leflunomide
Aromatics
- An immunomodulatory drug, Leflunomide is used to treat rheumatoid arthritis and psoriatic arthritis. An inhibitor of enzyme dihydroorotate dehydrogenase which plays a key role in the synthesis of uridine monophosphate (rUMP), which is required for the synthesis of DNA and RNA. Reference standards of Leflunomide API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Leflunomide
[catalogue_number] => PA 12 08000
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[weight] => 270.21
[form] => C12H9F3N2O2
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Catalogue No.:PA 12 08000
Molecular Formula : C12H9F3N2O2
Molecular Weight : 270.21
stdClass Object
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[pname] => Leflunomide - Impurity A
[catalogue_number] => PA 12 08010
[category_ids] => ,104,79,80,
[chemical_name] =>
[weight] => 161.12
[form] => C7H6F3N
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Catalogue No.:PA 12 08010
Molecular Formula : C7H6F3N
Molecular Weight : 161.12
stdClass Object
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[pname] => Leflunomide - Impurity C
[catalogue_number] => PA 12 08030
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[form] => C12H9F3N2O2
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Catalogue No.:PA 12 08030
Molecular Formula : C12H9F3N2O2
Molecular Weight : 270.21
stdClass Object
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[pname] => Leflunomide - Impurity E
[catalogue_number] => PA 12 08050
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[weight] => 270.21
[form] => C12H9F3N2O2
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Catalogue No.:PA 12 08050
Molecular Formula : C12H9F3N2O2
Molecular Weight : 270.21
stdClass Object
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[pname] => Leflunomide - Impurity F
[catalogue_number] => PA 12 08060
[category_ids] => ,70,71,75,78,80,82,
[chemical_name] =>
[weight] => 270.21
[form] => C12H9F3N2O2
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Catalogue No.:PA 12 08060
Molecular Formula : C12H9F3N2O2
Molecular Weight : 270.21
stdClass Object
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[pname] => Leflunomide - Impurity G
[catalogue_number] => PA 12 08070
[category_ids] => ,80,71,75,78,70,82,
[chemical_name] =>
[weight] => 216.24
[form] => C12 H12 N2 O2
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Catalogue No.:PA 12 08070
Molecular Formula : C12 H12 N2 O2
Molecular Weight : 216.24
stdClass Object
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[pname] => Leflunomide - Impurity H
[catalogue_number] => PA 12 08080
[category_ids] => ,80,79,
[chemical_name] =>
[weight] => 228.17
[form] => C10H7F3N2O
[cas] => 24522-30-3
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Catalogue No.:PA 12 08080
Molecular Formula : C10H7F3N2O
Molecular Weight : 228.17
stdClass Object
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[pname] => 5-Hydroxy Leflunomide-d4 (Metabolite M2)
[catalogue_number] => PA STI 049540
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[chemical_name] =>
[weight] => 290.23
[form] => C12H5D4F3N2O3
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5-Hydroxy Leflunomide-d4 (Metabolite M2)
Catalogue No.:PA STI 049540
Molecular Formula : C12H5D4F3N2O3
Molecular Weight : 290.23
stdClass Object
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[pname] => Leflunomide-d4
[catalogue_number] => PA STI 056310
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[weight] => 274.23
[form] => C12H5D4F3N2O2
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Catalogue No.:PA STI 056310
Molecular Formula : C12H5D4F3N2O2
Molecular Weight : 274.23
stdClass Object
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[pname] => N-(Chloromethyl)-4-(trifluoromethyl)aniline
[catalogue_number] => PA 12 0081002
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[weight] => 209.6
[form] => C8H7ClF3N
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N-(Chloromethyl)-4-(trifluoromethyl)aniline
