Sorafenib-impurities | Pharmaffiliates

sorafenib

A tosylate salt of Sorafenib which is a kinase inhibitor drug. It is used for the treatment of kidney, liver and thyroid cancer. It works by inhibiting the VEGFR-2/PDGFR-beta signaling cascade, thereby blocking tumor angiogenesis. Reference standards of Sorafenib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
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    [pname] => Flucofuron
    [catalogue_number] => PA 46 17610
    [category_ids] => ,80,79,78,70,82,
    [chemical_name] => 
    [weight] => 417.13
    [form] => C15H8Cl2F6N2O
    [cas] => 370-50-3
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PA 46 17610

Flucofuron


  • Catalogue No.:PA 46 17610

  • CAS :

    370-50-3

  • Molecular Formula : C15H8Cl2F6N2O

  • Molecular Weight : 417.13

20 % OFF
stdClass Object
(
    [pname] => Sorafenib - API Standards 
    [catalogue_number] => PA 46 17000
    [category_ids] => ,79,81,78,70,82,
    [chemical_name] => 
    [weight] => 464.82
    [form] => C21H16ClF3N4O3
    [cas] => 284461-73-0
    [pslug] => 284461-73-0-sorafenib-api-pa4617000
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PA 46 17000

Sorafenib - API Standards


  • Catalogue No.:PA 46 17000

  • CAS :

    284461-73-0

  • Molecular Formula : C21H16ClF3N4O3

  • Molecular Weight : 464.82

stdClass Object
(
    [pname] => 2-(4-(4-(3-(2-Chloro-3-(Trifluoromethyl)phenyl)ureido)Phenoxy)-6-Methylpicolinamido)-4-Methylbenzenesulfonic Acid
    [catalogue_number] => PA 46 17510
    [category_ids] => 82,81,79,78,70
    [chemical_name] => 
    [weight] => 635.01
    [form] => C28H22ClF3N4O6S
    [cas] => NA
    [pslug] => 2-4-4-3-2-chloro-3-trifluoromethyl-phenyl-ureido-phenoxy-6-methylpicolinamido-4-methylbenzenesulfonic-acid-pa4617510
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PA 46 17510

2-(4-(4-(3-(2-Chloro-3-(Trifluoromethyl)phenyl)ureido)Phenoxy)-6-Methylpicolinamido)-4-Methylbenzenesulfonic Acid


  • Catalogue No.:PA 46 17510

  • CAS :

    NA

  • Molecular Formula : C28H22ClF3N4O6S

  • Molecular Weight : 635.01

stdClass Object
(
    [pname] => 4-Chloro-N-methylpyridine-2-carboxamide Hydrochloride
    [catalogue_number] => PA 19 69520
    [category_ids] => ,79,80,71,
    [chemical_name] => 
    [weight] => 207.06
    [form] => C7H8Cl2N2O
    [cas] => 882167-77-3
    [pslug] => 882167-77-3-4-chloro-n-methylpyridine-2-carboxamide-hydrochloride-pa1969520
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PA 19 69520

4-Chloro-N-methylpyridine-2-carboxamide Hydrochloride


  • Catalogue No.:PA 19 69520

  • CAS :

    882167-77-3

  • Molecular Formula : C7H8Cl2N2O

  • Molecular Weight : 207.06

stdClass Object
(
    [pname] => Sorafenib β-D-Glucuronide
    [catalogue_number] => PA 19 69540
    [category_ids] => ,70,71,75,79,80,82,89,95,
    [chemical_name] => 
    [weight] => 640.95
    [form] => C27H24ClF3N4O9
    [cas] => 1130164-93-0
    [pslug] => 1130164-93-0-sorafenib-beta-d-glucuronide-pa1969540
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PA 19 69540

Sorafenib β-D-Glucuronide


  • Catalogue No.:PA 19 69540

  • CAS :

    1130164-93-0

  • Molecular Formula : C27H24ClF3N4O9

  • Molecular Weight : 640.95

stdClass Object
(
    [pname] => Sorafenib Hemi-Tosylate
    [catalogue_number] => PA 19 69550
    [category_ids] => 89,80,79,75,71,82,70
    [chemical_name] => 
    [weight] => 464.83
    [form] => C21H16ClF3N4O3 .1/2 C7H8O3S
    [cas] => 2056030-06-7
    [pslug] => 2056030-06-7-sorafenib-hemi-tosylate-pa1969550
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PA 19 69550

Sorafenib Hemi-Tosylate


  • Catalogue No.:PA 19 69550

  • CAS :

    2056030-06-7

  • Molecular Formula : C21H16ClF3N4O3 .1/2 C7H8O3S

  • Molecular Weight : 464.83

stdClass Object
(
    [pname] => 4-Chloro-N-methylpyridine-2-carboxamide
    [catalogue_number] => PA 46 17620
    [category_ids] => ,79,80,71,
    [chemical_name] => 
    [weight] => 170.6
    [form] => C7H7ClN2O
    [cas] => 220000-87-3
    [pslug] => 220000-87-3-4-chloro-n-methylpyridine-2-carboxamide-pa4617620
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PA 46 17620

4-Chloro-N-methylpyridine-2-carboxamide


  • Catalogue No.:PA 46 17620

  • CAS :

    220000-87-3

  • Molecular Formula : C7H7ClN2O

  • Molecular Weight : 170.6

stdClass Object
(
    [pname] => N-Desmethyl Sorafenib
    [catalogue_number] => PA 46 17630
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 450.8
    [form] => C20H14ClF3N4O3
    [cas] => 284461-74-1
    [pslug] => 284461-74-1-n-desmethyl-sorafenib-pa4617630
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PA 46 17630

