avanafil
Chemically, it is a derivative of pyrimidine and is only available as the S-enantiomer. Avanafil is a new phosphodiesterase-5 inhibitor that is faster acting and more selective than other drugs belonging to the same class. . Reference standards of Avanafil API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
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[pname] => Avanafil
[catalogue_number] => PA 28 44000
[category_ids] => ,80,69,71,78,70,82,92,
[chemical_name] =>
[weight] => 483.95
[form] => C23H26ClN7O3
[cas] => 330784-47-9
[pslug] => 330784-47-9-avanafil-api-pa2844000
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Catalogue No.:PA 28 44000
Molecular Formula : C23H26ClN7O3
Molecular Weight : 483.95
stdClass Object
(
[pname] => Avanafil Deschloro Impurity
[catalogue_number] => PA 28 44510
[category_ids] => 82,80,79,78,71,70
[chemical_name] =>
[weight] => 449.51
[form] => C23H27N7O3
[cas] => 330784-50-4
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Avanafil Deschloro Impurity
Catalogue No.:PA 28 44510
Molecular Formula : C23H27N7O3
Molecular Weight : 449.51
stdClass Object
(
[pname] => Avanafil Amide Analog
[catalogue_number] => PA 28 44520
[category_ids] => ,80,71,78,70,82,79,
[chemical_name] =>
[weight] => 391.85
[form] => C18H22ClN5O3
[cas] => 372117-54-9
[pslug] => 372117-54-9-avanafil-amide-analog-pa2844520
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Catalogue No.:PA 28 44520
Molecular Formula : C18H22ClN5O3
Molecular Weight : 391.85
stdClass Object
(
[pname] => Avanafil N-Methyl Analog
[catalogue_number] => PA 28 44530
[category_ids] => ,80,71,78,70,82,79,
[chemical_name] =>
[weight] => 405.88
[form] => C19H24ClN5O3
[cas] => 372117-53-8
[pslug] => 372117-53-8-avanafil-n-methyl-analog-pa2844530
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Catalogue No.:PA 28 44530
Molecular Formula : C19H24ClN5O3
Molecular Weight : 405.88
stdClass Object
(
[pname] => Avanafil N-ethyl Analog
[catalogue_number] => PA 28 44540
[category_ids] => ,80,71,78,70,82,79,
[chemical_name] =>
[weight] => 419.91
[form] => C20H26ClN5O3
[cas] => 2520114-39-8
[pslug] => 2520114-39-8-avanafil-n-ethyl-analog-pa2844540
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Catalogue No.:PA 28 44540
Molecular Formula : C20H26ClN5O3
Molecular Weight : 419.91
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(
[pname] => Avanafil O-Desmethyl Analog
[catalogue_number] => PA 28 44550
[category_ids] => ,80,71,78,70,82,79,
[chemical_name] =>
[weight] => 469.92
[form] => C22H24ClN7O3
[cas] => 330785-05-2
[pslug] => 330785-05-2-avanafil-o-desmethyl-analog-pa2844550
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Avanafil O-Desmethyl Analog
Catalogue No.:PA 28 44550
Molecular Formula : C22H24ClN7O3
Molecular Weight : 469.92
stdClass Object
(
[pname] => Avanafil Ethyl Ester Analog
[catalogue_number] => PA 28 44560
[category_ids] => ,80,71,78,70,82,79,
[chemical_name] =>
[weight] => 420.89
[form] => C20H25ClN4O4
[cas] => 1638497-22-9
[pslug] => 1638497-22-9-avanafil-ethyl-ester-analog-pa2844560
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Avanafil Ethyl Ester Analog
Catalogue No.:PA 28 44560
Molecular Formula : C20H25ClN4O4
Molecular Weight : 420.89
stdClass Object
(
[pname] => Avanafil Carboxylic Acid Analog
[catalogue_number] => PA 28 44570
[category_ids] => 82,80,79,78,71,70
[chemical_name] =>
[weight] => 392.84
[form] => C18H21ClN4O4
[cas] => 1638497-25-2
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Avanafil Carboxylic Acid Analog
Catalogue No.:PA 28 44570
Molecular Formula : C18H21ClN4O4
Molecular Weight : 392.84
stdClass Object
(
[pname] => R-Avanafil
[catalogue_number] => PA 28 44580
[category_ids] => ,80,71,78,70,82,79,
[chemical_name] =>
[weight] => 483.95
[form] => C23H26ClN7O3
[cas] => 1638497-26-3
[pslug] => 1638497-26-3-r-avanafil-pa2844580
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Catalogue No.:PA 28 44580
Molecular Formula : C23H26ClN7O3
Molecular Weight : 483.95
stdClass Object
(
[pname] => Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylsulfinyl)pyrimidine-5-carboxylate
[catalogue_number] => PA 28 44600
[category_ids] => ,80,71,78,70,82,79,88,
[chemical_name] =>
[weight] => 383.85
[form] => C16H18ClN3O4S
[cas] => 330785-82-5
[pslug] => 330785-82-5-ethyl-4-3-chloro-4-methoxybenzyl-amino-2-methylsulfinyl-pyrimidine-5-carboxylate-pa2844600
