An antihypertensive drug, Sacubitril is used in combination with valsartan for the treatment of heart ailments. A prodrug of sacubitrilat which is an inhibitor of enzyme neprilysin, which aids the degradation of blood pressure-lowering peptides, atrial and brain natriuretic peptide.Reference standards of Sacubitril API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => Sacubitrilat [catalogue_number] => PA 19 66580 [category_ids] => 70,75,78,79,80,82 [chemical_name] => [weight] => 383.44 [form] => C22H25NO5 [cas] => 149709-44-4 [pslug] => 149709-44-4-sacubitrilat-pa1966580 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 66580
CAS :
Molecular Formula : C22H25NO5
Molecular Weight : 383.44
stdClass Object ( [pname] => Sacubitril mixture with Valsartan [catalogue_number] => PA 19 66600 [category_ids] => 82,80,79,78,75,71,70 [chemical_name] => [weight] => 847.01 [form] => C48H58N6O8 [cas] => 1360873-85-3 [pslug] => 1360873-85-3-sacubitril-mixture-with-valsartan-api-standards-pa1966600 [latest_product] => 0 [linkproducts] => 1 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 66600
Molecular Formula : C48H58N6O8
Molecular Weight : 847.01
stdClass Object ( [pname] => Sacubitril Calcium [catalogue_number] => PA 19 66610 [category_ids] => ,80,75,70,82,78,79,71, [chemical_name] => [weight] => 430.52 [form] => C24H28NO5 ·0.5Ca [cas] => 1369773-39-6 [pslug] => 1369773-39-6-sacubitril-calcium-pa1966610 [latest_product] => 0 [linkproducts] => 1 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 66610
Molecular Formula : C24H28NO5 ·0.5Ca
Molecular Weight : 430.52
stdClass Object ( [pname] => Sacubitril (3R,5S)-Pyrrolidinone Impurity [catalogue_number] => PA 19 66620 [category_ids] => 82,80,79,78,75,70 [chemical_name] => [weight] => 265.35 [form] => C18H19NO [cas] => 1038924-70-7 [pslug] => 1038924-70-7-sacubitril-3r-5s-pyrrolidinone-impurity-pa1966620 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 66620
Molecular Formula : C18H19NO
Molecular Weight : 265.35
stdClass Object ( [pname] => (R,E)-5-([1,1-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic Acid [catalogue_number] => PA 19 66630 [category_ids] => ,80,75,70,82,78,79, [chemical_name] => [weight] => 379.5 [form] => C24H29NO3 [cas] => 1012341-48-8 [pslug] => 1012341-48-8-r-e-5-1-1-biphenyl-4-yl-4-tert-butoxycarbonyl-amino-2-methylpent-2-enoic-acid-pa1966630 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 66630
Molecular Formula : C24H29NO3
Molecular Weight : 379.5
stdClass Object ( [pname] => (R,E)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoate [catalogue_number] => PA 19 66640 [category_ids] => 80,79,70,82,78,75 [chemical_name] => [weight] => 409.53 [form] => C25H31NO4 [cas] => 1817838-91-7 [pslug] => 1817838-91-7-r-e-ethyl-5-1-1-biphenyl-4-yl-4-tert-butoxycarbonyl-amino-2-methylpent-2-enoate-pa1966640 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 66640
Molecular Formula : C25H31NO4
Molecular Weight : 409.53
stdClass Object ( [pname] => Methyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate Hydrochloride [catalogue_number] => PA 19 66650 [category_ids] => ,80,75,70,82,78,79, [chemical_name] => [weight] => 333.86 [form] => C19H24ClNO2 [cas] => 1933501-50-8 [pslug] => 1933501-50-8-methyl-2r-4s-5-1-1-biphenyl-4-yl-4-amino-2-methylpentanoate-hydrochloride-pa1966650 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 66650
Molecular Formula : C19H24ClNO2
