Cabozantinib-impurities | Pharmaffiliates

cabozantinib

Cabozantinib is used in two forms. A capsule form is used since 2012 to treat medullary thyroid cancer and a tablet form is used since 2016 as a second line treatment for renal cell carcinoma.. Reference standards of Cabozantinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

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    [pname] => Cabozantinib - API Standards 
    [catalogue_number] => PA 30 62000
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    [chemical_name] => 
    [weight] => 501.51
    [form] => C28H24FN3O5
    [cas] => 849217-68-1
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PA 30 62000

Cabozantinib - API Standards


  • Catalogue No.:PA 30 62000

  • CAS :

    849217-68-1

  • Molecular Formula : C28H24FN3O5

  • Molecular Weight : 501.51

stdClass Object
(
    [pname] => Cabozantinib Amine Analog
    [catalogue_number] => PA 30 62550
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 296.32
    [form] => C17H16N2O3
    [cas] => 190728-25-7
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PA 30 62550

Cabozantinib Amine Analog


  • Catalogue No.:PA 30 62550

  • CAS :

    190728-25-7

  • Molecular Formula : C17H16N2O3

  • Molecular Weight : 296.32

20 % OFF
stdClass Object
(
    [pname] => 1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic Acid
    [catalogue_number] => PA 30 62600
    [category_ids] => ,80,79,89,71,
    [chemical_name] => 
    [weight] => 223.2
    [form] => C11H10FNO3
    [cas] => 849217-48-7
    [pslug] => 849217-48-7-1-4-fluorophenyl-carbamoyl-cyclopropanecarboxylic-acid-pa3062600
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PA 30 62600

1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic Acid


  • Catalogue No.:PA 30 62600

  • CAS :

    849217-48-7

  • Molecular Formula : C11H10FNO3

  • Molecular Weight : 223.2

stdClass Object
(
    [pname] => N-(4-Fluorophenyl)-n'-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide
    [catalogue_number] => PA 30 62610
    [category_ids] => ,80,79,89,71,78,82,70,
    [chemical_name] => 
    [weight] => 314.31
    [form] => C17H15FN2O3
    [cas] => 849217-60-3
    [pslug] => 849217-60-3-n-4-fluorophenyl-n-4-hydroxyphenyl-cyclopropane-1-1-dicarboxamide-pa3062610
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PA 30 62610

N-(4-Fluorophenyl)-n'-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide


  • Catalogue No.:PA 30 62610

  • CAS :

    849217-60-3

  • Molecular Formula : C17H15FN2O3

  • Molecular Weight : 314.31

stdClass Object
(
    [pname] => Cabozantinib Dimer Impurity
    [catalogue_number] => PA 30 62620
    [category_ids] => 82,80,79,78,71,70
    [chemical_name] => 
    [weight] => 646.65
    [form] => C36H30N4O8
    [cas] => 2832439-31-1
    [pslug] => 2832439-31-1-cabozantinib-dimer-impurity-pa3062620
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PA 30 62620

Cabozantinib Dimer Impurity


  • Catalogue No.:PA 30 62620

  • CAS :

    2832439-31-1

  • Molecular Formula : C36H30N4O8

  • Molecular Weight : 646.65

stdClass Object
(
    [pname] => Cabozantinib-d4
    [catalogue_number] => PA STI 089396
    [category_ids] => ,98,79,80,71,78,70,82,89,
    [chemical_name] => 
    [weight] => 505.54
    [form] => C28H20D4FN3O5
    [cas] => 1802168-53-1
    [pslug] => 1802168-53-1-cabozantinib-d4-pasti089396
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PA STI 089396

Cabozantinib-d4


  • Catalogue No.:PA STI 089396

  • CAS :

    1802168-53-1

  • Molecular Formula : C28H20D4FN3O5

  • Molecular Weight : 505.54

stdClass Object
(
    [pname] => N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-6,7-dimethoxyquinolin-4-amine
    [catalogue_number] => PA 30 0621022
    [category_ids] => ,75,76,79,80,71,78,82,
    [chemical_name] => 
    [weight] => 483.52
    [form] => C28H25N3O5
    [cas] => NA
    [pslug] => n-4-6-7-dimethoxyquinolin-4-yl-oxy-phenyl-6-7-dimethoxyquinolin-4-amine-pa300621022
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PA 30 0621022

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-6,7-dimethoxyquinolin-4-amine


  • Catalogue No.:PA 30 0621022

  • CAS :

