ponatinib

A multi-targeted tyrosine-kinase inhibitor, Ponatinib is used in treating chronic myeloid leukemia. Shows antiangiogenic and antineoplastic activities.Reference standards of Ponatinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Ponatinib
    [catalogue_number] => PA 16 91000
    [category_ids] => ,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 532.56
    [form] => C29H27F3N6O
    [cas] => 943319-70-8
    [pslug] => 943319-70-8-ponatinib-api-pa1691000
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PA 16 91000

Ponatinib

  • Catalogue No.:PA 16 91000

  • CAS :

    943319-70-8

  • Molecular Formula : C29H27F3N6O

  • Molecular Weight : 532.56

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Similar products 
stdClass Object
(
    [pname] => 3-Ethynylimidazo[1,2-b]pyridazine
    [catalogue_number] => PA 16 91510
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 143.15
    [form] => C8H5N3
    [cas] => 943320-61-4
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PA 16 91510

3-Ethynylimidazo[1,2-b]pyridazine

  • Catalogue No.:PA 16 91510

  • CAS :

    943320-61-4

  • Molecular Formula : C8H5N3

  • Molecular Weight : 143.15

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stdClass Object
(
    [pname] => N-(4-Formyl-3-(trifluoromethyl)phenyl)-3-iodo-4-methylbenzamide
    [catalogue_number] => PA 16 91520
    [category_ids] => ,71,80,79,78,70,82,89,
    [chemical_name] => 
    [weight] => 433.16
    [form] => C16H11F3INO2
    [cas] => 1638193-91-5
    [pslug] => 1638193-91-5-n-4-formyl-3-trifluoromethyl-phenyl-3-iodo-4-methylbenzamide-pa1691520
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PA 16 91520

N-(4-Formyl-3-(trifluoromethyl)phenyl)-3-iodo-4-methylbenzamide

  • Catalogue No.:PA 16 91520

  • CAS :

    1638193-91-5

  • Molecular Formula : C16H11F3INO2

  • Molecular Weight : 433.16

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Details 
stdClass Object
(
    [pname] => N-(4-Formyl-3-(trifluoromethyl)phenyl)-3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzamide
    [catalogue_number] => PA 16 91530
    [category_ids] => ,71,80,79,78,70,82,89,
    [chemical_name] => 
    [weight] => 448.4
    [form] => C24H15F3N4O2
    [cas] => 1638193-92-6
    [pslug] => 1638193-92-6-n-4-formyl-3-trifluoromethyl-phenyl-3-imidazo-1-2-b-pyridazin-3-ylethynyl-4-methylbenzamide-pa1691530
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PA 16 91530

N-(4-Formyl-3-(trifluoromethyl)phenyl)-3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzamide

  • Catalogue No.:PA 16 91530

  • CAS :

    1638193-92-6

  • Molecular Formula : C24H15F3N4O2

  • Molecular Weight : 448.4

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stdClass Object
(
    [pname] => 3-Ethynyl-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide
    [catalogue_number] => PA 16 91540
    [category_ids] => ,71,80,79,78,70,82,89,
    [chemical_name] => 
    [weight] => 415.45
    [form] => C23H24F3N3O
    [cas] => 957147-18-1
    [pslug] => 957147-18-1-3-ethynyl-4-methyl-n-4-4-methylpiperazin-1-yl-methyl-3-trifluoromethyl-phenyl-benzamide-pa1691540
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PA 16 91540

3-Ethynyl-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide

  • Catalogue No.:PA 16 91540

  • CAS :

    957147-18-1

  • Molecular Formula : C23H24F3N3O

  • Molecular Weight : 415.45

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stdClass Object
(
    [pname] => Ponatinib N-Oxide
    [catalogue_number] => PA 16 0911000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 548.57
    [form] => C29H27F3N6O2
    [cas] => 2227480-51-3
    [pslug] => 2227480-51-3-ponatinib-n-oxide-pa160911000
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PA 16 0911000

Ponatinib N-Oxide

  • Catalogue No.:PA 16 0911000

  • CAS :

    2227480-51-3

  • Molecular Formula : C29H27F3N6O2

  • Molecular Weight : 548.57

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Details 
stdClass Object
(
    [pname] => 3,3-(Buta-1,3-diyne-1,4-diyl)bis(4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide);
    [catalogue_number] => PA 16 0911001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 828.9
    [form] => C46H46F6N6O2
    [cas] => 2097674-16-1
    [pslug] => 2097674-16-1-3-3-buta-1-3-diyne-1-4-diyl-bis-4-methyl-n-4-4-methylpiperazin-1-yl-methyl-3-trifluoromethyl-phenyl-benzamide-pa160911001
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PA 16 0911001

