Ivacaftor is used for the treatment of cystic fibrosis in people having one of several specific mutations in the cystic fibrosis transmembrane conductance regulator protein. It is one of the most expensive drugs. Reference standards of Ivacaftor API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => 1-Nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid [catalogue_number] => PA 09 0401005 [category_ids] => ,70,78,80,82,162, [chemical_name] => [weight] => 218.17 [form] => C10H6N2O4 [cas] => NA [pslug] => 1-nitroso-4-oxo-1-4-dihydroquinoline-3-carboxylic-acid-pa090401005 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401005
CAS :
Molecular Formula : C10H6N2O4
Molecular Weight : 218.17
stdClass Object ( [pname] => N-(4-(Tert-butyl)-3-hydroxyphenyl)-1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxamide [catalogue_number] => PA 09 0401007 [category_ids] => ,70,78,80,82,162, [chemical_name] => [weight] => 365.39 [form] => C20H19N3O4 [cas] => NA [pslug] => n-4-tert-butyl-3-hydroxyphenyl-1-nitroso-4-oxo-1-4-dihydroquinoline-3-carboxamide-pa090401007 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401007
Molecular Formula : C20H19N3O4
Molecular Weight : 365.39
stdClass Object ( [pname] => Ivacaftor Nitroso Impurity [catalogue_number] => PA 09 0401008 [category_ids] => ,70,78,80,82,162, [chemical_name] => [weight] => 421.5 [form] => C24H27N3O4 [cas] => NA [pslug] => ivacaftor-nitroso-impurity-pa090401008 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401008
Molecular Formula : C24H27N3O4
Molecular Weight : 421.5
stdClass Object ( [pname] => N-Nitroso Ivacaftor Ortho Isomer [catalogue_number] => PA 09 0401010 [category_ids] => ,70,78,80,82,162, [chemical_name] => [weight] => 421.5 [form] => C24H27N3O4 [cas] => NA [pslug] => n-nitroso-ivacaftor-ortho-isomer-pa090401010 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401010
stdClass Object ( [pname] => Ethyl 1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylate [catalogue_number] => PA 09 0401011 [category_ids] => ,70,78,80,82,162, [chemical_name] => [weight] => 246.22 [form] => C12H10N2O4 [cas] => NA [pslug] => ethyl-1-nitroso-4-oxo-1-4-dihydroquinoline-3-carboxylate-pa090401011 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401011
Molecular Formula : C12H10N2O4
Molecular Weight : 246.22
stdClass Object ( [pname] => Diethyl 2-((nitroso(phenyl)amino)methylene)malonate [catalogue_number] => PA 09 0401013 [category_ids] => ,78,70,82,162, [chemical_name] => [weight] => 292.29 [form] => C14H16N2O5 [cas] => NA [pslug] => diethyl-2-nitroso-phenyl-amino-methylene-malonate-pa090401013 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401013
Molecular Formula : C14H16N2O5
Molecular Weight : 292.29
stdClass Object ( [pname] => N-(4,6-Di-tert-butyl-3-hydroxy-2-nitrosophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide [catalogue_number] => PA 09 0401014 [category_ids] => ,70,78,80,82,162, [chemical_name] => [weight] => 421.5 [form] => C24H27N3O4 [cas] => NA [pslug] => n-4-6-di-tert-butyl-3-hydroxy-2-nitrosophenyl-4-oxo-1-4-dihydroquinoline-3-carboxamide-pa090401014 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401014
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