight] => 287.37
[form] => C15H21N5O
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1-((3R,4R)-4-Methyl-3-(methyl(1H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)ethan-1-one
Catalogue No.:PA 47 13710
Molecular Formula : C15H21N5O
Molecular Weight : 287.37
stdClass Object
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[weight] => 259.36
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N-((3R,4R)-1,4-Dimethylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Catalogue No.:PA 47 13720
Molecular Formula : C14H21N5
Molecular Weight : 259.36
stdClass Object
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[weight] => 245.33
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N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Catalogue No.:PA 47 13730
Molecular Formula : C13H19N5
Molecular Weight : 245.33
stdClass Object
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[form] => C22H30N6O8
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3-((3R,4R)-3-((6,7-Dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile 2-hydroxypropane-1,2,3-tricarboxylate
Catalogue No.:PA 47 13740
Molecular Formula : C22H30N6O8
Molecular Weight : 506.52
stdClass Object
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[weight] => 504.5
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3-(4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile 2-hydroxypropane-1,2,3-tricarboxylate
stdClass Object
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[catalogue_number] => PA 47 13760
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[weight] => 504.5
[form] => C22H28N6O8
[cas] => 2174011-55-1
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3-((3S,4S)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile 2-Hydroxypropane-1,2,3-tricarboxylate
stdClass Object
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[catalogue_number] => PA 47 13780
[category_ids] => ,79,80,78,70,82,
[chemical_name] =>
[weight] => 346.39
[form] => C16H22N6O3
[cas] => 2101951-13-5
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3-((3R,4R)-3-(((5S,6R)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile
Catalogue No.:PA 47 13780
Molecular Formula : C16H22N6O3
Molecular Weight : 346.39
stdClass Object
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[catalogue_number] => PA 47 13800
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[weight] => 362.39
[form] => C16H22N6O4
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3-((3R,4R)-4-Methyl-3-(methyl((5R,6S)-2,5,6-trihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Catalogue No.:PA 47 13800
Molecular Formula : C16H22N6O4
Molecular Weight : 362.39
stdClass Object
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[catalogue_number] => PA 47 13810
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[weight] => 362.39
[form] => C16H22N6O4
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3-((3R,4R)-4-Methyl-3-(methyl((5S,6R)-2,5,6-trihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Catalogue No.:PA 47 13810
Molecular Formula : C16H22N6O4
Molecular Weight : 362.39
stdClass Object
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[pname] => 3-Imino-5-((3S,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)-2-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carbonyl)-5-oxopentanenitrile
[catalogue_number] => PA 47 13840
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[weight] => 623.77
[form] => C33H41N11O2
[cas] => NA
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3-Imino-5-((3S,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)-2-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carbonyl)-5-oxopentanenitrile
Catalogue No.:PA 47 13840
Molecular Formula : C33H41N11O2
Molecular Weight : 623.77
stdClass Object
(
[pname] => 3-((3R,4R)-3-((2-Chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile
[catalogue_number] => PA 47 13850
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[chemical_name] =>
[weight] => 346.82
[form] => C16H19ClN6O
[cas] => 1616761-00-2
[pslug] => 1616761-00-2-3-3r-4r-3-2-chloro-7h-pyrrolo-2-3-d-pyrimidin-4-yl-methyl-amino-4-methylpiperidin-1-yl-3-oxopropanenitrile-pa4713850
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3-((3R,4R)-3-((2-Chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile
Catalogue No.:PA 47 13850
Molecular Formula : C16H19ClN6O
Molecular Weight : 346.82
stdClass Object
(
[pname] => (3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine 1-Oxide
[catalogue_number] => PA 47 13860
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[weight] => 261.33
[form] => C13H19N5O
[cas] => NA
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(3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine 1-Oxide
Catalogue No.:PA 47 13860
Molecular Formula : C13H19N5O
Molecular Weight : 261.33
stdClass Object
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[pname] => 4-Cyano-2-hydroxy-5-(4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopentane-1,2,3-tricarboxylic Acid
[catalogue_number] => PA 47 0131007
[category_ids] => ,82,80,79,78,70,
[chemical_name] =>
[weight] => 502.48
[form] => C22H26N6O8
[cas] => NA
[pslug] => 4-cyano-2-hydroxy-5-4-methyl-3-methyl-7h-pyrrolo-2-3-d-pyrimidin-4-yl-amino-piperidin-1-yl-5-oxopentane-1-2-3-tricarboxylic-acid-pa470131007
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4-Cyano-2-hydroxy-5-(4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopentane-1,2,3-tricarboxylic Acid
Catalogue No.:PA 47 0131007
Molecular Formula : C22H26N6O8
Molecular Weight : 502.48
stdClass Object
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[pname] => (3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine
[catalogue_number] => PA 47 0131008
[category_ids] => ,82,78,75,71,70,80,
[chemical_name] =>
[weight] => 218.34
[form] => C14H22N2
[cas] => 1638499-33-8
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(3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine
Catalogue No.:PA 47 0131008
Molecular Formula : C14H22N2
Molecular Weight : 218.34
