Bosentan Hydrate-impurities | Pharmaffiliates

bosentan hydrate

Bosentan Hydrate is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure. It is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals . Reference standards of Bosentan Hydrate API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

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    [pname] => Bosentan Hydrate - API Standards 
    [catalogue_number] => PA 02 21000
    [category_ids] => ,80,71,85,83,78,70,82,88,
    [chemical_name] => 
    [weight] => 569.63
    [form] => C27H31N5O7S
    [cas] => 157212-55-0
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PA 02 21000

Bosentan Hydrate - API Standards


  • Catalogue No.:PA 02 21000

  • CAS :

    157212-55-0

  • Molecular Formula : C27H31N5O7S

  • Molecular Weight : 569.63

stdClass Object
(
    [pname] => 4-(tert-Butyl)benzenesulfonamide
    [catalogue_number] => PA 02 21510
    [category_ids] => ,70,71,78,80,82,
    [chemical_name] => 
    [weight] => 213.3
    [form] => C10H15NO2S
    [cas] => 6292-59-7
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PA 02 21510

4-(tert-Butyl)benzenesulfonamide


  • Catalogue No.:PA 02 21510

  • CAS :

    6292-59-7

  • Molecular Formula : C10H15NO2S

  • Molecular Weight : 213.3

20 % OFF
stdClass Object
(
    [pname] => 4-(tert-Butyl)benzene-1-sulfonyl chloride
    [catalogue_number] => PA 02 21520
    [category_ids] => ,85,83,78,70,82,
    [chemical_name] => 
    [weight] => 232.73
    [form] => C10H13ClO2S
    [cas] => 15084-51-2
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PA 02 21520

4-(tert-Butyl)benzene-1-sulfonyl chloride


  • Catalogue No.:PA 02 21520

  • CAS :

    15084-51-2

  • Molecular Formula : C10H13ClO2S

  • Molecular Weight : 232.73

20 % OFF
stdClass Object
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    [pname] => 4-(tert-Butyl)-N-[6-chloro-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl] benzenesulfonamide
    [catalogue_number] => PA 02 21530
    [category_ids] => ,85,83,78,70,82,
    [chemical_name] => 
    [weight] => 526.01
    [form] => C25H24ClN5O4S
    [cas] => 150727-06-3
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PA 02 21530

4-(tert-Butyl)-N-[6-chloro-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl] benzenesulfonamide


  • Catalogue No.:PA 02 21530

  • CAS :

    150727-06-3

  • Molecular Formula : C25H24ClN5O4S

  • Molecular Weight : 526.01

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    [pname] => 4-(tert-Butyl)-N-[6-hydroxy-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl]benzenesulfonamide
    [catalogue_number] => PA 02 21540
    [category_ids] => ,70,71,78,79,80,82,83,85,88,
    [chemical_name] => 
    [weight] => 507.56
    [form] => C25H25N5O5S
    [cas] => 174227-14-6
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PA 02 21540

4-(tert-Butyl)-N-[6-hydroxy-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl]benzenesulfonamide


  • Catalogue No.:PA 02 21540

  • CAS :

    174227-14-6

  • Molecular Formula : C25H25N5O5S

  • Molecular Weight : 507.56

20 % OFF
stdClass Object
(
    [pname] => 6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4(3H)-one
    [catalogue_number] => PA 02 21550
    [category_ids] => 88,85,83,82,80,79,78,71,70
    [chemical_name] => 
    [weight] => 330.73
    [form] => C15H11ClN4O3
    [cas] => 1268612-27-6
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PA 02 21550

6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4(3H)-one


  • Catalogue No.:PA 02 21550

  • CAS :

    1268612-27-6

  • Molecular Formula : C15H11ClN4O3

  • Molecular Weight : 330.73

20 % OFF
stdClass Object
(
    [pname] => 4-(tert-Butyl)-N-(6-methoxy-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide
    [catalogue_number] => PA 02 21600
    [category_ids] => ,79,80,71,85,83,78,70,82,88,
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    [weight] => 521.59
    [form] => C26H27N5O5S
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PA 02 21600

4-(tert-Butyl)-N-(6-methoxy-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide


  • Catalogue No.:PA 02 21600

  • CAS :