Molecular Weight : 333.86
stdClass Object ( [pname] => (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride [catalogue_number] => PA 19 66660 [category_ids] => ,80,75,70,82,78,79, [chemical_name] => [weight] => 347.88 [form] => C20H26ClNO2 [cas] => 149690-12-0 [pslug] => 149690-12-0-2r-4s-4-amino-5-biphenyl-4-yl-2-methylpentanoic-acid-ethyl-ester-hydrochloride-pa1966660 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 66660
Molecular Formula : C20H26ClNO2
Molecular Weight : 347.88
stdClass Object ( [pname] => Ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoate [catalogue_number] => PA 19 66670 [category_ids] => 82,80,79,78,75,70 [chemical_name] => [weight] => 411.54 [form] => C25H33NO4 [cas] => 149709-60-4 [pslug] => 149709-60-4-ethyl-2r-4s-5-1-1-biphenyl-4-yl-4-tert-butoxycarbonyl-amino-2-methylpentanoate-pa1966670 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 66670
Molecular Formula : C25H33NO4
Molecular Weight : 411.54
stdClass Object ( [pname] => (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpentanoic Acid Hydrochloride [catalogue_number] => PA 19 66680 [category_ids] => ,80,75,70,82,78,79, [chemical_name] => [weight] => 319.83 [form] => C18H22ClNO2 [cas] => 1038924-71-8 [pslug] => 1038924-71-8-2r-4s-5-1-1-biphenyl-4-yl-4-amino-2-methylpentanoic-acid-hydrochloride-pa1966680 [latest_product] => 0 [linkproducts] => 1 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 66680
Molecular Formula : C18H22ClNO2
Molecular Weight : 319.83
stdClass Object ( [pname] => Ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-acetamido-2-methylpentanoate [catalogue_number] => PA 19 66690 [category_ids] => ,80,75,70,82,78,79, [chemical_name] => [weight] => 353.46 [form] => C22H27NO3 [cas] => NA [pslug] => ethyl-2r-4s-5-1-1-biphenyl-4-yl-4-acetamido-2-methylpentanoate-pa1966690 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 66690
Molecular Formula : C22H27NO3
Molecular Weight : 353.46
stdClass Object ( [pname] => 2,5-Dioxopyrrolidine Sacubitril [catalogue_number] => PA 19 66700 [category_ids] => ,80,75,70,82,78,79, [chemical_name] => [weight] => 393.48 [form] => C24H27NO4 [cas] => 1038924-97-8 [pslug] => 1038924-97-8-2-5-dioxopyrrolidine-sacubitril-pa1966700 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 66700
Molecular Formula : C24H27NO4
Molecular Weight : 393.48
stdClass Object ( [pname] => ((R)-2-Biphenyl-4-yl-1-formylethyl)carbamic Acid t-butyl Ester [catalogue_number] => PA 19 66710 [category_ids] => ,80,75,70,82,78,79, [chemical_name] => [weight] => 325.41 [form] => C20H23NO3 [cas] => 149709-58-0 [pslug] => 149709-58-0-r-2-biphenyl-4-yl-1-formylethyl-carbamic-acid-t-butyl-ester-pa1966710 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 66710
Molecular Formula : C20H23NO3
Molecular Weight : 325.41
stdClass Object ( [pname] => (R)-tert-Butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate [catalogue_number] => PA 19 66720 [category_ids] => 82,80,79,78,75,70 [chemical_name] => [weight] => 327.42 [form] => C20H25NO3 [cas] => 1426129-50-1 [pslug] => 1426129-50-1-r-tert-butyl-1-1-1-biphenyl-4-yl-3-hydroxypropan-2-yl-carbamate-pa1966720 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 66720
Molecular Formula : C20H25NO3
Molecular Weight : 327.42