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Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylsulfinyl)pyrimidine-5-carboxylate
Catalogue No.:PA 28 44600
Molecular Formula : C16H18ClN3O4S
Molecular Weight : 383.85
stdClass Object
(
[pname] => Avanafi Thiomethyl Analog
[catalogue_number] => PA 28 44610
[category_ids] => ,80,71,78,70,82,79,88,
[chemical_name] =>
[weight] => 430.91
[form] => C19H19ClN6O2S
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Avanafi Thiomethyl Analog
Catalogue No.:PA 28 44610
Molecular Formula : C19H19ClN6O2S
Molecular Weight : 430.91
stdClass Object
(
[pname] => Avanafi Dichloro Analog
[catalogue_number] => PA 28 44620
[category_ids] => ,80,71,78,70,82,79,75,
[chemical_name] =>
[weight] => 518.4
[form] => C23H25Cl2N7O3
[cas] => 2520113-66-8
[pslug] => 2520113-66-8-avanafi-dichloro-analog-pa2844620
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stdClass Object
(
[pname] => (1,4,5,6-Tetrahydropyrimidin-2-yl)methanamine
[catalogue_number] => PA 28 44630
[category_ids] => ,80,79,84,75,
[chemical_name] =>
[weight] => 113.16
[form] => C5H11N3
[cas] => 759408-08-7
[pslug] => 759408-08-7-1-4-5-6-tetrahydropyrimidin-2-yl-methanamine-pa2844630
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(1,4,5,6-Tetrahydropyrimidin-2-yl)methanamine
Catalogue No.:PA 28 44630
Molecular Formula : C5H11N3
Molecular Weight : 113.16
stdClass Object
(
[pname] => 4-((4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)amino)-5-hydroxypentanoic Acid
[catalogue_number] => PA 28 44640
[category_ids] => ,80,71,78,70,82,79,75,
[chemical_name] =>
[weight] => 515.95
[form] => C23H26ClN7O5
[cas] => 2748151-94-0
[pslug] => 2748151-94-0-4-4-3-chloro-4-methoxybenzyl-amino-5-pyrimidin-2-ylmethyl-carbamoyl-pyrimidin-2-yl-amino-5-hydroxypentanoic-acid-pa2844640
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4-((4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)amino)-5-hydroxypentanoic Acid
Catalogue No.:PA 28 44640
Molecular Formula : C23H26ClN7O5
Molecular Weight : 515.95
stdClass Object
(
[pname] => 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid
[catalogue_number] => PA 28 44650
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[chemical_name] =>
[weight] => 339.8
[form] => C14H14ClN3O3S
[cas] => 330786-34-0
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4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid
stdClass Object
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[pname] => Avanafil Isopropyl Amide Analog
[catalogue_number] => PA 28 44660
[category_ids] => ,80,71,78,70,82,79,75,
[chemical_name] =>
[weight] => 433.93
[form] => C21H28ClN5O3
[cas] => 2520114-11-6
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Avanafil Isopropyl Amide Analog
Catalogue No.:PA 28 44660
Molecular Formula : C21H28ClN5O3
Molecular Weight : 433.93
stdClass Object
(
[pname] => Avanafil-13C5,15N
[catalogue_number] => PA STI 009310
[category_ids] => ,80,69,71,78,70,82,98,
[chemical_name] =>
[weight] => 489.91
[form] => C1813C5H26ClN615NO3
[cas] => 1276495-36-3
[pslug] => 1276495-36-3-avanafil-13c5-15n-pasti009310
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Catalogue No.:PA STI 009310
Molecular Formula : C1813C5H26ClN615NO3
Molecular Weight : 489.91
stdClass Object
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[pname] => (S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic Acid
[catalogue_number] => PA 28 0441017
[category_ids] => 92,71,69,70,78,80,82
[chemical_name] =>
[weight] => 392.84
[form] => C18H21ClN4O4
[cas] => 330785-84-7
[pslug] => 330785-84-7-s-4-3-chloro-4-methoxybenzyl-amino-2-2-hydroxymethyl-pyrrolidin-1-yl-pyrimidine-5-carboxylic-acid-pa280441017
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(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic Acid
Catalogue No.:PA 28 0441017
Molecular Formula : C18H21ClN4O4
Molecular Weight : 392.84
stdClass Object
(
[pname] => 4-(Diethylamino)-4'-sulfoazobenzene
[catalogue_number] => PA 28 0441018
[category_ids] => ,80,69,71,78,82,92,
[chemical_name] =>
[weight] => 333.41
[form] => C16H19N3O3S
[cas] => 6287-12-3
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4-(Diethylamino)-4'-sulfoazobenzene
Catalogue No.:PA 28 0441018
Molecular Formula : C16H19N3O3S
Molecular Weight : 333.41