    NA

  • Molecular Formula : C26H27N5O5S

  • Molecular Weight : 521.59

20 % OFF
stdClass Object
(
    [pname] => N-(6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)-4-isopropylbenzenesulfonamide
    [catalogue_number] => PA 02 21610
    [category_ids] => ,79,80,71,85,83,78,70,82,88,
    [chemical_name] => 
    [weight] => 537.59
    [form] => C26H27N5O6S
    [cas] => 1268612-24-3
    [pslug] => 1268612-24-3-n-6-2-hydroxyethoxy-5-2-methoxyphenoxy-2-2-bipyrimidin-4-yl-4-isopropylbenzenesulfonamide-pa0221610
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PA 02 21610

N-(6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)-4-isopropylbenzenesulfonamide


  • Catalogue No.:PA 02 21610

  • CAS :

    1268612-24-3

  • Molecular Formula : C26H27N5O6S

  • Molecular Weight : 537.59

20 % OFF
stdClass Object
(
    [pname] => Bosentan Dimer Impurity
    [catalogue_number] => PA 02 21620
    [category_ids] => ,79,80,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 1041.16
    [form] => C52H52N10O10S2
    [cas] => 1097263-60-9
    [pslug] => 1097263-60-9-bosentan-dimer-impurity-pa0221620
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PA 02 21620

Bosentan Dimer Impurity


  • Catalogue No.:PA 02 21620

  • CAS :

    1097263-60-9

  • Molecular Formula : C52H52N10O10S2

  • Molecular Weight : 1041.16

20 % OFF
stdClass Object
(
    [pname] => 4-(tert-Butyl)-N-((4-(tert-Butyl)phenyl)sulfonyl)benzenesulfonamide
    [catalogue_number] => PA 02 0211000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 409.56
    [form] => C20H27NO4S2
    [cas] => 1355251-10-3
    [pslug] => 1355251-10-3-4-tert-butyl-n-4-tert-butyl-phenyl-sulfonyl-benzenesulfonamide-pa020211000
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PA 02 0211000

4-(tert-Butyl)-N-((4-(tert-Butyl)phenyl)sulfonyl)benzenesulfonamide


  • Catalogue No.:PA 02 0211000

  • CAS :

    1355251-10-3

  • Molecular Formula : C20H27NO4S2

  • Molecular Weight : 409.56

20 % OFF
stdClass Object
(
    [pname] => 4-(tert-Butyl)-N-(6-ethoxy-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide
    [catalogue_number] => PA 02 0211002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 535.62
    [form] => C27H29N5O5S
    [cas] => 157415-45-7
    [pslug] => 157415-45-7-4-tert-butyl-n-6-ethoxy-5-2-methoxyphenoxy-2-2-bipyrimidin-4-yl-benzenesulfonamide-pa020211002
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PA 02 0211002

4-(tert-Butyl)-N-(6-ethoxy-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide


  • Catalogue No.:PA 02 0211002

  • CAS :

    157415-45-7

  • Molecular Formula : C27H29N5O5S

  • Molecular Weight : 535.62

20 % OFF
stdClass Object
(
    [pname] => Desmethyl Bosentan
    [catalogue_number] => PA 02 0211003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 537.59
    [form] => C26H27N5O6S
    [cas] => 253688-61-8
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PA 02 0211003

Desmethyl Bosentan


  • Catalogue No.:PA 02 0211003

  • CAS :

    253688-61-8

  • Molecular Formula : C26H27N5O6S

  • Molecular Weight : 537.59

20 % OFF
stdClass Object
(
    [pname] => 2-((6-((4-(tert-Butyl)phenyl)sulfonamido)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)oxy)ethyl Acetate
    [catalogue_number] => PA 02 0211005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 593.66
    [form] => C29H31N5O7S
    [cas] => 1160515-53-6
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PA 02 0211005

2-((6-((4-(tert-Butyl)phenyl)sulfonamido)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)oxy)ethyl Acetate


  • Catalogue No.:PA 02 0211005

  • CAS :

    1160515-53-6

  • Molecular Formula : C29H31N5O7S

  • Molecular Weight : 593.66

20 % OFF
stdClass Object
(
    [pname] => 4-(tert-Butyl)-N-(6-(2-(2-hydroxyethoxy)ethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide
    [catalogue_number] => PA 02 0211006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 595.67
    [form] => C29H33N5O7S
    [cas] => 1257099-43-6
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PA 02 0211006

4-(tert-Butyl)-N-(6-(2-(2-hydroxyethoxy)ethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide


  • Catalogue No.:PA 02 0211006

  • CAS :

    1257099-43-6

  • Molecular Formula : C29H33N5O7S

  • Molecular Weight : 595.67

20 % OFF
stdClass Object
(
    [pname] => Hydroxy Bosentan
    [catalogue_number] => PA 02 21560
    [category_ids] => ,80,71,76,75,85,83,78,70,82,88,
    [chemical_name] => 
    [weight] => 567.61
    [form] => C27H29N5O7S
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PA 02 21560

