neratinib
Neratinib is used as an adjuvant therapy in people with early stage breast cancer in which HER2 is overexpressed, after the person receives treatment with trastuzumab. It is a tyrosine kinase inhibitor anticancer drug. Reference standards of Neratinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
(
[pname] => Neratinib
[catalogue_number] => PA 14 74000
[category_ids] => ,79,80,71,81,78,70,82,
[chemical_name] =>
[weight] => 557.04
[form] => C30H29ClN6O3
[cas] => 698387-09-6
[pslug] => 698387-09-6-neratinib-api-pa1474000
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Catalogue No.:PA 14 74000
Molecular Formula : C30H29ClN6O3
Molecular Weight : 557.04
stdClass Object
(
[pname] => Neratinib-d6
[catalogue_number] => PA STI 067320
[category_ids] => ,79,80,71,98,78,70,82,
[chemical_name] =>
[weight] => 563.08
[form] => C30H23D6ClN6O3
[cas] => 1259519-18-0
[pslug] => 1259519-18-0-neratinib-d6-pasti067320
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Catalogue No.:PA STI 067320
Molecular Formula : C30H23D6ClN6O3
Molecular Weight : 563.08
stdClass Object
(
[pname] => N-Nitroso Neratinib
[catalogue_number] => PA 14 0741006
[category_ids] => ,79,80,71,81,78,70,82,
[chemical_name] =>
[weight] => 586.05
[form] => C30H28ClN7O4
[cas] => NA
[pslug] => n-nitroso-neratinib-pa140741006
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Catalogue No.:PA 14 0741006
Molecular Formula : C30H28ClN7O4
Molecular Weight : 586.05
stdClass Object
(
[pname] => N-nitroso Desmethyl Neratinib
[catalogue_number] => PA 14 0741009
[category_ids] => ,79,80,71,78,70,82,162,
[chemical_name] =>
[weight] => 572.02
[form] => C29H26ClN7O4
[cas] => 3050754-68-9
[pslug] => 3050754-68-9-n-nitroso-desmethyl-neratinib-pa140741009
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N-nitroso Desmethyl Neratinib
Catalogue No.:PA 14 0741009
Molecular Formula : C29H26ClN7O4
Molecular Weight : 572.02
stdClass Object
(
[pname] => N-(4-Chloro-3-cyano-7-ethoxyquinolin-6-yl)acetamide
[catalogue_number] => PA 14 0741010
[category_ids] => ,79,80,71,81,78,70,82,
[chemical_name] =>
[weight] => 289.72
[form] => C14H12ClN3O2
[cas] => 848133-76-6
[pslug] => 848133-76-6-n-4-chloro-3-cyano-7-ethoxyquinolin-6-yl-acetamide-pa140741010
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N-(4-Chloro-3-cyano-7-ethoxyquinolin-6-yl)acetamide
Catalogue No.:PA 14 0741010
Molecular Formula : C14H12ClN3O2
Molecular Weight : 289.72
stdClass Object
(
[pname] => 3-Chloro-4-(pyridin-2-ylmethoxy)aniline
[catalogue_number] => PA 14 0741011
[category_ids] => ,79,80,71,81,78,70,82,
[chemical_name] =>
[weight] => 234.68
[form] => C12H11ClN2O
[cas] => 524955-09-7
[pslug] => 524955-09-7-3-chloro-4-pyridin-2-ylmethoxy-aniline-pa140741011
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3-Chloro-4-(pyridin-2-ylmethoxy)aniline
Catalogue No.:PA 14 0741011
Molecular Formula : C12H11ClN2O
Molecular Weight : 234.68