N-Desmethyl Sorafenib


  • Catalogue No.:PA 46 17630

  • CAS :

    284461-74-1

  • Molecular Formula : C20H14ClF3N4O3

  • Molecular Weight : 450.8

stdClass Object
(
    [pname] => 1,3-bis(6-Chloro-2',3'-difluoro-[1,1'-biphenyl]-3-yl)urea
    [catalogue_number] => PA 46 17640
    [category_ids] => 81,79,71,80,70,82,78
    [chemical_name] => 
    [weight] => 505.29
    [form] => C25H14Cl2F4N2O
    [cas] => 2514724-45-7
    [pslug] => 2514724-45-7-1-3-bis-6-chloro-2-3-difluoro-1-1-biphenyl-3-yl-urea-pa4617640
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PA 46 17640

1,3-bis(6-Chloro-2',3'-difluoro-[1,1'-biphenyl]-3-yl)urea


  • Catalogue No.:PA 46 17640

  • CAS :

    2514724-45-7

  • Molecular Formula : C25H14Cl2F4N2O

  • Molecular Weight : 505.29

stdClass Object
(
    [pname] => Methyl 4-(4-aminophenoxy)picolinate
    [catalogue_number] => PA 46 0171012
    [category_ids] => ,79,81,78,70,82,
    [chemical_name] => 
    [weight] => 244.25
    [form] => C13H12N2O3
    [cas] => 757251-59-5
    [pslug] => 757251-59-5-methyl-4-4-aminophenoxy-picolinate-pa460171012
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PA 46 0171012

Methyl 4-(4-aminophenoxy)picolinate


  • Catalogue No.:PA 46 0171012

  • CAS :

    757251-59-5

  • Molecular Formula : C13H12N2O3

  • Molecular Weight : 244.25

stdClass Object
(
    [pname] => Sorafenib Carboxylic Acid Methyl Ester
    [catalogue_number] => PA 46 0171013
    [category_ids] => ,79,81,78,70,82,
    [chemical_name] => 
    [weight] => 465.81
    [form] => C21H15ClF3N3O4
    [cas] => 573673-43-5
    [pslug] => 573673-43-5-sorafenib-carboxylic-acid-methyl-ester-pa460171013
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PA 46 0171013

Sorafenib Carboxylic Acid Methyl Ester


  • Catalogue No.:PA 46 0171013

  • CAS :

    573673-43-5

  • Molecular Formula : C21H15ClF3N3O4

  • Molecular Weight : 465.81

stdClass Object
(
    [pname] => 1-(4-Ethoxy-3-(trifluoromethyl)phenyl)-3-(2-(3-(hydroxymethyl)piperidin-1-yl)ethyl)urea
    [catalogue_number] => PA 46 0171015
    [category_ids] => ,79,81,78,70,82,
    [chemical_name] => 
    [weight] => 389.42
    [form] => C18H26F3N3O3
    [cas] => 1567296-47-2
    [pslug] => 1567296-47-2-1-4-ethoxy-3-trifluoromethyl-phenyl-3-2-3-hydroxymethyl-piperidin-1-yl-ethyl-urea-pa460171015
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PA 46 0171015

1-(4-Ethoxy-3-(trifluoromethyl)phenyl)-3-(2-(3-(hydroxymethyl)piperidin-1-yl)ethyl)urea


  • Catalogue No.:PA 46 0171015

  • CAS :

    1567296-47-2

  • Molecular Formula : C18H26F3N3O3

  • Molecular Weight : 389.42

stdClass Object
(
    [pname] => N-Methyl-4-(methylamino)picolinamide
    [catalogue_number] => PA 46 0171016
    [category_ids] => ,79,81,78,70,82,
    [chemical_name] => 
    [weight] => 165.2
    [form] => C8H11N3O
    [cas] => 1065074-98-7
    [pslug] => 1065074-98-7-n-methyl-4-methylamino-picolinamide-pa460171016
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PA 46 0171016

N-Methyl-4-(methylamino)picolinamide


  • Catalogue No.:PA 46 0171016

  • CAS :

    1065074-98-7

  • Molecular Formula : C8H11N3O

  • Molecular Weight : 165.2

stdClass Object
(
    [pname] => 4,6-Dichloro-N-methylpicolinamide
    [catalogue_number] => PA 46 0171017
    [category_ids] => ,79,81,78,70,82,
    [chemical_name] => 
    [weight] => 205.04
    [form] => C7H6Cl2N2O
    [cas] => 1379324-09-0
    [pslug] => 1379324-09-0-4-6-dichloro-n-methylpicolinamide-pa460171017
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PA 46 0171017

4,6-Dichloro-N-methylpicolinamide


  • Catalogue No.:PA 46 0171017

  • CAS :

    1379324-09-0

  • Molecular Formula : C7H6Cl2N2O

  • Molecular Weight : 205.04

stdClass Object
(
    [pname] => Sorafenib-D4
    [catalogue_number] => PA STI 089851
    [category_ids] => ,98,79,81,78,70,82,
    [chemical_name] => 
    [weight] => 468.85
    [form] => C21H12D4ClF3N4O3
    [cas] => 1207560-07-3
    [pslug] => 1207560-07-3-sorafenib-d4-pasti089851
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PA STI 089851

Sorafenib-D4


  • Catalogue No.:PA STI 089851

  • CAS :

    1207560-07-3

  • Molecular Formula : C21H12D4ClF3N4O3

  • Molecular Weight : 468.85