Bosutinib is used to treat chronic myeloid leukaemia that has an abnormal chromosome called the Philadelphia chromosome. It is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl and Src kinases with potential antineoplastic activity.. Reference standards of Bosutinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
stdClass Object ( [pname] => 4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-nitrosopiperazin-1-yl)propoxy)quinoline-3-carbonitrile [catalogue_number] => PA 02 0921030 [category_ids] => ,70,71,78,80,81,82,162, [chemical_name] => [weight] => 545.42 [form] => C25H26Cl2N6O4 [cas] => NA [pslug] => 4-2-4-dichloro-5-methoxyphenyl-amino-6-methoxy-7-3-4-nitrosopiperazin-1-yl-propoxy-quinoline-3-carbonitrile-pa020921030 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 02 0921030
CAS :
Molecular Formula : C25H26Cl2N6O4
Molecular Weight : 545.42
stdClass Object ( [pname] => 1-(3-(2-Methoxy-5-nitrophenoxy)propyl)-4-nitrosopiperazine [catalogue_number] => PA 02 0921033 [category_ids] => ,80,71,81,78,70,82,162, [chemical_name] => [weight] => 324.34 [form] => C14H20N4O5 [cas] => NA [pslug] => 1-3-2-methoxy-5-nitrophenoxy-propyl-4-nitrosopiperazine-pa020921033 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 02 0921033
Molecular Formula : C14H20N4O5
Molecular Weight : 324.34
stdClass Object ( [pname] => 2-Cyano-N-(2,4-dichloro-5-methoxyphenyl)-3-((4-methoxy-3-(3-(4-nitrosopiperazin-1-yl)propoxy)phenyl)amino)acrylamide [catalogue_number] => PA 02 0921034 [category_ids] => ,80,71,81,78,70,82,162, [chemical_name] => [weight] => 563.44 [form] => C25H28Cl2N6O5 [cas] => NA [pslug] => 2-cyano-n-2-4-dichloro-5-methoxyphenyl-3-4-methoxy-3-3-4-nitrosopiperazin-1-yl-propoxy-phenyl-amino-acrylamide-pa020921034 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 02 0921034
Molecular Formula : C25H28Cl2N6O5
Molecular Weight : 563.44
stdClass Object ( [pname] => N-(3-Cyano-6-methoxy-7-propoxyquinolin-4-yl)-N-(2,4-dichloro-5-methoxyphenyl)nitrous amide [catalogue_number] => PA 02 0921035 [category_ids] => ,80,71,81,78,70,82,162, [chemical_name] => [weight] => 461.3 [form] => C21H18Cl2N4O4 [cas] => NA [pslug] => n-3-cyano-6-methoxy-7-propoxyquinolin-4-yl-n-2-4-dichloro-5-methoxyphenyl-nitrous-amide-pa020921035 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 02 0921035
Molecular Formula : C21H18Cl2N4O4
Molecular Weight : 461.3
stdClass Object ( [pname] => N,N'-((Propane-1,3-diylbis(oxy))bis(3-cyano-6-methoxyquinoline-7,4-diyl))bis(N-(2,4-dichloro-5-methoxyphenyl)nitrous amide) [catalogue_number] => PA 02 0921036 [category_ids] => ,80,71,81,78,70,82,162, [chemical_name] => [weight] => 878.5 [form] => C39H28Cl4N8O8 [cas] => NA [pslug] => n-n-propane-1-3-diylbis-oxy-bis-3-cyano-6-methoxyquinoline-7-4-diyl-bis-n-2-4-dichloro-5-methoxyphenyl-nitrous-amide-pa020921036 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 02 0921036
Molecular Formula : C39H28Cl4N8O8
Molecular Weight : 878.5
stdClass Object ( [pname] => N,N'-(((Piperazine-1,4-diylbis(propane-3,1-diyl))bis(oxy))bis(3-cyano-6-methoxyquinoline-7,4-diyl))bis(N-(2,4-dichloro-5-methoxyphenyl)nitrous amide) [catalogue_number] => PA 02 0921037 [category_ids] => ,80,71,81,78,70,82,162, [chemical_name] => [weight] => 1004.7 [form] => C46H42Cl4N10O8 [cas] => NA [pslug] => n-n-piperazine-1-4-diylbis-propane-3-1-diyl-bis-oxy-bis-3-cyano-6-methoxyquinoline-7-4-diyl-bis-n-2-4-dichloro-5-methoxyphenyl-nitrous-amide-pa020921037 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 02 0921037
Molecular Formula : C46H42Cl4N10O8
Molecular Weight : 1004.7
stdClass Object ( [pname] => N-(3-Cyano-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yl)-N-(2,4-dichloro-5-methoxyphenyl)nitrous amide [catalogue_number] => PA 02 0921038 [category_ids] => ,80,71,81,78,70,82,162, [chemical_name] => [weight] => 559.45 [form] => C26H28Cl2N6O4 [cas] => NA [pslug] => n-3-cyano-6-methoxy-7-3-4-methylpiperazin-1-yl-propoxy-quinolin-4-yl-n-2-4-dichloro-5-methoxyphenyl-nitrous-amide-pa020921038 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 02 0921038
Molecular Formula : C26H28Cl2N6O4
Molecular Weight : 559.45
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