stdClass Object ( [pname] => Ethyl (R)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoate [catalogue_number] => PA 19 0661046 [category_ids] => ,80,79,70,82,78,75, [chemical_name] => [weight] => 409.53 [form] => C25H31NO4 [cas] => 149709-59-1 [pslug] => 149709-59-1-ethyl-r-5-1-1-biphenyl-4-yl-4-tert-butoxycarbonyl-amino-2-methylpent-2-enoate-pa190661046 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 0661046
stdClass Object ( [pname] => Ethyl (S,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoate [catalogue_number] => PA 19 0661056 [category_ids] => ,80,79,70,82,78,75, [chemical_name] => [weight] => 409.53 [form] => C25H31NO4 [cas] => 2131788-25-3 [pslug] => 2131788-25-3-ethyl-s-e-5-1-1-biphenyl-4-yl-4-tert-butoxycarbonyl-amino-2-methylpent-2-enoate-pa190661056 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 0661056
stdClass Object ( [pname] => (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(3-carboxy-N-nitrosopropanamido)-2-methylpentanoic Acid [catalogue_number] => PA 19 0661062 [category_ids] => ,70,75,78,79,80,82,162, [chemical_name] => [weight] => 412.44 [form] => C22H24N2O6 [cas] => NA [pslug] => 2r-4s-5-1-1-biphenyl-4-yl-4-3-carboxy-n-nitrosopropanamido-2-methylpentanoic-acid-pa190661062 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 0661062
Molecular Formula : C22H24N2O6
Molecular Weight : 412.44
stdClass Object ( [pname] => (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)(nitroso)amino)-2-methylpentanoic Acid [catalogue_number] => PA 19 0661063 [category_ids] => ,70,75,78,79,80,82,162, [chemical_name] => [weight] => 412.49 [form] => C23H28N2O5 [cas] => NA [pslug] => 2r-4s-5-1-1-biphenyl-4-yl-4-tert-butoxycarbonyl-nitroso-amino-2-methylpentanoic-acid-pa190661063 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 0661063
Molecular Formula : C23H28N2O5
Molecular Weight : 412.49
stdClass Object ( [pname] => tert-Butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate [catalogue_number] => PA 19 0661067 [category_ids] => ,82,80,79,78,75,70, [chemical_name] => [weight] => 327.42 [form] => C20H25NO3 [cas] => 1127490-74-7 [pslug] => 1127490-74-7-tert-butyl-1-1-1-biphenyl-4-yl-3-hydroxypropan-2-yl-carbamate-pa190661067 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 0661067
stdClass Object ( [pname] => Ethyl (2S,4R)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoate [catalogue_number] => PA 19 0661068 [category_ids] => ,82,80,79,78,75,70, [chemical_name] => [weight] => 411.54 [form] => C25H33NO4 [cas] => NA [pslug] => ethyl-2s-4r-5-1-1-biphenyl-4-yl-4-tert-butoxycarbonyl-amino-2-methylpentanoate-pa190661068 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 0661068
stdClass Object ( [pname] => Ethyl (2R,4R)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoate [catalogue_number] => PA 19 0661069 [category_ids] => ,82,80,79,78,75,70, [chemical_name] => [weight] => 411.54 [form] => C25H33NO4 [cas] => NA [pslug] => ethyl-2r-4r-5-1-1-biphenyl-4-yl-4-tert-butoxycarbonyl-amino-2-methylpentanoate-pa190661069 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 0661069
stdClass Object ( [pname] => tert-Butyl (S)-(1-([1,1'-biphenyl]-4-yl)-3-oxopropan-2-yl)carbamate [catalogue_number] => PA 19 0661070 [category_ids] => ,80,75,70,82,78,79, [chemical_name] => [weight] => 325.41 [form] => C20H23NO3 [cas] => 182192-86-5 [pslug] => 182192-86-5-tert-butyl-s-1-1-1-biphenyl-4-yl-3-oxopropan-2-yl-carbamate-pa190661070 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 0661070
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