pyrimethamine
Used for the treatment of toxoplasmosis ( a parasitic disease) and cystoisosporiasis (human intestinal parasitic disease ) in combination with leucovorin. It works by inhibiting the synthesis of RNA and DNA in many species. A dihydrofolate reductase inhibitor.Reference standards of Pyrimethamine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
(
[pname] => α-(4-Chlorophenyl)-α-propionylacetonitrile
[catalogue_number] => PA 43 01550
[category_ids] => ,80,70,
[chemical_name] =>
[weight] => 207.66
[form] => C11H10ClNO
[cas] => 55474-40-3
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α-(4-Chlorophenyl)-α-propionylacetonitrile
Catalogue No.:PA 43 01550
Molecular Formula : C11H10ClNO
Molecular Weight : 207.66
stdClass Object
(
[pname] => Pyrimethamine - Impurity D
[catalogue_number] => PA 43 01560
[category_ids] => ,70,78,80,82,
[chemical_name] =>
[weight] => 251.71
[form] => C13H14ClNO2
[cas] => NA
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Pyrimethamine - Impurity D
Catalogue No.:PA 43 01560
Molecular Formula : C13H14ClNO2
Molecular Weight : 251.71
stdClass Object
(
[pname] => Pyrimethamine - Impurity B
[catalogue_number] => PA 20 57530
[category_ids] => 82,80,79,78,70
[chemical_name] =>
[weight] => 234.68
[form] => C11H11ClN4
[cas] => 3275-44-3
[pslug] => 3275-44-3-pyrimethamine-impurity-b-pa2057530
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Pyrimethamine - Impurity B
Catalogue No.:PA 20 57530
Molecular Formula : C11H11ClN4
Molecular Weight : 234.68
stdClass Object
(
[pname] => Ethyl 2-(4-chlorophenyl)-3-oxopentanoate
[catalogue_number] => PA 43 01570
[category_ids] => ,92,80,78,70,82,
[chemical_name] =>
[weight] => 254.71
[form] => C13H15ClO3
[cas] => 100713-76-6
[pslug] => 100713-76-6-ethyl-2-4-chlorophenyl-3-oxopentanoate-pa4301570
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Ethyl 2-(4-chlorophenyl)-3-oxopentanoate
Catalogue No.:PA 43 01570
Molecular Formula : C13H15ClO3
Molecular Weight : 254.71
stdClass Object
(
[pname] => (Z)-2-(4-Chlorophenyl)-3-hydroxypent-2-enenitrile
[catalogue_number] => PA 43 01580
[category_ids] => ,92,80,78,70,82,
[chemical_name] =>
[weight] => 207.66
[form] => C11H10ClNO
[cas] => 945042-30-8
[pslug] => 945042-30-8-z-2-4-chlorophenyl-3-hydroxypent-2-enenitrile-pa4301580
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(Z)-2-(4-Chlorophenyl)-3-hydroxypent-2-enenitrile
Catalogue No.:PA 43 01580
Molecular Formula : C11H10ClNO
Molecular Weight : 207.66