pyrimethamine
Used for the treatment of toxoplasmosis ( a parasitic disease) and cystoisosporiasis (human intestinal parasitic disease ) in combination with leucovorin. It works by inhibiting the synthesis of RNA and DNA in many species. A dihydrofolate reductase inhibitor.Reference standards of Pyrimethamine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
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[pname] => Pyrimethamine
[catalogue_number] => PA 43 01000
[category_ids] => ,70,71,78,79,82,83,85,
[chemical_name] =>
[weight] => 248.71
[form] => C12H13ClN4
[cas] => 58-14-0
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Catalogue No.:PA 43 01000
Molecular Formula : C12H13ClN4
Molecular Weight : 248.71
stdClass Object
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[pname] => 2-(4-Chlorophenyl)-2-(2-ethyl-1,3-dioxolan-2-yl)acetonitrile
[catalogue_number] => PA 43 01510
[category_ids] => ,79,71,85,83,78,70,82,
[chemical_name] =>
[weight] => 251.71
[form] => C13H14ClNO2
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2-(4-Chlorophenyl)-2-(2-ethyl-1,3-dioxolan-2-yl)acetonitrile
Catalogue No.:PA 43 01510
Molecular Formula : C13H14ClNO2
Molecular Weight : 251.71
stdClass Object
(
[pname] => Pyrimethamine E-isomer
[catalogue_number] => PA 43 01520
[category_ids] => ,79,71,85,83,78,70,82,
[chemical_name] =>
[weight] => 207.66
[form] => C11H10ClNO
[cas] => 118364-47-9
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Catalogue No.:PA 43 01520
Molecular Formula : C11H10ClNO
Molecular Weight : 207.66
stdClass Object
(
[pname] => Pyrimethamine Z-isomer
[catalogue_number] => PA 43 01530
[category_ids] => ,79,71,85,83,78,70,82,
[chemical_name] =>
[weight] => 207.66
[form] => C11H10ClNO
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Catalogue No.:PA 43 01530
Molecular Formula : C11H10ClNO
Molecular Weight : 207.66
stdClass Object
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[pname] => Pyrimethamine E/Z-Mixture
[catalogue_number] => PA 43 01540
[category_ids] => ,79,71,85,83,78,70,82,
[chemical_name] =>
[weight] => 207.66
[form] => C11H10ClNO
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Pyrimethamine E/Z-Mixture
Catalogue No.:PA 43 01540
Molecular Formula : C11H10ClNO
Molecular Weight : 207.66
stdClass Object
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[pname] => Pyrimethamine - Impurity D
[catalogue_number] => PA 43 01560
[category_ids] => ,70,78,80,82,
[chemical_name] =>
[weight] => 251.71
[form] => C13H14ClNO2
[cas] => NA
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Pyrimethamine - Impurity D
Catalogue No.:PA 43 01560
Molecular Formula : C13H14ClNO2
Molecular Weight : 251.71
stdClass Object
(
[pname] => Ethyl 2-(4-chlorophenyl)-3-oxopentanoate
[catalogue_number] => PA 43 01570
[category_ids] => ,92,80,78,70,82,
[chemical_name] =>
[weight] => 254.71
[form] => C13H15ClO3
[cas] => 100713-76-6
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Ethyl 2-(4-chlorophenyl)-3-oxopentanoate
Catalogue No.:PA 43 01570
Molecular Formula : C13H15ClO3
Molecular Weight : 254.71
stdClass Object
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[pname] => (Z)-2-(4-Chlorophenyl)-3-hydroxypent-2-enenitrile
[catalogue_number] => PA 43 01580
[category_ids] => ,92,80,78,70,82,
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[weight] => 207.66
[form] => C11H10ClNO
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(Z)-2-(4-Chlorophenyl)-3-hydroxypent-2-enenitrile
Catalogue No.:PA 43 01580
Molecular Formula : C11H10ClNO
Molecular Weight : 207.66
stdClass Object
(
[pname] => Pyrimethamine - Impurity C
[catalogue_number] => PA 43 0010030
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 151.59
[form] => C8H6ClN
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Pyrimethamine - Impurity C
Catalogue No.:PA 43 0010030
Molecular Formula : C8H6ClN
Molecular Weight : 151.59
stdClass Object
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[pname] => 4-Amino-5-(4-chlorophenyl)-6-ethyl-1,2-dihydropyrimidin-2-one
[catalogue_number] => PA 43 0011001
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[chemical_name] =>
[weight] => 249.7
[form] => C12H12ClN3O
[cas] => 93456-61-2
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4-Amino-5-(4-chlorophenyl)-6-ethyl-1,2-dihydropyrimidin-2-one
stdClass Object
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[pname] => 2-(4-Chlorophenyl)-3-oxobutanenitrile
[catalogue_number] => PA 43 0011002
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 193.63
[form] => C10H8ClNO
[cas] => 5219-07-8
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2-(4-Chlorophenyl)-3-oxobutanenitrile
Catalogue No.:PA 43 0011002
Molecular Formula : C10H8ClNO
Molecular Weight : 193.63
stdClass Object
(
[pname] => 5-(4-Chlorophenyl)-6-ethylpyrimidine-2,4(1H,3H)-dione
[catalogue_number] => PA 43 0011003
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 250.68
[form] => C12H11ClN2O2
[cas] => 2733998-15-5
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5-(4-Chlorophenyl)-6-ethylpyrimidine-2,4(1H,3H)-dione
Catalogue No.:PA 43 0011003
Molecular Formula : C12H11ClN2O2
Molecular Weight : 250.68
stdClass Object
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[pname] => Pyrimethamine - Impurity A
[catalogue_number] => PA 43 0010010
[category_ids] => ,78,70,82,75,
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[weight] => 207.66
[form] => C11H10ClNO
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Pyrimethamine - Impurity A
Catalogue No.:PA 43 0010010
Molecular Formula : C11H10ClNO
Molecular Weight : 207.66