Hydroxy Bosentan


  • Catalogue No.:PA 02 21560

  • CAS :

    253688-60-7

  • Molecular Formula : C27H29N5O7S

  • Molecular Weight : 567.61

stdClass Object
(
    [pname] => 4-(tert-Butyl)-N,N-bis(6-chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide
    [catalogue_number] => PA 02 21580
    [category_ids] => ,79,80,71,85,83,78,70,82,88,
    [chemical_name] => 
    [weight] => 838.72
    [form] => C40H33Cl2N9O6S
    [cas] => NA
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PA 02 21580

4-(tert-Butyl)-N,N-bis(6-chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide


  • Catalogue No.:PA 02 21580

  • CAS :

    NA

  • Molecular Formula : C40H33Cl2N9O6S

  • Molecular Weight : 838.72

stdClass Object
(
    [pname] => N,N'-[5-(2-Methoxyphenoxy)[2,2'-bipyrimidine]-4,6-diyl]bis[4-(1,1-dimethylethyl)benzenesulfonamide]
    [catalogue_number] => PA 02 21590
    [category_ids] => ,79,80,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 702.84
    [form] => C35H38N6O6S2
    [cas] => 1218951-81-5
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PA 02 21590

N,N'-[5-(2-Methoxyphenoxy)[2,2'-bipyrimidine]-4,6-diyl]bis[4-(1,1-dimethylethyl)benzenesulfonamide]


  • Catalogue No.:PA 02 21590

  • CAS :

    1218951-81-5

  • Molecular Formula : C35H38N6O6S2

  • Molecular Weight : 702.84

stdClass Object
(
    [pname] => 2-tert-Butylbenzenesulfonamide
    [catalogue_number] => PA 02 21630
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    [chemical_name] => 
    [weight] => 213.3
    [form] => C10H15NO2S
    [cas] => 193013-72-8
    [pslug] => 193013-72-8-2-tert-butylbenzenesulfonamide-pa0221630
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PA 02 21630

2-tert-Butylbenzenesulfonamide


  • Catalogue No.:PA 02 21630

  • CAS :

    193013-72-8

  • Molecular Formula : C10H15NO2S

  • Molecular Weight : 213.3

stdClass Object
(
    [pname] => 4-(tert-Butyl)-N-(5-(2-methoxyphenoxy)-6-(vinyloxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide
    [catalogue_number] => PA 02 0211001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 533.6
    [form] => C27H27N5O5S
    [cas] => 1257099-44-7
    [pslug] => 1257099-44-7-4-tert-butyl-n-5-2-methoxyphenoxy-6-vinyloxy-2-2-bipyrimidin-4-yl-benzenesulfonamide-pa020211001
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PA 02 0211001

4-(tert-Butyl)-N-(5-(2-methoxyphenoxy)-6-(vinyloxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide


  • Catalogue No.:PA 02 0211001

  • CAS :

    1257099-44-7

  • Molecular Formula : C27H27N5O5S

  • Molecular Weight : 533.6

stdClass Object
(
    [pname] => Hydroxy O-Desmethyl Bosentan
    [catalogue_number] => PA 02 0211004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 553.59
    [form] => C26H27N5O7S
    [cas] => 253688-62-9
    [pslug] => 253688-62-9-hydroxy-o-desmethyl-bosentan-pa020211004
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PA 02 0211004

Hydroxy O-Desmethyl Bosentan


  • Catalogue No.:PA 02 0211004

  • CAS :

    253688-62-9

  • Molecular Formula : C26H27N5O7S

  • Molecular Weight : 553.59

stdClass Object
(
    [pname] => Cesium ((4-(tert-butyl)phenyl)sulfonyl)(6-chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)amide
    [catalogue_number] => PA 02 0211008
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 657.91
    [form] => C25H23ClCsN5O4S
    [cas] => 1218951-79-1
    [pslug] => 1218951-79-1-cesium-4-tert-butyl-phenyl-sulfonyl-6-chloro-5-2-methoxyphenoxy-2-2-bipyrimidin-4-yl-amide-pa020211008
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PA 02 0211008

Cesium ((4-(tert-butyl)phenyl)sulfonyl)(6-chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)amide


  • Catalogue No.:PA 02 0211008

  • CAS :

    1218951-79-1

  • Molecular Formula : C25H23ClCsN5O4S

  • Molecular Weight : 657.91