Bosentan Hydrate is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure. It is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals . Reference standards of Bosentan Hydrate API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
stdClass Object ( [pname] => 4-(tert-Butyl)-N-[6-hydroxy-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl]benzenesulfonamide [catalogue_number] => PA 02 21540 [category_ids] => ,70,71,78,79,80,82,83,85,88, [chemical_name] => [weight] => 507.56 [form] => C25H25N5O5S [cas] => 174227-14-6 [pslug] => 174227-14-6-4-tert-butyl-n-6-hydroxy-5-2-methoxyphenoxy-2-2-bipyrimidin-4-yl-benzenesulfonamide-pa0221540 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 02 21540
CAS :
Molecular Formula : C25H25N5O5S
Molecular Weight : 507.56
stdClass Object ( [pname] => 6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4(3H)-one [catalogue_number] => PA 02 21550 [category_ids] => 88,85,83,82,80,79,78,71,70 [chemical_name] => [weight] => 330.73 [form] => C15H11ClN4O3 [cas] => 1268612-27-6 [pslug] => 1268612-27-6-6-chloro-5-2-methoxyphenoxy-2-2-bipyrimidin-4-3h-one-pa0221550 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 02 21550
Molecular Formula : C15H11ClN4O3
Molecular Weight : 330.73
stdClass Object ( [pname] => 4-(tert-Butyl)-N,N-bis(6-chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide [catalogue_number] => PA 02 21580 [category_ids] => ,79,80,71,85,83,78,70,82,88, [chemical_name] => [weight] => 838.72 [form] => C40H33Cl2N9O6S [cas] => NA [pslug] => 4-tert-butyl-n-n-bis-6-chloro-5-2-methoxyphenoxy-2-2-bipyrimidin-4-yl-benzenesulfonamide-pa0221580 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 02 21580
Molecular Formula : C40H33Cl2N9O6S
Molecular Weight : 838.72
stdClass Object ( [pname] => N,N'-[5-(2-Methoxyphenoxy)[2,2'-bipyrimidine]-4,6-diyl]bis[4-(1,1-dimethylethyl)benzenesulfonamide] [catalogue_number] => PA 02 21590 [category_ids] => ,79,80,71,78,70,82,88, [chemical_name] => [weight] => 702.84 [form] => C35H38N6O6S2 [cas] => 1218951-81-5 [pslug] => 1218951-81-5-n-n-5-2-methoxyphenoxy-2-2-bipyrimidine-4-6-diyl-bis-4-1-1-dimethylethyl-benzenesulfonamide-pa0221590 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 02 21590
Molecular Formula : C35H38N6O6S2
Molecular Weight : 702.84
stdClass Object ( [pname] => 4-(tert-Butyl)-N-(6-methoxy-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide [catalogue_number] => PA 02 21600 [category_ids] => ,79,80,71,85,83,78,70,82,88, [chemical_name] => [weight] => 521.59 [form] => C26H27N5O5S [cas] => NA [pslug] => 4-tert-butyl-n-6-methoxy-5-2-methoxyphenoxy-2-2-bipyrimidin-4-yl-benzenesulfonamide-pa0221600 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 02 21600
Molecular Formula : C26H27N5O5S
Molecular Weight : 521.59
stdClass Object ( [pname] => N-(6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)-4-isopropylbenzenesulfonamide [catalogue_number] => PA 02 21610 [category_ids] => ,79,80,71,85,83,78,70,82,88, [chemical_name] => [weight] => 537.59 [form] => C26H27N5O6S [cas] => 1268612-24-3 [pslug] => 1268612-24-3-n-6-2-hydroxyethoxy-5-2-methoxyphenoxy-2-2-bipyrimidin-4-yl-4-isopropylbenzenesulfonamide-pa0221610 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 02 21610
Molecular Formula : C26H27N5O6S
Molecular Weight : 537.59
stdClass Object ( [pname] => Bosentan Dimer Impurity [catalogue_number] => PA 02 21620 [category_ids] => ,79,80,71,78,70,82,88, [chemical_name] => [weight] => 1041.16 [form] => C52H52N10O10S2 [cas] => 1097263-60-9 [pslug] => 1097263-60-9-bosentan-dimer-impurity-pa0221620 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 02 21620
Molecular Formula : C52H52N10O10S2
Molecular Weight : 1041.16
stdClass Object ( [pname] => 2-tert-Butylbenzenesulfonamide [catalogue_number] => PA 02 21630 [category_ids] => ,79,80,78,70,82,88, [chemical_name] => [weight] => 213.3 [form] => C10H15NO2S [cas] => 193013-72-8 [pslug] => 193013-72-8-2-tert-butylbenzenesulfonamide-pa0221630 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 02 21630
Molecular Formula : C10H15NO2S
Molecular Weight : 213.3
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