3,3-(Buta-1,3-diyne-1,4-diyl)bis(4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide);

  • Catalogue No.:PA 16 0911001

  • CAS :

    2097674-16-1

  • Molecular Formula : C46H46F6N6O2

  • Molecular Weight : 828.9

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stdClass Object
(
    [pname] => 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid
    [catalogue_number] => PA 16 0911002
    [category_ids] => ,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 277.28
    [form] => C16H11N3O2
    [cas] => 1300690-48-5
    [pslug] => 1300690-48-5-3-imidazo-1-2-b-pyridazin-3-ylethynyl-4-methylbenzoic-acid-pa160911002
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PA 16 0911002

3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid

  • Catalogue No.:PA 16 0911002

  • CAS :

    1300690-48-5

  • Molecular Formula : C16H11N3O2

  • Molecular Weight : 277.28

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Details 
stdClass Object
(
    [pname] => Methyl 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoate
    [catalogue_number] => PA 16 0911003
    [category_ids] => ,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 291.31
    [form] => C17H13N3O2
    [cas] => 1356385-96-0
    [pslug] => 1356385-96-0-methyl-3-imidazo-1-2-b-pyridazin-3-ylethynyl-4-methylbenzoate-pa160911003
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PA 16 0911003

Methyl 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoate

  • Catalogue No.:PA 16 0911003

  • CAS :

    1356385-96-0

  • Molecular Formula : C17H13N3O2

  • Molecular Weight : 291.31

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stdClass Object
(
    [pname] => 4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline
    [catalogue_number] => PA 16 0911004
    [category_ids] => ,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 273.3
    [form] => C13H18F3N3
    [cas] => 694499-26-8
    [pslug] => 694499-26-8-4-4-methylpiperazin-1-yl-methyl-3-trifluoromethyl-aniline-pa160911004
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PA 16 0911004

4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline

  • Catalogue No.:PA 16 0911004

  • CAS :

    694499-26-8

  • Molecular Formula : C13H18F3N3

  • Molecular Weight : 273.3

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Details 
stdClass Object
(
    [pname] => 3,5-bis(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide
    [catalogue_number] => PA 16 0911005
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 673.7
    [form] => C37H30F3N9O
    [cas] => NA
    [pslug] => 3-5-bis-imidazo-1-2-b-pyridazin-3-ylethynyl-4-methyl-n-4-4-methylpiperazin-1-yl-methyl-3-trifluoromethyl-phenyl-benzamide-pa160911005
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PA 16 0911005

3,5-bis(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide

  • Catalogue No.:PA 16 0911005

  • CAS :

    NA

  • Molecular Formula : C37H30F3N9O

  • Molecular Weight : 673.7

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Details 
stdClass Object
(
    [pname] => 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-nitrosopiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide
    [catalogue_number] => PA 16 0911006
    [category_ids] => ,71,78,70,82,
    [chemical_name] => 
    [weight] => 547.54
    [form] => C28H24F3N7O2
    [cas] => NA
    [pslug] => 3-imidazo-1-2-b-pyridazin-3-ylethynyl-4-methyl-n-4-4-nitrosopiperazin-1-yl-methyl-3-trifluoromethyl-phenyl-benzamide-pa160911006
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PA 16 0911006

3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-nitrosopiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide

  • Catalogue No.:PA 16 0911006

  • CAS :

    NA

  • Molecular Formula : C28H24F3N7O2

  • Molecular Weight : 547.54

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Details 
stdClass Object
(
    [pname] => 4-((4-Nitrosopiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline
    [catalogue_number] => PA 16 0911007
    [category_ids] => ,71,78,70,82,
    [chemical_name] => 
    [weight] => 288.27
    [form] => C12H15F3N4O
    [cas] => NA
    [pslug] => 4-4-nitrosopiperazin-1-yl-methyl-3-trifluoromethyl-aniline-pa160911007
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PA 16 0911007

4-((4-Nitrosopiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline

  • Catalogue No.:PA 16 0911007

  • CAS :

    NA

  • Molecular Formula : C12H15F3N4O

  • Molecular Weight : 288.27

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CPHI INDIA- 28, 30 November