Dabrafenib-impurities | Pharmaffiliates

dabrafenib

Dabrafenib is a reversible ATP-competitive kinase inhibitor and targets the MAPK pathway. It is used alone or in combination with another medication to treat a type of skin cancer.. Reference standards of Dabrafenib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

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    [pname] => Dabrafenib - API Standards 
    [catalogue_number] => PA 31 06000
    [category_ids] => ,79,80,71,78,70,82,89,88,
    [chemical_name] => 
    [weight] => 519.56
    [form] => C23H20F3N5O2S2
    [cas] => 1195765-45-7
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PA 31 06000

Dabrafenib - API Standards


  • Catalogue No.:PA 31 06000

  • CAS :

    1195765-45-7

  • Molecular Formula : C23H20F3N5O2S2

  • Molecular Weight : 519.56

stdClass Object
(
    [pname] => 3-Bromo-2-fluorobenzoic Acid
    [catalogue_number] => PA 31 06510
    [category_ids] => ,80,89,
    [chemical_name] => 
    [weight] => 219.01
    [form] => C7H4BrFO2
    [cas] => 161957-56-8
    [pslug] => 161957-56-8-3-bromo-2-fluorobenzoic-acid-pa3106510
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PA 31 06510

3-Bromo-2-fluorobenzoic Acid


  • Catalogue No.:PA 31 06510

  • CAS :

    161957-56-8

  • Molecular Formula : C7H4BrFO2

  • Molecular Weight : 219.01

stdClass Object
(
    [pname] => Dabrafenib Mesylate
    [catalogue_number] => PA 31 06520
    [category_ids] => ,80,89,88,79,
    [chemical_name] => 
    [weight] => 615.67
    [form] => C24H24F3N5O5S3
    [cas] => 1195768-06-9
    [pslug] => 1195768-06-9-dabrafenib-mesylate-pa3106520
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PA 31 06520

Dabrafenib Mesylate


  • Catalogue No.:PA 31 06520

  • CAS :

    1195768-06-9

  • Molecular Formula : C24H24F3N5O5S3

  • Molecular Weight : 615.67

stdClass Object
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    [pname] => 2,6-Difluorobenzenesulfonyl Chloride
    [catalogue_number] => PA 31 06530
    [category_ids] => ,80,88,
    [chemical_name] => 
    [weight] => 212.6
    [form] => C6H3ClF2O2S
    [cas] => 60230-36-6
    [pslug] => 60230-36-6-2-6-difluorobenzenesulfonyl-chloride-pa3106530
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PA 31 06530

2,6-Difluorobenzenesulfonyl Chloride


  • Catalogue No.:PA 31 06530

  • CAS :

    60230-36-6

  • Molecular Formula : C6H3ClF2O2S

  • Molecular Weight : 212.6

stdClass Object
(
    [pname] => M30-Dabrafenib
    [catalogue_number] => PA 31 0061017
    [category_ids] => ,79,80,71,78,70,82,89,88,
    [chemical_name] => 
    [weight] => 551.52
    [form] => C22H16F3N5O5S2
    [cas] => 1613724-38-1
    [pslug] => 1613724-38-1-m30-dabrafenib-pa310061017
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PA 31 0061017

M30-Dabrafenib


  • Catalogue No.:PA 31 0061017

  • CAS :

    1613724-38-1

  • Molecular Formula : C22H16F3N5O5S2

  • Molecular Weight : 551.52

stdClass Object
(
    [pname] => M31-Dabrafenib
    [catalogue_number] => PA 31 0061018
    [category_ids] => ,79,80,71,78,70,82,89,88,
    [chemical_name] => 
    [weight] => 503.52
    [form] => C22H16F3N5O2S2
    [cas] => 1613724-51-8
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PA 31 0061018

M31-Dabrafenib


  • Catalogue No.:PA 31 0061018

  • CAS :

    1613724-51-8

  • Molecular Formula : C22H16F3N5O2S2

  • Molecular Weight : 503.52

stdClass Object
(
    [pname] => Dabrafenib Glucuronide
    [catalogue_number] => PA 31 0061019
    [category_ids] => ,79,80,71,78,70,82,89,88,95,
    [chemical_name] => 
    [weight] => 695.64
    [form] => C28H24F3N5O9S2
    [cas] => 2147682-66-2
    [pslug] => 2147682-66-2-dabrafenib-glucuronide-pa310061019
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PA 31 0061019

Dabrafenib Glucuronide


  • Catalogue No.:PA 31 0061019

  • CAS :

    2147682-66-2

  • Molecular Formula : C28H24F3N5O9S2

  • Molecular Weight : 695.64

stdClass Object
(
    [pname] => 1-(2-chloropyrimidin-4-yl)-2-(3-((2,6-difluorophenyl)sulfonamido)-2-fluorophenyl)-2-oxoethyl 2,2-dimethylpropanimidothioate
    [catalogue_number] => PA 31 0061020
    [category_ids] => ,70,75,78,80,82,
    [chemical_name] => 
    [weight] => 557
    [form] => C23H20ClF3N4O3S2
    [cas] => NA
    [pslug] => 1-2-chloropyrimidin-4-yl-2-3-2-6-difluorophenyl-sulfonamido-2-fluorophenyl-2-oxoethyl-2-2-dimethylpropanimidothioate-pa310061020
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PA 31 0061020

1-(2-chloropyrimidin-4-yl)-2-(3-((2,6-difluorophenyl)sulfonamido)-2-fluorophenyl)-2-oxoethyl 2,2-dimethylpropanimidothioate


  • Catalogue No.:PA 31 0061020

  • CAS :

    NA

  • Molecular Formula : C23H20ClF3N4O3S2

  • Molecular Weight : 557

stdClass Object
(
    [pname] => N-(3-(2-(Tert-butyl)-5-(2-chloropyrimidin-4-yl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide
    [catalogue_number] => PA 31 0061026
    [category_ids] => 89,88,80,79,71,82,78,70
    [chemical_name] => 
    [weight] => 538.99
    [form] => C23H18ClF3N4O2S2
    [cas] => 1195768-23-0
    [pslug] => 1195768-23-0-n-3-2-tert-butyl-5-2-chloropyrimidin-4-yl-thiazol-4-yl-2-fluorophenyl-2-6-difluorobenzenesulfonamide-pa310061026
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PA 31 0061026

N-(3-(2-(Tert-butyl)-5-(2-chloropyrimidin-4-yl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide


  • Catalogue No.:PA 31 0061026

  • CAS :

    1195768-23-0

  • Molecular Formula : C23H18ClF3N4O2S2

  • Molecular Weight : 538.99

stdClass Object
(
    [pname] => Dabrafenib Amine Impurity
    [catalogue_number] => PA 31 0061028
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 343.42
    [form] => C17H18FN5S
    [cas] => 1195769-01-7
    [pslug] => 1195769-01-7-dabrafenib-amine-impurity-pa310061028
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PA 31 0061028

Dabrafenib Amine Impurity


  • Catalogue No.:PA 31 0061028

  • CAS :

    1195769-01-7

  • Molecular Formula : C17H18FN5S

  • Molecular Weight : 343.42

stdClass Object
(
    [pname] => N-(3-(2-(2-Aminopyrimidin-4-yl)acetyl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide
    [catalogue_number] => PA 31 0061029
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 422.38
    [form] => C18H13F3N4O3S
    [cas] => NA
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PA 31 0061029

N-(3-(2-(2-Aminopyrimidin-4-yl)acetyl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide


  • Catalogue No.:PA 31 0061029

  • CAS :

    NA

  • Molecular Formula : C18H13F3N4O3S

  • Molecular Weight : 422.38