A Nintedanib is used in the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer. It is a small molecule kinase inhibitor. Reference standards of Nintedanib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => Methyl (Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate [catalogue_number] => PA 14 0541034 [category_ids] => ,70,75,76,78,82,162, [chemical_name] => [weight] => 568.63 [form] => C31H32N6O5 [cas] => NA [pslug] => methyl-z-3-4-n-methyl-2-4-methylpiperazin-1-yl-acetamido-phenyl-nitroso-amino-phenyl-methylene-2-oxoindoline-6-carboxylate-pa140541034 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 0541034
CAS :
Molecular Formula : C31H32N6O5
Molecular Weight : 568.63
stdClass Object ( [pname] => Methyl (Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-1-nitroso-2-oxoindoline-6-carboxylate [catalogue_number] => PA 14 0541038 [category_ids] => ,69,70,78,82,162, [chemical_name] => [weight] => 568.63 [form] => C31H32N6O5 [cas] => NA [pslug] => methyl-z-3-4-n-methyl-2-4-methylpiperazin-1-yl-acetamido-phenyl-amino-phenyl-methylene-1-nitroso-2-oxoindoline-6-carboxylate-pa140541038 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 0541038
stdClass Object ( [pname] => N-nitroso-N-desmethylnintedanib [catalogue_number] => PA 14 0541039 [category_ids] => ,70,71,78,79,82,162, [chemical_name] => [weight] => 554.61 [form] => C30H30N6O5 [cas] => NA [pslug] => n-nitroso-n-desmethylnintedanib-pa140541039 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 0541039
Molecular Formula : C30H30N6O5
Molecular Weight : 554.61
stdClass Object ( [pname] => Nintedanib 4-Nitrophenyl 2-(4-Nitroso) [catalogue_number] => PA 14 0541042 [category_ids] => ,70,71,78,79,82,162, [chemical_name] => [weight] => 307.31 [form] => C13H17N5O4 [cas] => 2490403-92-2 [pslug] => 2490403-92-2-nintedanib-4-nitrophenyl-2-4-nitroso-pa140541042 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 0541042
Molecular Formula : C13H17N5O4
Molecular Weight : 307.31
stdClass Object ( [pname] => Methyl (Z)-3-(((4-(methylamino)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-5-carboxylate [catalogue_number] => PA 14 0541058 [category_ids] => ,79,71,78,70,82,162, [chemical_name] => [weight] => 428.45 [form] => C24H20N4O4 [cas] => NA [pslug] => methyl-z-3-4-methylamino-phenyl-nitroso-amino-phenyl-methylene-2-oxoindoline-5-carboxylate-pa140541058 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 0541058
Molecular Formula : C24H20N4O4
Molecular Weight : 428.45
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