    NA

  • Molecular Formula : C28H25N3O5

  • Molecular Weight : 483.52

stdClass Object
(
    [pname] => (E)-N-(3-(4,5-Dimethoxy-2-nitrophenyl)-3-oxoprop-1-en-1-yl)-N-methylnitrous amide
    [catalogue_number] => PA 30 0621032
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 295.25
    [form] => C12H13N3O6
    [cas] => NA
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PA 30 0621032

(E)-N-(3-(4,5-Dimethoxy-2-nitrophenyl)-3-oxoprop-1-en-1-yl)-N-methylnitrous amide


  • Catalogue No.:PA 30 0621032

  • CAS :

    NA

  • Molecular Formula : C12H13N3O6

  • Molecular Weight : 295.25

stdClass Object
(
    [pname] => 5-(((3,4-Dimethoxyphenyl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione
    [catalogue_number] => PA 30 0621034
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 307.3
    [form] => C15H17NO6
    [cas] => 213699-53-7
    [pslug] => 213699-53-7-5-3-4-dimethoxyphenyl-amino-methylene-2-2-dimethyl-1-3-dioxane-4-6-dione-pa300621034
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PA 30 0621034

5-(((3,4-Dimethoxyphenyl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione


  • Catalogue No.:PA 30 0621034

  • CAS :

    213699-53-7

  • Molecular Formula : C15H17NO6

  • Molecular Weight : 307.3

stdClass Object
(
    [pname] => Cabozantinib Methyl Ester Analog
    [catalogue_number] => PA 30 0621035
    [category_ids] => ,82,80,79,78,71,70,
    [chemical_name] => 
    [weight] => 422.43
    [form] => C23H22N2O6
    [cas] => 1584696-82-1
    [pslug] => 1584696-82-1-cabozantinib-methyl-ester-analog-pa300621035
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PA 30 0621035

Cabozantinib Methyl Ester Analog


  • Catalogue No.:PA 30 0621035

  • CAS :

    1584696-82-1

  • Molecular Formula : C23H22N2O6

  • Molecular Weight : 422.43

stdClass Object
(
    [pname] => Cabozantinib Ethyl Ester Analog
    [catalogue_number] => PA 30 0621036
    [category_ids] => ,82,80,79,78,71,70,
    [chemical_name] => 
    [weight] => 436.46
    [form] => C24H24N2O6
    [cas] => 1584696-80-9
    [pslug] => 1584696-80-9-cabozantinib-ethyl-ester-analog-pa300621036
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PA 30 0621036

Cabozantinib Ethyl Ester Analog


  • Catalogue No.:PA 30 0621036

  • CAS :

    1584696-80-9

  • Molecular Formula : C24H24N2O6

  • Molecular Weight : 436.46

stdClass Object
(
    [pname] => N1-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N3-(4-fluorophenyl)-2-(2-hydroxyethyl)malonamide
    [catalogue_number] => PA 30 0621037
    [category_ids] => ,79,80,71,78,70,82,89,
    [chemical_name] => 
    [weight] => 519.53
    [form] => C28H26FN3O6
    [cas] => NA
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PA 30 0621037

N1-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N3-(4-fluorophenyl)-2-(2-hydroxyethyl)malonamide


  • Catalogue No.:PA 30 0621037

  • CAS :

    NA

  • Molecular Formula : C28H26FN3O6

  • Molecular Weight : 519.53

stdClass Object
(
    [pname] => (2S)-4-(4-((4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)amino)-3-((4-fluorophenyl)carbamoyl)-4-oxobutoxy)-2-hydroxy-4-oxobutanoic Acid
    [catalogue_number] => PA 30 0621038
    [category_ids] => ,79,80,71,78,70,82,89,
    [chemical_name] => 
    [weight] => 635.6
    [form] => C32H30FN3O10
    [cas] => NA
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PA 30 0621038

(2S)-4-(4-((4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)amino)-3-((4-fluorophenyl)carbamoyl)-4-oxobutoxy)-2-hydroxy-4-oxobutanoic Acid


  • Catalogue No.:PA 30 0621038

  • CAS :

    NA

  • Molecular Formula : C32H30FN3O10

  • Molecular Weight : 635.6

stdClass Object
(
    [pname] => N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)-N-methylcyclopropane-1,1-dicarboxamide
    [catalogue_number] => PA 30 0621039
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 515.54
    [form] => C29H26FN3O5
    [cas] => 2458244-61-4
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PA 30 0621039

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)-N-methylcyclopropane-1,1-dicarboxamide


  • Catalogue No.:PA 30 0621039

  • CAS :

    2458244-61-4

  • Molecular Formula : C29H26FN3O5

  • Molecular Weight : 515.54